6177 results
JACC. Cardiovascular imaging,
Volume 14, Issue 8, 17 3 2021, Pages 1581-1583
Computed Tomography to Select Patients for Transcatheter Mitral Valve Replacement: The Challenge of Standardization.
Delgado V, van Rosendael PJ
Abstract
Cited 4 times since 2021 (1 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 16 3 2021, Pages 644193
Validation and Feasibility of Echocardiographic Assessment of Systemic Right Ventricular Function: Serial Correlation With MRI.
Zandstra TE, Jongbloed MRM, Widya RL, Ten Harkel ADJ, Holman ER, Mertens BJA, Vliegen HW, Egorova AD, Schalij MJ, Kiès P
Background: Inherent to its geometry, echocardiographic imaging of the systemic right ventricle (RV) is challenging. Therefore, echocardiographic assessment of systemic RV function may not always be feasible and/or reproducible in daily practice. Here, we aim to validate the usefulness of a comprehensive range of 32 echocardiographic measurements of systemic RV function in a longitudinal cohort by serial assessment of their correlations with cardiac magnetic resonance (CMR)-derived systemic RV e...
Abstract
Cited 8 times since 2021 (1.9 per year)
source: EuropePMC
Teaching and learning in medicine,
Volume 33, Issue 5, 15 3 2021, Pages 473-482
What Were You Thinking? Medical Students' Metacognition and Perceptions of Self-Regulated Learning.
Versteeg M, Bressers G, Wijnen-Meijer M, Ommering BWC, de Beaufort AJ, Steendijk P
Phenomenon: As a component of self-regulated learning, metacognition is gaining attention in the medical education research community. Metacognition, simply put, is thinking about one's thinking. Having a metacognitive habit of mind is essential for healthcare professionals. This study identified the metacognitive competencies of medical students as they completed a conceptual learning task, and provided insight into students' perceptions of self-regulated learning in their curriculum....
Abstract
Cited 12 times since 2021 (2.9 per year)
source: EuropePMC
Diabetes care,
Volume 44, Issue 5, 15 3 2021, Pages 1219-1227
Relation of Lipoprotein(a) Levels to Incident Type 2 Diabetes and Modification by Alirocumab Treatment.
Schwartz GG, Szarek M, Bittner VA, Bhatt DL, Diaz R, Goodman SG, Jukema JW, Loy M, Manvelian G, Pordy R, White HD, Steg PG, ODYSSEY OUTCOMES Committees and Investigators
Objective: In observational data, lower levels of lipoprotein(a) have been associated with greater prevalence of type 2 diabetes. Whether pharmacologic lowering of lipoprotein(a) influences incident type 2 diabetes is unknown. We determined the relationship of lipoprotein(a) concentration with incident type 2 diabetes and effects of treatment with alirocumab, a PCSK9 inhibitor. Research design and methods: In the ODYSSEY OUTCOMES trial alirocumab was compared with placebo in patients with acute...
Abstract
Cited 31 times since 2021 (7.5 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 4, 15 3 2021, Pages e009135
Posterior Left Atrial Adipose Tissue Attenuation Assessed by Computed Tomography and Recurrence of Atrial Fibrillation After Catheter Ablation.
El Mahdiui M, Simon J, Smit JM, Kuneman JH, van Rosendael AR, Steyerberg EW, van der Geest RJ, Száraz L, Herczeg S, Szegedi N, Gellér L, Delgado V, Merkely B, Bax JJ, Maurovich-Horvat P
[Figure: see text].
Abstract
Cited 13 times since 2021 (3.2 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 3, 13 2 2021, Pages 1924-1932
Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry.
Kato K, Cammann VL, Napp LC, Szawan KA, Micek J, Dreiding S, Levinson RA, Petkova V, Würdinger M, Patrascu A, Sumalinog R, Gili S, Clarenbach CF, Kohler M, Wischnewsky M, Citro R, Vecchione C, Bossone E, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Heiner S, D'Ascenzo F, Dichtl W, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Budnik M, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Kozel M, Tousek P, Winchester DE, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Sano M, Ishibashi I, Takahara M, Himi T, Kobayashi Y, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm M, Maier LS, Pinto FJ, Widimský P, Feli
Aims: Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence of acute pulmonary triggers in patients with TTS and their impact on outcomes. Methods and results: Patients with TTS were enrolled from the International Takotsubo Registry and screened for triggering factors and comorbidities. Patients were categorized into three groups (acute pulmonary trigger, chronic lung disease, and no lung disease) to compare clinical charac...
Abstract
Cited 55 times since 2021 (13.4 per year)
source: EuropePMC
Atherosclerosis,
Volume 324, 13 2 2021, Pages 46-51
Atherogenic index of plasma and the risk of rapid progression of coronary atherosclerosis beyond traditional risk factors.
Won KB, Heo R, Park HB, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, de Araújo Gonçalves P, Leipsic JA, Lee SE, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ
Background and aims: The atherogenic index of plasma (AIP) has been suggested as a marker of plasma atherogenicity. This study aimed to assess the association between AIP and the rapid progression of coronary atherosclerosis using serial coronary computed tomography angiography (CCTA). Methods: A total of 1488 adults (60.9 ± 9.2 years, 58.9% male) who underwent serial CCTA with a median inter-scan period of 3.4 years were included. AIP was defined as the base 10 logarithm of the ratio of the con...
Abstract
Cited 4 times since 2021 (1 per year)
source: EuropePMC
Cardiovascular and interventional radiology,
Volume 44, Issue 7, 11 2 2021, Pages 1116-1120
Partial Right Atrial Inflow Occlusion for Transient Systemic Hypotension During Deployment of Thoracic Stentgrafts.
Pietersen LC, van der Meer RW, Alders DJC, van Schaik J, Eefting D, van Rijswijk CSP
Purpose: Temporary balloon occlusion of the inferior vena cava to lower cardiac output is a relatively infrequently used technique to induce controlled systemic hypotension. In this technical note, we describe the feasibility, reliability, and safety of partial occlusion of right atrial inflow and the effect on systemic blood pressure during the deployment of a thoracic stentgraft. Materials and methods: Twenty consecutive patients undergoing thoracic endovascular aortic repair, with proximal la...
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie,
Volume 28, Issue 4, 11 2 2021, Pages 278-284
The effect of foot reflexology on procedural pain before heel lancing in neonates.
Yilmaz D, Yilmaz D, Yilmaz Kurt F
Objective: This study was designed to investigate the effect of foot reflexology on alleviating term neonates' invasive pain caused by heel lance. Methods: In this quasi-experimental study, 60 healthy neonates were recruited and divided into a reflexology group (n=30) and a control (n=30) group. The study design was quasi-experimental since the randomisation method was not used in the assignment of newborns to the groups. While the reflexology group received foot reflexology for an average...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 37, Issue 7, 10 2 2021, Pages 2311-2321
Sex differences in coronary plaque changes assessed by serial computed tomography angiography.
El Mahdiui M, Smit JM, van Rosendael AR, Neglia D, Knuuti J, Saraste A, Buechel RR, Teresinska A, Pizzi MN, Roque A, Magnacca M, Mertens BJ, Caselli C, Rocchiccioli S, Parodi O, Pelosi G, Scholte AJ
Long-term data on sex-differences in coronary plaque changes over time is lacking in a low-to-intermediate risk population of stable coronary artery disease (CAD). The aim of this study was to evaluate the role of sex on long-term plaque progression and evolution of plaque composition. Furthermore, the influence of menopause on plaque progression and composition was also evaluated. Patients that underwent a coronary computed tomography angiography (CTA) were prospectively included to undergo a f...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 44, Issue 4, 9 2 2021, Pages 657-666
The prognostic value of J-wave pattern for recurrence of ventricular tachycardia after catheter ablation in patients with myocardial infarction.
Naruse Y, de Riva M, Watanabe M, Wijnmaalen AP, Venlet J, Timmer M, Schalij MJ, Zeppenfeld K
Background: J-waves and fragmented QRS (fQRS) on surface ECGs have been associated with the occurrence of ventricular tachyarrhythmias. Whether these non-invasive parameters can also predict ventricular tachycardia (VT) recurrence after radiofrequency catheter ablation (RFCA) is unknown. Of interest, patients with a wide QRS-complex have been excluded from clinical studies on J-waves, although a J-wave like pattern has been described for wide QRS. Methods: We retrospectively included 168 patient...
Abstract
Cited 10 times since 2021 (2.4 per year)
source: EuropePMC
Human & experimental toxicology,
Volume 40, Issue 9, 9 2 2021, Pages 1445-1462
Modulation of cigarette smoke extract-induced human bronchial epithelial damage by eucalyptol and curcumin.
Reis R, Orak D, Yilmaz D, Cimen H, Sipahi H
Smoking is one of the most important leading death cause worldwide. From a toxicological perspective, cigarette smoke serves hazards especially for the human being exposed to passive smoke. Over the last decades, the effects of natural compounds on smoking-mediated respiratory diseases such as COPD, asthma, and lung cancer have been under investigation, as well as the mechanistic aspects of disease progression. In the present study, the protective mechanism of eucalyptol (EUC), curcumin (CUR), a...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 29, Issue 6, 8 2 2021, Pages 311-317
The first multicentre study on coronary anomalies in the Netherlands: MuSCAT.
Koppel CJ, Driesen BW, de Winter RJ, van den Bosch AE, van Kimmenade R, Wagenaar LJ, Jukema JW, Hazekamp MG, van der Kley F, Jongbloed MRM, Kiès P, Egorova AD, Verheijen DBH, Damman P, Schoof PH, Wilschut J, Stoel M, Speekenbrink RGH, Voskuil M, Vliegen HW
Background: Current guidelines on coronary anomalies are primarily based on expert consensus and a limited number of trials. A gold standard for diagnosis and a consensus on the treatment strategy in this patient group are lacking, especially for patients with an anomalous origin of a coronary artery from the opposite sinus of Valsalva (ACAOS) with an interarterial course. Aim: To provide evidence-substantiated recommendations for diagnostic work-up, treatment and follow-up of patients with anom...
Abstract
Cited 17 times since 2021 (4.1 per year)
source: EuropePMC
eLife,
Volume 10, 8 2 2021, Pages e62161
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
Kirstein N, Buschle A, Wu X, Krebs S, Blum H, Kremmer E, Vorberg IM, Hammerschmidt W, Lacroix L, Hyrien O, Audit B, Schepers A
Eukaryotic DNA replication initiates during S phase from origins that have been licensed in the preceding G1 phase. Here, we compare ChIP-seq profiles of the licensing factors Orc2, Orc3, Mcm3, and Mcm7 with gene expression, replication timing, and fork directionality profiles obtained by RNA-seq, Repli-seq, and OK-seq. Both, the origin recognition complex (ORC) and the minichromosome maintenance complex (MCM) are significantly and homogeneously depleted from transcribed genes, enriched at gene...
Abstract
Cited 53 times since 2021 (12.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 148, 3 1 2021, Pages 138-145
Right Ventricular-Pulmonary Arterial Coupling in Secondary Tricuspid Regurgitation.
Fortuni F, Butcher SC, Dietz MF, van der Bijl P, Prihadi EA, De Ferrari GM, Ajmone Marsan N, Bax JJ, Delgado V
Chronic pressure-overload induces right ventricular (RV) adaptation to maintain RV-pulmonary arterial (PA) coupling. RV remodeling is frequently associated with secondary tricuspid regurgitation (TR) which may accelerate uncoupling. Our aim is to determine whether the non-invasive analysis of RV-PA coupling could improve risk stratification in patients with secondary TR. A total of 1,149 patients (median age 72[IQR, 63 to 79] years, 51% men) with moderate or severe secondary TR were included. RV...
Abstract
Cited 9 times since 2021 (2.2 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 3, 2 1 2021, Pages 2306-2309
Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies.
Povsic TJ, Sanz-Ruiz R, Climent AM, Bolli R, Taylor DA, Gersh BJ, Menasché P, Perin EC, Pompilio G, Atsma DE, Badimon L, DeMaria AN, Hare JM, Henry TD, Janssens S, Kastrup J, Torella D, Traverse JH, Willerson JT, Fernández-Avilés F
The concept that cell-based repair of myocardial injury might be possible was introduced almost two decades ago; however, the field of cardiovascular reparative medicine has been criticized as translation to clinically effective approaches has been slow. The recent retraction of a series of papers has further impacted perception of this area of research. As researchers, clinicians, and teachers in this field, we felt it incumbent to critically appraise the current state of cardiac cell repair, d...
Abstract
Cited 25 times since 2021 (6 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 14, Issue 3, 2 1 2021, Pages e012072
Global Left Ventricular Myocardial Work Efficiency and Long-Term Prognosis in Patients After ST-Segment-Elevation Myocardial Infarction.
Lustosa RP, Butcher SC, van der Bijl P, El Mahdiui M, Montero-Cabezas JM, Kostyukevich MV, Rocha De Lorenzo A, Knuuti J, Ajmone Marsan N, Bax JJ, Delgado V
Background: Left ventricular (LV) global longitudinal strain has demonstrated incremental prognostic value over LV ejection fraction in patients with ST-segment-elevation myocardial infarction. However, LV global longitudinal strain does not take into consideration the effect of afterload. Novel speckle-tracking echocardiographic indices of myocardial work integrate blood pressure measurements (afterload) with LV global longitudinal strain. The present study aimed to investigate the prognostic v...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 10, Issue 5, 1 1 2021, Pages 932
Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes.
Blauw LL, Noordam R, van der Laan SW, Trompet S, Kooijman S, van Heemst D, Jukema JW, van Setten J, de Borst GJ, Tybjærg-Hansen A, Pasterkamp G, Berbée JFP, Rensen PCN
We analyzed the effects of the common BMI-increasing melanocortin 4 receptor (MC4R) rs17782313-C allele with a minor allele frequency of 0.22-0.25 on (1) cardiovascular disease outcomes in two large population-based cohorts (Copenhagen City Heart Study and Copenhagen General Population Study, n = 106,018; and UK Biobank, n = 357,426) and additionally in an elderly population at risk for cardiovascular disease (n = 5241), and on (2) atherosclerotic plaque phenotypes in samples of patients who und...
Abstract
Cited 9 times since 2021 (2.2 per year)
source: EuropePMC
European heart journal. Cardiovascular pharmacotherapy,
Volume 7, Issue 2, 1 1 2021, Pages 94-103
Comparison of P2Y12 receptor inhibitors in patients with ST-elevation myocardial infarction in clinical practice: a propensity score analysis of five contemporary European registries.
De Luca L, Zeymer U, Claeys MJ, Dörler J, Erne P, Matter CM, Radovanovic D, Weidinger F, Lüscher TF, Jukema JW, PIRAEUS group
Aims: Among acute coronary syndromes (ACS), ST-segment elevation myocardial infarction (STEMI) has the most severe early clinical course. Recent randomized clinical trials have demonstrated that novel antithrombotic therapies improve in-hospital outcomes in STEMI patients. We aimed to describe the effectiveness and safety of P2Y12 receptor inhibitors in clinical practice in patients with STEMI based on data from contemporary European ACS registries. Methods and results: Five registries from the...
Abstract
Open heart,
Volume 8, Issue 1, 1 1 2021, Pages e001252
Patient information portal for congenital aortic and pulmonary valve disease: a stepped-wedge cluster randomised trial.
Etnel JRG, Bons LR, De Heer F, Robbers-Visser D, Van Beynum IM, Straver B, Jongbloed MR, Kiès P, Slieker MG, Van Dijk APJ, Kluin J, Bertels RA, Utens EMWJ, The R, Van Galen E, Mulder BJM, Blom NA, Hazekamp MG, Roos-Hesselink JW, Helbing WA, Bogers AJJC, Takkenberg JJM
Background: In response to an increased need for patient information in congenital heart disease, we previously developed an online, evidence-based information portal for patients with congenital aortic and pulmonary valve disease. To assess its effectiveness, a stepped-wedge cluster randomised trial was conducted. Methods: Adult patients and caregivers of paediatric patients with congenital aortic and/or pulmonary valve disease and/or tetralogy of Fallot who visited the outpatient clinic at any...
Abstract
