Research

Publications

Below you can find a list of our published research.

6173 results

Cited 47 times since 2004 (2.3 per year) source: EuropePMC

The American journal of cardiology, Volume 94, Issue 3, 1 1 2004, Pages 284-288 Quantification of myocardial infarct size and transmurality by contrast-enhanced magnetic resonance imaging in men. Schuijf JD, Kaandorp TA, Lamb HJ, van der Geest RJ, Viergever EP, van der Wall EE, de Roos A, Bax JJ

Contrast-enhanced magnetic resonance (ce-MR) imaging allows precise delineation of infarct transmurality. An issue of debate is whether data analysis should be performed visually or quantitatively. Accordingly, a head-to-head comparison was performed between visual and quantitative analyses of infarct transmurality on ce-MR imaging. In addition, infarct transmurality was related to the severity of wall motion abnormalities at rest. In 27 patients with long-term ischemic left ventricular (LV) dys... Abstract

Cited 114 times since 2004 (5.5 per year) source: EuropePMC

The American journal of cardiology, Volume 94, Issue 4, 1 1 2004, Pages 427-430 Feasibility of assessment of coronary stent patency using 16-slice computed tomography. Schuijf JD, Bax JJ, Jukema JW, Lamb HJ, Warda HM, Vliegen HW, de Roos A, van der Wall EE

Intracoronary stent implantation is a frequently performed procedure in the treatment of stenoses in coronary arteries, but in-stent restenosis occurs in approximately 10% to 15% of patients. A noninvasive diagnostic procedure to evaluate in-stent restenosis would therefore be of great benefit. We investigated the feasibility of assessing stent patency with 16-slice computed tomography. Multislice computed tomography (MSCT) was performed in 22 patients with previously implanted stents. For each... Abstract

Cited 5 times since 2004 (0.2 per year) source: EuropePMC

The American journal of cardiology, Volume 94, Issue 3, 1 1 2004, Pages 289-293 Differential prognostic significance of peri-infarction versus remote myocardial ischemia on stress technetium-99m sestamibi tomography in patients with healed myocardial infarction. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Poldermans D

Peri-infarction and remote myocardial ischemia involve different myocardial substrates, but their differential clinical implications have not been previously studied. We assessed the differential prognostic significance of peri-infarction and remote ischemia during long-term follow-up in patients with healed myocardial infarction. We studied 345 patients (59 +/- 12 years old; 282 men) with previous myocardial infarction who demonstrated reversible perfusion abnormalities on exercise or dobutamin... Abstract

Cited 5 times since 2004 (0.2 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 44, Issue 4, 1 1 2004, Pages 937; author reply 937-8 Prognostic value of left ventricular dyssynchrony in patients with heart failure. Bax JJ, van dWall EE, Schalij MJ

Abstract

Cited 2 times since 2004 (0.1 per year) source: EuropePMC

Coronary artery disease, Volume 15, Issue 5, 1 1 2004, Pages 269-275 Does resting two-dimensional echocardiography identify patients with ischemic cardiomyopathy and low likelihood of functional recovery after coronary revascularization? Rizzello V, Bax JJ, Schinkel AF, Boersma E, Bountioukos M, Vourvouri EC, Crea F, Biagini E, Elhendy A, Roelandt JR, Poldermans D

Objective: To evaluate the potential of a simple and widely available technique as two-dimensional (2D) echocardiography to identify patients with ischemic cardiomyopathy and low likelihood of functional recovery after coronary revascularization. Methods: Two-dimensional echocardiography and radionuclide ventriculography (RNV) were performed before coronary revascularization in 94 patients with ischemic cardiomyopathy. Left ventricular ejection fraction (LVEF) was measured by RNV. Regional wall... Abstract

Cited 76 times since 2004 (3.7 per year) source: EuropePMC

Journal of virology, Volume 78, Issue 15, 1 1 2004, Pages 8264-8270 Recovery of human metapneumovirus genetic lineages a and B from cloned cDNA. Herfst S, de Graaf M, Schickli JH, Tang RS, Kaur J, Yang CF, Spaete RR, Haller AA, van den Hoogen BG, Osterhaus AD, Fouchier RA

Human metapneumovirus (hMPV) is a newly discovered pathogen associated with respiratory tract illness, primarily in young children, immunocompromised individuals, and the elderly. The genomic sequence of the prototype hMPV isolate NL/1/00 without the terminal leader and trailer sequences has been reported previously. Here we describe the leader and trailer sequences of two hMPV isolates, NL/1/00 and NL/1/99, representing the two main genetic lineages of hMPV. Minigenome constructs in which the g... Abstract

Cited 3 times since 2004 (0.1 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 20, Issue 4, 1 1 2004, Pages 341-344 Coronary stent imaging with multidetector row computed tomography. Schuijf JD, Bax JJ, Jukema JW, Lamb HJ, Dirksen MS, van der Wall EE, de Roos A

Multidetector row Computed Tomography (MDCT) is developing rapidly as a potential non-invasive imaging method for the direct visualization of coronary arteries in patients presenting with suspected coronary artery disease. Recent technical improvements have led to improved spatial and temporal resolution and may even allow evaluation of coronary stents, which has remained difficult due to the small diameter and radio-opaque material. We describe two cases, a 65- and a 72-year old patient. Both p... Abstract

Cited 6 times since 2004 (0.3 per year) source: EuropePMC

Thrombosis and haemostasis, Volume 92, Issue 2, 1 1 2004, Pages 425-426 Acute myocardial infarction during substitution with recombinant factor VIII concentrate in a patient with mild haemophilia A. Kerkhoffs JL, Atsma DE, Oemrawsingh PV, Eikenboom J, Van der Meer FJ

Abstract

Cited 44 times since 2004 (2.1 per year) source: EuropePMC

Current opinion in lipidology, Volume 15, Issue 4, 1 1 2004, Pages 393-398 CETP gene variation: relation to lipid parameters and cardiovascular risk. Boekholdt SM, Kuivenhoven JA, Hovingh GK, Jukema JW, Kastelein JJ, van Tol A

Purpose of review: Over the past decade lowering of low-density lipoprotein-cholesterol levels has been established as the foundation for preventing coronary artery disease, but substantial additional risk reduction remains to be gained by modifying risk factors other than low-density lipoprotein-cholesterol. Raising high-density lipoprotein-cholesterol levels by inhibiting activity of the cholesteryl ester transfer protein (CETP) is a prime target. Research on naturally occurring variants in th... Abstract

Cited 3 times since 2004 (0.1 per year) source: EuropePMC

Radiology, Volume 232, Issue 3, 23 4 2004, Pages 915-920 Blood flow in coronary artery bypass vein grafts: volume versus velocity at cardiovascular MR imaging. Salm LP, Langerak SE, Vliegen HW, Jukema JW, Bax JJ, Zwinderman AH, van der Wall EE, de Roos A, Lamb HJ

Forty-nine patients with previous bypass surgery underwent coronary angiography and cardiovascular magnetic resonance (MR) imaging of single-vein bypass grafts. Volume flow and velocity analyses were performed and compared on MR velocity maps. Bland-Altman analysis showed close agreement between the two types of analysis. Comparison of areas under the receiver operating characteristic curve revealed no significant differences between the analyses for detection of stenoses of 70% or greater. Diag... Abstract

Cited 30 times since 2004 (1.4 per year) source: EuropePMC

Anatomy and embryology, Volume 208, Issue 5, 10 2 2004, Pages 389-393 The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Poelmann RE, Jongbloed MR, Molin DG, Fekkes ML, Wang Z, Fishman GI, Doetschman T, Azhar M, Gittenberger-de Groot AC

In this study we present data on the spatial relationship between neural crest-derived cells (NCC) and the specialized cardiac conduction system (CCS) in the developing murine heart. Using Wnt1-Cre/R26R conditional reporter mice that express beta-galactosidase from ROSA26 upon Cre-mediated recombination, two populations of NCC are seen: one migrates through the arterial pole and contributes to the bundle branches, whereas the second population enters by way of the venous pole and provides cells... Abstract

Cited 44 times since 2004 (2.1 per year) source: EuropePMC

European heart journal, Volume 25, Issue 13, 1 1 2004, Pages 1163-1170 Current PTCA practice and clinical outcomes in The Netherlands: the real world in the pre-drug-eluting stent era. Agema WR, Monraats PS, Zwinderman AH, De Winter RJ, Tio RA, Doevendans PA, Waltenberger J, De Maat MP, Frants RR, Atsma DE, Van Der Laarse A, Van Der Wall EE, Jukema JW

Aims: To document the practice of interventional cardiology and the clinical restenosis rate, as well as the risk factors for clinical restenosis in an unselected population of patients in daily practice and to provide a perspective for the need of new devices such as drug-eluting stents. Methods and results: A total of 3177 consecutive patients, who underwent successful percutaneous transluminal coronary angioplasty (PTCA) in the Netherlands, were included. Patients with acute myocardial infarc... Abstract

Cited 26 times since 2004 (1.2 per year) source: EuropePMC

The American journal of cardiology, Volume 94, Issue 1, 1 1 2004, Pages 130-132 Effect of left ventricular remodeling after cardiac resynchronization therapy on frequency of ventricular arrhythmias. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, St John Sutton M, van Erven L, van der Wall EE, Schalij MJ

We evaluated whether cardiac resynchronization therapy affects the prevalence of ventricular tachycardia in relation to reverse remodeling in patients with end-stage heart failure. Clinical, echocardiographic, and implantable cardioverter-defibrillator (ICD) data of 17 patients with ICDs were obtained before and after they had received an upgrade to an ICD-cardiac resynchronization therapy device. Abstract

Cited 22 times since 2004 (1.1 per year) source: EuropePMC

The American journal of medicine, Volume 117, Issue 1, 1 1 2004, Pages 1-9 Long-term prognostic value of dobutamine stress echocardiography compared with myocardial perfusion scanning in patients unable to perform exercise tests. Schinkel AF, Bax JJ, Elhendy A, van Domburg RT, Valkema R, Vourvouri E, Bountioukos M, Rizzello V, Biagini E, Agricola E, Krenning EP, Simoons ML, Poldermans D

Purpose: To compare the long-term prognostic value of dobutamine stress echocardiography and dobutamine stress single photon emission computed tomography (SPECT) in patients unable to perform an exercise test. Methods: We assessed the prognostic value of dobutamine stress technetium 99m ((99m)Tc)-sestamibi SPECT and dobutamine stress echocardiography in 301 patients who were unable to perform exercise tests. Outcomes during a mean (+/- SD) follow-up of 7.3 +/- 2.8 years were overall death, cardi... Abstract

Cited 13 times since 2004 (0.6 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 17, Issue 7, 1 1 2004, Pages 739-743 Prognostic value of dobutamine stress echocardiography in patients with normal left ventricular systolic function. Elhendy A, Schinkel AF, Bax JJ, Van Domburg RT, Poldermans D

Background: Patients with normal left ventricular systolic function are considered to be at a relatively low risk for cardiac events. There are scarce data regarding association of ischemia on stress imaging techniques with outcome in these patients. Objectives: We sought to assess the prognostic significance of dobutamine-induced myocardial ischemia for patients with normal left ventricular systolic function. Methods: We studied 528 patients with normal baseline left ventricular systolic functi... Abstract

Cited 251 times since 2004 (12.1 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 44, Issue 1, 1 1 2004, Pages 1-9 Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal. Bax JJ, Ansalone G, Breithardt OA, Derumeaux G, Leclercq C, Schalij MJ, Sogaard P, St John Sutton M, Nihoyannopoulos P

Cardiac resynchronization therapy (CRT) has been proposed as an alternative treatment in patients with severe, drug-refractory heart failure. The clinical results are promising, and improvement in symptoms, exercise capacity, and systolic left ventricular (LV) function have been demonstrated after CRT, accompanied by a reduction in hospitalization and a superior survival as compared with optimized medical therapy alone. However, 20% to 30% of patients do not respond to CRT. Currently, patients a... Abstract

Cited 12 times since 2004 (0.6 per year) source: EuropePMC

Pediatric hematology and oncology, Volume 21, Issue 5, 1 1 2004, Pages 403-410 Safety profiles of Fe2+ and Fe3+ oral preparations in the treatment of iron deficiency anemia in children. Kavakli K, Yilmaz D, Cetinkaya B, Balkan C, Sözmen EY, Sağin FG

The major purpose of this study was to compare the oxidant-related toxicities of the different oral iron preparations in children with iron deficiency anemia (IDA); the second aim was to investigate the side effects of iron preparations. Seventy-two children with IDA were randomly included in the Fe(2+) group (n = 39) or the Fe(3+) group (n = 33). Some oxidizable substrates (erythrocytes malondialdehyde (MDA), urine 8-isoprostane, and basal and Cu-stimulated-oxidized LDL and antioxidant enzyme (... Abstract

Cited 12 times since 2004 (0.6 per year) source: EuropePMC

European journal of pharmacology, Volume 493, Issue 1-3, 1 1 2004, Pages 161-165 Angiotensin deficiency in mice leads to dilated cardiomyopathy. Walther T, Steendijk P, Westermann D, Hohmann C, Schulze K, Heringer-Walther S, Schultheiss HP, Tschöpe C

To explore the role of angiotensin II, we assessed hemodynamics and cardiac function in angiotensinogen-deficient mice in comparison to wild-type animals. Left ventricular end-diastolic diameter and wall thickness were evaluated by echocardiography and systolic and diastolic left ventricular function by pressure-volume relations using a micro-conductance catheter. Compared to wild-type animals, the angiotensinogen-deficient mice were hypotensive and showed impaired systolic function. The hearts... Abstract

Cited 31 times since 2004 (1.5 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 90, Issue 6, 1 1 2004, Pages 678-684 Cardiovascular response to physical exercise in adult patients after atrial correction for transposition of the great arteries assessed with magnetic resonance imaging. Roest AA, Lamb HJ, van der Wall EE, Vliegen HW, van den Aardweg JG, Kunz P, de Roos A, Helbing WA

Objective: To assess with magnetic resonance imaging (MRI) cardiovascular function in response to exercise in patients after atrial correction of transposition of the great arteries (TGA). Methods: Cardiac function at rest and during submaximal exercise was assessed with MRI in 27 patients with TGA (mean (SD) age 26 (5) years) late (23 (2) years) after atrial correction and in 14 control participants (25 (5) years old). Results: At rest, only right ventricular ejection fraction was significantly... Abstract

Cited 46 times since 2004 (2.2 per year) source: EuropePMC

The American journal of cardiology, Volume 93, Issue 12, 1 1 2004, Pages 1461-1464 Head-to-head comparison between contrast-enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in men with ischemic cardiomyopathy. Kaandorp TA, Bax JJ, Schuijf JD, Viergever EP, van Der Wall EE, de Roos A, Lamb HJ

Contrast-enhanced magnetic resonance imaging (MRI) can predict functional recovery after revascularization. Segments with small, subendocardial scars have a large likelihood of recovery, and segments with transmural infarction have a small likelihood of recovery. Segments with an intermediate extent of infarction have an intermediate likelihood of recovery, and therefore, additional information is needed. Accordingly, the transmurality of infarction on contrast-enhanced MRI was compared with low... Abstract