Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6173 results
Cited 9 times since 1998 (0.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 65, Issue 6, 1 1 1998, Pages 1726-1729 Pulmonary root replacement with the Freestyle stentless aortic xenograft in growing pigs. Schoof PH, Hazekamp MG, van Krieken HH, Huysmans HA
Background: The stentless xenograft with its favorable hemodynamic performance on the left side of the heart seems an attractive, readily available alternative for the reconstruction of the right ventricular outflow tract in children. Methods: To assess its function in a preclinical animal investigation, we replaced the pulmonary root with a Freestyle stentless aortic xenograft in 18 piglets of 26.6 +/- 3.2 kg weight. The animals were allowed to grow as much as possible and slaughtered when symp... Abstract
Cited 4 times since 1998 (0.1 per year) source: EuropePMC
Acta paediatrica (Oslo, Norway : 1992), Volume 87, Issue 5, 1 1 1998, Pages 605-606 Serum malondialdehyde levels in preterm and fullterm infants undergoing phototherapy. Akisü M, Coker C, Tüzün S, Yilmaz D, Kültürsay N
Cited 36 times since 1998 (1.3 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 18, Issue 5, 1 1 1998, Pages 693-701 Binding of human urokinase-type plasminogen activator to its receptor: residues involved in species specificity and binding. Quax PH, Grimbergen JM, Lansink M, Bakker AH, Blatter MC, Belin D, van Hinsbergh VW, Verheijen JH
Urokinase-type plasminogen activator (UPA), particularly when bound to its receptor (UPAR), is thought to play a major role in local proteolytic processes, thus facilitating cell migration as may occur during angiogenesis, neointima and atherosclerotic plaque formation, and tumor cell invasion. To facilitate understanding of the need and function of the UPA/UPAR interaction in cell migration and vascular remodeling, we changed several amino acid residues in UPA so as to interfere with its intera... Abstract
Cited 8 times since 1998 (0.3 per year) source: EuropePMC
Cardiovascular drugs and therapy, Volume 12 Suppl 1, 1 1 1998, Pages 111-118 Proposed synergistic effect of calcium channel blockers with lipid-lowering therapy in retarding progression of coronary atherosclerosis. Jukema JW, van Boven AJ, Zwinderman AH, Van der Laarse A, Bruschke AV
Lipid-lowering therapy now has undoubtedly proven to be an effective therapeutic modality to retard the progression of coronary atherosclerosis. An additional approach for prevention of the progression of atherosclerosis is calcium channel blocker (CCB) treatment. Evidence indicating that CCBs inhibit atherosclerosis is less unequivocal than the clear evidence for lipid-lowering therapy. Many investigations support the view that a number of key processes in atherosclerosis may be influenced by C... Abstract
Cited 39 times since 1998 (1.4 per year) source: EuropePMC
American heart journal, Volume 135, Issue 4, 1 1 1998, Pages 571-576 Depressed heart rate variability is associated with events in patients with stable coronary artery disease and preserved left ventricular function. REGRESS Study Group. van Boven AJ, Jukema JW, Haaksma J, Zwinderman AH, Crijns HJ, Lie KI
Background: Little is known about the value of heart rate variability in patients with symptomatic coronary artery disease with a preserved left ventricular function. We hypothesized that in these patients heart rate variability might be a helpful adjunct to conventional parameters to predict clinical events. Methods: In a prospective 2-year follow-up study ambulatory electrocardiographic recordings were performed in 263 consecutive male patients (mean age 56+/-8 years) with stable angina pector... Abstract
Cited 1 times since 1998 (0 per year) source: EuropePMC
The Turkish journal of pediatrics, Volume 40, Issue 2, 1 1 1998, Pages 279-281 Subcutaneous granuloma annulare and IgA-IgG2 deficiency. Kütükçüler N, Tütüncüoğlu S, Yilmaz D, Akalin T, Kandiloğlu G
Subcutaneous granuloma annulare (SGA) is a benign granulomatous disease occurring in childhood, with lesions most commonly located about the elbow, knee and scalp. the etiology of SGA remains obscure. We present a typical case with SGA also showing laboratory findings of IgA and IgG2 deficiency. Histologic findings of the lesions on the scalp were characterized by multiple large foci of complete collagen degeneration with a peripheral pallsade of histiocytes; the foci of degeneration was edemato... Abstract
Cited 6 times since 1998 (0.2 per year) source: EuropePMC
International journal of cardiac imaging, Volume 14, Issue 2, 1 1 1998, Pages 123-126 Embolization as a treatment of life-threatening haemoptysis in an adult with Tetralogy of Fallot with pulmonary atresia. van der Weijden P, Baur LH, Kool LJ, Vliegen HW, van der Wall EE
Aim: Description of embolization as a treatment for bleeding bronchopulmonary collaterals in congenital heart disease. Methods: After palliative corrective surgery of Tetralogy of Fallot with pulmonary atresia, haemoptysis due to ruptured bronchopulmonary collaterals is a well known complication. We describe a 31 year old patient with haemoptysis after incomplete correction because of Tetralogy of Fallot with pulmonary atresia. Because supportive treatment failed, the bleeding site was localized... Abstract
Cited 5 times since 1998 (0.2 per year) source: EuropePMC
Pediatric research, Volume 43, Issue 3, 1 1 1998, Pages 331-337 Contribution of synchronized atrial systole to left ventricular contraction in the newborn pig heart. Klautz RJ, Baan J, Teitel DF
Synchronized atrial contraction may be much more important in the newborn, who has a faster heart rate and a less compliant ventricle, than in the adult. We therefore investigated the extent by which synchronized atrioventricular contraction contributes to cardiac output and cardiac work in a neonatal circulation, and whether this effect can be fully explained by the Starling mechanism. In neonatal piglets, left ventricular pressure and volume (conductance catheter) were measured during atrial a... Abstract
Cited 13 times since 1998 (0.5 per year) source: EuropePMC
Vision research, Volume 38, Issue 5, 1 1 1998, Pages 659-668 Stereoscopic segregation of transparent surfaces and the effect of motion contrast. Lankheet MJ, Palmen M
Stereoscopic segregation in depth was studied using two superimposed frontoparallel surfaces displayed in dynamic random dot stereograms. The two patterns were positioned symmetrically in front of and behind a binocular fixation point. They were either stationary, or they could move relative to each other. Sensitivity for segregation was established by adding gaussian distributed disparity noise to the disparities specifying the two planes, and finding the noise amplitude that gave threshold seg... Abstract
Cited 71 times since 1998 (2.6 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 18, Issue 2, 1 1 1998, Pages 265-271 -455G/A polymorphism of the beta-fibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men: proposed role for an acute-phase reaction pattern of fibrinogen. REGRESS group. de Maat MP, Kastelein JJ, Jukema JW, Zwinderman AH, Jansen H, Groenemeier B, Bruschke AV, Kluft C
Increased plasma fibrinogen levels have been identified as a risk indicator for myocardial infarction, stroke, and thrombosis. Both environmental and genetic factors make an important contribution to plasma fibrinogen levels in humans. In the present study we evaluated, in patients with serum cholesterol levels between 4 and 8 mmol/L, the relation of plasma levels and polymorphisms of fibrinogen with coronary artery disease (CAD), cross-sectionally at baseline and after a 2-year follow-up period... Abstract
Cited 11 times since 1998 (0.4 per year) source: EuropePMC
The American journal of cardiology, Volume 81, Issue 3, 1 1 1998, Pages 302-305 Subcutaneous single-incision implantation of cardioverter-defibrillators under local anesthesia by electrophysiologists in the electrophysiology laboratory. van Rugge FP, Savalle LH, Schalij MJ
Implantable cardioverter-defibrillators (ICDs) have traditionally been implanted at the operating room under general anesthesia. Endocardial lead systems and downsized devices allowed implantation by electrophysiologists in the pectoral region. The present study evaluates the safety and efficacy of subcutaneous ICD implantation performed entirely by electrophysiologists using a single-incision approach for lead insertion and device placement under local anesthesia. Between June 1996 and May 1997... Abstract
Cited 103 times since 1998 (3.8 per year) source: EuropePMC
Circulation, Volume 97, Issue 7, 1 1 1998, Pages 666-672 Functional and metabolic evaluation of the athlete's heart by magnetic resonance imaging and dobutamine stress magnetic resonance spectroscopy. Pluim BM, Lamb HJ, Kayser HW, Leujes F, Beyerbacht HP, Zwinderman AH, van der Laarse A, Vliegen HW, de Roos A, van der Wall EE
Background: The question of whether training-induced left ventricular hypertrophy in athletes is a physiological rather than a pathophysiological phenomenon remains unresolved. The purpose of the present study was to detect any abnormalities in cardiac function in hypertrophic hearts of elite cyclists and to examine the response of myocardial high-energy phosphate metabolism to high workloads induced by atropine-dobutamine stress. Methods and results: We studied 21 elite cyclists and 12 healthy... Abstract
Cited 34 times since 1998 (1.2 per year) source: EuropePMC
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, Volume 147, 1 1 1998, Pages 107-119 Isolated hepatic perfusion with tumor necrosis factor alpha and melphalan: experimental studies in pigs and phase I data from humans. de Vries MR, Borel Rinkes IH, van de Velde CJ, Wiggers T, Tollenaar RA, Kuppen PJ, Vahrmeijer AL, Eggermont AM
We report our experience with isolated hepatic perfusion (IHP) with tumor necrosis factor (TNF) and melphalan in an experimental pig study and of a phase I study in humans. IHP was performed with inflow catheters in the hepatic artery and portal vein and an outflow catheter in eh caval vein. An extracorporeal venovenous bypass was used. IHP consisted of a 60-min perfusion with hyperthermia (> 41 degrees C). For the pig protocol rhTNF alpha 50 micrograms/kg alone (n = 5) or rhTNF alpha 50 micr... Abstract
Cited 34 times since 1998 (1.2 per year) source: EuropePMC
Clinical genetics, Volume 53, Issue 1, 1 1 1998, Pages 27-33 The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group. Kastelein JJ, Groenemeyer BE, Hallman DM, Henderson H, Reymer PW, Gagné SE, Jansen H, Seidell JC, Kromhout D, Jukema JW, Bruschke AV, Boerwinkle E, Hayden MR
Two mutations in the lipoprotein lipase (LPL) gene, a T to G transition at position -93 of the proximal promoter region and an Asp9Asn substitution in exon 2, were examined in 762 Dutch males with angiographically-diagnosed coronary artery disease (CAD) and 296 healthy normolipidemic Dutch males. The two mutations exhibited strong linkage disequilibrium (D' = 0.975). A significantly higher proportion of cases (4.86%) than controls (1.37%) carried the -93G/Asn9 allele (p = 0.008). In the com... Abstract
Cited 5 times since 1998 (0.2 per year) source: EuropePMC
The American journal of cardiology, Volume 81, Issue 2, 1 1 1998, Pages 152-157 Clinical and angiographic outcome of Micro Stent II implantation in native coronary arteries. Oemrawsingh PV, Tuinenburg JC, Schalij MJ, Jukema JW, Reiber JH, Bruschke AV
To evaluate immediate success and 6-month restenosis rate, 70 Micro Stents II were implanted for 65 stenoses in 63 patients (age 59+/-9 years). Stable angina pectoris was present in 47% of the patients (38% class I to III; 9% class IV), whereas 32% had postinfarction angina and 21% had unstable angina. Indications for stent implantation were elective in 62% and semi-elective in 38% of the patients. Sixty-two percent of the patients received ticlopidin and acetylsalicylic acid for 28 days, wherea... Abstract
Cited 373 times since 1998 (13.7 per year) source: EuropePMC
The New England journal of medicine, Volume 338, Issue 2, 1 1 1998, Pages 86-93 The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group. Kuivenhoven JA, Jukema JW, Zwinderman AH, de Knijff P, McPherson R, Bruschke AV, Lie KI, Kastelein JJ
Background: The high-density lipoprotein (HDL) cholesterol concentration is inversely related to the risk of coronary artery disease. The cholesteryl ester transfer protein (CETP) has a central role in the metabolism of this lipoprotein and may therefore alter the susceptibility to atherosclerosis. Methods: The DNA of 807 men with angiographically documented coronary atherosclerosis was analyzed for the presence of a polymorphism in the gene coding for CETP. The presence of this DNA variation wa... Abstract
Cited 9 times since 1998 (0.3 per year) source: EuropePMC
Catheterization and cardiovascular diagnosis, Volume 43, Issue 1, 1 1 1998, Pages 19-27; discussion 28 Micro stent I, initial results, and six months follow-up by quantitative coronary angiography. Schalij MJ, Savalle LH, Tresukosol D, Jukema JW, Reiber JH, Bruschke AV
The Micro stent (MS) is a balloon expandable stent that allows the treatment of stenoses in distal and tortuous coronary arteries. This prospective study was performed to evaluate initial and late results of MS implantations. A total of 127 MS (101 in native coronary arteries and 26 in saphenous vein grafts) were implanted in 85 patients (1.5 stents/pt, 65 male, and 20 female, age 62, +/-10 yr) with angina pectoris class II-III: 21 (25%), angina pectoris class IV: 41(48%), and acute myocardial i... Abstract
Cited 36 times since 1998 (1.3 per year) source: EuropePMC
Journal of virology, Volume 72, Issue 1, 1 1 1998, Pages 862-867 Identification of the leader-body junctions for the viral subgenomic mRNAs and organization of the simian hemorrhagic fever virus genome: evidence for gene duplication during arterivirus evolution. Godeny EK, de Vries AA, Wang XC, Smith SL, de Groot RJ
Simian hemorrhagic fever virus (SHFV) was recently reclassified and assigned to the new virus family Arteriviridae. During replication, arteriviruses produce a 3' coterminal, nested set of subgenomic mRNAs (sgRNAs). These sgRNAs arise by discontinuous transcription, and each contains a 5' leader sequence which is joined to the body of the mRNA through a conserved junction sequence. Only the 5'-most open reading frame (ORF) is believed to be transcribed from each sgRNA. The SHFV ge... Abstract
Cited 15 times since 1998 (0.5 per year) source: EuropePMC
Magnetic resonance imaging, Volume 16, Issue 2, 1 1 1998, Pages 137-145 A new diagnostic approach to vascular rings and pulmonary slings: the role of MRI. Beekman RP, Hazekamp MG, Sobotka MA, Meijboom EJ, de Roos A, Staalman CR, Beek FJ, Ottenkamp J
Unlabelled: The conventional diagnostic work-up of a patient suspected of having a vascular cause for stridor, or dysphagia, includes esophagography and bronchoscopy to delineate the abnormal structure without imaging the structure itself. Cine-angiography is regarded as the golden standard, but is not routinely performed. Magnetic resonance imaging (MRI) is non-invasive and has the important advantage over cine-angiography of depicting all structures in the field of view. Color Doppler echocard... Abstract
Statistics in medicine, Volume 16, Issue 24, 1 1 1997, Pages 2829-2841 On the statistical modelling of coronary arteriographic data: dynamics of coronary atherosclerosis related to systemic and focal parameters. REGRESS Study Group. Regression Growth Evaluation Statin Study. Zwinderman AH, Jukema JW, van Boven AJ, Reiber JH
Existing methods to analyse data from repeated arteriographic progression/regression studies are restrictive and do not fully explore the dynamics of coronary artherosclerosis. We present a new approach making a distinction between new occlusions, new lesions, and growth of existing lesions. Random effect models, based on the logistic, the Poisson, and the normal distribution are proposed with correlation depending on distance. The data from the Regression Growth Evaluation Statin Study (REGRESS... Abstract