6128 results
Cited 11 times since 2021 (3.1 per year)
source: EuropePMC
Scientific reports,
Volume 11, Issue 1, 24 4 2021, Pages 17121
Differential progression of coronary atherosclerosis according to plaque composition: a cluster analysis of PARADIGM registry data.
Yoon YE, Baskaran L, Lee BC, Pandey MK, Goebel B, Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Narula J, Bax JJ, Lin FY, Shaw L, Chang HJ
Patient-specific phenotyping of coronary atherosclerosis would facilitate personalized risk assessment and preventive treatment. We explored whether unsupervised cluster analysis can categorize patients with coronary atherosclerosis according to their plaque composition, and determined how these differing plaque composition profiles impact plaque progression. Patients with coronary atherosclerotic plaque (n = 947; median age, 62 years; 59% male) were enrolled from a prospective multi-national re...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Frontiers in physiology,
Volume 12, 23 4 2021, Pages 710020
The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes.
Ördög B, Teplenin A, De Coster T, Bart CI, Dekker SO, Zhang J, Ypey DL, de Vries AAF, Pijnappels DA
Aim: Channelrhodopsins (ChRs) are a large family of light-gated ion channels with distinct properties, which is of great importance in the selection of a ChR variant for a given application. However, data to guide such selection for cardiac optogenetic applications are lacking. Therefore, we investigated the functioning of different ChR variants in normal and pathological hypertrophic cardiomyocytes subjected to various illumination protocols. Methods and Results: Isolated neonatal rat ventricul...
Abstract
Cited 12 times since 2021 (3.4 per year)
source: EuropePMC
European journal of heart failure,
Volume 23, Issue 10, 22 4 2021, Pages 1597-1609
Guidance on the management of left ventricular assist device (LVAD) supported patients for the non-LVAD specialist healthcare provider: executive summary.
Ben Gal T, Ben Avraham B, Milicic D, Crespo-Leiro MG, Coats AJS, Rosano G, Seferovic P, Ruschitzka F, Metra M, Anker S, Filippatos G, Altenberger J, Adamopoulos S, Barac YD, Chioncel O, de Jonge N, Elliston J, Frigerio M, Goncalvesova E, Gotsman I, Grupper A, Hamdan R, Hammer Y, Hasin T, Hill L, Itzhaki Ben Zadok O, Abuhazira M, Lavee J, Mullens W, Nalbantgil S, Piepoli MF, Ponikowski P, Potena L, Ristic A, Ruhparwar A, Shaul A, Tops LF, Tsui S, Winnik S, Jaarsma T, Gustafsson F
The accepted use of left ventricular assist device (LVAD) technology as a good alternative for the treatment of patients with advanced heart failure together with the improved survival of patients on the device and the scarcity of donor hearts has significantly increased the population of LVAD supported patients. Device-related, and patient-device interaction complications impose a significant burden on the medical system exceeding the capacity of LVAD implanting centres. The probability of an L...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
JTCVS open,
Volume 8, 21 3 2021, Pages 668-676
Incidence and risk factors of unplanned emergency department visits following thoracic surgery.
Hazewinkel MHJ, Berendsen RR, van Klink RCJ, Dik H, Wink J, Braun J, de Lind van Wijngaarden RAF
Background: Unplanned visits for care following a surgical procedure can represent a lapse in quality of care. The purpose of this study was to define the proportion of patients undergoing thoracic surgery who return to the emergency department (ED) within 6 months after discharge and the reasons for the returns. In addition, the risk factors for ED visits after thoracic surgery were identified. Methods: All adult patients undergoing thoracic surgery at the Leiden University Medical Center betwe...
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
International journal of cardiology. Heart & vasculature,
Volume 36, 20 3 2021, Pages 100858
Referral and participation in cardiac rehabilitation of patients following acute coronary syndrome; lessons learned.
Rodrigo SF, Van Exel HJ, Van Keulen N, Van Winden L, Beeres SLMA, Schalij MJ
Purpose: Cardiac rehabilitation (CR) after hospitalization for acute coronary syndrome (ACS) has shown to reduce mortality, readmissions, and improve quality of life. CR is recommended by international guidelines but previous studies have shown low participation rates. Systematic CR referral might improve CR participation. Methods: The present study evaluates CR referral and CR participation of patients hospitalized for ACS in 2017 and treated according to local protocol, which includes systemat...
Abstract
Cited 13 times since 2021 (3.7 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 12, 18 3 2021, Pages 2429-2440
Association of Tube Voltage With Plaque Composition on Coronary CT Angiography: Results From PARADIGM Registry.
Takagi H, Leipsic JA, Indraratna P, Gulsin G, Khasanova E, Tzimas G, Lin FY, Shaw LJ, Lee SE, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Maffei E, Pontone G, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Bax JJ, Chang HJ
Objectives: This study sought to investigate the impact of low tube voltage scanning heterogeneity of coronary luminal attenuation on plaque quantification and characterization with coronary computed tomography angiography (CCTA). Background: The impact of low tube voltage and coronary luminal attenuation on quantitative coronary plaque remains uncertain. Methods: A total of 1,236 consecutive patients (age: 60 ± 9 years; 41% female) who underwent serial CCTA at an interval of ≥2 years were inclu...
Abstract
Cited 4 times since 2021 (1.1 per year)
source: EuropePMC
Frontiers in immunology,
Volume 12, 18 3 2021, Pages 676662
Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies.
Loeven MA, Maciej-Hulme ML, Yanginlar C, Hubers MC, Kellenbach E, de Graaf M, van Kuppevelt TH, Wetzels J, Rabelink TJ, Smith RJH, van der Vlag J
Complement dysregulation is characteristic of the renal diseases atypical hemolytic uremic syndrome (aHUS) and complement component 3 glomerulopathy (C3G). Complement regulatory protein Factor H (FH) inhibits complement activity, whereas FH-related proteins (FHRs) lack a complement regulatory domain. FH and FHRs compete for binding to host cell glycans, in particular heparan sulfates (HS). HS is a glycosaminoglycan with an immense structural variability, where distinct sulfation patterns mediate...
Abstract
European heart journal. Case reports,
Volume 5, Issue 9, 17 3 2021, Pages ytab335
Fusion cardiac resynchronization therapy in an left ventricular assist device patient from two devices and crossing leads: a case report.
Egorova AD, van Erven L, Beeres SLMA, Tops LF
Background: Cardiac implanted electronic devices (CIED) have significantly improved the survival and quality of life in heart failure patients. Although implantable cardioverter-defibrillators (ICD) and cardiac resynchronization therapy (CRT) have a major role in patients with moderate to severe heart failure symptoms, the role of these devices in patients with a left ventricular assist device (LVAD) is not yet well defined. The burden of CIED-related procedures in patients with an LVAD is high....
Abstract
Cited 11 times since 2021 (3.1 per year)
source: EuropePMC
Thrombosis research,
Volume 206, 17 3 2021, Pages 66-75
Efficacy and safety of a 12-week outpatient pulmonary rehabilitation program in Post-PE Syndrome.
Boon GJAM, Janssen SMJ, Barco S, Bogaard HJ, Ghanima W, Kroft LJM, Meijboom LJ, Ninaber MK, Nossent EJ, Spruit MA, Symersky P, Vliegen HW, Noordegraaf AV, Huisman MV, Siegerink B, Abbink JJ, Klok FA
Background: The Post-Pulmonary Embolism Syndrome (PPES) comprises heterogeneous entities, including chronic thromboembolic disease with/without pulmonary hypertension (CTEPH/CTEPD), and deconditioning. Objectives: To assess underlying physiological determinants of PPES, and efficacy and safety of rehabilitation training in these patients. Methods: 56 consecutive PE patients with persistent dyspnea and/or functional limitations despite ≥3 months of anticoagulation underwent standardized diagnosti...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 8, 16 3 2021, Pages e009808
Lesion Size and Lesion Maturation After Radiofrequency Catheter Ablation for Ventricular Tachycardia in Humans With Nonischemic Cardiomyopathy.
Glashan CA, Stevenson W, Zeppenfeld K
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 14, Issue 8, 12 2 2021, Pages e012612
Hemodynamic Consequences of an Undersized Extracardiac Conduit in an Adult Fontan Patient Revealed by 4-Dimensional Flow Magnetic Resonance Imaging.
Rijnberg FM, van Assen HC, Hazekamp MG, Roest AAW, Westenberg JJM
Abstract
Cited 13 times since 2021 (3.7 per year)
source: EuropePMC
American journal of physiology. Lung cellular and molecular physiology,
Volume 321, Issue 4, 11 2 2021, Pages L775-L786
Disease modeling following organoid-based expansion of airway epithelial cells.
Eenjes E, van Riet S, Kroon AA, Slats AM, Khedoe PPSJ, Boerema-de Munck A, Buscop-van Kempen M, Ninaber DK, Reiss IKM, Clevers H, Rottier RJ, Hiemstra PS
Air-liquid interface (ALI) cultures are frequently used in lung research but require substantial cell numbers that cannot readily be obtained from patients. We explored whether organoid expansion [three-dimensional (3D)] can be used to establish ALI cultures from clinical samples with low epithelial cell numbers. Airway epithelial cells were obtained from tracheal aspirates (TA) from preterm newborns and from bronchoalveolar lavage (BAL) or bronchial tissue (BT) from adults. TA and BAL cells wer...
Abstract
Cited 8 times since 2021 (2.2 per year)
source: EuropePMC
European heart journal open,
Volume 1, Issue 2, 9 2 2021, Pages oeab018
Segmental assessment of blood flow efficiency in the total cavopulmonary connection using four-dimensional flow magnetic resonance imaging: vortical flow is associated with increased viscous energy loss rate.
Rijnberg FM, Juffermans JF, Hazekamp MG, Helbing WA, Lamb HJ, Roest AAW, Westenberg JJM, van Assen HC
Aims: To study flow-related energetics in multiple anatomical segments of the total cavopulmonary connection (TCPC) in Fontan patients from four-dimensional (4D) flow magnetic resonance imaging (MRI), and to study the relationship between adverse flow patterns and segment-specific energetics. Methods and results: Twenty-six extracardiac Fontan patients underwent 4D flow MRI of the TCPC. A segmentation of the TCPC was automatically divided into five anatomical segments [conduit, superior vena cav...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
International journal of cardiology,
Volume 341, 8 2 2021, Pages 31-38
Determinants of exercise limitation in contemporary paediatric Fontan patients with an extra cardiac conduit.
Harteveld LM, Blom NA, Terol Espinosa de Los Monteros C, van Dijk JG, Kuipers IM, Rammeloo LAJ, de Geus EJC, Hazekamp MG, Ten Harkel ADJ
Background: Although various determinants of exercise limitation in Fontan patients have been studied, most research has been performed in patients who underwent different surgical procedures with differing haemodynamic characteristics. The aim of the current study was to evaluate non-invasively measured cardiovascular parameters and their influence on exercise performance in paediatric Fontan patients with an extracardiac conduit and moderate-good systolic ventricular function. Methods: Fontan...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 5, 6 1 2021, Pages 3539-3546
Sex differences in prognosis of significant secondary mitral regurgitation.
Namazi F, van der Bijl P, Vo NM, van Wijngaarden SE, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Secondary mitral regurgitation (MR) is more frequent in men than in women. However, little is known about differences in prognosis between men and women with secondary MR. The objective of this study is to investigate the sex distribution of secondary MR and the prognostic differences between sexes. Methods: Patients with significant secondary MR, of both ischaemic and non-ischaemic aetiologies, were identified through the departmental electronic patient files and retrospectively analysed....
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 157, 6 1 2021, Pages 15-21
Changes in Global Left Ventricular Myocardial Work Indices and Stunning Detection 3 Months After ST-Segment Elevation Myocardial Infarction.
Lustosa RP, Fortuni F, van der Bijl P, Mahdiui ME, Montero-Cabezas JM, Kostyukevich MV, Knuuti J, Marsan NA, Delgado V, Bax JJ
Global left ventricular (LV) myocardial work (MW) indices (GLVMWI) are derived from speckle tracking echocardiographic strain data in combination with non-invasive blood pressure measurements. Changes in global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE) after ST-segment elevation myocardial infarction (STEMI) have not been explored. The aim of present study was to assess the evolution of GLVMWI in STEMI patients from baseline (inde...
Abstract
Cited 27 times since 2021 (7.6 per year)
source: EuropePMC
The European respiratory journal,
Volume 58, Issue 2, 5 1 2021, Pages 2100636
Home monitoring reduced short stay admissions in suspected COVID-19 patients: COVID-box project.
Dirikgil E, Roos R, Groeneveld GH, Heringhaus C, Silven AV, Petrus AHJ, Villalobos-Quesada M, Tsonaka R, van der Boog PJM, Rabelink TJ, Bos WJW, Chavannes NH, Atsma DE, Teng YKO
Abstract
JTCVS open,
Volume 8, 5 1 2021, Pages 300
Reply from authors: Many roads lead to Rome.
Wijngaarden AL, Tomšič A, Marsan NA, Palmen M
Abstract
Cited 13 times since 2021 (3.6 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 5 1 2021, Pages 683849
The Influence of Respiration on Blood Flow in the Fontan Circulation: Insights for Imaging-Based Clinical Evaluation of the Total Cavopulmonary Connection.
van der Woude SFS, Rijnberg FM, Hazekamp MG, Jongbloed MRM, Kenjeres S, Lamb HJ, Westenberg JJM, Roest AAW, Wentzel JJ
Congenital heart disease is the most common birth defect and functionally univentricular heart defects represent the most severe end of this spectrum. The Fontan circulation provides an unique solution for single ventricle patients, by connecting both caval veins directly to the pulmonary arteries. As a result, the pulmonary circulation in Fontan palliated patients is characterized by a passive, low-energy circulation that depends on increased systemic venous pressure to drive blood toward the l...
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
Cardiology in the young,
Volume 32, Issue 5, 5 1 2021, Pages 794-799
Acute kidney injury after the arterial switch operation: incidence, risk factors, and outcomes.
Schoenmaker NJ, Weeda JA, van der Palen RLF, Hazekamp MG, Bunker-Wiersma HE
Background: The aim of this retrospective cohort study was to determine the incidence, potential risk factors, characteristics, and outcomes of acute kidney injury in children following the arterial switch operation for transposition of the great arteries. Methods: Retrospective review of children who underwent ASO between 2000 and 2020 in our tertiary children's hospital in the Netherlands. Pre-and post-ASO serum creatinine levels were collected. Severe AKI was defined as 100% serum creati...
Abstract
