Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7365 results
Cited 32 times since 2021 (7 per year) source: EuropePMC
ESC heart failure, Volume 8, Issue 4, 2 1 2021, Pages 2968-2981 Predictors and prognosis of right ventricular function in pulmonary hypertension due to heart failure with reduced ejection fraction. Schmeißer A, Rauwolf T, Groscheck T, Fischbach K, Kropf S, Luani B, Tanev I, Hansen M, Meißler S, Schäfer K, Steendijk P, Braun-Dullaeus RC
Aims: Failure of right ventricular (RV) function worsens outcome in pulmonary hypertension (PH). The adaptation of RV contractility to afterload, the RV-pulmonary artery (PA) coupling, is defined by the ratio of RV end-systolic to PA elastances (Ees/Ea). Using pressure-volume loop (PV-L) technique we aimed to identify an Ees/Ea cut-off predictive for overall survival and to assess hemodynamic and morphologic conditions for adapted RV function in secondary PH due to heart failure with reduced eje... Abstract
Cited 13 times since 2021 (2.9 per year) source: EuropePMC
European heart journal, Volume 42, Issue 19, 1 1 2021, Pages 1912-1925 Multimodality imaging in valvular heart disease: how to use state-of-the-art technology in daily practice. Reid A, Blanke P, Bax JJ, Leipsic J
Our understanding of the complexities of valvular heart disease (VHD) has evolved in recent years, primarily because of the increased use of multimodality imaging (MMI). Whilst echocardiography remains the primary imaging technique, the contemporary evaluation of patients with VHD requires comprehensive analysis of the mechanism of valvular dysfunction, accurate quantification of severity, and active exclusion extravalvular consequences. Furthermore, advances in surgical and percutaneous therapi... Abstract
Cited 499 times since 2021 (109.6 per year) source: EuropePMC
European heart journal, Volume 42, Issue 19, 1 1 2021, Pages 1825-1857 Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research. VARC-3 WRITING COMMITTEE, Généreux P, Piazza N, Alu MC, Nazif T, Hahn RT, Pibarot P, Bax JJ, Leipsic JA, Blanke P, Blackstone EH, Finn MT, Kapadia S, Linke A, Mack MJ, Makkar R, Mehran R, Popma JJ, Reardon M, Rodes-Cabau J, Van Mieghem NM, Webb JG, Cohen DJ, Leon MB
Aims: The Valve Academic Research Consortium (VARC), founded in 2010, was intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these endpoints for transcatheter and surgical aortic valve clinical trials. Rapid evolution of the field, including the emergence of new complications, expanding clinical indications, and novel therapy strategies have mandated further refinement and expansion of these definitions to ensure clinical relevance. This document provides... Abstract
Cited 34 times since 2021 (7.5 per year) source: EuropePMC
European journal of preventive cardiology, Volume 28, Issue 6, 1 1 2021, Pages 611-621 Anticoagulation in patients with atrial fibrillation and active cancer: an international survey on patient management. Boriani G, Lee G, Parrini I, Lopez-Fernandez T, Lyon AR, Suter T, Van der Meer P, Cardinale D, Lancellotti P, Zamorano JL, Bax JJ, Asteggiano R, Council of Cardio-Oncology of the European Society of Cardiology
Background: In patients with active cancer and atrial fibrillation (AF) anticoagulation, thrombotic and bleeding risk still entail uncertainty. Aim: We explored the results of an international survey examining the knowledge and behaviours of a large group of physicians. Methods and results: A web-based survey was completed by 960 physicians (82.4% cardiologists, 75.5% from Europe). Among the currently available anticoagulants for stroke prevention in patients with active cancer, direct oral anti... Abstract
Cited 4 times since 2021 (0.9 per year) source: EuropePMC
The Journal of antimicrobial chemotherapy, Volume 76, Issue 6, 1 1 2021, Pages 1604-1613 National point prevalence study on carriage of multidrug-resistant microorganisms in Dutch long-term care facilities in 2018. van Kleef E, Wielders CCH, Schouls LM, Feenstra SG, Hertogh CMPM, Bonten MJM, van Weert Y, Tostmann A, van der Lubben M, de Greeff SC, PPO study group
Objectives: Long-term care facilities (LTCFs) may act as a reservoir of ESBL-producing Enterobacterales (ESBL-E) and carbapenemase-producing Enterobacterales (CPE) for hospitals and the general population. In this study, we estimated the prevalence and molecular epidemiology of rectal carriage with ESBL-E and CPE in residents of Dutch LTCFs between March 2018 and December 2018. Methods: LTCFs were geographically selected across the country. For each LTCF, a random sample of residents were tested... Abstract
Cited 5 times since 2021 (1.1 per year) source: EuropePMC
RMD open, Volume 7, Issue 2, 1 1 2021, Pages e001524 New risk model is able to identify patients with a low risk of progression in systemic sclerosis. van Leeuwen NM, Maurits M, Liem S, Ciaffi J, Ajmone Marsan N, Ninaber M, Allaart C, Gillet van Dongen H, Goekoop R, Huizinga T, Knevel R, De Vries-Bouwstra J
Objectives: To develop a prediction model to guide annual assessment of systemic sclerosis (SSc) patients tailored in accordance to disease activity. Methods: A machine learning approach was used to develop a model that can identify patients without disease progression. SSc patients included in the prospective Leiden SSc cohort and fulfilling the ACR/EULAR 2013 criteria were included. Disease progression was defined as progression in ≥1 organ system, and/or start of immunosuppression or death. U... Abstract
Cited 1 times since 2021 (0.2 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 32, Issue 5, 1 1 2021, Pages 834-836 Repair of traumatic avulsion of the right bronchus in children using extracorporeal membrane oxygenation support. Ricciardi G, Putman LM, Hazekamp MG
Traumatic avulsion of the right main bronchus in children is usually caused by blunt trauma or traffic accidents. Primary repair by suturing is the preferred treatment. Lesions are life threatening and urgent or emergency surgical repair is indicated. We report our experience with 2 cases of traumatic avulsion of right bronchus in children successfully suture repaired with the use of extracorporeal membrane oxygenation. Abstract
Cited 44 times since 2021 (9.7 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 59, Issue 5, 1 1 2021, Pages 968-977 Long-term outcome after the arterial switch operation: 43 years of experience. van der Palen RLF, Blom NA, Kuipers IM, Rammeloo LAJ, Jongbloed MRM, Konings TC, Bouma BJ, Koolbergen DR, Hazekamp MG
Objectives: The objective of this study was to assess our 43-year experience with arterial switch operation (ASO) for transposition of the great arteries (TGA) by analysing cardiac outcome measures (hospital and late mortality, reoperations and catheter interventions, significant coronary artery obstruction) and to identify risk factors for reoperation and catheter interventions. Methods: A total of 490 patients who underwent ASO for TGA from 1977 to 2020 were included in this retrospective, sin... Abstract
European heart journal, Volume 42, Issue 18, 1 1 2021, Pages 1811 A case of tortuous anatomy: cervical aortic arch. van Driest FY, Stöger JL, Scholte AJHA, Jukema JW, Egorova AD
Cited 158 times since 2021 (34.7 per year) source: EuropePMC
Emerging infectious diseases, Volume 27, Issue 5, 1 1 2021, Pages 1405-1415 Monitoring SARS-CoV-2 Circulation and Diversity through Community Wastewater Sequencing, the Netherlands and Belgium. Izquierdo-Lara R, Elsinga G, Heijnen L, Munnink BBO, Schapendonk CME, Nieuwenhuijse D, Kon M, Lu L, Aarestrup FM, Lycett S, Medema G, Koopmans MPG, de Graaf M
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a major global health problem, and public health surveillance is crucial to monitor and prevent virus spread. Wastewater-based epidemiology has been proposed as an addition to disease-based surveillance because virus is shed in the feces of ≈40% of infected persons. We used next-generation sequencing of sewage samples to evaluate the diversity of SARS-CoV-2 at the community level in the Netherlands and Belgium. Phylo... Abstract
Cited 2 times since 2021 (0.4 per year) source: EuropePMC
BJS open, Volume 5, Issue 3, 1 1 2021, Pages zraa065 Effects of hospital preference for endovascular repair on postoperative mortality after elective abdominal aortic aneurysm repair: analysis of the Dutch Surgical Aneurysm Audit. Lijftogt N, Vahl AC, Karthaus EG, van der Willik EM, Amodio S, van Zwet EW, Hamming JF, Dutch Society of Vascular Surgery, the Steering Committee of the Dutch Surgical Aneurysm Audit, and the Dutch Institute for Clinical Auditing
Background: Increased use of endovascular aneurysm repair (EVAR) and reduced open surgical repair (OSR), has decreased postoperative mortality after elective repair of abdominal aortic aneurysms (AAAs). The choice between EVAR or OSR depends on aneurysm anatomy, and the experience and preference of the vascular surgeon, and therefore differs between hospitals. The aim of this study was to investigate the current mortality risk difference (RD) between EVAR and OSR, and the effect of hospital pref... Abstract
Cited 6 times since 2021 (1.3 per year) source: EuropePMC
Lupus science & medicine, Volume 8, Issue 1, 1 1 2021, Pages e000472 Effectiveness of a multidisciplinary clinical pathway for women with systemic lupus erythematosus and/or antiphospholipid syndrome. Wind M, Hendriks M, van Brussel BTJ, Eikenboom J, Allaart CF, Lamb HJ, Siebelink HJ, Ninaber MK, van Geloven N, van Lith JMM, Huizinga TWJ, Rabelink TJ, Sueters M, Teng YKO
Objectives: SLE and/or antiphospholipid syndrome (SLE/APS) are complex and rare systemic autoimmune diseases that predominantly affect women of childbearing age. Women with SLE/APS are at high risk of developing complications during pregnancy. Therefore, clinical practice guidelines recommend that patients with SLE/APS should receive multidisciplinary counselling before getting pregnant. We investigated the clinical effectiveness of implementing a multidisciplinary clinical pathway including pre... Abstract
Cited 64 times since 2021 (14.1 per year) source: EuropePMC
European heart journal, Volume 42, Issue 18, 1 1 2021, Pages 1742-1756 Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Koenig W, Fliser D, Laufs U, Speer T, eQTLGen consortium, BIOS consortium
Aims: Inflammation plays an important role in cardiovascular disease (CVD) development. The NOD-like receptor protein-3 (NLRP3) inflammasome contributes to the development of atherosclerosis in animal models. Components of the NLRP3 inflammasome pathway such as interleukin-1β can therapeutically be targeted. Associations of genetically determined inflammasome-mediated systemic inflammation with CVD and mortality in humans are unknown. Methods and results: We explored the association of genetic N... Abstract
Nature genetics, Volume 53, Issue 5, 1 1 2021, Pages 762 Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E,
Cited 16 times since 2021 (3.5 per year) source: EuropePMC
International journal of molecular sciences, Volume 22, Issue 9, 30 5 2021, Pages 4804 Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review. Sier VQ, van der Vorst JR, Quax PHA, de Vries MR, Zonoobi E, Vahrmeijer AL, Dekkers IA, de Geus-Oei LF, Smits AM, Cai W, Sier CFM, Goumans MJTH, Hawinkels LJAC
Molecular imaging of pathologic lesions can improve efficient detection of cancer and cardiovascular diseases. A shared pathophysiological feature is angiogenesis, the formation of new blood vessels. Endoglin (CD105) is a coreceptor for ligands of the Transforming Growth Factor-β (TGF-β) family and is highly expressed on angiogenic endothelial cells. Therefore, endoglin-based imaging has been explored to visualize lesions of the aforementioned diseases. This systematic review highlights the prog... Abstract
Cited 43 times since 2021 (9.4 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 8, 28 4 2021, Pages 647785 Post-ischemic Myocardial Inflammatory Response: A Complex and Dynamic Process Susceptible to Immunomodulatory Therapies. Pluijmert NJ, Atsma DE, Quax PHA
Following acute occlusion of a coronary artery causing myocardial ischemia and implementing first-line treatment involving rapid reperfusion, a dynamic and balanced inflammatory response is initiated to repair and remove damaged cells. Paradoxically, restoration of myocardial blood flow exacerbates cell damage as a result of myocardial ischemia-reperfusion (MI-R) injury, which eventually provokes accelerated apoptosis. In the end, the infarct size still corresponds to the subsequent risk of deve... Abstract
Cited 13 times since 2021 (2.9 per year) source: EuropePMC
JMIR mHealth and uHealth, Volume 9, Issue 4, 28 4 2021, Pages e26161 Impact of Mobile Health Devices for the Detection of Atrial Fibrillation: Systematic Review. Biersteker TE, Schalij MJ, Treskes RW
Background: Atrial fibrillation (AF) is the most common arrhythmia, and its prevalence is increasing. Early diagnosis is important to reduce the risk of stroke. Mobile health (mHealth) devices, such as single-lead electrocardiogram (ECG) devices, have been introduced to the worldwide consumer market over the past decade. Recent studies have assessed the usability of these devices for detection of AF, but it remains unclear if the use of mHealth devices leads to a higher AF detection rate. Object... Abstract
Cited 9 times since 2021 (2 per year) source: EuropePMC
International journal of colorectal disease, Volume 36, Issue 7, 27 4 2021, Pages 1507-1513 Normal inflammatory markers and acute appendicitis: a national multicentre prospective cohort analysis. de Jonge J, Scheijmans JCG, van Rossem CC, van Geloven AAW, Boermeester MA, Bemelman WA, Snapshot Appendicitis Collaborative Study group
Purpose: For the diagnosis of acute appendicitis, the combination of clinical and laboratory variables achieves high diagnostic accuracy. Nevertheless, appendicitis can present with normal laboratory tests of inflammation. The aim of this study was to investigate the incidence of normal inflammatory markers in patients operated for acute appendicitis. Methods: This is an analysis of data from a prospective, multicentre SNAPSHOT cohort study of patients with suspected acute appendicitis. Only pat... Abstract
Cited 18 times since 2021 (3.9 per year) source: EuropePMC
Diabetologia, Volume 64, Issue 7, 27 4 2021, Pages 1550-1562 Prognostic models for predicting the risk of foot ulcer or amputation in people with type 2 diabetes: a systematic review and external validation study. Beulens JWJ, Yauw JS, Elders PJM, Feenstra T, Herings R, Slieker RC, Moons KGM, Nijpels G, van der Heijden AA
Aims/hypothesis: Approximately 25% of people with type 2 diabetes experience a foot ulcer and their risk of amputation is 10-20 times higher than that of people without type 2 diabetes. Prognostic models can aid in targeted monitoring but an overview of their performance is lacking. This study aimed to systematically review prognostic models for the risk of foot ulcer or amputation and quantify their predictive performance in an independent cohort. Methods: A systematic review identified studies... Abstract
Cited 2 times since 2021 (0.4 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 8, Issue 5, 26 4 2021, Pages 47 The Role of Cell Tracing and Fate Mapping Experiments in Cardiac Outflow Tract Development, New Opportunities through Emerging Technologies. Peterson JC, Kelder TP, Goumans MJTH, Jongbloed MRM, DeRuiter MC
Whilst knowledge regarding the pathophysiology of congenital heart disease (CHDs) has advanced greatly in recent years, the underlying developmental processes affecting the cardiac outflow tract (OFT) such as bicuspid aortic valve, tetralogy of Fallot and transposition of the great arteries remain poorly understood. Common among CHDs affecting the OFT, is a large variation in disease phenotypes. Even though the different cell lineages contributing to OFT development have been studied for many de... Abstract