9197 results
Cited 26 times since 2019 (4.4 per year)
source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology,
Volume 33, Issue 9, 5 1 2019, Pages 10453-10468
Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43.
Schultz F, Swiatlowska P, Alvarez-Laviada A, Sanchez-Alonso JL, Song Q, de Vries AAF, Pijnappels DA, Ongstad E, Braga VMM, Entcheva E, Gourdie RG, Miragoli M, Gorelik J
Healthy cardiomyocytes are electrically coupled at the intercalated discs by gap junctions. In infarcted hearts, adverse gap-junctional remodeling occurs in the border zone, where cardiomyocytes are chemically and electrically influenced by myofibroblasts. The physical movement of these contacts remains unquantified. Using scanning ion conductance microscopy, we show that intercellular contacts between cardiomyocytes and myofibroblasts are highly dynamic, mainly owing to the edge dynamics (lamel...
Abstract
Cited 9 times since 2019 (1.5 per year)
source: EuropePMC
ChemistryOpen,
Volume 8, Issue 7, 4 1 2019, Pages 888-895
Creation of Conductive Graphene Materials by Bacterial Reduction Using <i>Shewanella Oneidensis</i>.
Lehner BAE, Janssen VAEC, Spiesz EM, Benz D, Brouns SJJ, Meyer AS, van der Zant HSJ
Graphene's maximized surface-to-volume ratio, high conductance, mechanical strength, and flexibility make it a promising nanomaterial. However, large-scale graphene production is typically cost-intensive. This manuscript describes a microbial reduction approach for producing graphene that utilizes the bacterium Shewanella oneidensis in combination with modern nanotechnology to enable a low-cost, large-scale production method. The bacterial reduction approach presented in this paper increase...
Abstract
Journal of affective disorders,
Volume 257, 4 1 2019, Pages 180-186
Supported self-help to prevent relapse or recurrence of depression: Who benefits most?
Dijkstra-Kersten SM, Biesheuvel-Leliefeld KE, van der Wouden JC, van Schaik DJ, Bosmans JE, van Marwijk HW, van der Horst HE
Background: This study aimed to identify subgroups for whom supported self-help preventive cognitive therapy (S-PCT) is more (cost)effective than treatment as usual (TAU) in preventing relapse and recurrence of major depression. Methods: We conducted a randomized controlled trial in which 248 remitted, recurrently depressed participants were randomized to S-PCT (n = 124) or TAU (n = 124). Clinical outcome was relapse or recurrence of major depressive disorder (SCID-I). We tested the moderating e...
Abstract
Cited 29 times since 2019 (4.9 per year)
source: EuropePMC
Neurology(R) neuroimmunology & neuroinflammation,
Volume 6, Issue 5, 3 1 2019, Pages e590
Long-term safety and efficacy of subcutaneous immunoglobulin IgPro20 in CIDP: PATH extension study.
van Schaik IN, Mielke O, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Durn BL, Cornblath DR, Merkies ISJ, PATH study group
Objective: To investigate the long-term safety and efficacy of weekly subcutaneous IgPro20 (Hizentra, CSL Behring) in chronic inflammatory demyelinating polyneuropathy (CIDP). Methods: In a 48-week open-label prospective extension study to the PATH study, patients were initially started on 0.2 g/kg or on 0.4 g/kg weekly and-if clinically stable-switched to 0.2 g/kg weekly after 24 weeks. Upon CIDP relapse on the 0.2 g/kg dose, 0.4 g/kg was (re)initiated. CIDP relapse was defined as a deteriorati...
Abstract
Cited 53 times since 2019 (9 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 32, Issue 9, 3 1 2019, Pages 1120-1127
Global Left Ventricular Myocardial Work Efficiency in Healthy Individuals and Patients with Cardiovascular Disease.
El Mahdiui M, van der Bijl P, Abou R, Ajmone Marsan N, Delgado V, Bax JJ
Background: Global left ventricular (LV) myocardial work efficiency, the ratio of constructive to wasted work in all LV segments, reflects the efficiency by which mechanical energy is expended during the cardiac cycle. Global LV myocardial work efficiency can be derived from LV pressure-strain loop analysis incorporating both noninvasively estimated blood pressure recordings and echocardiographic strain data. The aim of this study was to characterize global LV myocardial work efficiency in healt...
Abstract
The Annals of thoracic surgery,
Volume 109, Issue 1, 3 1 2019, Pages 308-309
Reply.
Petrus AHJ, Klautz RJM, Braun J
Abstract
Cited 5 times since 2019 (0.9 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 20, Issue 13, 2 1 2019, Pages E3251
Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve.
van de Pol V, Bons LR, Lodder K, Kurakula KB, Sanchez-Duffhues G, Siebelink HJ, Roos-Hesselink JW, DeRuiter MC, Goumans MJ
Bicuspid aortic valve (BAV), the most common congenital heart defect, is associated with an increased prevalence of aortic dilation, aortic rupture and aortic valve calcification. Endothelial cells (ECs) play a major role in vessel wall integrity. Little is known regarding EC function in BAV patients due to lack of patient derived primary ECs. Endothelial colony forming cells (ECFCs) have been reported to be a valid surrogate model for several cardiovascular pathologies, thereby facilitating an...
Abstract
Cited 8 times since 2019 (1.4 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 26, 1 1 2019, Pages 2170
Tornado-like flow in the Fontan circulation: insights from quantification and visualization of viscous energy loss rate using 4D flow MRI.
Rijnberg FM, van Assen HC, Hazekamp MG, Roest AAW
Abstract
Cited 37 times since 2019 (6.3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 21, Issue 7, 1 1 2019, Pages 993-994
EHRA White Paper: knowledge gaps in arrhythmia management-status 2019.
Goette A, Auricchio A, Boriani G, Braunschweig F, Terradellas JB, Burri H, Camm AJ, Crijns H, Dagres N, Deharo JC, Dobrev D, Hatala R, Hindricks G, Hohnloser SH, Leclercq C, Lewalter T, Lip GYH, Merino JL, Mont L, Prinzen F, Proclemer A, Pürerfellner H, Savelieva I, Schilling R, Steffel J, van Gelder IC, Zeppenfeld K, Zupan I, Heidbüchel H, ESC Scientific Document Group
Clinicians accept that there are many unknowns when we make diagnostic and therapeutic decisions. Acceptance of uncertainty is essential for the pursuit of the profession: bedside decisions must often be made on the basis of incomplete evidence. Over the years, physicians sometimes even do not realize anymore which the fundamental gaps in our knowledge are. As clinical scientists, however, we have to halt and consider what we do not know yet, and how we can move forward addressing those unknowns...
Abstract
Cited 10 times since 2019 (1.7 per year)
source: EuropePMC
Nature genetics,
Volume 51, Issue 7, 1 1 2019, Pages 1192-1193
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K,
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract
Cited 11 times since 2019 (1.9 per year)
source: EuropePMC
BMJ open,
Volume 9, Issue 7, 1 1 2019, Pages e029254
An observational study on survival rates of patients with out-of-hospital cardiac arrest in the Netherlands after improving the 'chain of survival'.
de Visser M, Bosch J, Bootsma M, Cannegieter S, van Dijk A, Heringhaus C, de Nooij J, Terpstra N, Peschanski N, Burggraaf K
Objectives: To evaluate the impact of implemented procedures for out-of-hospital cardiac arrests (OHCAs) by determining patient outcome defined as the percentage return of spontaneous circulation at arrival at the emergency department, and 3-month and 1-year-survival rates. Design: Observational study. Setting: Primary emergency medical care consisting of Advanced Life Support is given by ambulance nurses and secondary care by hospitals within the mid-western part of the Netherlands covering 750...
Abstract
The Journal of rheumatology,
Volume 46, Issue 9, 1 1 2019, Pages 1244-1245
Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening.
VAN Leeuwen NM, Boonstra M, Ajmone Marsan N, Ninaber MK, Huizinga TWJ, DE Vries-Bouwstra JK
Abstract
Cited 7 times since 2019 (1.2 per year)
source: EuropePMC
PloS one,
Volume 14, Issue 7, 1 1 2019, Pages e0218676
The modulation of facial mimicry by attachment tendencies and their underlying affiliation motives in 3-year-olds: An EMG study.
Vacaru SV, van Schaik JE, Hunnius S
From early in life, facial mimicry represents an important example of implicit non-verbal communication. Facial mimicry is conceived of as the automatic tendency to mimic another person's facial expressions and is thought to serve as a social glue among interaction partners. Although in adults mimicry has been shown to be moderated by the social context and one's needs to affiliate with others, evidence from behavioural mimicry studies suggest that 3-year-olds do not yet show sensitivi...
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
The Journal of infectious diseases,
Volume 220, Issue 4, 1 1 2019, Pages 624-634
Chemokine Receptor 7 Is Essential for Coxiella burnetii Whole-Cell Vaccine-Induced Cellular Immunity but Dispensable for Vaccine-Mediated Protective Immunity.
Chen C, van Schaik EJ, Gregory AE, Vigil A, Felgner PL, Hendrix LR, Faris R, Samuel JE
Background: Protective immunity against Coxiella burnetii infection is conferred by vaccination with virulent (PI-WCV), but not avirulent (PII-WCV) whole-cell inactivated bacterium. The only well-characterized antigenic difference between virulent and avirulent C. burnetii is they have smooth and rough lipopolysaccharide (LPS), respectively. Methods: Mice were vaccinated with PI-WCV and PII-WCV. Humoral and cellular responses were evaluated using protein chip microarrays and ELISpots, respective...
Abstract
Cited 29 times since 2019 (4.9 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 27, 1 1 2019, Pages 2206-2214
Impact of recurrent mitral regurgitation after mitral valve repair for functional mitral regurgitation: long-term analysis of competing outcomes.
Petrus AHJ, Dekkers OM, Tops LF, Timmer E, Klautz RJM, Braun J
Aims: Recurrent mitral regurgitation (MR) has been reported after mitral valve repair for functional MR. However, the impact of recurrent MR on long-term survival remains poorly defined. In the present study, mortality-adjusted recurrent MR rates, the clinical impact of recurrent MR and its determinants were studied in patients after mitral valve repair with revascularization for functional MR in the setting of ischaemic heart disease. Methods and results: Long-term clinical and echocardiographi...
Abstract
Cited 47 times since 2019 (8 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 26, 1 1 2019, Pages 2142-2151
Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry.
Gili S, Cammann VL, Schlossbauer SA, Kato K, D'Ascenzo F, Di Vece D, Jurisic S, Micek J, Obeid S, Bacchi B, Szawan KA, Famos F, Sarcon A, Levinson R, Ding KJ, Seifert B, Lenoir O, Bossone E, Citro R, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz JD, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Gaita F, Di Mario C, Wischnewsky MB, Bax JJ, Prasad A, Böhm M, Ruschitzka F, Lüscher TF, Ghadri JR, Templin C
Aims: We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). Methods and results: We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were...
Abstract
Cited 101 times since 2019 (17.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 74, Issue 4, 1 1 2019, Pages 550-563
Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.
Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula J, Lancellotti P, Bax JJ, Généreux P, Pibarot P
Background: The optimal timing of intervention in patients with asymptomatic severe aortic stenosis (AS) remains controversial. Objectives: This multicenter study sought to test and validate the prognostic value of the staging of cardiac damage in patients with asymptomatic moderate to severe AS. Methods: This study retrospectively analyzed the clinical, Doppler echocardiographic, and outcome data that were prospectively collected in 735 asymptomatic patients (71 ± 14 years of age; 60% men) with...
Abstract
Cited 20 times since 2019 (3.4 per year)
source: EuropePMC
Academic medicine : journal of the Association of American Medical Colleges,
Volume 94, Issue 7, 1 1 2019, Pages 975-982
Exemplary Learning Environments for the Health Professions: A Vision.
van Schaik SM, Reeves SA, Headrick LA
In this article, the authors propose a vision for exemplary learning environments in which everyone involved in health professions education and health care collaborates toward optimal health for individuals, populations, and communities. Learning environments in the health professions can be conceptualized as complex adaptive systems, defined as a collection of individual agents whose actions are interconnected and follow a set of shared "simple rules." Using principles from complex a...
Abstract
Cited 7 times since 2019 (1.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 124, Issue 6, 1 1 2019, Pages 892-898
Defining Subclinical Myocardial Dysfunction and Implications for Patients With Diabetes Mellitus and Preserved Ejection Fraction.
Ng ACT, Bertini M, Ewe SH, van der Velde ET, Leung DY, Delgado V, Bax JJ
Left ventricular (LV) global longitudinal strain (GLS) can detect subclinical myocardial systolic dysfunction in individuals with diabetes. The present study investigates the clinical usefulness and incremental net benefit of identifying subclinical myocardial systolic dysfunction in individuals with diabetes. A cohort of 397 type 2 diabetic individuals was followed up for the occurrence of all-cause mortality. Clinical and echocardiographic data of diabetic patients were assessed retrospectivel...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 56, Issue 1, 1 1 2019, Pages 210-212
Management of incidentally diagnosed pulmonary artery dissection in patients with pulmonary arterial hypertension.
Nuche J, Montero Cabezas JM, Alonso Charterina S, Escribano Subías P
Pulmonary artery dissection is a rare entity, usually discovered post-mortem. In recent years, reported cases of living patients with a pulmonary artery dissection are growing and represent a challenging situation for clinicians.
Abstract
