6125 results
Cited 28 times since 2004 (1.3 per year)
source: EuropePMC
Blood,
Volume 103, Issue 10, 22 4 2004, Pages 3777-3782
Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol.
Espirito Santo SM, Pires NM, Boesten LS, Gerritsen G, Bovenschen N, van Dijk KW, Jukema JW, Princen HM, Bensadoun A, Li WP, Herz J, Havekes LM, van Vlijmen BJ
The low-density lipoprotein (LDL) receptor-related protein (LRP) has a well-established role in the hepatic removal of atherogenic apolipoprotein E (APOE)-rich remnant lipoproteins from plasma. In addition, LRP recognizes multiple distinct pro- and antiatherogenic ligands in vitro. Here, we investigated the role of hepatic LRP in atherogenesis independent of its role in removal of APOE-rich remnant lipoproteins. Mice that allow inducible inactivation of hepatic LRP were combined with LDL recepto...
Abstract
Cited 20 times since 2004 (0.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 90, Issue 1, 1 1 2004, Pages 97-98
Atrial and brain natriuretic peptides as markers of response to resynchronisation therapy.
Molhoek SG, Bax JJ, van Erven L, Bootsma M, Steendijk P, Lentjes E, Boersma E, van der Laarse A, van der Wall EE, Schalij MJ
Abstract
Cited 64 times since 2004 (3 per year)
source: EuropePMC
European journal of clinical investigation,
Volume 34, Issue 1, 1 1 2004, Pages 21-28
Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS).
Klerkx AH, de Grooth GJ, Zwinderman AH, Jukema JW, Kuivenhoven JA, Kastelein JJ
Background: The TaqIB polymorphism in the cholesteryl ester transfer protein (CETP) gene is associated with HDL-C, progression of coronary artery disease (CAD) and response to pravastatin treatment in men with angiographically proven CAD (REGRESS). We hypothesized that differences in CETP concentration could explain these associations and now investigated whether CETP concentration is an independent determinant of these parameters. Materials and methods: Plasma CETP concentrations at baseline an...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 12, Issue 1, 1 1 2004, Pages 13-17
Genetic programme of cardiogenesis: implications for therapeutic application.
van Tuyn J, de Vries AA, van der Laarse A, Schalij MJ, van der Wall EE, Atsma DE
It has become accepted that new cardiomyocytes can be derived from stem cells. Although the potential for therapeutic application is evident, the reported efficiency of differentiation varies greatly from 0.02 to 54%. To obtain clinically relevant numbers of newly differentiated cardiac cells, stem cell differentiation should be as efficient as possible. A plausible way to increase the efficiency of differentiation of stem cells into cardiomyocytes is through the introduction of cardiac specific...
Abstract
Cited 12 times since 2004 (0.6 per year)
source: EuropePMC
American heart journal,
Volume 147, Issue 1, 1 1 2004, Pages 181-186
Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events.
Boekholdt SM, Peters RJ, de Maat MP, Zwinderman AH, van Der Wall EE, Reitsma PH, Jukema JW, Kastelein JJ
Background: The PlA1A2 polymorphism of glycoprotein IIIa (GPIIIa), which affects postoccupancy signaling by the platelet fibrinogen receptor IIbIIIa, has been investigated as a potential genetic risk factor for cardiovascular events in numerous studies, without consistent results. We investigated whether the effect of this genetic variant of the platelet fibrinogen receptor on the risk of cardiovascular events is affected by fibrinogen plasma levels. Methods: The GPIIIa PlA1A2 polymorphism and f...
Abstract
Cited 56 times since 2004 (2.6 per year)
source: EuropePMC
Archives of internal medicine,
Volume 164, Issue 1, 1 1 2004, Pages 40-44
Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses.
Hennekens CH, Sacks FM, Tonkin A, Jukema JW, Byington RP, Pitt B, Berry DA, Berry SM, Ford NF, Walker AJ, Natarajan K, Sheng-Lin C, Fiedorek FT, Belder R
Background: In randomized trials of secondary prevention, pravastatin sodium and aspirin reduce risks of cardiovascular disease. Pravastatin has a predominantly delayed antiatherogenic effect, and aspirin has an immediate antiplatelet effect, raising the possibility of additive clinical benefits. Methods: In 5 randomized trials of secondary prevention with pravastatin (40 mg/d), comprising 73 900 patient-years of observation, aspirin use was also prescribed in varying frequencies, and data were...
Abstract
Cited 21 times since 2004 (1 per year)
source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology,
Volume 5, Issue 1, 1 1 2004, Pages 34-40
Radiofrequency catheter ablation of ventricular tachycardia guided by intracardiac echocardiography.
Jongbloed MR, Bax JJ, van der Burg AE, Van der Wall EE, Schalij MJ
Aims: Ventricular tachycardia (VT) frequently has an anatomical substrate. Identification of areas prone to arrhythmogenicity facilitates radiofrequency catheter ablation (RFCA). Furthermore, direct monitoring of complications potentially increases safety of RFCA. The aim of this study was to evaluate the feasibility of guiding RFCA of VT with intracardiac echocardiography (ICE), in order to improve outcome and procedural safety. Methods and results: Eleven patients (age 59 +/- 15 years) with dr...
Abstract
Cited 9 times since 2004 (0.4 per year)
source: EuropePMC
Pediatric hematology and oncology,
Volume 21, Issue 1, 1 1 2004, Pages 1-8
A single institutional experience: is epoetin alpha effective in anemic children with cancer?
Yilmaz D, Cetingül N, Kantar M, Oniz H, Kansoy S, Kavakli K
The authors aimed to investigate the efficacy of epoetin-alpha on hemoglobin levels and red cell transfusion requirement in children with both hematologic malignancy (HM, n = 27) and solid tumors (ST, n = 14). Epoetin-alpha was given (150 U/kg or 250 U/kg, thrice weekly) for 12 weeks. Epoetin alpha significantly increased the hemoglobin levels at the 2nd and 3rd months of therapy (p
Abstract
Cited 8 times since 2004 (0.4 per year)
source: EuropePMC
International journal of psychiatry in clinical practice,
Volume 8, Issue 4, 1 1 2004, Pages 205-211
A prospective randomized single-blind, multicenter trial comparing the efficacy and safety of paroxetine with and without quetiapine therapy in depression associated with anxiety.
Yargic LI, Corapcioglu A, Kocabasoglu N, Erdogan A, Koroglu G, Yilmaz D
OBJECTIVE To evaluate quetiapine as an adjunct to paroxetine in patients with comorbid depression and anxiety. METHOD Prospective, multicenter, single-blind trial of patients with DSM-IV major depression and associated anxiety, who were randomized to an 8-week treatment with paroxetine alone (n=54) or paroxetine+quetiapine (n=58). Quetiapine was dosed to 200 mg/day and paroxetine to 60 mg/day, as required. RESULTS Decrease in HAM-A scores was significantly greater in the combined therapy group t...
Abstract
Cited 119 times since 2004 (5.6 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 2, 1 1 2004, Pages 96-103
Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery.
Kertai MD, Boersma E, Westerhout CM, van Domburg R, Klein J, Bax JJ, van Urk H, Poldermans D
Purpose: To assess the potential long-term beneficial effects of statin use after successful abdominal aortic surgery. Methods: Between 1991 and 2001, 570 patients underwent abdominal aortic aneurysm repair at the Erasmus Medical Center. Of the 519 patients (91%) who survived surgery beyond 30 days, 510 (98%) were followed for a median of 4.7 years (interquartile range, 2.7 to 7.3 years). These patients were evaluated for use of statins and beta-blockers, and for clinical risk factors (e.g., adv...
Abstract
Cited 91 times since 2004 (4.3 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 1, 1 1 2004, Pages 8-13
Aortic stenosis: an underestimated risk factor for perioperative complications in patients undergoing noncardiac surgery.
Kertai MD, Bountioukos M, Boersma E, Bax JJ, Thomson IR, Sozzi F, Klein J, Roelandt JR, Poldermans D
Purpose: To determine the incidence of perioperative events in patients with aortic stenosis undergoing noncardiac surgery. Methods: We studied 108 patients with moderate (mean gradient, 25 to 49 mm Hg) or severe (mean gradient, > or =50 mm Hg) aortic stenosis and 216 controls who underwent noncardiac surgery between 1991 and 2000 at Erasmus Medical Center. Controls were selected based on calendar year and type of surgery. Details of clinical risk factors, type of surgery, and perioperative m...
Abstract
Cited 24 times since 2004 (1.1 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 6, Issue 4, 1 1 2004, Pages 767-776
Accurate and reproducible mitral valvular blood flow measurement with three-directional velocity-encoded magnetic resonance imaging.
Westenberg JJ, Danilouchkine MG, Doornbos J, Bax JJ, van der Geest RJ, Labadie G, Lamb HJ, Versteegh MI, de Roos A, Reiber JH
A new method for quantifying the transvalvular flow through the mitral valve (MV) based on three-directional velocity-encoded magnetic resonance imaging (MRI) is presented. For thirty time phases during one cardiac cycle, the three-dimensional (3D) velocity vector field of the blood flow is reconstructed from the MRI measurement. Retrospectively, for each time phase, the MV-plane is indicated manually in the velocity data and the flow through this plane is determined, representing the MV flow. M...
Abstract
Cited 11 times since 2004 (0.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 93, Issue 1, 1 1 2004, Pages 14-17
Incidence of recovery of contractile function following revascularization in patients with ischemic left ventricular dysfunction.
Schinkel AF, Poldermans D, Vanoverschelde JL, Elhendy A, Boersma E, Roelandt JR, Bax JJ
Contractile function in patients with ischemic left ventricular (LV) dysfunction may improve after myocardial revascularization. Currently, the incidence of contractile function recovery after revascularization in these patients is unclear. The aim of this study was to assess the incidence of function improvement after myocardial revascularization in patients with ischemic LV dysfunction. A total of 258 consecutive patients (aged 59 +/- 12 years) with severely depressed LV ejection fractions (EF...
Abstract
Cited 67 times since 2004 (3.2 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 89, Issue 1, 1 1 2004, Pages 71-75
Increased prevalence of regurgitant valvular heart disease in acromegaly.
Pereira AM, van Thiel SW, Lindner JR, Roelfsema F, van der Wall EE, Morreau H, Smit JW, Romijn JA, Bax JJ
Cardiac involvement is common in acromegaly, but the prevalence of valvular abnormalities in patients with acromegaly has not been documented and is the topic of this study. In a prospective study design, 40 consecutive patients with acromegaly and 120 control subjects (matched for age, sex, hypertension, and left ventricular systolic function) were studied. All patients and controls were evaluated using conventional two-dimensional and Doppler echocardiography. Significant valve disease was mor...
Abstract
Cited 20 times since 2004 (0.9 per year)
source: EuropePMC
Anesthesiology,
Volume 100, Issue 1, 1 1 2004, Pages 4-7
Is there any reason to withhold beta blockers from high-risk patients with coronary artery disease during surgery?
Kertai MD, Bax JJ, Klein J, Poldermans D
Abstract
Cited 138 times since 2003 (6.5 per year)
source: EuropePMC
Circulation,
Volume 109, Issue 3, 29 5 2004, Pages 393-398
Toll-like receptor 4 is involved in outward arterial remodeling.
Hollestelle SC, De Vries MR, Van Keulen JK, Schoneveld AH, Vink A, Strijder CF, Van Middelaar BJ, Pasterkamp G, Quax PH, De Kleijn DP
Background: Toll-like receptor 4 (Tlr4) is the receptor for exogenous lipopolysaccharides (LPS). Expression of endogenous Tlr4 ligands, heat shock protein 60 (Hsp60) and extra domain A of fibronectin, has been observed in arthritic and oncological specimens in which matrix turnover is an important feature. In atherosclerosis, outward remodeling is characterized by matrix turnover and a structural change in arterial circumference and is associated with a vulnerable plaque phenotype. Since Tlr4 li...
Abstract
Cited 2 times since 2003 (0.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 529-531
Viability assessment: nuclear imaging vs. dobutamine echocardiography.
Bax JJ, van der Wall EE
Abstract
Cited 38 times since 2003 (1.8 per year)
source: EuropePMC
European journal of heart failure,
Volume 5, Issue 6, 1 1 2003, Pages 767-774
Screening for left ventricular dysfunction using a hand-carried cardiac ultrasound device.
Vourvouri EC, Schinkel AF, Roelandt JR, Boomsma F, Sianos G, Bountioukos M, Sozzi FB, Rizzello V, Bax JJ, Karvounis HI, Poldermans D
Background: The hand-carried cardiac ultrasound (HCU) device is a recently introduced imaging device, which may be potentially useful in the primary care setting. Aim: To test the screening potential of a HCU for the detection of left ventricular (LV) dysfunction by evaluating LV ejection fraction (LVEF) and inferior vena cava (IVC) collapse. Standard echocardiographic system (SE) and plasma brain natriuretic peptide (BNP) measurements were used as a reference. Methods: Eighty-eight consecutive...
Abstract
Cited 11 times since 2003 (0.5 per year)
source: EuropePMC
Nuklearmedizin. Nuclear medicine,
Volume 42, Issue 6, 1 1 2003, Pages 240-243
Iodine excretion during stimulation with rhTSH in differentiated thyroid carcinoma.
Löffler M, Weckesser M, Franzius C, Kies P, Schober O
Aim: Elevated iodine intake is a serious problem in the diagnostic and therapeutic application of (131)iodine in patients with differentiated thyroid cancer. Therefore, iodine avoidance is necessary 3 months in advance. Additionally, endogenous stimulation requires withdrawal of thyroid hormone substitution for 4 weeks. Exogenous stimulation using recombinant human TSH (rhTSH) enables the continuous substitution of levothyroxine, which contains 65.4% of its molecular weight in iodine. Thus, a su...
Abstract
Cited 5 times since 2003 (0.2 per year)
source: EuropePMC
Lancet (London, England),
Volume 362, Issue 9401, 1 1 2003, Pages 2118-9; author reply 2119-20
Selective decontamination of digestive tract in intensive care.
Bonten MJ, Kluytmans J, de Smet AM, Bootsma M, Hoes A
Abstract
