Research

Publications

Below you can find a list of our published research.

9543 results

Cited 221 times since 2009 (13.7 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 54, Issue 16, 1 1 2009, Pages 1524-1532 Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging. Rijzewijk LJ, van der Meer RW, Lamb HJ, de Jong HW, Lubberink M, Romijn JA, Bax JJ, de Roos A, Twisk JW, Heine RJ, Lammertsma AA, Smit JW, Diamant M

Objectives: This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated type 2 diabetes with verified absence of cardiac ischemia, and age-matched control subjects, and to assess the association with myocardial function. Background: Metabolic abnormalities, particularly an excessive exposure of the heart to circulating nonesterified fatty acids and myocardial insulin resistance are considered importan... Abstract

The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 1, 26 4 2009, Pages 240-241 Balloon sizing in surgical ventricular restoration: what volume are we targeting? ten Brinke EA, Klautz RJ, Steendijk P

Abstract

Cited 62 times since 2009 (3.8 per year) source: EuropePMC

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, Volume 12, Issue 9, 26 4 2009, Pages 862-867 Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Toorenvliet BR, Swank H, Schoones JW, Hamming JF, Bemelman WA

Aim: This systematic review aimed to evaluate the efficacy, morbidity and mortality of laparoscopic peritoneal lavage for patients with perforated diverticulitis. Method: We searched PubMed, EMBASE, Web of Science, the Cochrane Library and CINAHL databases, Google Scholar and five major publisher websites without language restriction. All articles which reported the use of laparoscopic peritoneal lavage for patients with perforated diverticulitis were included. Results: Two prospective cohort st... Abstract

Cited 221 times since 2009 (13.7 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 10, 26 4 2009, Pages 1398-1401 Findings from left ventricular strain and strain rate imaging in asymptomatic patients with type 2 diabetes mellitus. Ng AC, Delgado V, Bertini M, van der Meer RW, Rijzewijk LJ, Shanks M, Nucifora G, Smit JW, Diamant M, Romijn JA, de Roos A, Leung DY, Lamb HJ, Bax JJ

Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy have not been well documented. LV multidirectional strain and strain rate analyses by 2-dimensional speckle tracking were used to detect subtle myocardial dysfunction in 47 asymptomatic, male patients (age 57 +/- 6 years) with type 2 diabetes mellitus. The results were compared to those from 53 male controls matched by age, body mass index, and body surface area. No differences were found in the LV end-... Abstract

Cited 80 times since 2009 (4.9 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 297, Issue 5, 25 4 2009, Pages H1606-16 Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension. Umar S, de Visser YP, Steendijk P, Schutte CI, Laghmani el H, Wagenaar GT, Bax WH, Mantikou E, Pijnappels DA, Atsma DE, Schalij MJ, van der Wall EE, van der Laarse A

Pulmonary arterial hypertension (PAH) is a chronic lung disease that leads to right ventricular (RV) hypertrophy (RVH), remodeling, and failure. We tested treatment with bone marrow-derived mesenchymal stem cells (MSCs) obtained from donor rats with monocrotaline (MCT)-induced PAH to recipient rats with MCT-induced PAH on pulmonary artery pressure, lung pathology, and RV function. This model was chosen to mimic autologous MSC therapy. On day 1, PAH was induced by MCT (60 mg/kg) in 20 female Wist... Abstract

Cited 24 times since 2009 (1.5 per year) source: EuropePMC

Nature reviews. Gastroenterology & hepatology, Volume 6, Issue 11, 22 4 2009, Pages 671-678 Endoscopic and pathological aspects of colitis-associated dysplasia. van Schaik FD, Offerhaus GJ, Schipper ME, Siersema PD, Vleggaar FP, Oldenburg B

The risk of developing colorectal cancer in patients with colitis-associated dysplasia is considerable. Surveillance programs in patients with ulcerative colitis and Crohn's disease aim to detect dysplastic lesions early and rely heavily on taking random biopsy samples along the length of the colon. Diagnosing dysplasia can be difficult because of the heterogeneous endoscopic appearance of dysplasia and the poor interobserver agreement among pathologists when grading dysplasia. Colitis-asso... Abstract

Cited 18 times since 2009 (1.1 per year) source: EuropePMC

Preventive veterinary medicine, Volume 92, Issue 3, 16 3 2009, Pages 256-266 Evaluation of Ziehl-Neelsen stained faecal smear and ELISA as tools for surveillance of clinical paratuberculosis in cattle in the Netherlands. Weber MF, Verhoeff J, van Schaik G, van Maanen C

Testing cattle suspected of clinical paratuberculosis is an important element of surveillance of paratuberculosis. The aim of this study was to evaluate the diagnostic-test characteristics of microscopic examination of Ziehl-Neelsen stained faecal smears for acid-fast Mycobacteria (ZN-test) and serum-ELISA in cattle suspected of clinical paratuberculosis in the Netherlands. Results of all samples submitted for ZN-test and serum-ELISA between April 2003 and April 2006 to our laboratory were retri... Abstract

Cited 86 times since 2009 (5.3 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 1, 16 3 2009, Pages 57-64 Intra-observer and interobserver variability of biventricular function, volumes and mass in patients with congenital heart disease measured by CMR imaging. Luijnenburg SE, Robbers-Visser D, Moelker A, Vliegen HW, Mulder BJ, Helbing WA

Cardiovascular magnetic resonance (CMR) imaging provides highly accurate measurements of biventricular volumes and mass and is frequently used in the follow-up of patients with acquired and congenital heart disease (CHD). Data on reproducibility are limited in patients with CHD, while measurements should be reproducible, since CMR imaging has a main contribution to decision making and timing of (re)interventions. The aim of this study was to assess intra-observer and interobserver variability of... Abstract

Cited 7 times since 2009 (0.4 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 1, 16 3 2009, Pages 19-25 Limited value of digital subtraction angiography in the evaluation of cell-based therapy in patients with limb ischemia. van Tongeren RB, Hamming JF, le Cessie S, van Erkel AR, van Bockel JH

Cell-based therapy has been proposed as a novel strategy for patients with severe peripheral arterial disease by stimulating vascular growth. In clinical studies of this therapy, the emphasis has been on demonstrating recovery of clinical parameters, rather than on evaluation of blood flow recovery. Angiography is still the gold standard for the assessment of lower leg arteries. Therefore, we studied the usefulness of angiography in the evaluation of cell-based therapy. Sixteen patients with cri... Abstract

Cited 13 times since 2009 (0.8 per year) source: EuropePMC

Lung cancer (Amsterdam, Netherlands), Volume 69, Issue 1, 15 3 2009, Pages 60-65 EUS-FNA in the preoperative staging of non-small cell lung cancer. Talebian M, von Bartheld MB, Braun J, Versteegh MI, Dekkers OM, Rabe KF, Annema JT

Background: According to current guidelines, transesophageal ultrasound-guided fine needle aspiration (EUS-FNA) can be performed as an alternative for surgical staging to confirm mediastinal metastases in patients with non-small cell lung cancer (NSCLC). To date however, data regarding the routine use of EUS-FNA in the preoperative staging of unselected patients with NSCLC are limited. Aims and objectives: (1) To evaluate the diagnostic value of EUS-FNA in consecutive, patients with NSCLC regard... Abstract

Cited 40 times since 2009 (2.5 per year) source: EuropePMC

Journal of lipid research, Volume 51, Issue 5, 14 2 2009, Pages 1201-1207 Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. Polisecki E, Peter I, Simon JS, Hegele RA, Robertson M, Ford I, Shepherd J, Packard C, Jukema JW, de Craen AJ, Westendorp RG, Buckley BM, Schaefer EJ, Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators

Niemann-Pick C1-like 1 protein (NPC1L1) plays a critical role in intestinal cholesterol absorption. Our objective was to examine whether five variants (-133A>G, -18A>C, L272L, V1296V, and U3_28650A>G) at the NPC1L1 gene have effects on lipid levels, prevalence, and incidence of coronary heart disease (CHD) and lipid-lowering response to pravastatin. We studied 5,804 elderly participants from the PROSPER study, who were randomized to prava-statin 40 mg/day or placebo and were followed on... Abstract

Cited 322 times since 2009 (19.9 per year) source: EuropePMC

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 27, Issue 31, 14 2 2009, Pages 5195-5201 Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study. Cilloni D, Renneville A, Hermitte F, Hills RK, Daly S, Jovanovic JV, Gottardi E, Fava M, Schnittger S, Weiss T, Izzo B, Nomdedeu J, van der Heijden A, van der Reijden BA, Jansen JH, van der Velden VH, Ommen H, Preudhomme C, Saglio G, Grimwade D

Purpose: Risk stratification in acute myeloid leukemia (AML) is currently based on pretreatment characteristics. It remains to be established whether relapse risk can be better predicted through assessment of minimal residual disease (MRD). One proposed marker is the Wilms tumor gene WT1, which is overexpressed in most patients with AML, thus providing a putative target for immunotherapy, although in the absence of a standardized assay, its utility for MRD monitoring remains controversial. Patie... Abstract

Cited 11 times since 2009 (0.7 per year) source: EuropePMC

Pacing and clinical electrophysiology : PACE, Volume 32, Issue 11, 10 2 2009, Pages e18-20 Different mechanisms underlying consecutive, postoperative atrial tachyarrhythmias in a Fontan patient. De Groot NM, Blom N, Vd Wall EE, Schalij MJ

Introduction: Atrial tachyarrhythmias (AT) frequently develop later after a Fontan operation and can be successfully treated by ablative therapy. However, new arrhythmias often develop. Methods and results: Consecutive AT emerging in a Fontan patient were ablated using three-dimensional electro-anatomical mapping. During a 6-year period, nine different AT were ablated, including intraatrial reentrant AT (N=5), focal AT (N=3), and focal atrial fibrillation (N=1) originating from distinct right at... Abstract

Cited 30 times since 2009 (1.8 per year) source: EuropePMC

Acta physiologica (Oxford, England), Volume 198, Issue 1, 6 1 2009, Pages 37-46 Single-beat estimation of the left ventricular end-systolic pressure-volume relationship in patients with heart failure. ten Brinke EA, Klautz RJ, Verwey HF, van der Wall EE, Dion RA, Steendijk P

Aim: The end-systolic pressure-volume relationship (ESPVR) constructed from multiple pressure-volume (PV) loops acquired during load intervention is an established method to asses left ventricular (LV) contractility. We tested the accuracy of simplified single-beat (SB) ESPVR estimation in patients with severe heart failure. Methods: Nineteen heart failure patients (NYHA III-IV) scheduled for surgical ventricular restoration and/or restrictive mitral annuloplasty and 12 patients with normal LV f... Abstract

Cited 234 times since 2009 (14.4 per year) source: EuropePMC

Journal of human evolution, Volume 57, Issue 4, 3 1 2009, Pages 392-400 The Expensive Brain: a framework for explaining evolutionary changes in brain size. Isler K, van Schaik CP

To explain variation in relative brain size among homoiothermic vertebrates, we propose the Expensive Brain hypothesis as a unifying explanatory framework. It claims that the costs of a relatively large brain must be met by any combination of increased total energy turnover or reduced energy allocation to another expensive function such as digestion, locomotion, or production (growth and reproduction). Focusing on the energetic costs of brain enlargement, a comparative analysis of the largest ma... Abstract

Cited 3 times since 2009 (0.2 per year) source: EuropePMC

Optics express, Volume 17, Issue 19, 1 1 2009, Pages 16969-16979 Detection and characterization of carbon contamination on EUV multilayer mirrors. Chen J, Louis E, Lee CJ, Wormeester H, Kunze R, Schmidt H, Schneider D, Moors R, van Schaik W, Lubomska M, Bijkerk F

In this paper, we detect and characterize the carbon contamination layers that are formed during the illumination of extreme ultraviolet (EUV) multilayer mirrors. The EUV induced carbon layers were characterized ex situ using spectroscopic ellipsometry (SE) and laser generated surface acoustic waves (LG-SAW). We show that both LG-SAW and SE are very sensitive for measuring carbon layers, even in the presence of the highly heterogeneous structure of the multilayer. SE has better overall sensitivi... Abstract

Cited 14 times since 2009 (0.9 per year) source: EuropePMC

Journal of rehabilitation medicine, Volume 41, Issue 9, 1 1 2009, Pages 746-750 Limited upper limb functioning has impact on restrictions in participation and autonomy of patients with hereditary motor and sensory neuropathy 1a. Videler AJ, Beelen A, van Schaik IN, de Visser M, Nollet F

Objective: To evaluate upper limb functioning, restrictions on participation and the independent contribution of upper and lower limb disability to participation in hereditary motor and sensory neuropathy 1a. Design: Descriptive cross-sectional study. Subjects: Forty-nine patients with hereditary motor and sensory neuropathy 1a. Methods: Perceived upper limb functioning was evaluated using the Michigan Hand Outcomes Questionnaire and participation restrictions with the Impact on Participation an... Abstract

Cited 58 times since 2009 (3.6 per year) source: EuropePMC

Pharmacoepidemiology and drug safety, Volume 18, Issue 9, 1 1 2009, Pages 770-777 Miglustat (Zavesca) in type 1 Gaucher disease: 5-year results of a post-authorisation safety surveillance programme. Hollak CE, Hughes D, van Schaik IN, Schwierin B, Bembi B

Purpose: Miglustat (Zavesca) is an orally-available substrate reduction therapy (SRT) for treatment of mild-to-moderate type 1 Gaucher disease (GD1) in adult patients unsuitable for enzyme replacement therapy (ERT). Miglustat has not been evaluated in children with GD1, and is not used during pregnancy and breast-feeding. A non-interventional, prospective, web-based safety surveillance programme was initiated at the time of the European launch of miglustat in 2003, and is ongoing. We report the... Abstract

Cited 36 times since 2009 (2.2 per year) source: EuropePMC

The Journal of bone and joint surgery. British volume, Volume 91, Issue 9, 1 1 2009, Pages 1134-1141 Ceramic-on-metal bearings in total hip replacement: whole blood metal ion levels and analysis of retrieved components. Isaac GH, Brockett C, Breckon A, van der Jagt D, Williams S, Hardaker C, Fisher J, Schepers A

This study reports on ceramic-on-metal (CoM) bearings in total hip replacement. Whole blood metal ion levels were measured. The median increase in chromium and cobalt at 12 months was 0.08 microg/1 and 0.22 microg/1, respectively, in CoM bearings. Comparable values for metal-on-metal (MoM) were 0.48 microg/1 and 0.32 microg/1. The chromium levels were significantly lower in CoM than in MoM bearings (p = 0.02). The cobalt levels were lower, but the difference was not significant. Examination of t... Abstract

Cited 52 times since 2009 (3.2 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 54, Issue 14, 1 1 2009, Pages 1317-1325 Effects of cardiac resynchronization therapy on left ventricular twist. Bertini M, Marsan NA, Delgado V, van Bommel RJ, Nucifora G, Borleffs CJ, Boriani G, Biffi M, Holman ER, van der Wall EE, Schalij MJ, Bax JJ

Objectives: This study explored the effects of cardiac resynchronization therapy (CRT) on left ventricular (LV) twist, particularly in relation to LV lead position. Background: LV twist is emerging as a comprehensive index of LV function. Methods: Eighty heart failure patients were included. Two-dimensional echocardiography was performed at baseline, immediately after CRT, and at 6-month follow-up. Speckle-tracking analysis was applied to assess LV twist. The LV lead was placed preferably in a (... Abstract