Research

Publications

Below you can find a list of our published research.

9543 results

Cited 49 times since 2007 (2.7 per year) source: EuropePMC

Veterinary journal (London, England : 1997), Volume 177, Issue 2, 6 1 2007, Pages 222-230 Clinical course of digital dermatitis lesions in an endemically infected herd without preventive herd strategies. Holzhauer M, Bartels CJ, Döpfer D, van Schaik G

Lactating Holstein-Friesian dairy cows in four separately housed groups in a herd with endemic digital dermatitis (DD) were monitored weekly for 4 weeks in December 2004 for the presence of and transition between five stages (M0-M4) of DD. Cows were also monitored for the presence of heel horn erosion (HHE) and interdigital hyperplasia. Prior to the study, two groups had been housed indoors on a high or low energy ration, one group had been grazed and one was a dry cow group. All cows received t... Abstract

Cited 132 times since 2007 (7.2 per year) source: EuropePMC

The American journal of cardiology, Volume 100, Issue 6, 5 1 2007, Pages 930-936 Comparison of myocardial infarct size assessed with contrast-enhanced magnetic resonance imaging and left ventricular function and volumes to predict mortality in patients with healed myocardial infarction. Roes SD, Kelle S, Kaandorp TA, Kokocinski T, Poldermans D, Lamb HJ, Boersma E, van der Wall EE, Fleck E, de Roos A, Nagel E, Bax JJ

Currently, left ventricular (LV) ejection fraction (EF) and/or LV volumes are the established predictors of mortality in patients with coronary artery disease (CAD) and severe LV dysfunction. With contrast-enhanced magnetic resonance imaging (MRI), precise delineation of infarct size is now possible. The relative merits of LVEF/LV volumes and infarct size to predict long-term outcome are unknown. The purpose of this study was to determine the predictive value of infarct size assessed with contra... Abstract

Cited 25 times since 2007 (1.4 per year) source: EuropePMC

Archives of surgery (Chicago, Ill. : 1960), Volume 142, Issue 7, 1 1 2007, Pages 662-667 Type-D personality and ankle brachial index as predictors of impaired quality of life and depressive symptoms in peripheral arterial disease. Aquarius AE, Denollet J, Hamming JF, Van Berge Henegouwen DP, De Vries J

Background: Patient-based outcomes, such as impaired quality of life (QOL) and depression, may adversely affect the clinical course of patients with peripheral arterial disease (PAD). Disease severity indices, including the ankle brachial index, are only partially associated with these outcomes. Objective: To examine whether individual differences in personality would predict impaired QOL and depression above and beyond PAD severity. Design: A prospective follow-up study. Setting: Vascular outpa... Abstract

Cited 17 times since 2007 (0.9 per year) source: EuropePMC

The Journal of heart valve disease, Volume 16, Issue 4, 1 1 2007, Pages 398-403 Outcome of pregnancy in women after pulmonary autograft valve replacement for congenital aortic valve disease. Yap SC, Drenthen W, Pieper PG, Moons P, Mulder BJ, Klieverik LM, Vliegen HW, van Dijk AP, Meijboom FJ, Roos-Hesselink JW, ZAHARA investigators

Background and aim of the study: The pulmonary autograft has been recommended as the valve of choice for aortic valve replacement (AVR) in young women contemplating pregnancy. However, current information on maternal and perinatal outcome of pregnancy in women with pulmonary autograft valve replacement is limited. Methods: Using a nationwide Dutch registry (CONCOR) and a local Belgian tertiary care center database, 17 women (age range: 18 to 45 years) with pulmonary autograft valve replacement w... Abstract

Cited 9 times since 2007 (0.5 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 14, Issue 4, 1 1 2007, Pages 604-612 The current status of multislice computed tomography in the diagnosis and prognosis of coronary artery disease. Schuijf JD, Jukema JW, van der Wall EE, Bax JJ

Abstract

Cited 3 times since 2007 (0.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 14, Issue 4, 1 1 2007, Pages 550-554 Prognostic implications of stress Tc-99m tetrofosmin myocardial perfusion imaging in patients with left ventricular hypertrophy. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Feringa HH, Noordzij PG, Schouten O, Poldermans D

Background: Left ventricular hypertrophy (LVH) is associated with an increased risk of cardiac death. Data on the prognostic value of myocardial perfusion imaging (MPI) in patients with LVH are limited. The aim of this study is to assess the independent value of stress technetium 99m tetrofosmin MPI in predicting the long-term mortality rate in patients with LVH. Methods and results: We studied 177 patients (mean age, 59 +/- 12 years; 134 men) with LVH by electrocardiographic criteria who underw... Abstract

Cited 9 times since 2007 (0.5 per year) source: EuropePMC

Journal of magnetic resonance imaging : JMRI, Volume 26, Issue 1, 1 1 2007, Pages 14-22 Applications of multislice computed tomography in coronary artery disease. de Roos A, Kroft LJ, Bax JJ, Geleijns J

Multislice computed tomography (MSCT) provides high accuracy for noninvasive assessment of coronary artery disease (CAD). The introduction of the latest computed tomography (CT) technology allows comprehensive evaluation of various aspects of CAD, including the coronary calcium score, coronary artery stenoses, bypass patency, and myocardial function. Other applications, such as plaque characterization, first-pass perfusion imaging, and viability imaging using delayed contrast enhancement, are st... Abstract

Cited 217 times since 2007 (11.8 per year) source: EuropePMC

Current problems in cardiology, Volume 32, Issue 7, 1 1 2007, Pages 375-410 Hibernating myocardium: diagnosis and patient outcomes. Schinkel AF, Bax JJ, Poldermans D, Elhendy A, Ferrari R, Rahimtoola SH

Approximately 50% of the patients with chronic obstructive coronary artery disease resulting in chronic contractile dysfunction have hibernating myocardium and may benefit from revascularization. This pooled analysis describes the relative merits of dobutamine echocardiography, thallium-201 and technetium-99m scintigraphy, positron emission tomography, and magnetic resonance imaging, for the diagnosis of hibernating myocardium and prediction of patient outcomes. Abstract

Cited 19 times since 2007 (1 per year) source: EuropePMC

Pharmacogenetics and genomics, Volume 17, Issue 7, 1 1 2007, Pages 473-479 The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9. Visser LE, van Schaik RH, Jan Danser AH, Hofman A, Witteman JC, van Duijn CM, Uitterlinden AG, Pols HA, Stricker BH

Objective: The aim of the present follow-up study was to investigate whether the enzyme activity of the human cytochrome P450 (CYP) 2C9 isoenzyme is associated with myocardial infarction. Methods: We investigated whether the variant alleles CYP2C9*2 and CYP2C9*3 or the use of CYP2C9 substrates or inhibitors was associated with an increased risk of myocardial infarction in 2210 men and 3534 women from the Rotterdam Study, a prospective population-based cohort study of individuals aged 55 years or... Abstract

Cited 4 times since 2007 (0.2 per year) source: EuropePMC

Nederlands tijdschrift voor geneeskunde, Volume 151, Issue 28, 1 1 2007, Pages 1561-1565 [Pregabalin in the treatment of neuropathic pain]. Biegstraaten M, van Schaik IN

Pregabalin is increasingly being used for the treatment ofneuropathic pain, often as the first-line choice. The question is, however, whether this choice is based on evidence. Seven trials have been published on the effect ofpregabalin in patients with postherpetic neuralgia and painful diabetic neuropathy. These trials more frequently report a 50% reduction in pain in pregabalin treated patients than in patients treated with placebo (number needed to treat 4.3). Dizziness and somnolence are the... Abstract

Cited 2 times since 2007 (0.1 per year) source: EuropePMC

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Volume 2, Issue 7, 1 1 2007, Pages 652-656 Pulmonary resection for metastases from colorectal cancer. van Schaik PM, Kouwenhoven EA, Bolhuis RJ, Biesma B, Bosscha K

Introduction: The lung is the most common extraabdominal site for metastases from colorectal cancer. Patients with untreated metastatic disease have a median survival of less than 10 months and a 5-year survival of less than 5%. The purpose of this study was to evaluate long-term survival in patients who underwent pulmonary resection for metastases from colorectal cancer. Methods: Between January 1990 and January 2005, 23 patients underwent 29 operations for resection of lung metastases. Results... Abstract

Cited 69 times since 2007 (3.7 per year) source: EuropePMC

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 9, Issue 4, 1 1 2007, Pages 645-651 Magnetic resonance assessment of aortic pulse wave velocity, aortic distensibility, and cardiac function in uncomplicated type 2 diabetes mellitus. van der Meer RW, Diamant M, Westenberg JJ, Doornbos J, Bax JJ, de Roos A, Lamb HJ

Background: Type 2 diabetes mellitus (DM2) may augment arterial stiffening and thereby modulates left ventricular (LV) function. Cardiovascular magnetic resonance (CMR) is well suited to assess aortic pulse wave velocity (PWV) and aortic distensibility, both markers of arterial stiffness, without the use of geometric assumptions. Furthermore, CMR is a reliable method for assessing left ventricular (LV) function. The purpose of this study was to assess LV function, PWV, and aortic distensibility... Abstract

Cited 97 times since 2007 (5.3 per year) source: EuropePMC

European heart journal, Volume 28, Issue 18, 29 5 2007, Pages 2223-2230 Impaired myocardial perfusion and perfusion reserve associated with increased coronary resistance in persistent idiopathic atrial fibrillation. Range FT, Schäfers M, Acil T, Schäfers KP, Kies P, Paul M, Hermann S, Brisse B, Breithardt G, Schober O, Wichter T

Aims: Patients with atrial fibrillation (AF) present with symptoms of myocardial ischaemia despite exclusion of coronary artery disease. A small vessel disease has been suggested. We quantified myocardial perfusion, perfusion reserve, and coronary vascular resistance (CVR) in AF patients using positron emission tomography (PET). Methods and results: Twenty-five male patients (age: 58 +/- 13 years) with persistent idiopathic AF were compared with 13 age- and risk-matched male controls (age: 56 +/... Abstract

Cited 66 times since 2007 (3.6 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 27, Issue 9, 28 4 2007, Pages 2050-2057 Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis. Hauer AD, van Puijvelde GH, Peterse N, de Vos P, van Weel V, van Wanrooij EJ, Biessen EA, Quax PH, Niethammer AG, Reisfeld RA, van Berkel TJ, Kuiper J

Objective: Vascular endothelial growth factor receptor 2 (VEGFR2)-overexpressing cells may form an interesting target for the treatment of atherosclerosis because of their involvement in processes that contribute to this disease, such as angiogenesis. Methods and results: We vaccinated mice against VEGFR2 by an orally administered DNA vaccine, comprising a plasmid, encoding murine VEGFR2, carried by live attenuated Salmonella typhimurium. This vaccine induces cellular immunity against cells that... Abstract

Cited 74 times since 2007 (4 per year) source: EuropePMC

Clinical pharmacology and therapeutics, Volume 83, Issue 2, 27 4 2007, Pages 288-292 Cytochrome P450 2C9 *2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus. Becker ML, Visser LE, Trienekens PH, Hofman A, van Schaik RH, Stricker BH

Sulfonylurea hypoglycemics are mainly metabolized by the cytochrome P450 2C9 (CYP2C9) enzyme. The CYP2C9*2 and *3 polymorphisms encode proteins with less enzymatic activity and are correlated with elevated serum levels of sulfonylurea, as demonstrated in healthy volunteers. In this study, the effect of these variants is described for patients with diabetes mellitus treated with sulfonylurea. Associations between CYP2C9 polymorphisms, prescribed doses of sulfonylurea, and change in glucose levels... Abstract

Cited 18 times since 2007 (1 per year) source: EuropePMC

Preventive veterinary medicine, Volume 82, Issue 1-2, 26 4 2007, Pages 159-165 Diagnostic validity and costs of pooled fecal samples and individual blood or fecal samples to determine the cow- and herd-status for Mycobacterium avium subsp. paratuberculosis. van Schaik G, Pradenas F M, Mella N A, Kruze V J

Two tests are used on a regular basis to detect Mycobacterium avium subsp. paratuberculosis (Map): ELISA and fecal culture. Fecal culture is considered more sensitive and specific but is costly and requires 3-4 months for results. Pooling of fecal samples of individual animals may reduce the high costs of fecal culture. The objective of the study was to investigate the diagnostic validity and costs for pooling of fecal samples in dairy farms relative to culture or an ELISA on individual samples... Abstract

Cited 53 times since 2007 (2.9 per year) source: EuropePMC

European journal of heart failure, Volume 9, Issue 8, 22 4 2007, Pages 808-813 Importance of the echocardiographic evaluation of right ventricular function in patients with AL amyloidosis. Ghio S, Perlini S, Palladini G, Marsan NA, Faggiano G, Vezzoli M, Klersy C, Campana C, Merlini G, Tavazzi L

Background: Patients with AL amyloidosis often present with signs of congestive heart failure. Aim: This study was prospectively designed to assess the significance of RV dysfunction in AL amyloidosis. Methods and results: Seventy-four patients with biopsy proven AL amyloidosis underwent a thorough echocardiographic evaluation. A tricuspid annular plane systolic excursion (TAPSE) Abstract

Cited 1 times since 2007 (0.1 per year) source: EuropePMC

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 34, Issue 3, 19 3 2007, Pages 378 The Oslo Balloon Angioplasty versus Conservative Treatment Study (OBACT) - The 2-years results of a single centre, prospective, randomised study in patients with intermittent claudication. Breek JC, De Vries J, Hamming JF

Abstract

Cited 31 times since 2007 (1.7 per year) source: EuropePMC

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Volume 21, Issue 12, 19 3 2007, Pages 3369-3379 Fibroblasts from human postmyocardial infarction scars acquire properties of cardiomyocytes after transduction with a recombinant myocardin gene. van Tuyn J, Pijnappels DA, de Vries AA, de Vries I, van der Velde-van Dijke I, Knaän-Shanzer S, van der Laarse A, Schalij MJ, Atsma DE

Myocardial scar formation impairs heart function by inducing cardiac remodeling, decreasing myocardial compliance, and compromising normal electrical conduction. Conversion of myocardial scar fibroblasts (MSFs) into (functional) cardiomyocytes may be an effective alternative treatment to limit loss of cardiac performance after myocardial injury. In this study, we investigated whether the phenotype of MSFs can be modified by gene transfer into cells with properties of cardiomyocytes. To this end,... Abstract

Cited 206 times since 2007 (11.2 per year) source: EuropePMC

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 48, Issue 7, 15 3 2007, Pages 1104-1111 Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT? Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, van der Wall EE, Schalij MJ, Garcia EV, Bax JJ

Unlabelled: Cardiac resynchronization therapy (CRT) is now a well-recognized therapeutic option for patients with end-stage heart failure. However, not all patients respond to CRT, and, therefore, preimplantation identification of responders is desirable. The aim of the present study was to investigate whether the degree of left ventricular (LV) dyssynchrony, as assessed with phase analysis from gated myocardial perfusion SPECT (GMPS), can predict which patients will respond to CRT. Methods: For... Abstract