9543 results
Cited 4 times since 2005 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 22, Issue 1, 10 2 2005, Pages 107-109
Noninvasive visualization of the coronary arteries with multi-slice computed tomography; influence of heart rate on diagnostic accuracy.
Henneman MM, Bax JJ, Schuijf JD, van der Wall EE
Abstract
Tijdschrift voor gerontologie en geriatrie,
Volume 36, Issue 6, 1 1 2005, Pages 263-266
Redenen voor non-respons van oudere Turkse, Marokkaanse en Nederlandse huisartspatiënten op een schriftelijke Nederlandstalige depressievragenlijst.
Simsek V, van der Kooij K, van Schaik D, de Haan M, van Marwijk H, van Hout H
Abstract
Cited 23 times since 2005 (1.2 per year)
source: EuropePMC
European journal of cancer (Oxford, England : 1990),
Volume 42, Issue 2, 1 1 2005, Pages 141-148
Genotyping and phenotyping cytochrome P450: perspectives for cancer treatment.
Mathijssen RH, van Schaik RH
As most anticancer agents display a narrow therapeutic window, patients may be susceptible to (extreme) toxicities or a lowered therapeutic outcome if not dosed adequately. Therefore, it is important to study factors which affect the pharmacokinetics and pharmacodynamics of these drugs. Among these, the contribution of genetic variation in drug metabolizing enzymes on the metabolism of anticancer agents has gathered interest, as it may potentially explain a substantial amount of interpatient var...
Abstract
Cited 43 times since 2005 (2.2 per year)
source: EuropePMC
Investigational new drugs,
Volume 23, Issue 6, 1 1 2005, Pages 513-522
Cancer treatment and pharmacogenetics of cytochrome P450 enzymes.
van Schaik RH
For the treatment of cancer, the window between drug toxicity and suboptimal therapy is often narrow. Interindividual variation in drug metabolism therefore complicates therapy. Genetic polymorphisms in phase I and phase II enzymes may explain part of the observed interindividual variation in pharmacokinetics and pharmacodynamics of anticancer drugs. The cytochrome P450 superfamily is involved in many drug metabolizing reactions. Information on variant alleles for the different isoenzymes of thi...
Abstract
Cited 54 times since 2005 (2.7 per year)
source: EuropePMC
Human molecular genetics,
Volume 15, Issue 2, 1 1 2005, Pages 213-221
Human mesenchymal stem cells ectopically expressing full-length dystrophin can complement Duchenne muscular dystrophy myotubes by cell fusion.
Gonçalves MA, de Vries AA, Holkers M, van de Watering MJ, van der Velde I, van Nierop GP, Valerio D, Knaän-Shanzer S
Duchenne muscular dystrophy (DMD) is the most prevalent inheritable muscle disease. It is caused by mutations in the approximately 2.5-megabase dystrophin (Dys) encoding gene. Therapeutic attempts at DMD have relied on injection of allogeneic Dys-positive myoblasts. The immune rejection of these cells and their limited availability have prompted the search for alternative therapies and sources of myogenic cells. Stem cell-based gene therapy aims to restore tissue function by the transplantation...
Abstract
Cited 1 times since 2005 (0.1 per year)
source: EuropePMC
Tijdschrift voor gerontologie en geriatrie,
Volume 36, Issue 6, 1 1 2005, Pages 243-246
[Reasons for non-response of elderly Turkish, Moroccan and Dutch general practice patients on a postal depression screening].
Simsek V, van der Kooij K, van Schaik D, de Haan M, van Marwijk H, van Houte H
Background: Depression screening can improve identification and subsequent treatment of depression in general practice. Response of Turkish and Moroccan elderly is unknown. Objectives: (1) To assess the response of elderly Turkish and Moroccan general practice patients on a postal depression screening. (2) To trace reasons for non-response. Method: At 14 different primary care centres, elderly (55+) were screened with GDS-15. Turkish and Moroccan elderly were telephonically and house-to-house ap...
Abstract
Cited 28 times since 2005 (1.4 per year)
source: EuropePMC
Heart rhythm,
Volume 2, Issue 12, 1 1 2005, Pages 1286-1293
Dispersion of repolarization in cardiac resynchronization therapy.
van Huysduynen BH, Swenne CA, Bax JJ, Bleeker GB, Draisma HH, van Erven L, Molhoek SG, van de Vooren H, van der Wall EE, Schalij MJ
Background: Proarrhythmic effects of cardiac resynchronization therapy (CRT) as a result of increased transmural dispersion of repolarization (TDR) induced by left ventricular (LV) epicardial pacing in a subset of vulnerable patients have been reported. The possibility of identifying these patients by ECG repolarization indices has been suggested. Objectives: The purpose of this study was to test whether repolarization indices on the ECG can be used to measure dispersion of repolarization during...
Abstract
Cited 8 times since 2005 (0.4 per year)
source: EuropePMC
The American journal of medicine,
Volume 118, Issue 12, 1 1 2005, Pages 1381-1386
Pacemaker stress echocardiography predicts cardiac events in patients with permanent pacemaker.
Biagini E, Schinkel AF, Elhendy A, Bax JJ, Rizzello V, van Domburg RT, Krenning BJ, Schouten O, Branzi A, Rocchi G, Simoons ML, Poldermans D
Purpose: Noninvasive pacemaker stress echocardiography is a newly introduced method for the diagnosis of coronary artery disease in patients with a permanent pacemaker. The prognostic value of pacemaker stress echocardiography has not been studied. Subjects and methods: We studied 136 patients (mean age 64+/-12 years) with a permanent pacemaker who underwent pacemaker stress echocardiography for evaluation of coronary artery disease. All patients underwent pacemaker stress echocardiography by ex...
Abstract
Cited 14 times since 2005 (0.7 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 46, Issue 12, 1 1 2005, Pages 2003-2008
Risk stratification of patients with angina pectoris by stress 99mTc-tetrofosmin myocardial perfusion imaging.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Huurman A, Feringa HH, Poldermans D
Unlabelled: Angina pectoris is a major symptom associated with myocardial ischemia. The aim of this study was to find whether stress myocardial perfusion imaging can independently predict mortality in patients with angina. Methods: We studied 455 patients with stable angina pectoris by exercise or dobutamine stress (99m)Tc-tetrofosmin myocardial perfusion tomographic imaging. An abnormal finding was defined as a reversible or fixed perfusion abnormality. The endpoint during follow-up was death f...
Abstract
Cited 27 times since 2005 (1.4 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 28, Issue 12, 1 1 2005, Pages 1271-1275
Does a gender difference in response to cardiac resynchronization therapy exist?
Bleeker GB, Schalij MJ, Boersma E, Steendijk P, van der Wall EE, Bax JJ
Background: Cardiac resynchronization therapy (CRT) has a beneficial effect on clinical symptoms, exercise capacity, and systolic left ventricular (LV) performance in patients with heart failure. The aim of the current study was to evaluate whether a gender difference exists in response to CRT. Methods: Consecutive patients with end-stage heart failure (New York Heart Association, NYHA, class III-IV), LV ejection fraction (LVEF) < or =35%, QRS duration >120 ms, and left bundle branch block...
Abstract
Cited 14 times since 2005 (0.7 per year)
source: EuropePMC
The journal of physical chemistry. B,
Volume 109, Issue 50, 1 1 2005, Pages 23993-24001
Destructive adsorption of CCl4 over lanthanum-based solids: linking activity to acid-base properties.
van der Heijden AW, Bellière V, Alonso LE, Daturi M, Manoilova OV, Weckhuysen BM
The relative activities of a low-surface crystalline and high-surface amorphous LaOCl, further denoted as S1 and S2, have been compared for the destructive adsorption of CCl4. It was found that the intrinsic activity of S2 is higher than that of S1. Both samples were characterized with X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), N2-physisorption, and Raman and infrared (IR) spectroscopy. IR was used in combination with CO2, CO, and methanol as probe molecules. The CO2 experi...
Abstract
Cited 129 times since 2005 (6.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 12, 1 1 2005, Pages 2168-2182
Cardiac resynchronization therapy: Part 2--issues during and after device implantation and unresolved questions.
Bax JJ, Abraham T, Barold SS, Breithardt OA, Fung JW, Garrigue S, Gorcsan J, Hayes DL, Kass DA, Knuuti J, Leclercq C, Linde C, Mark DB, Monaghan MJ, Nihoyannopoulos P, Schalij MJ, Stellbrink C, Yu CM
Encouraged by the clinical success of cardiac resynchronization therapy (CRT), the implantation rate has increased exponentially, although several limitations and unresolved issues of CRT have been identified. This review concerns issues that are encountered during implantation of CRT devices, including the role of electroanatomical mapping, whether CRT implantation should be accompanied by simultaneous atrioventricular nodal ablation in patients with atrial fibrillation, procedural complication...
Abstract
Cited 79 times since 2005 (4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 12, 1 1 2005, Pages 2264-2269
Left ventricular dyssynchrony predicts right ventricular remodeling after cardiac resynchronization therapy.
Bleeker GB, Schalij MJ, Nihoyannopoulos P, Steendijk P, Molhoek SG, van Erven L, Bootsma M, Holman ER, van der Wall EE, Bax JJ
Objectives: The purpose of this research was to evaluate right ventricular (RV) remodeling after six months of cardiac resynchronization therapy (CRT). Background: Cardiac resynchronization therapy is beneficial in patients with end-stage heart failure. The effect of CRT on RV size is currently unknown. Accordingly, the effects of CRT on RV size, severity of tricuspid regurgitation, and pulmonary artery pressure were evaluated. Methods: Fifty-six consecutive patients with end-stage heart failure...
Abstract
Cited 295 times since 2005 (14.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 12, 1 1 2005, Pages 2153-2167
Cardiac resynchronization therapy: Part 1--issues before device implantation.
Bax JJ, Abraham T, Barold SS, Breithardt OA, Fung JW, Garrigue S, Gorcsan J, Hayes DL, Kass DA, Knuuti J, Leclercq C, Linde C, Mark DB, Monaghan MJ, Nihoyannopoulos P, Schalij MJ, Stellbrink C, Yu CM
Cardiac resynchronization therapy (CRT) has been used extensively over the last years in the therapeutic management of patients with end-stage heart failure. Data from 4,017 patients have been published in eight large, randomized trials on CRT. Improvement in clinical end points (symptoms, exercise capacity, quality of life) and echocardiographic end points (systolic function, left ventricular size, mitral regurgitation) have been reported after CRT, with a reduction in hospitalizations for deco...
Abstract
Cited 71 times since 2005 (3.6 per year)
source: EuropePMC
Radiology,
Volume 237, Issue 3, 1 1 2005, Pages 868-871
Corrected tetralogy of Fallot: delayed enhancement in right ventricular outflow tract.
Oosterhof T, Mulder BJ, Vliegen HW, de Roos A
Purpose: To evaluate retrospectively the presence of fibrosis and largest diameter of the right ventricular outflow tract (RVOT) by using delayed enhancement magnetic resonance (MR) imaging in patients who had undergone initial correction for tetralogy of Fallot. Materials and methods: MR imaging was performed in 24 consecutive patients (16 male, eight female; mean age, 25 years; age range, 13-47 years) with corrected tetralogy of Fallot. The study protocol was approved by the local ethics commi...
Abstract
Nederlands tijdschrift voor geneeskunde,
Volume 149, Issue 50, 1 1 2005, Pages 2773-2774
[The availability of only one statin is inadequate].
Jukema JW
When looking at the history of the prescription of a new class of drugs e.g. the statin, it is clear that for optimal use with regard to efficacy, areas of indication and safety, the continuous development of new compounds within this class was very advantageous. Competition between compounds is essential for providing best patient care. Thus the availability of only one statin was and continues to be inadequate for this purpose.
Abstract
Cited 58 times since 2005 (2.9 per year)
source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology,
Volume 19, Issue 14, 1 1 2005, Pages 1998-2004
Tumor necrosis factor-alpha plays an important role in restenosis development.
Monraats PS, Pires NM, Schepers A, Agema WR, Boesten LS, de Vries MR, Zwinderman AH, de Maat MP, Doevendans PA, de Winter RJ, Tio RA, Waltenberger J, 't Hart LM, Frants RR, Quax PH, van Vlijmen BJ, Havekes LM, van der Laarse A, van der Wall EE, Jukema JW
Genetic factors appear to be important in the restenotic process after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis. TNFalpha, a key regulator of inflammatory responses, may exert critical influence on the development of restenosis after PCI. The GENetic DEterminants of Restenosis (GENDER) project included 3104 patients who underwent a successful PCI. Systematic genotyping for six polymorphisms in the TNFalpha gene was performed. The role o...
Abstract
Cited 18 times since 2005 (0.9 per year)
source: EuropePMC
Heart rhythm,
Volume 2, Issue 12, 1 1 2005, Pages 1365-1368
Syndactyly and long QT syndrome (CaV1.2 missense mutation G406R) is associated with hypertrophic cardiomyopathy.
Lo-A-Njoe SM, Wilde AA, van Erven L, Blom NA
Abstract
Cited 3 times since 2005 (0.2 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 149, Issue 51, 1 1 2005, Pages 2837-2840
[Percutaneous coronary intervention with stent placement versus bypass operation in symptomatic multiple-vessel disease; lessons from an observational study].
van der Hoeven BL, Schalij MJ, van der Wall EE
In a large observational study comparing percutaneous coronary intervention (PCI) using stent implantation with coronary-artery bypass grafting (CABG), 3-year survival was better after CABG than after PCI with stenting. This was particularly true in patients with triple-vessel disease, and for patients with two-vessel disease with involvement ofthe proximal left anterior descending artery (LAD). Potential explanations for this finding are that with CABG 'future' culprit lesions are byp...
Abstract
Cited 198 times since 2005 (9.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 97, Issue 2, 28 4 2005, Pages 260-263
Clinical versus echocardiographic parameters to assess response to cardiac resynchronization therapy.
Bleeker GB, Bax JJ, Fung JW, van der Wall EE, Zhang Q, Schalij MJ, Chan JY, Yu CM
Currently, a clear definition of response to cardiac resynchronization therapy (CRT) is still lacking, and clinical and echocardiographic end points are used. It is also unclear whether patients with clinical responses also improve in echocardiographic end points (and vice versa). To better understand and define response to CRT, the relation between improvement in clinical and echocardiographic parameters was evaluated in 144 patients.
Abstract
