6128 results
Cited 42 times since 2007 (2.3 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 93, Issue 8, 20 3 2007, Pages 922-927
Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries.
Pires NM, Eefting D, de Vries MR, Quax PH, Jukema JW
Background: Drug-eluting stents (DES) have been introduced successfully in clinical practice to prevent post-angioplasty restenosis. Nevertheless, concerns about the safety of DES still exist. Objective: To investigate the vascular pathology and transcriptional responses to sirolimus and paclitaxel in a murine model for restenosis on underlying diseased atherosclerotic arteries. Methods: Atherosclerotic lesions were induced by placement of a perivascular cuff around the femoral artery of hyperch...
Abstract
Cited 182 times since 2007 (10.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 49, Issue 17, 16 3 2007, Pages 1763-1769
A clinical randomized trial to evaluate the safety of a noninvasive approach in high-risk patients undergoing major vascular surgery: the DECREASE-V Pilot Study.
Poldermans D, Schouten O, Vidakovic R, Bax JJ, Thomson IR, Hoeks SE, Feringa HH, Dunkelgrün M, de Jaegere P, Maat A, van Sambeek MR, Kertai MD, Boersma E, DECREASE Study Group
Objectives: The purpose of this research was to perform a feasibility study of prophylactic coronary revascularization in patients with preoperative extensive stress-induced ischemia. Background: Prophylactic coronary revascularization in vascular surgery patients with coronary artery disease does not improve postoperative outcome. If a beneficial effect is to be expected, then at least those with extensive coronary artery disease should benefit from this strategy. Methods: One thousand eight hu...
Abstract
Cited 3 times since 2007 (0.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 99, Issue 11, 16 3 2007, Pages 1555-1559
Value of myocardial viability estimation using dobutamine stress echocardiography in assessing risk preoperatively before noncardiac vascular surgery in patients with left ventricular ejection fraction <35%.
Karagiannis SE, Feringa HH, Vidakovic R, van Domburg R, Schouten O, Bax JJ, Karatasakis G, Cokkinos DV, Poldermans D
Patients with heart failure (HF) scheduled for vascular surgery have an increased risk of adverse postoperative outcome, and stratification usually depends on dichotomous risk factors. A quantitative prognostic model for patients with HF was developed using wall motion patterns during dobutamine stress echocardiography (DSE). A total of 295 consecutive patients (mean age 67 +/- 12 years) with ejection fraction < or =35% were studied. During DSE, wall motion patterns of dysfunctional segments...
Abstract
Cited 3 times since 2007 (0.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 32, Issue 2, 12 2 2007, Pages 274-280
New ultrasonic radiation reduces cerebral emboli during extracorporeal circulation.
Sauren LD, la Meir M, Palmen M, Severdija E, van der Veen FH, Mess WH, Maessen JG
Objective: Cardiac surgery is associated with intraoperative cerebral emboli, which can result in postoperative neurological complications. A new ultrasonic transducer (EmBlocker) can be positioned on the ascending aorta and activation of the EmBlocker is expected to divert emboli to the descending aorta, thereby decreasing emboli in the cerebral arteries. In this preliminary animal study, safety and efficiency of this technology were examined. Methods: In 14 pigs (+/-70 kg), a median sternotomy...
Abstract
Cited 32 times since 2007 (1.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 99, Issue 11, 12 2 2007, Pages 1485-1490
Relation of body mass index to outcome in patients with known or suspected coronary artery disease.
Galal W, van Domburg RT, Feringa HH, Schouten O, Elhendy A, Bax JJ, Awara AM, Klein J, Poldermans D
Increased body mass index (BMI), a parameter of total body fat content, is associated with an increased mortality in the general population. However, recent studies have shown a paradoxic relation between BMI and mortality in specific patient populations. This study investigated the association of BMI with long-term mortality in patients with known or suspected coronary artery disease. In a retrospective cohort study of 5,950 patients (mean age 61 +/- 13 years; 67% men), BMI, cardiovascular risk...
Abstract
Cited 11 times since 2007 (0.6 per year)
source: EuropePMC
International journal of cardiology,
Volume 124, Issue 3, 11 2 2007, Pages 301-306
Pulmonary valve replacement in tetralogy of Fallot improves the repolarization.
Hooft van Huysduynen B, Henkens IR, Swenne CA, Oosterhof T, Draisma HH, Maan AC, Hazekamp MG, de Roos A, Schalij MJ, van der Wall EE, Vliegen HW
Objective: To assess the effect of pulmonary valve replacement (PVR) on the repolarization of patients with tetralogy of Fallot. Background: Pulmonary valve regurgitation may cause right ventricular failure in adult patients with Fallot's tetralogy. In these patients, prolonged depolarization and disturbed repolarization are associated with ventricular arrhythmias and sudden cardiac death. Methods: Thirty Fallot patients (age 32+/-9 years, 19 male) eligible for PVR were studied with cardiac...
Abstract
Cited 84 times since 2007 (4.7 per year)
source: EuropePMC
American journal of epidemiology,
Volume 165, Issue 12, 9 2 2007, Pages 1356-1363
Aging, retirement, and changes in physical activity: prospective cohort findings from the GLOBE study.
Slingerland AS, van Lenthe FJ, Jukema JW, Kamphuis CB, Looman C, Giskes K, Huisman M, Narayan KM, Mackenbach JP, Brug J
There is increased recognition that determinants of health should be investigated in a life-course perspective. Retirement is a major transition in the life course and offers opportunities for changes in physical activity that may improve health in the aging population. The authors examined the effect of retirement on changes in physical activity in the GLOBE Study, a prospective cohort study known by the Dutch acronym for "Health and Living Conditions of the Population of Eindhoven and sur...
Abstract
Cited 33 times since 2007 (1.8 per year)
source: EuropePMC
Journal of virological methods,
Volume 143, Issue 2, 8 2 2007, Pages 169-174
An improved plaque reduction virus neutralization assay for human metapneumovirus.
de Graaf M, Herfst S, Schrauwen EJ, van den Hoogen BG, Osterhaus AD, Fouchier RA
Virus-neutralizing antibodies against human metapneumovirus (hMPV) have been shown to be important indicators for protection in experimental animal models. An improved plaque reduction virus neutralization assay to detect hMPV-specific neutralizing antibodies was designed using two prototype recombinant hMPV strains expressing green fluorescent protein (GFP). These prototypes represented each of the main antigenic variants of hMPV, because antigenic variability could have implications for vaccin...
Abstract
Cited 134 times since 2007 (7.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 49, Issue 16, 5 1 2007, Pages 1708-1714
Phase analysis of gated myocardial perfusion single-photon emission computed tomography compared with tissue Doppler imaging for the assessment of left ventricular dyssynchrony.
Henneman MM, Chen J, Ypenburg C, Dibbets P, Bleeker GB, Boersma E, Stokkel MP, van der Wall EE, Garcia EV, Bax JJ
Objectives: The purpose of this study was to compare left ventricular (LV) dyssynchrony assessment by gated myocardial perfusion single-photon emission computed tomography (SPECT) (GMPS) and tissue Doppler imaging (TDI). Background: Recently, it has been suggested that LV dyssynchrony is an important predictor of response to cardiac resynchronization therapy (CRT); dyssynchrony is predominantly assessed by TDI with echocardiography. Information on LV dyssynchrony can also be provided by GMPS wit...
Abstract
European heart journal,
Volume 28, Issue 8, 4 1 2007, Pages 922-923
Monitoring of therapeutic effect in heart failure patients: a clinical application of 123I MIBG imaging?
Henneman MM, Bax JJ, van der Wall EE
Abstract
Cited 5 times since 2007 (0.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 124, Issue 2, 3 1 2007, Pages 166-171
Dexamethasone-eluting stents for the prevention of in-stent restenosis: evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients.
van der Hoeven BL, Pires NM, Warda HM, Putter H, Quax PH, Schalij MJ, Jukema JW
Unlabelled: Diabetes mellitus (DM) is a strong predictor of in-stent restenosis. This may be due to a higher level of vascular inflammation. We hypothesized that diabetic patients will benefit from dexamethasone-eluting stents, since local inflammation and consequently neointimal growth are suppressed and no systemic side effects will occur. Methods: 21 consecutive patients with DM with 32 lesions were treated with dexamethasone-eluting stents. Excluded were patients with triple vessel disease,...
Abstract
Cited 81 times since 2007 (4.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 49, Issue 15, 2 1 2007, Pages 1660-1665
Reduced aortic elasticity and dilatation are associated with aortic regurgitation and left ventricular hypertrophy in nonstenotic bicuspid aortic valve patients.
Grotenhuis HB, Ottenkamp J, Westenberg JJM, Bax JJ, Kroft LJM, de Roos A
Objectives: This study sought to assess elasticity and dimensions of the aorta and their impact on aortic valve competence and left ventricular (LV) function in patients with a nonstenotic bicuspid aortic valve (BAV). Background: Intrinsic pathology of the aortic wall is a possible explanation for reduced aortic elasticity and aortic dilatation in patients with BAVs, even in the absence of a stenotic aortic valve. The relationship between aortic wall elasticity, aortic dimensions, aortic valve c...
Abstract
Cited 7 times since 2007 (0.4 per year)
source: EuropePMC
Journal of cardiac failure,
Volume 13, Issue 3, 1 1 2007, Pages 178-183
Clinical efficacy of surgical heart failure therapy by ventricular restoration and restrictive mitral annuloplasty.
Tulner SA, Steendijk P, Klautz RJ, Tops L, Bax JJ, Versteegh MI, Verwey HF, Schalij MJ, van der Wall EE, Dion RA
Background: Treatment of heart failure by advanced surgical procedures such as ventricular restoration (SVR) and restrictive mitral annuloplasty (RMA) is increasingly applied. We studied clinical efficacy of heart failure surgery in patients with severe heart failure. Methods and results: Thirty-three patients (New York Heart Association (NYHA) class III/IV, left ventricular ejection fraction < or =35%) were included. Patients with moderate to severe mitral regurgitation underwent RMA (85%) a...
Abstract
Cited 33 times since 2007 (1.8 per year)
source: EuropePMC
The Journal of general virology,
Volume 88, Issue Pt 4, 1 1 2007, Pages 1251-1259
Experimental infection of macaques with human metapneumovirus induces transient protective immunity.
van den Hoogen BG, Herfst S, de Graaf M, Sprong L, van Lavieren R, van Amerongen G, Yüksel S, Fouchier RAM, Osterhaus ADME, de Swart RL
Human metapneumovirus (hMPV), a member of the family Paramyxoviridae, is a causative agent of acute respiratory-tract illness. Two main hMPV lineages circulate worldwide and reinfections occur frequently. It is unclear what level of protection is induced by natural hMPV infection, what the durability of this protection is and whether it differs for reinfection with homologous or heterologous viruses. Here, protective immunity in cynomolgus macaques at different time points after inoculation with...
Abstract
Cited 28 times since 2007 (1.6 per year)
source: EuropePMC
Annals of the New York Academy of Sciences,
Volume 1100, 1 1 2007, Pages 189-198
Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study.
Trompet S, Pons D, DE Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen EL, Buckley BM, Ford I, Hyland M, Gaw A, Macfarlane PW, Packard CJ, Norrie J, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, Jukema JW
Proinflammatory cytokines, like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), are implicated in the development of atherosclerosis. The role of anti-inflammatory cytokines, like IL-10, is largely unknown. We investigated the association of four single nucleotide polymorphisms (SNPs) in the promoter region of the IL-10 gene (4259AG, -1082GA, -592CA, and -2849GA), with coronary and cerebrovascular disease in participants of the PROspective Study of Pravastatin in the Elderly at...
Abstract
Cited 3 times since 2007 (0.2 per year)
source: EuropePMC
International journal of pediatric otorhinolaryngology,
Volume 71, Issue 6, 26 4 2007, Pages 857-861
Immunohistochemical assesment of heat shock protein 70 in adenoid tissue.
Aktepe F, Sahin O, Dilek H, Yilmaz D, Kahveci O, Derekoy S
Objectives: To evaluate the expression of heat shock protein 70 (HSP70) and its relation to histopathologic parameters in adenoid hypertrophy and hyperplasia. In addition, HSP70 expression in adenoid tissue was compared with in adult and childhood. Methods: Paraffin-embedded adenoid tissue sections were obtained from 19 childhood and 15 adult patients. Expression of HSP70 was evaluated by immunohistochemical staining using anti-HSP70 monoclonal antibody and correlated with histopathologic parame...
Abstract
Cited 66 times since 2007 (3.7 per year)
source: EuropePMC
American journal of respiratory and critical care medicine,
Volume 176, Issue 2, 22 4 2007, Pages 121-128
Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease.
Slats AM, Janssen K, van Schadewijk A, van der Plas DT, Schot R, van den Aardweg JG, de Jongste JC, Hiemstra PS, Mauad T, Rabe KF, Sterk PJ
Rationale: Deep inspirations provide physiologic protection against airway narrowing in healthy subjects, which is impaired in asthma and chronic obstructive pulmonary disease (COPD). Airway inflammation has been suggested to alter airway mechanics during deep inspiration. Objectives: We tested the hypothesis that the number of bronchial inflammatory cells is related to deep inspiration-induced bronchodilation in asthma and COPD. Methods: In a cross-sectional study, three modified methacholine c...
Abstract
Cited 10 times since 2007 (0.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 99, Issue 9, 15 3 2007, Pages 1193-1195
Prognostic significance of myocardial ischemia during dobutamine stress echocardiography in asymptomatic patients with diabetes mellitus and no prior history of coronary events.
Sozzi FB, Elhendy A, Rizzello V, Biagini E, van Domburg RT, Schinkel AF, Bax JJ, Vourvouri E, Danzi GB, Poldermans D
The prognostic significance of myocardial ischemia assessed by dobutamine stress echocardiography in asymptomatic patients with diabetes mellitus who have no previous coronary artery disease remains unclear. We assessed the value of dobutamine stress echocardiography for risk stratification in 161 asymptomatic patients with type 2 diabetes (mean 62 +/- 12 years of age; 96 men) who had no previous myocardial infarction or revascularization. End point during follow-up was hard cardiac events (card...
Abstract
Cited 61 times since 2007 (3.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 27, Issue 6, 15 3 2007, Pages 1426-1432
Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia.
van Weel V, Seghers L, de Vries MR, Kuiper EJ, Schlingemann RO, Bajema IM, Lindeman JH, Delis-van Diemen PM, van Hinsbergh VW, van Bockel JH, Quax PH
Objective: Vascular endothelial growth factor (VEGF)-induced stromal cell-derived factor-1 (SDF-1) has been implicated in angiogenesis in ischemic tissues by recruitment of CXCR4-positive bone marrow-derived circulating cells with paracrine functions in preclinical models. Here, evidence for this is provided in patients with peripheral artery disease. Methods and results: Expression patterns of VEGF, SDF-1, and CXCR4 were studied in amputated limbs of 16 patients. VEGF-A was expressed in vascula...
Abstract
Cited 53 times since 2007 (2.9 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 45, Issue 5, 13 2 2007, Pages 936-943
The effect of intensified lipid-lowering therapy on long-term prognosis in patients with peripheral arterial disease.
Feringa HH, Karagiannis SE, van Waning VH, Boersma E, Schouten O, Bax JJ, Poldermans D
Background: The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are associated with improved outcome in patients with peripheral arterial disease. Statins may also have beneficial properties beyond their lipid-lowering effect. Methods: A prospective, observational cohort study was conducted at a university hospital from 1990 to 2005 to examine whether higher doses of statins and lower low-density lipoprotein (LDL) cholesterol levels are both independently associated with imp...
Abstract
