Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6128 results
Cited 63 times since 2021 (17.6 per year) source: EuropePMC
The Science of the total environment, Volume 799, 4 1 2021, Pages 149456 Droplet digital RT-PCR to detect SARS-CoV-2 signature mutations of variants of concern in wastewater. Heijnen L, Elsinga G, de Graaf M, Molenkamp R, Koopmans MPG, Medema G
Wastewater surveillance has shown to be a valuable and efficient tool to obtain information about the trends of COVID-19 in the community. Since the recent emergence of new variants, associated with increased transmissibility and/or antibody escape (variants of concern), there is an urgent need for methods that enable specific and timely detection and quantification of the occurrence of these variants in the community. In this study, we demonstrate the use of RT-ddPCR on wastewater samples for s... Abstract
Cited 5 times since 2021 (1.4 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 8, Issue 8, 4 1 2021, Pages 93 Applicability of the Leiden Convention and the Lipton Classification in Patients with a Single Coronary Artery in the Setting of Congenital Heart Disease. Katekaru-Tokeshi DI, Jiménez-Santos M, Koppel CJ, Vliegen HW, Díaz-Zamudio M, Castillo-Castellón F, Jongbloed MRM, Kimura-Hayama E
In single coronary artery (SCA) anatomy, all coronary tributaries arise from a single ostium, providing perfusion to the entire myocardium. Coronary classification systems can facilitate the description of SCA anatomy. Aim: Evaluation of the applicability of Lipton classification and the Leiden Convention coronary coding system in SCA. Methods: All patients (n = 6209) who underwent computed tomography (CT) scanning between 2014 and 2018 were retrospectively examined for the presence of SCA and c... Abstract
Cited 1 times since 2021 (0.3 per year) source: EuropePMC
Omega, Volume 87, Issue 3, 3 1 2021, Pages 999-1016 A Phenomenological Analysis of Experiences and Practices of Nurses Providing Palliative and End of Life Care. Uzelli Yilmaz D, Yilmaz D, Duzgun G, Akin E
The aim of this study was to describe the experiences and practices of nurses providing palliative and end of life care. The study was conducted in the palliative care unit of a territory hospital in Turkey. The sample consisted of 11 nurses who had been working as palliative care nurses for at least one year. The face to face interview method was used to collect data, with a semi-structured in-depth individual interview. 5 main themes and 24 sub-themes were emerged in relation to the experience... Abstract
Cited 5 times since 2021 (1.4 per year) source: EuropePMC
Obesity (Silver Spring, Md.), Volume 29, Issue 9, 2 1 2021, Pages 1439-1444 Microvascular differences in individuals with obesity at risk of developing cardiovascular disease. van der Velden AIM, van den Berg BM, van den Berg BM, de Mutsert R, van der Vlag J, Jukema JW, Rosendaal FR, Rabelink TJ, Vink H
Objective: This study aimed to investigate microvascular differences in individuals with obesity at risk for developing cardiovascular disease. Methods: In this cross-sectional Netherlands Epidemiology of Obesity study, participant sublingual microcirculation was assessed with a newly developed GlycoCheck software (Microvascular Health Solutions Inc., Salt Lake City, Utah), which integrates red blood cell velocity within the smallest capillaries (4-7 µm) and feed vessels (>10 µm). Framingham... Abstract
Cited 41 times since 2021 (11.5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 78, Issue 5, 1 1 2021, Pages 421-433 Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol. Schwartz GG, Szarek M, Bittner VA, Diaz R, Goodman SG, Jukema JW, Landmesser U, López-Jaramillo P, Manvelian G, Pordy R, Scemama M, Sinnaeve PR, White HD, Gabriel Steg P, ODYSSEY Outcomes Committees and Investigators
Background: Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk. Objectives: In a post hoc analysis of the ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Synd... Abstract
Cited 1 times since 2021 (0.3 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 23, Issue 8, 1 1 2021, Pages 1275-1284 Myocardial calcification is associated with endocardial ablation failure of post-myocardial infarction ventricular tachycardia. de Riva M, Naruse Y, Ebert M, Watanabe M, Scholte AJ, Wijnmaalen AP, Trines SA, Schalij MJ, Montero-Cabezas JM, Zeppenfeld K
Aims: In patients with post-myocardial infarction (post-MI) ventricular tachycardia (VT), the presence of myocardial calcification (MC) may prevent heating of a subepicardial VT substrate contributing to endocardial ablation failure. The aims of this study were to assess the prevalence of MC in patients with post-MI VT and evaluate the impact of MC on outcome after endocardial ablation. Methods and results: In 158 patients, the presence of MC was retrospectively assessed on fluoroscopy recording... Abstract
Cited 48 times since 2021 (13.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 78, Issue 7, 1 1 2021, Pages 713-736 Coronary Computed Tomographic Angiography for Complete Assessment of Coronary Artery Disease: JACC State-of-the-Art Review. Serruys PW, Hara H, Garg S, Kawashima H, Nørgaard BL, Dweck MR, Bax JJ, Knuuti J, Nieman K, Leipsic JA, Mushtaq S, Andreini D, Onuma Y
Coronary computed tomography angiography (CTA) has shown great technological improvements over the last 2 decades. High accuracy of CTA in detecting significant coronary stenosis has promoted CTA as a substitute for conventional invasive coronary angiography in patients with suspected coronary artery disease. In patients with coronary stenosis, CTA-derived physiological assessment is surrogate for intracoronary pressure and velocity wires, and renders possible decision-making about revasculariza... Abstract
Cited 15 times since 2021 (4.2 per year) source: EuropePMC
Open heart, Volume 8, Issue 2, 1 1 2021, Pages e001681 Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe. Williams MC, Shaw L, Hirschfeld CB, Maurovich-Horvat P, Nørgaard BL, Pontone G, Jimenez-Heffernan A, Sinitsyn V, Sergienko V, Ansheles A, Bax JJ, Buechel R, Milan E, Slart RHJA, Nicol E, Bucciarelli-Ducci C, Pynda Y, Better N, Cerci R, Dorbala S, Raggi P, Villines TC, Vitola J, Malkovskiy E, Goebel B, Cohen Y, Randazzo M, Pascual TNB, Dondi M, Paez D, Einstein AJ, INCAPS COVID Investigators Group
Objectives: We aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe. Methods: The online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries. Results: Centres in Northern and Southern Europe were more li... Abstract
Cited 5 times since 2021 (1.4 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 22, Issue 9, 1 1 2021, Pages 1072-1082 Effects of chronic kidney disease and declining renal function on coronary atherosclerotic plaque progression: a PARADIGM substudy. Huang AL, Leipsic JA, Zekry SB, Sellers S, Ahmadi AA, Blanke P, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Shin S, Choi JH, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Chang HJ
Aims: To investigate the change in atherosclerotic plaque volume in patients with chronic kidney disease (CKD) and declining renal function, using coronary computed tomography angiography (CCTA). Methods and results: In total, 891 participants with analysable serial CCTA and available glomerular filtration rate (GFR, derived using Cockcroft-Gault formulae) at baseline (CCTA 1) and follow-up (CCTA 2) were included. CKD was defined as GFR Abstract
Alcohol and alcoholism (Oxford, Oxfordshire), Volume 56, Issue 5, 1 1 2021, Pages 630-631 Response to Letter by Benson et al. on 'Hangover and the Effects of L-Cysteine'. Eriksson CJP, Metsälä M, Möykkynen T, Mäkisalo H, Kärkkäinen O, Palmén M, Salminen JE, Kauhanen J
Interactive cardiovascular and thoracic surgery, Volume 33, Issue 3, 1 1 2021, Pages 462-468 A modified surgical technique for aortopexy in tracheobronchomalacia. Dolmaci OB, Fockens MM, Oomen MW, van Woensel JB, Hoekstra CEL, Koolbergen DR
Objectives: Tracheobronchomalacia (TBM) is characterized by collapse of trachea, bronchi or both, leading to dyspnoea, expiratory stridor, coughing or recurrent airway infections. Surgical treatment with aortopexy is warranted for severe TBM. We describe a modified aortopexy technique with aortic wall strap sutures that evenly distributes the traction force over the full width of the aortic arch. The aim of this study was to determine the outcomes of this modified anterior aortopexy technique. M... Abstract
Cited 7 times since 2021 (2 per year) source: EuropePMC
The American journal of cardiology, Volume 156, 31 5 2021, Pages 9-15 Prevalence and Long-term Outcomes of Patients with Coronary Artery Ectasia Presenting with Acute Myocardial Infarction. Wang X, Montero-Cabezas JM, Mandurino-Mirizzi A, Hirasawa K, Ajmone Marsan N, Knuuti J, Bax JJ, Delgado V
Coronary artery ectasia (CAE) is described in 5% of patients undergoing coronary angiography. Previous studies have shown controversial results regarding the prognostic impact of CAE. The prevalence and prognostic value of CAE in patients with acute myocardial infarction (AMI) remain unknown. In 4788 patients presenting with AMI referred for coronary angiography the presence of CAE (defined as dilation of a coronary segment with a diameter ≥1.5 times of the adjacent normal segment) was confirmed... Abstract
Cited 1 times since 2021 (0.3 per year) source: EuropePMC
Heart rhythm, Volume 18, Issue 11, 30 5 2021, Pages 2023-2024 Reply to the Editor-Precordial R' wave: electrical disturbance-based or abnormal substrate-based? Hoogendoorn JC, Zeppenfeld K
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 28, Issue 6, 30 5 2021, Pages 2497-2499 Optimizing <sup>99m</sup>Tc-DPD scintigraphy: Adding value to the diagnosis and treatment of cardiac transthyretin amyloidosis. Stassen J, van der Bijl P, Bax JJ
Cited 2 times since 2021 (0.6 per year) source: EuropePMC
Nutrition (Burbank, Los Angeles County, Calif.), Volume 93, 29 5 2021, Pages 111440 Associations of metabolomic profiles with circulating vitamin E and urinary vitamin E metabolites in middle-aged individuals. Luo J, Hashimoto Y, Martens LG, Meulmeester FL, Ashrafi N, Mook-Kanamori DO, Rosendaal FR, Jukema JW, van Dijk KW, Mills K, le Cessie S, Noordam R, van Heemst D
Vitamin E (α-tocopherol [α-TOH]) is transported in lipoprotein particles in blood, but little is known about the transportation of its oxidized metabolites. In the Netherlands Epidemiology of Obesity Study, we aimed to investigate the associations of 147 circulating metabolomic measures obtained through targeted nuclear magnetic resonance with serum α-TOH and its urinary enzymatic (α-CEHC) and oxidized (α-TLHQ) metabolites from 24-h urine quantified by liquid chromatography with tandem mass spec... Abstract
Cited 5 times since 2021 (1.4 per year) source: EuropePMC
Vascular, Volume 30, Issue 5, 28 4 2021, Pages 867-873 Near-infrared fluorescence imaging with indocyanine green for quantification of changes in tissue perfusion following revascularization. Van den Hoven P, S Weller F, Van De Bent M, Goncalves LN, Ruig M, D Van Den Berg S, Ooms S, Mieog J, Ea Van De Bogt K, Van Schaik J, Schepers A, Vahrmeijer AL, Hamming JF, Van Der Vorst JR
Objectives: Current diagnostic modalities for patients with peripheral artery disease (PAD) mainly focus on the macrovascular level. For assessment of tissue perfusion, near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) seems promising. In this prospective cohort study, ICG NIR fluorescence imaging was performed pre- and post-revascularization to assess changes in foot perfusion. Methods: ICG NIR fluorescence imaging was performed in 36 patients with PAD pre- and post-interve... Abstract
Cited 4 times since 2021 (1.1 per year) source: EuropePMC
Angiology, Volume 73, Issue 2, 28 4 2021, Pages 112-119 Angiographic and Clinical Profile of Patients With COVID-19 Referred for Coronary Angiography During SARS-CoV-2 Outbreak: Results From a Collaborative, European, Multicenter Registry. Montero-Cabezas JM, Córdoba-Soriano JG, Díez-Delhoyo F, Abellán-Huerta J, Girgis H, Rama-Merchán JC, García-Blas S, van Rees JB, van Ramshorst J, Jurado-Román A
Data regarding angiographic characteristics, clinical profile, and inhospital outcomes of patients with coronavirus disease 2019 (COVID-19) referred for coronary angiography (CAG) are scarce. This is an observational study analyzing confirmed patients with COVID-19 referred for CAG from 10 European centers. We included 57 patients (mean age: 66 ± 15 years, 82% male) , of whom 18% had previous myocardial infarction (MI) and 29% had renal insufficiency and chronic pulmonary disease. ST-segment ele... Abstract
Cited 16 times since 2021 (4.5 per year) source: EuropePMC
Journal of the American Heart Association, Volume 10, Issue 15, 28 4 2021, Pages e014059 Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry. El-Battrawy I, Cammann VL, Kato K, Szawan KA, Di Vece D, Rossi A, Wischnewsky M, Hermes-Laufer J, Gili S, Citro R, Bossone E, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Heiner S, D'Ascenzo F, Dichtl W, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, David Arroja J, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Budnik M, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, Kozel M, Tousek P, Winchester DE, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm M, Maier LS, Pinto FJ, Widimský P, Felix SB, Opolski G, Braun-Dullaeus RC, Rottbauer W, Hasenfuß G, Pieske BM, Schunkert H, Thiele H, Bauersachs J, Katus HA, Horowitz JD, Di Ma
Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the International Takotsubo Registry, which is a multinational network with 26 participating center... Abstract
Cited 4 times since 2021 (1.1 per year) source: EuropePMC
European journal of heart failure, Volume 23, Issue 9, 28 4 2021, Pages 1428-1431 The ever-changing field of mechanical circulatory support: new challenges at the advent of the 'single device era'. Tops LF, Coats AJS, Ben Gal T
Cited 7 times since 2021 (1.9 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 38, Issue 1, 25 4 2021, Pages 183-193 Estimated pulse wave velocity (ePWV) as a potential gatekeeper for MRI-assessed PWV: a linear and deep neural network based approach in 2254 participants of the Netherlands Epidemiology of Obesity study. van Hout MJ, Dekkers IA, Lin L, Westenberg JJ, Schalij MJ, Jukema JW, Widya RL, Boone SC, de Mutsert R, Rosendaal FR, Scholte AJ, Lamb HJ
Pulse wave velocity (PWV) assessed by magnetic resonance imaging (MRI) is a prognostic marker for cardiovascular events. Prediction modelling could enable indirect PWV assessment based on clinical and anthropometric data. The aim was to calculate estimated-PWV (ePWV) based on clinical and anthropometric measures using linear ridge regression as well as a Deep Neural Network (DNN) and to determine the cut-off which provides optimal discriminative performance between lower and higher PWV values. I... Abstract