8892 results
Cited 8 times since 2023 (3.2 per year)
source: EuropePMC
Journal of Crohn's & colitis,
Volume 17, Issue 5, 1 1 2023, Pages 738-745
Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease.
Crouwel F, Simsek M, de Boer MA, Mulder CJJ, van Andel EM, Creemers RH, van Asseldonk DP, van Bodegraven AA, Horjus CS, Visschedijk MC, Weusthuis ALM, Seinen ML, Jharap B, van Schaik FDM, Ahmad I, Boekema PJ, Tack GJ, Wormmeester L, Lutgens MWMD, van Boeckel PGA, Gilissen LPL, Kerkhof M, Russel MGVM, Hoentjen F, Bartelink ME, Kuijvenhoven JP, Maljaars JWJ, van Dop WA, Wonders J, van der Voorn MMPJA, Buiter HJC, de Boer NK
Background: Safety of thioguanine in pregnant patients with inflammatory bowel disease [IBD] is sparsely recorded. This study was aimed to document the safety of thioguanine during pregnancy and birth. Methods: In this multicentre case series, IBD patients treated with thioguanine during pregnancy were included. Data regarding disease and medication history, pregnancy course, obstetric complications, and neonatal outcomes were collected. Results: Data on 117 thioguanine-exposed pregnancies in 99...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Revue scientifique et technique (International Office of Epizootics),
Volume 42, 1 1 2023, Pages 210-217
A framework for assessing confidence in freedom from infection in animal disease control programmes.
Van Schaik G, Madouasse A, van Roon AM, More SJ, Graham DA, Frossling J, Gethmann J, Fourichon C, Mercat M, Agren E, Sauter-Louis C, Gunn G, Eze J, Humphry R, Henry MK, Guelbenzu M, Nielen M, Santman-Berends IMG
In the Surveillance Tool for Outcome-based Comparison of FREEdom from infection (STOC free) project (https://www.stocfree.eu), a data collection tool was constructed to facilitate standardised collection of input data, and a model was developed to allow a standardised and harmonised comparison of the outputs of different control programmes (CPs) for cattle diseases. The STOC free model can be used to evaluate the probability of freedom from infection for herds in CPs and to determine whether the...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Interdisciplinary cardiovascular and thoracic surgery,
Volume 36, Issue 5, 1 1 2023, Pages ivad062
Leucocyte and platelet activation in cardiac surgery patients with and without lung injury: A prospective cohort study.
Van Paassen J, De Graaf-Dijkstra A, Brunsveld-Reinders AH, De Jonge E, Klautz RJM, Tsonaka R, Zwaginga JJ, Arbous MS
Objections: Development of acute lung injury after cardiac surgery is associated with an unfavourable outcome. Acute respiratory distress syndrome in general is, besides cytokine and interleukin activation, associated with activation of platelets, monocytes and neutrophils. In relation to pulmonary outcome after cardiac surgery, leucocyte and platelet activation is described in animal studies only. Therefore, we explored the perioperative time course of platelet and leucocyte activation in cardi...
Abstract
Cited 4 times since 2023 (1.6 per year)
source: EuropePMC
Photodiagnosis and photodynamic therapy,
Volume 42, 27 4 2023, Pages 103582
Ocular perfusion characteristics of children with newly diagnosed epilepsy.
Nalcacioglu P, Icoz M, Gultutan P, Yilmaz D, Citak Kurt AN
Background: To investigate the vascular changes of the optic nerve head (ONH) and macula by using optical coherence tomography angiography (OCT-A), and also the choroidal vascular structure by using an image binarization tool in children with newly diagnosed epilepsy and to then compare these parameters with healthy subjects. Methods: Forty-one epilepsy children and 36 healthy controls were included in this prospective and cross-sectional study.The radial peripapillary capillary (RPC) vessel den...
Abstract
Cited 9 times since 2023 (3.6 per year)
source: EuropePMC
Frontiers in pharmacology,
Volume 14, 27 4 2023, Pages 1098184
Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy.
Buijsers B, Garsen M, de Graaf M, Bakker-van Bebber M, Guo C, Li X, van der Vlag J
Introduction: The endothelial glycocalyx degrading enzyme heparanase-1 (HPSE1) is a major contributor to kidney diseases, such as glomerulonephritis and diabetic nephropathy. Therefore, inhibition of HPSE1 could be an interesting therapeutic strategy to treat glomerular diseases. A possible HPSE1 inhibitor is heparanase-2 (HPSE2) because HPSE2 is a structural homolog of HPSE1 without enzymatic activity. The importance of HPSE2 has been recently demonstrated in HPSE2-deficient mice, since these m...
Abstract
Internet interventions,
Volume 32, 27 4 2023, Pages 100626
Corrigendum to 'Put your money where your feet are: The real-world effects of StepBet gamified deposit contracts for physical activity' [Internet Interv., volume 31, March 2023, 100610].
de Buisonjé DR, Brosig F, Breeman LD, Bloom EL, Reijnders T, Janssen VR, Kraaijenhagen RA, Kemps HMC, Evers AWM
[This corrects the article DOI: 10.1016/j.invent.2023.100610.].
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 10, 26 4 2023, Pages 1094969
Microinvasive mitral valve surgery: Current status and status quo.
Tomšič A, Klautz RJM, Borger MA, Palmen M
Surgical mitral valve repair, performed either through median sternotomy or minimal invasive approach, presents the gold standard treatment for degenerative mitral valve disease. In dedicated centres, high repair and low complication rates have been established with excellent valve repair durability. Recently, new techniques have been introduced, that allow mitral valve repair to be performed through small surgical incisions and while avoiding cardio-pulmonary bypass. These new techniques, howev...
Abstract
Cited 4 times since 2023 (1.6 per year)
source: EuropePMC
The Canadian journal of cardiology,
Volume 39, Issue 10, 26 4 2023, Pages 1315-1324
Lipoprotein(a) and the Effect of Alirocumab on Revascularization After Acute Coronary Syndrome.
Steg PG, Szarek M, Valgimigli M, Islam S, Zeiher AM, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Goodman SG, Gotcheva N, Harrington RA, Jukema JW, Kim HS, Kim SH, Morais J, Pordy R, Scemama M, White HD, Schwartz GG, ODYSSEY OUTCOMES Investigators
Background: Many patients require revascularization after index acute coronary syndrome (ACS). Lipoprotein(a) is thought to play a pathogenic role in atherothrombosis. In ODYSSEY OUTCOMES, alirocumab reduced major adverse cardiovascular events after ACS, with greater reduction among those with higher lipoprotein(a) levels. We explored whether risk of revascularization after ACS was modified by the level of lipoprotein(a) and treatment with alirocumab or placebo. Methods: In ODYSSEY OUTCOMES alir...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Terapevticheskii arkhiv,
Volume 95, Issue 3, 26 4 2023, Pages 248-254
[Difficult case of differential diagnosis of partial lung atelectasis. Case report].
Gordeeva OM, Egorova AD, Chesalina YO, Gretcov EM, Semenova LA, Karpina NL, Sivokozov IV
In December 2018 the patient over 60 years old sought medical help with complaints of persistent cough. Based on computed tomography data there were identified the sings (symptoms) of right lung lower lobe atelectasis. To run this patient diagnostics there were performed 6 bronchoscopies narrowed down by bronchi checks up only and described the right lung central cancer picture. At the same time the biopsy taken during one of the bronchoscopies appeared non informative. Fine needle biopsy of med...
Abstract
Cited 11 times since 2023 (4.4 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 24, Issue 9, 25 4 2023, Pages 7818
Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation.
Inia JA, Stokman G, Pieterman EJ, Morrison MC, Menke AL, Verschuren L, Caspers MPM, Giera M, Jukema JW, van den Hoek AM, Princen HMG
Patients with metabolic syndrome are often prescribed statins to prevent the development of cardiovascular disease. Conversely, data on their effects on non-alcoholic steatohepatitis (NASH) are lacking. We evaluated these effects by feeding APOE*3-Leiden mice a Western-type diet (WTD) with or without atorvastatin to induce NASH and hepatic fibrosis. Besides the well-known plasma cholesterol lowering (-30%) and anti-atherogenic effects (severe lesion size -48%), atorvastatin significantly reduced...
Abstract
Cited 6 times since 2023 (2.4 per year)
source: EuropePMC
The Science of the total environment,
Volume 883, 25 4 2023, Pages 163599
Capturing the SARS-CoV-2 infection pyramid within the municipality of Rotterdam using longitudinal sewage surveillance.
de Graaf M, Langeveld J, Post J, Carrizosa C, Franz E, Izquierdo-Lara RW, Elsinga G, Heijnen L, Been F, van Beek J, Schilperoort R, Vriend R, Fanoy E, de Schepper EIT, Koopmans MPG, Medema G
Despite high vaccination rates in the Netherlands, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate. Longitudinal sewage surveillance was implemented along with the notification of cases as two parts of the surveillance pyramid to validate the use of sewage for surveillance, as an early warning tool, and to measure the effect of interventions. Sewage samples were collected from nine neighborhoods between September 2020 and November 2021. Comparative analysis an...
Abstract
Preventive veterinary medicine,
Volume 215, 25 4 2023, Pages 105927
SVEPM 2022, the annual conference of the Society for Veterinary Epidemiology and Preventive Medicine: A joyful hybrid meeting after two years online.
Dórea FC, Vergne T, Correia-Gomes C, Carmo LP, Fischer EAJ, Brodbelt DC, Robinson PA, van Schaik G
Abstract
Cited 31 times since 2023 (12.4 per year)
source: EuropePMC
Microbiome,
Volume 11, Issue 1, 21 3 2023, Pages 84
Gauge your phage: benchmarking of bacteriophage identification tools in metagenomic sequencing data.
Ho SFS, Wheeler NE, Millard AD, van Schaik W
Background: The prediction of bacteriophage sequences in metagenomic datasets has become a topic of considerable interest, leading to the development of many novel bioinformatic tools. A comparative analysis of ten state-of-the-art phage identification tools was performed to inform their usage in microbiome research. Methods: Artificial contigs generated from complete RefSeq genomes representing phages, plasmids, and chromosomes, and a previously sequenced mock community containing four phage sp...
Abstract
Cited 22 times since 2023 (8.8 per year)
source: EuropePMC
Frontiers in cellular and infection microbiology,
Volume 13, 21 3 2023, Pages 1160198
The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections.
Arunima A, van Schaik EJ, Samuel JE
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism. Depending on their cellular localization and interactions, they regulate chromatin function and assembly; and alter the stability and translation of cytoplasmic mRNAs. Although their proposed range of functionality remains controversial, there is increasing research ev...
Abstract
Cited 4 times since 2023 (1.6 per year)
source: EuropePMC
American heart journal,
Volume 262, 20 3 2023, Pages 55-65
Validation of the ARIC prediction model for sudden cardiac death in the European population: The ESCAPE-NET project.
Welten SJGC, Remmelzwaal S, Blom MT, van der Heijden AA, Nijpels G, Tan HL, van Valkengoed I, Empana JP, Jouven X, Ågesen FN, Warming PE, Tfelt-Hansen J, Prescott E, Jabbari R, Elders PJM, for ESCAPE-NET investigators,
Background: Sudden cardiac death is responsible for 10% to 20% of all deaths in Europe. The current study investigates how well the risk of sudden cardiac death can be predicted. To this end, we validated a previously developed prediction model for sudden cardiac death from the Atherosclerosis Risk in Communities study (USA). Methods: Data from participants of the Copenhagen City Heart Study (CCHS) (n=9988) was used to externally validate the previously developed prediction model for sudden card...
Abstract
Cited 6 times since 2023 (2.4 per year)
source: EuropePMC
Journal of tissue viability,
Volume 32, Issue 3, 20 3 2023, Pages 333-338
Analysis of the prevalence and risk factors of pressure injuries in the hospitalized pediatric population: A retrospective study.
Semerci R, Umaç EH, Yılmaz D, Karadağ A
Background: Pressure injury (PI) is an essential indicator of the quality of nursing care and affects hospitalized newborns and children. However, studies on the prevalence of PI and associated risk factors in children are limited. Aims: This study aimed to analyze the prevalence of PI and risk factors affecting the development of PI in the hospitalized pediatric population. Methods: This was a descriptive, retrospective study. Data were obtained via electronic medical records of 6350 pediatric...
Abstract
Cited 6 times since 2023 (2.4 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 10, Issue 4, 20 3 2023, Pages 180
Cardiac Fibrosis and Innervation State in Uncorrected and Corrected Transposition of the Great Arteries: A Postmortem Histological Analysis and Systematic Review.
Engele LJ, van der Palen RLF, Egorova AD, Bartelings MM, Wisse LJ, Glashan CA, Kiès P, Vliegen HW, Hazekamp MG, Mulder BJM, Ruiter MC, Bouma BJ, Jongbloed MRM
In the transposition of the great arteries (TGA), alterations in hemodynamics and oxygen saturation could result in fibrotic remodeling, but histological studies are scarce. We aimed to investigate fibrosis and innervation state in the full spectrum of TGA and correlate findings to clinical literature. Twenty-two human postmortem TGA hearts, including TGA without surgical correction (n = 8), after Mustard/Senning (n = 6), and arterial switch operation (ASO, n = 8), were studied. In newborn uncor...
Abstract
Frontiers in neuroscience,
Volume 17, 18 3 2023, Pages 1125210
Event-driven spectrotemporal feature extraction and classification using a silicon cochlea model.
Xu Y, Perera S, Bethi Y, Afshar S, van Schaik A
This paper presents a reconfigurable digital implementation of an event-based binaural cochlear system on a Field Programmable Gate Array (FPGA). It consists of a pair of the Cascade of Asymmetric Resonators with Fast Acting Compression (CAR-FAC) cochlea models and leaky integrate-and-fire (LIF) neurons. Additionally, we propose an event-driven SpectroTemporal Receptive Field (STRF) Feature Extraction using Adaptive Selection Thresholds (FEAST). It is tested on the TIDIGTIS benchmark and compare...
Abstract
The American journal of medicine,
Volume 136, Issue 7, 15 3 2023, Pages 720-721
Corrigendum to 'Integrating Coronary Atherosclerosis Burden and Progression with Coronary Artery Disease Risk Factors to Guide Therapeutic Decision Making' The American Journal of Medicine 136:03 (2023); 260-269.e7.
Freeman AM, Raman SV, Aggarwal M, Maron DJ, Bhatt DL, Parwani P, Osborne J, Earls JP, Min JK, Bax JJ, Shapiro MD
Abstract
Cited 10 times since 2023 (4 per year)
source: EuropePMC
Cancers,
Volume 15, Issue 8, 14 2 2023, Pages 2297
Radiomics of Tumor Heterogeneity in <sup>18</sup>F-FDG-PET-CT for Predicting Response to Immune Checkpoint Inhibition in Therapy-Naïve Patients with Advanced Non-Small-Cell Lung Cancer.
Ventura D, Schindler P, Masthoff M, Görlich D, Dittmann M, Heindel W, Schäfers M, Lenz G, Wardelmann E, Mohr M, Kies P, Bleckmann A, Roll W, Evers G
We aimed to evaluate the predictive and prognostic value of baseline 18F-FDG-PET-CT (PET-CT) radiomic features (RFs) for immune checkpoint-inhibitor (CKI)-based first-line therapy in advanced non-small-cell lung cancer (NSCLC) patients. In this retrospective study 44 patients were included. Patients were treated with either CKI-monotherapy or combined CKI-based immunotherapy-chemotherapy as first-line treatment. Treatment response was assessed by the Response Evaluation Criteria in Solid Tumors...
Abstract
