8892 results
Cited 14 times since 2023 (5.3 per year)
source: EuropePMC
European heart journal,
Volume 44, Issue 10, 1 1 2023, Pages 871-881
Factors influencing post-surgical survival in degenerative mitral regurgitation.
Butcher SC, Essayagh B, Steyerberg EW, Benfari G, Antoine C, Grigioni F, Le Tourneau T, Roussel JC, van Wijngaarden A, Marsan NA, Tribouilloy C, Rusinaru D, Hochstadt A, Topilsky Y, Michelena HI, Delgado V, Bax JJ, Enriquez-Sarano M
Aims: Indications for surgery in patients with degenerative mitral regurgitation (DMR) are increasingly liberal in all clinical guidelines but the role of secondary outcome determinants (left atrial volume index ≥60 mL/m2, atrial fibrillation, pulmonary artery systolic pressure ≥50 mmHg and moderate to severe tricuspid regurgitation) and their impact on post-operative outcome remain disputed. Whether these secondary outcome markers are just reflective of the DMR severity or intrinsically affect...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 24, Issue 4, 1 1 2023, Pages 424-425
The importance of big databases in understanding valvular heart disease.
Galloo X, Bax JJ
Abstract
Cited 16 times since 2023 (6.1 per year)
source: EuropePMC
Journal of medical virology,
Volume 95, Issue 3, 1 1 2023, Pages e28628
The diversity in the clinical features of children hospitalized with COVID-19 during the nonvariant, Alpha (B.1.1.7), Delta (B.1.617.2), and Omicron (B.1.1.529) variant periods of SARS CoV-2: Caution for neurological symptoms in Omicron variant.
Sahin A, Karadag-Oncel E, Buyuksen O, Ekemen-Keles Y, Ustundag G, Elvan-Tuz A, Tasar S, Didinmez-Taskirdi E, Baykan M, Kara-Aksay A, Yilmaz N, Olgac-Dundar N, Yilmaz D
Since the COVID-19 pandemic began, various severe acute respiratory syndrome coronavirus 2 variants have been identified with different characteristics than the nonvariant strain. We retrospectively evaluated the demographic and clinical differences in the cohort of hospitalized COVID-19 children (1 month-18 years old) between March 11, 2020, and September 31, 2022, by the time the variants identified in our country predominate. Bonferroni post hoc analysis was performed to compare the differenc...
Abstract
Cited 18 times since 2023 (6.8 per year)
source: EuropePMC
Journal of Crohn's & colitis,
Volume 17, Issue 2, 1 1 2023, Pages 221-230
Prophylactic Medication for the Prevention of Endoscopic Recurrence in Crohn's Disease: a Prospective Study Based on Clinical Risk Stratification.
Arkenbosch JHC, Beelen EMJ, Dijkstra G, Romberg-Camps M, Duijvestein M, Hoentjen F, van der Marel S, Maljaars PWJ, Jansen S, de Boer NKH, West RL, Horjus CS, Stassen LPS, van Schaik FDM, van Ruler O, Jharap BJH, Visschedijk M, Janssen A, Erler NS, Doukas M, Ooms AHAG, Kats-Ugurlu G, van der Woude CJ, de Vries AC
Background: To prevent recurrence after ileocolonic resection [ICR] in Crohn's disease [CD], postoperative prophylaxis based on risk stratification is recommended in international guidelines. This study aimed to evaluate postoperative CD recurrence after implementation of a clinical management algorithm and to determine the predictive value of clinical and histological risk factors [RFs]. Methods: In this multicentre, prospective cohort study, CD patients [≥16 years] scheduled for ICR were...
Abstract
Cited 15 times since 2023 (5.7 per year)
source: EuropePMC
Bioconjugate chemistry,
Volume 34, Issue 3, 1 1 2023, Pages 538-548
Generation of DAR1 Antibody-Drug Conjugates for Ultrapotent Payloads Using Tailored GlycoConnect Technology.
de Bever L, Popal S, van Schaik J, Rubahamya B, van Delft FL, Thurber GM, van Berkel SS
GlycoConnect technology can be readily adapted to provide different drug-to-antibody ratios (DARs) and is currently also evaluated in various clinical programs, including ADCT-601 (DAR2), MRG004a (DAR4), and XMT-1660 (DAR6). While antibody-drug conjugates (ADCs) typically feature a DAR2-8, it has become clear that ADCs with ultrapotent payloads (e.g., PBD dimers and calicheamicin) can only be administered to patients at low doses (
Abstract
Cited 5 times since 2023 (1.9 per year)
source: EuropePMC
Ocular immunology and inflammation,
Volume 32, Issue 7, 28 4 2023, Pages 1150-1154
Non-Infectious Uveitis Secondary to Dupilumab Treatment in Atopic Dermatitis Patients Shows a Pro-Inflammatory Molecular Profile.
Achten R, van Luijk C, Thijs J, Drylewicz J, Delemarre E, Nierkens S, Bakker D, van Wijk F, de Graaf M, de Bruin-Weller M, de Boer J, Kuiper J
Severe uveitis is a rare complication of interleukin-4 receptor alpha blocking by dupilumab in topic dermatitis (AD) patients. The aim of this study was to describe five moderate-to-severe AD patients who developed uveitis during dupilumab treatment and to compare the proteomic profile of aqueous humor (AqH) of dupilumab-associated uveitis (n=3/5 available samples) with non-infectious uveitis (n=27) and cataract controls (n=11). Included patients were treated at the University Medical Center Utr...
Abstract
Cited 6 times since 2023 (2.3 per year)
source: EuropePMC
PLoS biology,
Volume 21, Issue 2, 28 4 2023, Pages e3002016
Extended parental provisioning and variation in vertebrate brain sizes.
van Schaik CP, Song Z, Schuppli C, Drobniak SM, Heldstab SA, Griesser M
Large brains provide adaptive cognitive benefits but require unusually high, near-constant energy inputs and become fully functional well after their growth is completed. Consequently, young of most larger-brained endotherms should not be able to independently support the growth and development of their own brains. This paradox is solved if the evolution of extended parental provisioning facilitated brain size evolution. Comparative studies indeed show that extended parental provisioning coevolv...
Abstract
Cited 5 times since 2023 (1.9 per year)
source: EuropePMC
Research and practice in thrombosis and haemostasis,
Volume 7, Issue 2, 27 4 2023, Pages 100096
Atrial fibrillation in cancer: thromboembolism and bleeding in daily practice.
Chu G, Seelig J, Cannegieter SC, Gelderblom H, Hovens MMC, Huisman MV, van der Hulle T, Trines SA, Vlot AJ, Versteeg HH, Hemels MEW, Klok FA
Background: Cancer is suggested to confer thromboembolic and bleeding risk in patients with atrial fibrillation (AF). Objectives: We aimed to describe current anticoagulant practice in patients with AF and active cancer, present incidences of thromboembolic and bleeding complications, and evaluate the association between cancer type or anticoagulant management strategy with AF-related complications. Methods: This retrospective study identified patients with AF and active cancer in 2 hospitals be...
Abstract
Cited 2 times since 2023 (0.8 per year)
source: EuropePMC
Internet interventions,
Volume 31, 26 4 2023, Pages 100610
Put your money where your feet are: The real-world effects of StepBet gamified deposit contracts for physical activity.
de Buisonjé DR, Brosig F, Breeman LD, Bloom EL, Reijnders T, Janssen VR, Kraaijenhagen RA, Kemps HMC, Evers AWM
Background: Gamification and deposit contracts (a financial incentive in which participants pledge their own money) can enhance effectiveness of mobile behavior change interventions. However, to assess their potential for improving population health, research should investigate implementation of gamified deposit contracts outside the research setting. Therefore, we analyzed data from StepBet, a smartphone application originally developed by WayBetter, Inc. Objective: To perform a naturalistic ev...
Abstract
Cited 6 times since 2023 (2.3 per year)
source: EuropePMC
Genes,
Volume 14, Issue 3, 25 4 2023, Pages 578
Feasibility of Community Pharmacist-Initiated and Point-of-Care <i>CYP2C19</i> Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors.
Levens AD, den Haan MC, Jukema JW, Heringa M, van den Hout WB, Moes DJAR, Swen JJ
Tailoring antiplatelet therapy based on CYP2C19 pharmacogenetic (PGx) testing can improve cardiovascular outcomes and potentially reduce healthcare costs in patients on a P2Y12-inhibitor regime with prasugrel or ticagrelor. However, ubiquitous adoption-particularly in an outpatient setting-remains limited. We conducted a proof-of-concept study to evaluate the feasibility of CYP2C19-guided de-escalation of prasugrel/ticagrelor to clopidogrel through point-of-care (POC) PGx testing in the communit...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
The International journal of angiology : official publication of the International College of Angiology, Inc,
Volume 33, Issue 3, 25 4 2023, Pages 148-155
Validity of Routinely Reported Rutherford Scores Reported by Clinicians as Part of Daily Clinical Practice.
van der Heijden LLM, Marang-van de Mheen PJ, Thielman L, Stijnen P, Hamming JF, Fourneau I
Routinely reported structured data from the electronic health record (EHR) are frequently used for secondary purposes. However, it is unknown how valid routinely reported data are for reuse. This study aimed to assess the validity of routinely reported Rutherford scores by clinicians as an indicator for the validity of structured data in the EHR. This observational study compared clinician-reported Rutherford scores with medical record review Rutherford scores for all visits at the vascular surg...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
European urology,
Volume 83, Issue 5, 24 4 2023, Pages e140-e141
Erratum to "European Association of Urology (EAU) Prognostic Factor Risk Groups for Non-muscle-invasive Bladder Cancer (NMIBC) Incorporating the WHO 2004/2016 and WHO 1973 Classification Systems for Grade: An Update from the EAU NMIBC Guidelines Panel" [Eur. Urol. 79(4) (2021) 480-488].
Sylvester RJ, Rodríguez O, Hernández V, Turturica D, Bauerová L, Max Bruins H, Bründl J, van der Kwast TH, Brisuda A, Rubio-Briones J, Seles M, Hentschel AE, Kusuma VRM, Huebner N, Cotte J, Mertens LS, Volanis D, Cussenot O, Subiela Henríquez JD, de la Peña E, Pisano F, Pešl M, van der Heijden AG, Herdegen S, Zlotta AR, Hacek J, Calatrava A, Mannweiler S, Bosschieter J, Ashabere D, Haitel A, Côté JF, El Sheikh S, Lunelli L, Algaba F, Alemany I, Soria F, Runneboom W, Breyer J, Nieuwenhuijzen JA, Llorente C, Molinaro L, Hulsbergen-van de Kaa CA, Evert M, Kiemeney LALM, N'Dow J, Plass K, Čapoun O, Soukup V, Dominguez-Escrig JL, Cohen D, Palou J, Gontero P, Burger M, Zigeuner R, Mostafid AH, Shariat SF, Rouprêt M, Compérat EM, Babjuk M, van Rhijn BWG
Abstract
Cited 8 times since 2023 (3 per year)
source: EuropePMC
JTO clinical and research reports,
Volume 4, Issue 4, 24 4 2023, Pages 100475
Long-Term Outcomes After Chemoradiotherapy and Surgery for Superior Sulcus Tumors.
Ünal S, Winkelman JA, Heineman DJ, Bahce I, van Dorp M, Braun JA, Hashemi S, Senan S, Paul MA, Dahele M, Dickhoff C
Introduction: Superior sulcus tumors (SSTs) are uncommon, and their anatomical location can make treatment challenging. We analyzed late outcomes of patients with SST treated with concurrent chemoradiotherapy followed by surgical resection (trimodality) in a single tertiary institution. Methods: Patients with non-small cell SSTs, who underwent trimodality therapy between 2002 and 2017, were selected from a prospective institutional surgical database. Patients were uniformly staged with 18F-fluor...
Abstract
Cited 9 times since 2023 (3.4 per year)
source: EuropePMC
Avian pathology : journal of the W.V.P.A,
Volume 52, Issue 3, 24 4 2023, Pages 157-167
Genetic analysis of infectious bronchitis virus (IBV) in vaccinated poultry populations over a period of 10 years.
Vermeulen CJ, Dijkman R, de Wit JJS, Bosch BJ, Heesterbeek JAPH, van Schaik G
Infectious bronchitis virus (IBV) is an avian pathogen from the Coronavirus family causing major health issues in poultry flocks worldwide. Because of its negative impact on health, performance, and bird welfare, commercial poultry are routinely vaccinated by administering live attenuated virus. However, field strains are capable of rapid adaptation and may evade vaccine-induced immunity. We set out to describe dynamics within and between lineages and assess potential escape from vaccine-induced...
Abstract
Cited 41 times since 2023 (15.5 per year)
source: EuropePMC
Journal of affective disorders,
Volume 329, 23 4 2023, Pages 19-29
Antidepressants or running therapy: Comparing effects on mental and physical health in patients with depression and anxiety disorders.
Verhoeven JE, Han LKM, Lever-van Milligen BA, Hu MX, Révész D, Hoogendoorn AW, Batelaan NM, van Schaik DJF, van Balkom AJLM, van Oppen P, Penninx BWJH
Background: Antidepressant medication and running therapy are both effective treatments for patients with depressive and anxiety disorders. However, they may work through different pathophysiological mechanisms and could differ in their impact on physical health. This study examined effects of antidepressants versus running therapy on both mental and physical health. Methods: According to a partially randomized patient preference design, 141 patients with depression and/or anxiety disorder were...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Open research Europe,
Volume 3, 23 4 2023, Pages 40
Integrated secure distance bounding and hardware-based security: A case study for the insurance claim verification of farmers during COVID-19.
Kanak A, Ergün S, Arif İ, Tanrıseven S, Uğur N, van Schaik GJ, Badii A
Given the rapidly evolving developments in Fintech, Insurtech, Open Banking, and Mobile Money business models in recent years, the capability for ensuring strong authentication remains the most pressing need for the protection of security and privacy of data in this sector as in many other areas. The security-integrity of insurance and financial transactions and workflows is vitally dependent on access control mechanisms to deliver strong multi-factor authentication (MFA) with operationally acce...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD,
Volume 33, Issue 5, 23 4 2023, Pages 1077-1086
The association between leptin and subclinical cardiovascular disease explained by body fat: Observational and Mendelian randomization analyses.
Christen T, de Mutsert R, Smit RA, Willems van Dijk K, Lamb HJ, Rosendaal FR, Jukema JW, Trompet S
Background and aims: Leptin has been associated with adverse effects on cardiovascular disease, but the effect of confounding by body fat in these associations remains unclear. To investigate associations between leptin and heart function and subclinical cardiovascular disease adjusted for total body fat, and to investigate the causal relation between leptin and cardiovascular disease using Mendelian randomisation. Methods and results: Leptin concentrations, total body fat and diverse measures o...
Abstract
Cited 1 times since 2023 (0.4 per year)
source: EuropePMC
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners,
Volume 29, Issue 8, 23 4 2023, Pages 1915-1920
Evaluation of biliary toxicity in patients with hepatic artery infusion pumps.
Elijah J, Schepers AJ, Krauss JC, McDevitt RL
Purpose: Identify risk factors for biliary toxicity in patients with colorectal liver metastases who received floxuridine (FUDR) via a surgically implanted hepatic artery infusion pump (HAIP). Describe the incidence of biliary toxicity and evaluate relevant patterns in the biliary toxicity cohort. Methods: A single center, retrospective, case-control study included adult colorectal cancer patients with liver metastases who received at least one cycle of FUDR via a surgically implanted HAIP from...
Abstract
Cited 8 times since 2023 (3 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 109, Issue 6, 23 4 2023, Pages 478-484
Prognostic impact of left ventricular global longitudinal strain in atrial mitral regurgitation.
Meucci MC, Stassen J, Tomsic A, Palmen M, Crea F, Bax JJ, Ajmone Marsan N, Delgado V
Objective: Left atrial (LA) and left ventricular (LV) mechanics are impaired in patients with atrial functional mitral regurgitation (AFMR), but their prognostic value in this subset of patients remains unknown. The present study aimed to evaluate the association between LA and LV longitudinal strain and clinical outcomes in patients with AFMR. Methods: A total of 197 patients (mean age 73±10 years, 44% men) with at least moderate AFMR were retrospectively identified. LV global longitudinal stra...
Abstract
Cited 2 times since 2023 (0.8 per year)
source: EuropePMC
Magma (New York, N.Y.),
Volume 36, Issue 5, 23 4 2023, Pages 701-709
A comparison of myocardial magnetic resonance extracellular volume mapping at 3 T against histology of tissue collagen in severe aortic valve stenosis and obstructive hypertrophic cardiomyopathy.
Bakermans AJ, Kouwenhoven M, de Vos J, de Vries DK, Reckman YJ, Farag ES, Koolbergen DR, Kluin J, Nederveen AJ, Strijkers GJ, Boekholdt SM
Objective: Quantitative extracellular volume fraction (ECV) mapping with MRI is commonly used to investigate in vivo diffuse myocardial fibrosis. This study aimed to validate ECV measurements against ex vivo histology of myocardial tissue samples from patients with aortic valve stenosis or hypertrophic cardiomyopathy. Materials and methods: Sixteen patients underwent MRI examination at 3 T to acquire native T1 maps and post-contrast T1 maps after gadobutrol administration, from which hematocrit-...
Abstract
