7154 results
Cited 19 times since 2014 (1.7 per year)
source: EuropePMC
Heart rhythm,
Volume 11, Issue 5, 22 4 2014, Pages 806-813
QRS fusion complex analysis using wave interference to predict reverse remodeling during cardiac resynchronization therapy.
Sweeney MO, Hellkamp AS, van Bommel RJ, Schalij MJ, Borleffs CJ, Bax JJ
Background: Biventricular (BV) electrical wavefront fusion can induce improvement in left ventricular (LV) size and function during cardiac resynchronization therapy (CRT). Changes in BV wave propagation sequence and duration register in the QRS complex on the standard electrocardiogram. We developed a wave interference method for the characterization of BV fusion to predict LV reverse remodeling. Objective: To develop a simple electrocardiographic method for predicting reverse remodeling during...
Abstract
Cited 77 times since 2014 (6.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 100, Issue 12, 21 3 2014, Pages 960-968
Significant lead-induced tricuspid regurgitation is associated with poor prognosis at long-term follow-up.
Höke U, Auger D, Thijssen J, Wolterbeek R, van der Velde ET, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Although the presence of an RV lead is a potential cause of tricuspid regurgitation (TR), the clinical impact of significant lead-induced TR is unknown. Objective: To evaluate the effect of significant lead-induced TR on cardiac performance and long-term outcome after cardioverter-defibrillator (ICD) or pacemaker implantation. Methods: A retrospective cohort of 239 ICD (n=191) or pacemaker (n=48) recipients (age 60±14 years, 77% male) from a tertiary care university hospital, with an...
Abstract
Cited 25 times since 2014 (2.2 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 148, Issue 4, 15 3 2014, Pages 1490-1497
Exercise capacity in children after total cavopulmonary connection: lateral tunnel versus extracardiac conduit technique.
Bossers SS, Helbing WA, Duppen N, Kuipers IM, Schokking M, Hazekamp MG, Bogers AJ, Ten Harkel AD, Takken T
Objectives: In patients with univentricular heart disease, the total cavopulmonary connection (TCPC) is the preferred treatment. TCPC can be performed using the intra-atrial lateral tunnel (ILT) or extracardiac conduit (ECC) technique. The purpose of the present study was to evaluate exercise capacity in contemporary TCPC patients and compare the results between the 2 techniques. Methods: A total of 101 TCPC patients (ILT, n=42; ECC, n=59; age, 12.2±2.6 years; age at TCPC completion, 3.2±1.1 yea...
Abstract
Cited 62 times since 2014 (5.6 per year)
source: EuropePMC
International journal of epidemiology,
Volume 43, Issue 3, 14 2 2014, Pages 878-886
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.
Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE
Background: Human leukocyte telomere length (LTL) decreases with age and shorter LTL has previously been associated with increased prospective mortality. However, it is not clear whether LTL merely marks the health status of an individual by its association with parameters of immune function, for example, or whether telomere shortening also contributes causally to lifespan variation in humans. Methods: We measured LTL in 870 nonagenarian siblings (mean age 93 years), 1580 of their offspring and...
Abstract
Cited 12 times since 2014 (1.1 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 27, Issue 3, 13 2 2014, Pages 239-248
Association between multilayer left ventricular rotational mechanics and the development of left ventricular remodeling after acute myocardial infarction.
Abate E, Hoogslag GE, Leong DP, Bertini M, Antoni ML, Nucifora G, Joyce E, Holman ER, Siebelink HM, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Background: The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) to evaluate the association between peak subepicardial and subendocardial twist and LV remodeling 6 months af...
Abstract
Cited 5 times since 2014 (0.4 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 59, Issue 5, 11 2 2014, Pages 1315-22.e1
National variation in the utilization of alternative imaging in peripheral arterial disease.
de Vos MS, Hawkins AT, Hevelone ND, Hamming JF, Nguyen LL
Objective: The value and cost-effectiveness of less invasive alternative imaging (AI) modalities (duplex ultrasound scanning, computed tomography angiography, and magnetic resonance angiography) in the care of peripheral arterial disease (PAD) has been reported; however, there is no consensus on their role. We hypothesized that AI utilization is low compared with angiography in the United States and that patient and hospital characteristics are both associated with AI utilization. Methods: The N...
Abstract
Cited 13 times since 2014 (1.2 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 34, Issue 3, 9 2 2014, Pages 594-602
Absence of chemokine (C-x-C motif) ligand 10 diminishes perfusion recovery after local arterial occlusion in mice.
van den Borne P, Haverslag RT, Brandt MM, Cheng C, Duckers HJ, Quax PH, Hoefer IE, Pasterkamp G, de Kleijn DP
Objective: In arteriogenesis, pre-existing anastomoses undergo enlargement to restore blood flow in ischemic tissues. Chemokine (C-X-C motif) ligand 10 (CXCL10) is secreted after Toll-like receptor activation. Toll-like receptors are involved in arteriogenesis; however, the role of CXCL10 is still unclear. In this study, we investigated the role for CXCL10 in a murine hindlimb ischemia model. Approach and results: Unilateral femoral artery ligation was performed in wild-type (WT) and CXCL10(-/-)...
Abstract
Revista espanola de cardiologia (English ed.),
Volume 67, Issue 2, 8 2 2014, Pages 157
Appropriate use criteria for cardiopulmonary exercise testing in patients with cardiac resynchronization devices. Response.
de Riva-Silva M, López-Gil M, Fontenla-Cerezuela A, Arribas-Ynsaurriaga F
Abstract
Cited 22 times since 2014 (2 per year)
source: EuropePMC
Human gene therapy,
Volume 25, Issue 1, 7 1 2014, Pages 41-49
Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia.
Lijkwan MA, Hellingman AA, Bos EJ, van der Bogt KE, Huang M, Kooreman NG, de Vries MR, Peters HA, Robbins RC, Hamming JF, Quax PH, Wu JC
In this study, we target the hypoxia inducible factor-1 alpha (HIF-1-alpha) pathway by short hairpin RNA interference therapy targeting prolyl hydroxylase-2 (shPHD2). We use the minicircle (MC) vector technology as an alternative for conventional nonviral plasmid (PL) vectors in order to improve neovascularization after unilateral hindlimb ischemia in a murine model. Gene expression and transfection efficiency of MC and PL, both in vitro and in vivo, were assessed using bioluminescence imaging (...
Abstract
Cited 3 times since 2014 (0.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 172, Issue 1, 4 1 2014, Pages e3-5
Confounding factors in the relation between high sensitivity cardiac troponin T levels in serum and infarct size of patients with first ST-elevation myocardial infarction.
Cobbaert CM, Bootsma M, Boden H, Ahmed TA, Hoogslag GE, Romijn FP, Ballieux BE, Wolterbeek R, Hermens WT, Schalij MJ, van der Laarse A
Abstract
Cited 36 times since 2014 (3.2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 1, 1 1 2014, Pages 3-10
Heart disease in the Netherlands: a quantitative update.
Leening MJ, Siregar S, Vaartjes I, Bots ML, Versteegh MI, van Geuns RJ, Koolen JJ, Deckers JW
In this review we discuss cardiovascular mortality, incidence and prevalence of heart disease, and cardiac interventions and surgery in the Netherlands. We combined most recently available data from various Dutch cardiovascular registries, Dutch Hospital Data (LMR), Statistics Netherlands (CBS), and population-based cohort studies, to provide a broad quantitative update. The absolute number of people dying from cardiovascular diseases is declining and cardiovascular conditions are no longer the...
Abstract
Cited 9 times since 2014 (0.8 per year)
source: EuropePMC
Diabetes care,
Volume 37, Issue 1, 1 1 2014, Pages e1-2
Very-low-calorie diet increases myocardial triglyceride content and decreases diastolic left ventricular function in type 2 diabetes with cardiac complications.
Jonker JT, Djaberi R, van Schinkel LD, Hammer S, Bus MT, Kerpershoek G, Kharagjitsingh AV, Romijn JA, Bax JJ, Jukema JW, de Roos A, Smit JW, Lamb HJ
Abstract
Cited 2 times since 2014 (0.2 per year)
source: EuropePMC
Journal of cardiovascular pharmacology,
Volume 63, Issue 1, 1 1 2014, Pages 16-22
Toll-like receptor 4 inhibitor TAK-242 treatment does not influence perfusion recovery in tissue ischemia.
van den Borne P, Bastiaansen AJ, de Vries MR, Quax PH, Hoefer IE, Pasterkamp G
Toll-like receptors (TLRs) are important in innate immune responses, which are crucial in collateral artery formation (arteriogenesis). TLR4⁻/⁻ mice undergoing hind limb ischemia show decreased perfusion recovery accompanied by an impaired infiltration of inflammatory cells. TLR antagonists are currently developed and tested with the objective to inhibit acute exacerbation of organ damaging immune responses. However, systemic inhibition of innate immune responses may negatively influence arterio...
Abstract
Cited 181 times since 2014 (16.2 per year)
source: EuropePMC
JAMA,
Volume 311, Issue 3, 1 1 2014, Pages 252-262
Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial.
Nicholls SJ, Kastelein JJ, Schwartz GG, Bash D, Rosenson RS, Cavender MA, Brennan DM, Koenig W, Jukema JW, Nambi V, Wright RS, Menon V, Lincoff AM, Nissen SE, VISTA-16 Investigators
Importance: Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor varespladib has favorable effects on lipid and inflammatory markers; however, its effect on cardiovascular outcomes is unknown. Objective: To determine the effects of sPLA2 inhibition with varespladib on cardiovascular outcomes. Design, setting, and participants: A double-blind, randomized, multicenter trial at 362 academic and community hospitals in Europe,...
Abstract
Cited 34 times since 2014 (3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 1, 1 1 2014, Pages 11-19
A review of the positive and negative effects of cardiovascular drugs on sexual function: a proposed table for use in clinical practice.
Nicolai MP, Liem SS, Both S, Pelger RC, Putter H, Schalij MJ, Elzevier HW
Several antihypertensive drugs, such as diuretics and β-blockers, can negatively affect sexual function, leading to diminished quality of life and often to noncompliance with the therapy. Other drug classes, however, such as angiotensin II receptor blockers (ARBs) are able to improve patients' sexual function. Sufficient knowledge about the effects of these widely used antihypertensive drugs will make it possible for cardiologists and general practitioners to spare and even improve patients...
Abstract
Turk patoloji dergisi,
Volume 30, Issue 2, 1 1 2014, Pages 118-123
A study on distribution of cancer cases diagnosed in Çorum.
Baş Y, Uzbay P, Güney G, Erenler BH, Yilmaz D, Ozdemır C
Objective: In order to help obtain accurate knowledge and to contribute to the establishment of data for regional tumor statistics, we aimed to determine the frequency distribution of cancer cases that was diagnosed in Çorum province. Material and method: In this descriptive study, we retrospectively reviewed the archive records of the pathology departments' of one university hospital and two private hospitals serving in the province of Çorum. A total of 138,973 recorded pathology reports w...
Abstract
Cited 23 times since 2014 (2.1 per year)
source: EuropePMC
Acta cirurgica brasileira,
Volume 29, Issue 1, 1 1 2014, Pages 59-65
Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs.
Yilmaz D, Dogan N, Ozkan A, Sencimen M, Ora BE, Mutlu I
Purpose: To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. Methods: Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals were sacrificed on the 12th postoperative week and the tibial bones were removed, histologic sections we...
Abstract
Bratislavske lekarske listy,
Volume 115, Issue 7, 1 1 2014, Pages 400-404
Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitis.
Comu FM, Ozturk L, Alkan M, Pampal K, Arslan M, Isik B, Atac MS, Yilmaz D
Purpose: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats. Materials and methods: Twenty- eight Wistar Albino rats were included in the study after streptozocin (60 mg/kg) treatment for 4 weeks of observation for diabetes presence. Twenty-eight rats were allocated to 4 groups. In group DP (n = 7) 150 mg.kg-1 of propofol was injected intraperitoneally. In group DP-vit C (n = 7) rats 100 mg/kg of vitamin C (Ascorbic aci...
Abstract
Cited 23 times since 2013 (2.1 per year)
source: EuropePMC
European heart journal,
Volume 35, Issue 10, 29 5 2014, Pages 633-638
Risks and benefits of cardiac imaging: an analysis of risks related to imaging for coronary artery disease.
Knuuti J, Bengel F, Bax JJ, Kaufmann PA, Le Guludec D, Perrone Filardi P, Marcassa C, Ajmone Marsan N, Achenbach S, Kitsiou A, Flotats A, Eeckhout E, Minn H, Hesse B
Abstract
Cited 105 times since 2013 (9.4 per year)
source: EuropePMC
Journal of virology,
Volume 88, Issue 5, 26 4 2013, Pages 2844-2857
Genomewide analysis of reassortment and evolution of human influenza A(H3N2) viruses circulating between 1968 and 2011.
Westgeest KB, Russell CA, Lin X, Spronken MI, Bestebroer TM, Bahl J, van Beek R, Skepner E, Halpin RA, de Jong JC, Rimmelzwaan GF, Osterhaus AD, Smith DJ, Wentworth DE, Fouchier RA, de Graaf M
Unlabelled: Influenza A(H3N2) viruses became widespread in humans during the 1968 H3N2 virus pandemic and have been a major cause of influenza epidemics ever since. These viruses evolve continuously by reassortment and genomic evolution. Antigenic drift is the cause for the need to update influenza vaccines frequently. Using two data sets that span the entire period of circulation of human influenza A(H3N2) viruses, it was shown that influenza A(H3N2) virus evolution can be mapped to 13 antigeni...
Abstract
