Research

Publications

Below you can find a list of our published research.

6128 results

Cited 21 times since 2009 (1.3 per year) source: EuropePMC

Acta anaesthesiologica Scandinavica, Volume 53, Issue 7, 6 1 2009, Pages 941-948 Anti-ischemic effects of inotropic agents in experimental right ventricular infarction. Hein M, Roehl AB, Baumert JH, Scherer K, Steendijk P, Rossaint R

Background: Right ventricular (RV) function is an important determinant of survival after myocardial infarction. The efficacy of reperfusion therapy might be increased by the cardioprotective action of inotropic agents, which are used for symptomatic therapy in situations with compromised hemodynamics. Therefore, we used a porcine model of RV ischemia and reperfusion (IR) injury to study the influence of milrinone, levosimendan and dobutamine on the extent and degree of myocardial injury. Method... Abstract

Cited 40 times since 2009 (2.5 per year) source: EuropePMC

Current medical research and opinion, Volume 25, Issue 5, 1 1 2009, Pages 1171-1178 Physicians' attitudes and adherence to use of risk scores for primary prevention of cardiovascular disease: cross-sectional survey in three world regions. Sposito AC, Ramires JA, Jukema JW, Molina JC, da Silva PM, Ghadanfar MM, Wilson PW

Objective: To evaluate physicians' attitudes and adherence to the use of risk scores in the primary prevention of cardiovascular disease (CVD). Design and methods: A cross-sectional survey of 2056 physicians involved in the primary prevention of CVD. Participants included cardiologists (47%), general practitioners (42%), and endocrinologists (11%) from several geographical regions: Brazil (n = 968), USA (n = 381), Greece (n = 275), Chile (n = 157), Venezuela (n = 128), Portugal (n = 42), Th... Abstract

Cited 2 times since 2009 (0.1 per year) source: EuropePMC

Cardiology clinics, Volume 27, Issue 2, 1 1 2009, Pages 265-76, Table of Contents Nuclear imaging in heart failure. Bax JJ, Boogers MM, Schuijf JD

Heart failure is becoming the main clinical challenge in cardiology in the twenty-first century and is associated with high morbidity and mortality. Currently, several therapeutic options are available for heart failure patients, including medical therapy, revascularization, advanced cardiac surgery, device therapy, and cardiac transplantation. Future therapies are directed at cell and gene therapy. In this article the role of nuclear imaging in the management of heart failure patients is discus... Abstract

Cited 2 times since 2009 (0.1 per year) source: EuropePMC

Chronobiology international, Volume 26, Issue 4, 1 1 2009, Pages 637-652 Myocardial infarction occurs with a similar 24 h pattern in the 4G/5G versions of plasminogen activator inhibitor-1. Bergheanu SC, Pons D, Jukema JW, van der Hoeven BL, Liem SS, Vandenbroucke JP, Rosendaal FR, le Cessie S, Schalij MJ, van der Bom JG

PAI-1 expression is regulated by a 4G/5G promoter polymorphism. The 4G allele is associated with greater circadian variation of PAI-1 levels. We hypothesized that the 24 h variation of cardiac risk is more pronounced among persons with the 4G4G genotype than among ones with 4G5G and 5G5G genotypes. We assessed the time of onset of symptoms in 623 consecutive patients with acute myocardial infarction (AMI) enrolled in the MISSION! Study between February 1, 2004, and October 29, 2006. All of the p... Abstract

Cited 177 times since 2009 (11.2 per year) source: EuropePMC

JAMA, Volume 301, Issue 19, 1 1 2009, Pages 1997-2004 Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial. van Ramshorst J, Bax JJ, Beeres SL, Dibbets-Schneider P, Roes SD, Stokkel MP, de Roos A, Fibbe WE, Zwaginga JJ, Boersma E, Schalij MJ, Atsma DE

Context: Previous studies have suggested that bone marrow cell injection may improve myocardial perfusion and left ventricular (LV) function in patients with chronic myocardial ischemia. Objective: To investigate the effect of intramyocardial bone marrow cell injection on myocardial perfusion and LV function in patients with chronic myocardial ischemia. Design, setting, and patients: Randomized, double-blind, placebo-controlled trial at a Netherlands university hospital, May 1, 2005-March 3, 200... Abstract

Cited 107 times since 2009 (6.8 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 53, Issue 21, 1 1 2009, Pages 1933-1943 Echocardiography and noninvasive imaging in cardiac resynchronization therapy: results of the PROSPECT (Predictors of Response to Cardiac Resynchronization Therapy) study in perspective. Bax JJ, Gorcsan J

Abstract

Cited 31 times since 2009 (2 per year) source: EuropePMC

Coronary artery disease, Volume 20, Issue 3, 1 1 2009, Pages 219-224 Incremental value of high-sensitivity C-reactive protein and N-terminal pro-B-type natriuretic peptide for the prediction of postoperative cardiac events in noncardiac vascular surgery patients. Goei D, Hoeks SE, Boersma E, Winkel TA, Dunkelgrun M, Flu WJ, Schouten O, Bax JJ, Poldermans D

Objectives: High-sensitivity C-reactive protein (hs-CRP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are associated with the presence of coronary artery disease. The aim of this study was to assess the prognostic value of hs-CRP and NT-proBNP for postoperative cardiac events in noncardiac vascular surgery patients. Methods: In 592 patients, cardiac history, hs-CRP, and NT-proBNP levels were assessed preoperatively. Levels of hs-CRP of at least 6.5 mg/l and NT-proBNP of at least 350... Abstract

Cited 14 times since 2009 (0.9 per year) source: EuropePMC

American heart journal, Volume 157, Issue 5, 1 1 2009, Pages 919-925 Preoperative oral glucose tolerance testing in vascular surgery patients: long-term cardiovascular outcome. van Kuijk JP, Dunkelgrun M, Schreiner F, Flu WJ, Galal W, van Domburg RT, Hoeks SE, van Gestel YR, Bax JJ, Poldermans D

Background: Diabetes mellitus (DM) is an important risk factor in vascular surgery patients, influencing late outcome. Screening for diabetes is recommended by fasting glucose measurement. Oral glucose tolerance testing (OGTT) could enhance the detection of patients with impaired glucose tolerance (IGT) and DM. Aim: To assess the additional value of OGTT on top of fasting glucose levels in vascular surgery patients to predict long-term cardiovascular outcome. Methods: A total of 404 patients wit... Abstract

Cited 80 times since 2009 (5 per year) source: EuropePMC

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 50, Issue 5, 1 1 2009, Pages 718-725 Quantitative gated SPECT-derived phase analysis on gated myocardial perfusion SPECT detects left ventricular dyssynchrony and predicts response to cardiac resynchronization therapy. Boogers MM, Van Kriekinge SD, Henneman MM, Ypenburg C, Van Bommel RJ, Boersma E, Dibbets-Schneider P, Stokkel MP, Schalij MJ, Berman DS, Germano G, Bax JJ

Unlabelled: The significance of left ventricular (LV) dyssynchrony for the prediction of response to cardiac resynchronization therapy (CRT) has been demonstrated. Parameters reflecting LV dyssynchrony (phase SD, histogram bandwidth) can be derived from gated myocardial perfusion SPECT (GMPS) using phase analysis. The feasibility of LV dyssynchrony assessment with phase analysis on GMPS using Quantitative Gated SPECT (QGS) software has not been demonstrated in patients undergoing CRT. The aim of... Abstract

Cited 105 times since 2009 (6.6 per year) source: EuropePMC

The American journal of cardiology, Volume 103, Issue 9, 1 1 2009, Pages 1295-1301 Role of multislice computed tomography in transcatheter aortic valve replacement. Wood DA, Tops LF, Mayo JR, Pasupati S, Schalij MJ, Humphries K, Lee M, Al Ali A, Munt B, Moss R, Thompson CR, Bax JJ, Webb JG

Transcatheter aortic valve replacement (TAVR) required precise knowledge of the anatomic dimensions and physical characteristics of the aortic valve, annulus, and aortic root. Most groups currently use angiography, transthoracic echocardiography (TTE), or transesophageal echocardiography (TEE) to assess aortic annulus dimensions and anatomy. However, multislice computed tomography (MSCT) may allow more detailed 3-dimensional assessment of the aortic root. Twenty-six patients referred for TAVR un... Abstract

Cited 66 times since 2009 (4.2 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 2, Issue 5, 1 1 2009, Pages 556-565 Assessment of mitral valve anatomy and geometry with multislice computed tomography. Delgado V, Tops LF, Schuijf JD, de Roos A, Brugada J, Schalij MJ, Thomas JD, Bax JJ

Objectives: The purpose of the present study was to assess the anatomy and geometry of the mitral valve by using 64-slice multislice computed tomography (MSCT). Background: Because it yields detailed anatomic information, MSCT may provide more insight into the underlying mechanisms of functional mitral regurgitation (FMR). Methods: In 151 patients, including 67 patients with heart failure (HF) and 29 patients with moderate to severe FMR, 64-slice MSCT coronary angiography was performed. The anat... Abstract

Cited 31 times since 2009 (2 per year) source: EuropePMC

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, Volume 10, Issue 3, 1 1 2009, Pages 285-290 An unusual cause of multiple organ dysfunction syndrome in the pediatric intensive care unit: hemophagocytic lymphohistiocytosis. Karapinar B, Yilmaz D, Balkan C, Akin M, Ay Y, Kvakli K

Objective: To report our experience in children with primary or secondary hemophagocytic lymphohistiocytosis (HLH) presented with multiple organ dysfunction syndrome (MODS) in pediatric intensive care unit (PICU). Design: The records of patients with a diagnosis of HLH and MODS between January 2005 and January 2008 were reviewed. The patients' characteristics, treatment modalities, and outcomes were assessed. Setting: PICU of Ege University Hospital. Patients/subjects: Twelve children who w... Abstract

Cited 11 times since 2009 (0.7 per year) source: EuropePMC

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 36, Issue 2, 25 4 2009, Pages 344-51; discussion 351 Pediatric tracheal reconstruction with pericardial patch and strips of autologous cartilage. Hazekamp MG, Koolbergen DR, Kersten J, Peper J, de Mol B, König-Jung A

Objective: To analyze the results of pediatric tracheal reconstruction with autologous pericardial patch and strips of cartilage. Methods: From September 2003 to February 2008 14 non-consecutive children were operated using pericardial patch augmentation of the trachea combined with external reinforcement with strips of autologous cartilage. Thin semicircular strips were fashioned from costal arch cartilage. Associated vascular rings, slings and aberrantly coursing arteries were treated first. C... Abstract

Cited 33 times since 2009 (2.1 per year) source: EuropePMC

Circulation. Cardiovascular quality and outcomes, Volume 2, Issue 4, 24 4 2009, Pages 338-343 Medication underuse during long-term follow-up in patients with peripheral arterial disease. Hoeks SE, Scholte op Reimer WJ, van Gestel YR, Schouten O, Lenzen MJ, Flu WJ, van Kuijk JP, Latour C, Bax JJ, van Urk H, Poldermans D

Background: Patients with peripheral arterial disease constitute a high-risk population. Guideline-recommended medical therapy use is therefore of utmost importance. The aims of our study were to establish the patterns of guideline-recommended medication use in patients with PAD at the time of vascular surgery and after 3 years of follow up, and to evaluate the effect of these therapies on long-term mortality in this patient group. Methods and results: Data on 711 consecutive patients with perip... Abstract

Cited 7 times since 2009 (0.4 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 297, Issue 1, 24 4 2009, Pages H233-7 Biventricular pacing-induced acute response in baroreflex sensitivity has predictive value for midterm response to cardiac resynchronization therapy. Gademan MG, van Bommel RJ, Borleffs CJ, Man S, Haest JC, Schalij MJ, van der Wall EE, Bax JJ, Swenne CA

In a previous study we demonstrated that the institution of biventricular pacing in chronic heart failure (CHF) acutely facilitates the arterial baroreflex. The arterial baroreflex has important prognostic value in CHF. We hypothesized that the acute response in baroreflex sensitivity (BRS) after the institution of cardiac resynchronization therapy (CRT) has predictive value for midterm response. One day after implantation of a CRT device in 33 CHF patients (27 male/6 female; age, 66.5 +/- 9.5 y... Abstract

Cited 10 times since 2009 (0.6 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 95, Issue 13, 22 4 2009, Pages 1038-1040 Lesions without calcium: lessons from CT angiography. Schuijf JD, van der Wall EE, Bax JJ

Abstract

Cited 8 times since 2009 (0.5 per year) source: EuropePMC

The American journal of cardiology, Volume 103, Issue 11, 22 4 2009, Pages 1592-1597 Relation of immediate decrease in ventricular septal strain after alcohol septal ablation for obstructive hypertrophic cardiomyopathy to long-term reduction in left ventricular outflow tract pressure gradient. van Ramshorst J, Mollema SA, Delgado V, van der Wall EE, Schalij MJ, Atsma DE, Bax JJ

Alcohol septal ablation (ASA) aims to decrease left ventricular outflow tract (LVOT) obstruction in patients with obstructive hypertrophic cardiomyopathy (HC). To date, no diagnostic variables at baseline are available to predict long-term success of the procedure. We hypothesized that an immediate decrease in septal longitudinal strain after ASA would be associated with sustained LVOT gradient decrease after 6 months. ASA was performed in 22 patients with HC and severe drug-refractory symptoms.... Abstract

Cited 50 times since 2009 (3.1 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 4, 17 3 2009, Pages 411-416 Risk of failure of transvenous implantable cardioverter-defibrillator leads. Borleffs CJ, van Erven L, van Bommel RJ, van der Velde ET, van der Wall EE, Bax JJ, Rosendaal FR, Schalij MJ

Background: Despite the positive effect on mortality in selected patients, implantable cardioverter-defibrillator therapy is also associated with potential malfunction of the implanted system. The present study provides the long-term lead failure rate in a large single-center cohort. Methods and results: Since 1992, a total of 2068 implantable cardioverter-defibrillator patients with 2161 defibrillation leads were prospectively collected. Data of the implant procedure and all follow-up visits we... Abstract

Cited 27 times since 2009 (1.7 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 3, 17 3 2009, Pages 249-257 Long-term improvement in left ventricular strain after successful catheter ablation for atrial fibrillation in patients with preserved left ventricular systolic function. Tops LF, Den Uijl DW, Delgado V, Marsan NA, Zeppenfeld K, Holman E, van der Wall EE, Schalij MJ, Bax JJ

Background: The effect of successful catheter ablation on left ventricular (LV) strain in patients with preserved LV systolic function is unknown. The aim of the present study was to assess the long-term effects of catheter ablation for atrial fibrillation (AF) on LV strain and strain rate in patients with preserved LV ejection fraction. Methods and results: In 78 patients undergoing catheter ablation for AF, speckle tracking strain imaging was performed to assess LV strain in 3 directions (radi... Abstract

Cited 13 times since 2009 (0.8 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 95, Issue 13, 9 2 2009, Pages 1085-1090 Tissue Doppler velocity is superior to strain imaging in predicting long-term cardiovascular events after cardiac resynchronisation therapy. Zhang Q, van Bommel RJ, Fung JW, Chan JY, Bleeker GB, Ypenburg C, Yip G, Liang YJ, Schalij MJ, Bax JJ, Yu CM

Objective: To examine the predictive value of systolic dyssynchrony measured by tissue Doppler velocity versus tissue Doppler strain imaging on long-term outcome after cardiac resynchronisation therapy (CRT). Design: Cohort study. Setting: Two university hospitals. Patients: Two hundred and thirty-nine patients (65 (SD 12) years, 76% males) who underwent CRT. Interventions: Baseline echocardiography with tissue Doppler imaging (TDI) and clinical follow-up for 37 (20) months. Main outcome measure... Abstract