8892 results
Cited 1 times since 2014 (0.1 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 22, Issue 3, 30 5 2015, Pages 408-418
Clinical topic: Nuclear imaging in hypertrophic cardiomyopathy.
Delgado V, Bax JJ
Non-invasive cardiac imaging plays a central role in the diagnosis and management of patients with hypertrophic cardiomyopathy. Transthoracic echocardiography is the imaging technique of first choice to evaluate wall thickness, left ventricular systolic and diastolic function, presence of left ventricular outflow tract obstruction, and abnormal mitral anatomy, whereas cardiac magnetic resonance provides additional information on tissue characterization (replacement fibrosis) using late gadoliniu...
Abstract
Cited 5 times since 2014 (0.5 per year)
source: EuropePMC
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association,
Volume 24, Issue 3, 24 4 2014, Pages 566-572
Practice variation in long-term secondary stroke prevention in The Netherlands.
van Schaik SM, de Vries BS, Weinstein HC, Visser MC, Van den Berg-Vos RM
Background: Stroke guidelines emphasize the importance of adequate vascular risk factor assessment and management in transient ischemic attack (TIA) and ischemic stroke patients, but it is not clear how these guidelines are applied in routine clinical practice. The limited data that are available indicate that TIA and ischemic stroke patients often do not receive the recommended interventions. The aim of this study was to investigate practice variations in long-term secondary stroke prevention i...
Abstract
Cited 23 times since 2014 (2.1 per year)
source: EuropePMC
The journals of gerontology. Series A, Biological sciences and medical sciences,
Volume 70, Issue 8, 24 4 2014, Pages 982-988
Associations Between Thrombin Generation and the Risk of Cardiovascular Disease in Elderly Patients: Results From the PROSPER Study.
Loeffen R, Winckers K, Ford I, Jukema JW, Robertson M, Stott DJ, Spronk HM, ten Cate H, Lowe GD, PROSPER Study Group
Background: Hypercoagulability may be an important contributor to the pathophysiology of atherosclerosis and atherothrombosis. As thrombin fulfills a central role in coagulation and links to several cellular mechanisms involved in arterial disease, we hypothesized that thrombin generation is associated with cardiovascular events in elderly patients. Methods: We studied the relationship between plasma thrombin generation and incident coronary heart disease (CHD) and stroke in the PROspective Stud...
Abstract
Cited 10 times since 2014 (0.9 per year)
source: EuropePMC
International journal of cardiology,
Volume 181, 23 4 2014, Pages 362-368
The prognostic impact of diastolic dysfunction in patients with chronic heart failure and post-acute myocardial infarction: Can age-stratified E/A ratio alone predict survival?
Rigolli M, Rossi A, Quintana M, Klein AL, Yu CM, Ghio S, Dini FL, Prior D, Troughton RW, Temporelli PL, Poppe KK, Doughty RN, Whalley GA, MeRGE Collaborators
Objective: To determine the prognostic implications of diastolic filling grades and identify whether age-stratified E/A ratio alone can identify patients at high risk of death post-AMI and HF. We hypothesized that in response to ageing and pathology, a normal E/A (>1) could be considered abnormal in patients post-AMI older than 65years, and that in patients with symptomatic HF, a normal E/A always represents advanced diastolic dysfunction. Methods and results: This is a sub-analysis of the Me...
Abstract
Cited 11 times since 2014 (1 per year)
source: EuropePMC
Biometrical journal. Biometrische Zeitschrift,
Volume 57, Issue 4, 20 3 2014, Pages 592-613
Covariate-adjusted measures of discrimination for survival data.
White IR, Rapsomaniki E, Emerging Risk Factors Collaboration
Motivation: Discrimination statistics describe the ability of a survival model to assign higher risks to individuals who experience earlier events: examples are Harrell's C-index and Royston and Sauerbrei's D, which we call the D-index. Prognostic covariates whose distributions are controlled by the study design (e.g. age and sex) influence discrimination and can make it difficult to compare model discrimination between studies. Although covariate adjustment is a standard procedure for...
Abstract
Cited 2 times since 2014 (0.2 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 8, 19 3 2014, Pages 424
Research topic: neuromorphic engineering systems and applications. A snapshot of neuromorphic systems engineering.
Delbruck T, van Schaik A, Hasler J
Abstract
Cited 2 times since 2014 (0.2 per year)
source: EuropePMC
Vascular,
Volume 23, Issue 6, 18 3 2014, Pages 661-662
Late onset acute occlusion of the subclavian artery after clavicle fracture.
van Schaik PM, de Borst GJ, Moll FL, Toorop RJ
Vascular injuries after a clavicle fracture are rare. The treatment remains, if possible, conservative. In case of life-threatening bleeding or limb ischemia, endovascular treatment is the treatment of choice. In this case report, we describe a patient who suffered a clavicle fracture five years before and now presented with acute invalidating claudication caused by an acute occlusion superimposed on a brachial artery stenosis. After unsuccessful thrombolytic therapy a surgical exploration of th...
Abstract
Cited 227 times since 2014 (20.9 per year)
source: EuropePMC
PLoS genetics,
Volume 10, Issue 12, 18 3 2014, Pages e1004776
Dissemination of cephalosporin resistance genes between Escherichia coli strains from farm animals and humans by specific plasmid lineages.
de Been M, Lanza VF, de Toro M, Scharringa J, Dohmen W, Du Y, Hu J, Lei Y, Li N, Tooming-Klunderud A, Heederik DJ, Fluit AC, Bonten MJ, Willems RJ, de la Cruz F, van Schaik W
Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for the treatment of human infections caused by Gram-negative bacteria, especially Escherichia coli. Worryingly, the incidence of human infections caused by third-generation cephalosporin-resistant E. coli is increasing worldwide. Recent studies have suggested that these E. coli strains, and their antibiotic resistance genes, can spread from food-producing animals, via the food-chain, to humans. However, thes...
Abstract
Cited 12 times since 2014 (1.1 per year)
source: Scopus
The American journal of cardiology,
Volume 115, Issue 5, 18 3 2014, Pages 664-669
Effect of aortic regurgitation following transcatheter aortic valve implantation on outcomes.
Ewe SH, Muratori M, van der Kley F, Pepi M, Delgado V, Tamborini G, Fusini L, de Weger A, Gripari P, Bartorelli A, Bax JJ, Marsan NA
The prognosis of aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) and the changes in AR grade over time remain unclear. This study evaluated the midterm survival associated with AR after TAVI and examined the evolution of AR over time and its effect on cardiac performance. Successful TAVI was performed in 314 patients (age 81 ± 7 years, 36% men). Serial transthoracic echocardiography and clinical assessment were available in 175 patients who survived >12 months....
Abstract
Cited 3 times since 2014 (0.3 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 149, Issue 4, 18 3 2014, Pages 968
Long-term follow-up after the arterial switch operation: Not as perfect as we would have hoped?
Hazekamp MG
Abstract
Cited 9 times since 2014 (0.8 per year)
source: EuropePMC
Veterinary research,
Volume 45, 17 3 2014, Pages 129
Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype.
Benedictus L, Otten HG, van Schaik G, van Ginkel WG, Heuven HC, Nielen M, Rutten VP, Koets AP
Bovine Neonatal Pancytopenia (BNP), a bleeding syndrome of neonatal calves, is caused by alloantibodies absorbed from the colostrum of particular cows. A commercial BVD vaccine is the likely source of alloantigens eliciting BNP associated alloantibodies. We hypothesized that the rare occurrence of BNP in calves born to vaccinated dams could be associated with genetic differences within dams and calves. We found that the development of BNP within calves was a heritable trait for dams, not for cal...
Abstract
Cited 8 times since 2014 (0.7 per year)
source: EuropePMC
Behavior modification,
Volume 39, Issue 3, 16 3 2014, Pages 390-412
Cognitive behavior therapy for anxiety in people with dementia: a clinician guideline for a person-centered approach.
Charlesworth G, Sadek S, Schepers A, Spector A
This article describes a 10-session cognitive-behavioral therapy (CBT) used in a randomized controlled trial with people with anxiety and mild-to-moderate dementia. The aim of the therapy is to reduce symptoms of anxiety by increasing a sense of safety and self-efficacy. The therapy is characterized by a person-centered approach to CBT, using individual tailoring to accommodate for cognitive deficits and other challenges. Three phases of therapy are described: (a) socialization to model (includi...
Abstract
Cited 4 times since 2014 (0.4 per year)
source: EuropePMC
Injury,
Volume 46, Issue 5, 16 3 2014, Pages 863-869
Impact of combat events on first responders: experiences of the armed conflict in Uruzgan, Afghanistan.
Hoencamp R, Idenburg FJ, Vermetten E, Tan E, Plat MC, Hoencamp E, Leenen LP, Hamming JF
Introduction: Care for battle casualties demands special skills from medics, nurses, and tactical commanders. To date, no inventory has been performed evaluating the first responders (medics, nurses and tactical commanders) around battle casualties. Method: This observational cohort study was conducted amongst the first responders (n=195) who were deployed to Southern Afghanistan (2009-2010) in three Marine companies. The survey focused on four main topics: (1) participants general background, (...
Abstract
Cited 63 times since 2014 (5.8 per year)
source: EuropePMC
Frontiers in immunology,
Volume 5, 12 2 2014, Pages 629
Is dosing of therapeutic immunoglobulins optimal? A review of a three-decade long debate in europe.
Kerr J, Quinti I, Eibl M, Chapel H, Späth PJ, Sewell WA, Salama A, van Schaik IN, Kuijpers TW, Peter HH
The consumption of immunoglobulins (Ig) is increasing due to better recognition of antibody deficiencies, an aging population, and new indications. This review aims to examine the various dosing regimens and research developments in the established and in some of the relevant off-label indications in Europe. The background to the current regulatory settings in Europe is provided as a backdrop for the latest developments in primary and secondary immunodeficiencies and in immunomodulatory indicati...
Abstract
Cited 78 times since 2014 (7.2 per year)
source: EuropePMC
PLoS pathogens,
Volume 10, Issue 12, 11 2 2014, Pages e1004569
Apoplastic venom allergen-like proteins of cyst nematodes modulate the activation of basal plant innate immunity by cell surface receptors.
Lozano-Torres JL, Wilbers RH, Warmerdam S, Finkers-Tomczak A, Diaz-Granados A, van Schaik CC, Helder J, Bakker J, Goverse A, Schots A, Smant G
Despite causing considerable damage to host tissue during the onset of parasitism, nematodes establish remarkably persistent infections in both animals and plants. It is thought that an elaborate repertoire of effector proteins in nematode secretions suppresses damage-triggered immune responses of the host. However, the nature and mode of action of most immunomodulatory compounds in nematode secretions are not well understood. Here, we show that venom allergen-like proteins of plant-parasitic ne...
Abstract
Cited 37 times since 2014 (3.4 per year)
source: EuropePMC
BMC nephrology,
Volume 15, 11 2 2014, Pages 197
Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients.
Buiten MS, de Bie MK, Bouma-de Krijger A, van Dam B, Dekker FW, Jukema JW, Rabelink TJ, Rotmans JI
Background: Dialysis patients suffer from a high burden of cardiovascular disease (CVD). Partly this is due to progressive deterioration of calcium-phosphate homeostasis. Previous studies suggested that besides FGF-23, low levels of Klotho, a protein linked to aging, might constitute a key factor in this detrimental relationship. The purpose of the present study was to determine the relationship between serum Klotho (sKlotho) and the presence of CVD in dialysis patients. Methods: Plasma levels o...
Abstract
Cited 8 times since 2014 (0.7 per year)
source: EuropePMC
World journal of urology,
Volume 33, Issue 10, 10 2 2014, Pages 1411-1417
Urinary cytokines in patients treated with intravesical mitomycin-C with and without hyperthermia.
Arends TJ, Falke J, Lammers RJ, Somford DM, Hendriks JC, de Weijert MC, Arentsen HC, van der Heijden AG, Oosterwijk E, Alfred Witjes J
Objectives: To explore whether urinary cytokine and chemokine (CK) levels differed between cold mitomycin-C (cold-MMC)-treated patients and chemohyperthermia (C-HT)-treated patients, to shed light on the possible molecular mechanisms that might explain the superior outcome of C-HT. Furthermore, CK-differences were explored between C-HT responders and C-HT non-responders. Methods: Twelve NMIBC patients were included. Nine received six-weekly C-HT, and three received four-weekly cold-MMC instillat...
Abstract
Cited 16 times since 2014 (1.5 per year)
source: EuropePMC
The International journal of social psychiatry,
Volume 61, Issue 6, 8 2 2014, Pages 530-538
The influence of acculturation on mental health and specialized mental healthcare for non-western migrants.
Nap A, van Loon A, Peen J, van Schaik DJ, Beekman AT, Dekker JJ
Background: The level of acculturation of migrants varies and is associated with variations in mental health. However, this association is complex and may differ among migrant groups. Aim: The aim of this study is to explore the association between acculturation, mental health and treatment effect. Methods: In a longitudinal cohort study of patients treated in specialized mental health facilities, different dimensions of acculturation (skills, social integration, traditions, norms/values and fee...
Abstract
Cited 9 times since 2014 (0.8 per year)
source: EuropePMC
Forensic science international,
Volume 248, 8 2 2014, Pages 101-112
Isotopic and elemental profiling of ammonium nitrate in forensic explosives investigations.
Brust H, Koeberg M, van der Heijden A, Wiarda W, Mügler I, Schrader M, Vivo-Truyols G, Schoenmakers P, van Asten A
Ammonium nitrate (AN) is frequently encountered in explosives in forensic casework. It is widely available as fertilizer and easy to implement in explosive devices, for example by mixing it with a fuel. Forensic profiling methods to determine whether material found on a crime scene and material retrieved from a suspect arise from the same source are becoming increasingly important. In this work, we have explored the possibility of using isotopic and elemental profiling to discriminate between di...
Abstract
Cited 31 times since 2014 (2.8 per year)
source: EuropePMC
Journal of molecular and cellular cardiology,
Volume 79, 5 1 2014, Pages 244-253
Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction.
Borgdorff MA, Koop AM, Bloks VW, Dickinson MG, Steendijk P, Sillje HH, van Wiechen MP, Berger RM, Bartelds B
Background: Right ventricular failure (RVF) due to pressure load is a major cause of death in congenital heart diseases and pulmonary hypertension. The mechanisms of RVF are unknown. We used an experimental approach based upon clinical signs of RVF to delineate functional and biological processes associated with RVF. Methods and results: Wistar rats were subjected to a pulmonary artery banding (PAB n=12) or sham surgery (CON, n=7). After 52±5days, 5/12 PAB rats developed clinical symptoms of RVF...
Abstract
