7153 results
Cited 38 times since 2010 (2.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 5, 23 4 2010, Pages 723-729
Relation of left ventricular twist and global strain with right ventricular dysfunction in patients after operative "correction" of tetralogy of fallot.
van der Hulst AE, Delgado V, Holman ER, Kroft LJ, de Roos A, Hazekamp MG, Blom NA, Bax JJ, Roest AA
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, globa...
Abstract
Cited 8 times since 2010 (0.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 5, 23 4 2010, Pages 682-687
Effect of cardiac resynchronization therapy on subendo- and subepicardial left ventricular twist mechanics and relation to favorable outcome.
Bertini M, Delgado V, Nucifora G, Marsan NA, Ng AC, Shanks M, Van Bommel RJ, Borleffs CJ, Ewe SH, Boriani G, Biffi M, Schalij MJ, Bax JJ
The analysis of left ventricular (LV) mechanics provides novel insights into the effects of cardiac resynchronization therapy (CRT) on LV performance. Currently, advances in speckle-tracking echocardiographic analysis have permitted the characterization of subendocardial and subepicardial LV twist. The aim of this study was to investigate the role of the acute changes in subendocardial and subepicardial LV twist for the prediction of midterm beneficial effects of CRT. A total of 84 patients with...
Abstract
Cited 4 times since 2010 (0.3 per year)
source: EuropePMC
The Journal of oral implantology,
Volume 37 Spec No, 21 3 2010, Pages 183-191
Prosthetic rehabilitation of edentulous ridges following alveolar distraction osteogenesis: clinical report of three cases.
Ergun G, Nagas IC, Yilmaz D, Ozturk M
Patients with complete edentulism who have insufficient bone for endosseous dental implant treatment present a challenge for dental practitioners. Distraction osteogenesis of the edentulous alveolar ridges is a process for augmentation of atrophic alveolar bone before dental implant placement. This clinical report describes the use of distraction osteogenesis and rehabilitation of patients with a fixed or removable implant-supported prosthesis to treat mandibular defects. Two female patients wit...
Abstract
Cited 14 times since 2010 (1 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 3, Issue 6, 21 3 2010, Pages 718-726
Predictive value of multislice computed tomography variables of atherosclerosis for ischemia on stress-rest single-photon emission computed tomography.
van Velzen JE, Schuijf JD, van Werkhoven JM, Herzog BA, Pazhenkottil AP, Boersma E, de Graaf FR, Scholte AJ, Kroft LJ, de Roos A, Stokkel MP, Jukema JW, Kaufmann PA, van der Wall EE, Bax JJ
Background: previous studies have shown that the presence of stenosis alone on multislice computed tomography (MSCT) has a limited positive predictive value for the presence of ischemia on myocardial perfusion imaging (MPI). The purpose of this study was to assess which variables of atherosclerosis on MSCT angiography are related to ischemia on MPI. Methods and results: both MSCT and MPI were performed in 514 patients. On MSCT, the calcium score, degree of stenosis (≥ 50% and ≥ 70% stenosis), an...
Abstract
Cited 66 times since 2010 (4.5 per year)
source: EuropePMC
Circulation,
Volume 122, Issue 5, 19 3 2010, Pages 470-477
Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility.
Vergeer M, Boekholdt SM, Sandhu MS, Ricketts SL, Wareham NJ, Brown MJ, de Faire U, Leander K, Gigante B, Kavousi M, Hofman A, Uitterlinden AG, van Duijn CM, Witteman JC, Jukema JW, Schadt EE, van der Schoot E, Kastelein JJ, Khaw KT, Dullaart RP, van Tol A, Trip MD, Dallinga-Thie GM
Background: In contrast to clear associations between variants in genes participating in low-density lipoprotein metabolism and cardiovascular disease risk, such associations for high-density lipoprotein (HDL)-related genes are not well supported by recent large studies. We aimed to determine whether genetic variants at the locus encoding phospholipid transfer protein (PLTP), a protein involved in HDL remodeling, underlie altered PLTP activity, HDL particle concentration and size, and cardiovasc...
Abstract
Cited 3 times since 2010 (0.2 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 12, Issue 11, 16 3 2010, Pages 1581-1588
Right ventricular stimulation threshold at ICD implant predicts device therapy in primary prevention patients with ischaemic heart disease.
Atary JZ, Borleffs CJ, van der Bom JG, Trines SA, Bootsma M, Zeppenfeld K, van Erven L, Schalij MJ
Aims: Myocardial excitability is known (amongst other reasons) to be related to the degree of ischaemia, contractile dysfunction and heart failure. It was hypothesized that the right ventricular (RV) stimulation threshold has prognostic value with respect to the occurrence of ventricular arrhythmias (VAs) and patient survival in recipients of an implantable cardioverter defibrillator (ICD). Methods and results: Ischaemic heart disease patients receiving an ICD at Leiden University Medical Center...
Abstract
Cited 38 times since 2010 (2.6 per year)
source: EuropePMC
Radiology,
Volume 256, Issue 3, 15 3 2010, Pages 724-734
Tetralogy of fallot: 3D velocity-encoded MR imaging for evaluation of right ventricular valve flow and diastolic function in patients after correction.
van der Hulst AE, Westenberg JJ, Kroft LJ, Bax JJ, Blom NA, de Roos A, Roest AA
Purpose: To evaluate three-dimensional (3D) velocity-encoded (VE) magnetic resonance (MR) imaging, as compared with two-dimensional (2D) VE MR imaging, for assessment of pulmonary valve (PV) and tricuspid valve (TV) flow, with planimetry as the reference standard, and to evaluate diastolic function in patients with a corrected tetralogy of Fallot (TOF). Materials and methods: Local institutional review board approval was obtained, and patients or their parents gave informed consent. Twenty-five...
Abstract
Cited 39 times since 2010 (2.7 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 3, Issue 5, 14 2 2010, Pages 623-631
Pulmonary vascular resistance, collateral flow, and ventricular function in patients with a Fontan circulation at rest and during dobutamine stress.
Schmitt B, Steendijk P, Ovroutski S, Lunze K, Rahmanzadeh P, Maarouf N, Ewert P, Berger F, Kuehne T
Background: The role, interplay, and relative importance of the multifactorial hemodynamic and myocardial mechanisms causing dysfunction of the Fontan circulation remain incompletely understood. Methods and results: Using an MRI catheterization technique, we performed a differential analysis of pulmonary vascular resistance and aortopulmonary collateral blood flow in conjunction with global ventricular pump function, myocontractility (end-systolic pressure-volume relation), and diastolic complia...
Abstract
Cited 104 times since 2010 (7.1 per year)
source: EuropePMC
Nature genetics,
Volume 42, Issue 8, 11 2 2010, Pages 688-691
Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction.
Bezzina CR, Pazoki R, Bardai A, Marsman RF, de Jong JSSG, Blom MT, Scicluna BP, Jukema JW, Bindraban NR, Lichtner P, Pfeufer A, Bishopric NH, Roden DM, Meitinger T, Chugh SS, Myerburg RJ, Jouven X, Kääb S, Dekker LRC, Tan HL, Tanck MWT, Wilde AAM
Sudden cardiac death from ventricular fibrillation during acute myocardial infarction is a leading cause of total and cardiovascular mortality. To our knowledge, we here report the first genome-wide association study for this trait, conducted in a set of 972 individuals with a first acute myocardial infarction, 515 of whom had ventricular fibrillation and 457 of whom did not, from the Arrhythmia Genetics in The Netherlands (AGNES) study. The most significant association to ventricular fibrillati...
Abstract
Cited 2 times since 2010 (0.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 27, Issue 7, 11 2 2010, Pages 1011-1014
IVUS detects more coronary calcifications than MSCT; matter of both resolution and cross-sectional assessment?
van der Wall EE, de Graaf FR, van Velzen JE, Jukema JW, Bax JJ, Schuijf JD
Abstract
The international journal of cardiovascular imaging,
Volume 27, Issue 1, 8 2 2010, Pages 59-63
Evidence of scar tissue: contra-indication to cardiac resynchronization therapy?
van der Wall EE, Schalij MJ, Verwey HF, Bax JJ
Abstract
European heart journal,
Volume 31, Issue 19, 8 2 2010, Pages 2323-2325
Changes in functional mitral regurgitation after cardiac resynchronization therapy.
Marsan NA, Bax JJ
Abstract
Cited 523 times since 2010 (35.7 per year)
source: EuropePMC
Nature genetics,
Volume 42, Issue 8, 4 1 2010, Pages 665-667
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.
Nikoloski G, Langemeijer SM, Kuiper RP, Knops R, Massop M, Tönnissen ER, van der Heijden A, Scheele TN, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH
In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant genes on chromosome 7 are unknown. We report here that EZH2, located at 7q36.1, is frequently targeted in MDS. Analysis of EZH2 deletions, missense and frameshift mutations strongly suggests that EZH2 is a tumor suppressor. As EZH2 functions as a histone methyltransferase, abnormal histone modification may contribute to epigenetic deregulation in MDS.
Abstract
Cited 123 times since 2010 (8.4 per year)
source: EuropePMC
European heart journal,
Volume 31, Issue 16, 2 1 2010, Pages 1975-1984
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation.
Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E
Aims: Westernized countries face a growing burden of cardiovascular calcification and osteoporosis. Despite its vast clinical significance, the precise nature of this reciprocal relationship remains obscure. We hypothesize that cardiovascular calcification progresses with inflammation and inversely correlates with bone tissue mineral density (TMD). Methods and results: Arterial, valvular, and bone metabolism were visualized using near-infrared fluorescence (NIRF) molecular imaging agents, target...
Abstract
Cited 47 times since 2010 (3.2 per year)
source: EuropePMC
Radiology,
Volume 256, Issue 1, 1 1 2010, Pages 83-92
Diabetes: prognostic value of CT coronary angiography--comparison with a nondiabetic population.
Van Werkhoven JM, Cademartiri F, Seitun S, Maffei E, Palumbo A, Martini C, Tarantini G, Kroft LJ, de Roos A, Weustink AC, Jukema JW, Ardissino D, Mollet NR, Schuijf JD, Bax JJ
Purpose: To evaluate the prognostic value of multidetector computed tomographic (CT) coronary angiography in a diabetic population known to have or suspected of having coronary artery disease (CAD) compared with that in nondiabetic individuals. Materials and methods: Institutional review board approval and patient informed consent were obtained. Three hundred thirteen patients with type 2 diabetes mellitus (DM) and 303 patients without DM underwent unenhanced 64-detector row CT, at which a calci...
Abstract
Cited 37 times since 2010 (2.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 3, Issue 7, 1 1 2010, Pages 699-709
Automated quantification of stenosis severity on 64-slice CT: a comparison with quantitative coronary angiography.
Boogers MJ, Schuijf JD, Kitslaar PH, van Werkhoven JM, de Graaf FR, Boersma E, van Velzen JE, Dijkstra J, Adame IM, Kroft LJ, de Roos A, Schreur JH, Heijenbrok MW, Jukema JW, Reiber JH, Bax JJ
Objectives: This study sought to demonstrate the feasibility of a dedicated algorithm for automated quantification of stenosis severity on multislice computed tomography in comparison with quantitative coronary angiography (QCA). Background: Limited information is available on quantification of coronary stenosis, and previous attempts using semiautomated approaches have been suboptimal. Methods: In patients who had undergone 64-slice computed tomography and invasive coronary angiography, the mos...
Abstract
Cited 73 times since 2010 (5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 56, Issue 3, 1 1 2010, Pages 225-233
Effects of hepatic triglyceride content on myocardial metabolism in type 2 diabetes.
Rijzewijk LJ, Jonker JT, van der Meer RW, Lubberink M, de Jong HW, Romijn JA, Bax JJ, de Roos A, Heine RJ, Twisk JW, Windhorst AD, Lammertsma AA, Smit JW, Diamant M, Lamb HJ
Objectives: The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in type 2 diabetes mellitus (T2DM). Background: Heart disease is the leading cause of mortality in T2DM. Central obesity and hepatic steatosis, both hallmark abnormalities in T2DM, have been related to increased risk of heart disease. Methods: Sixty-one T2DM patients underwent myocardial perfusion and substrate metabolism measurements by posit...
Abstract
Cited 8 times since 2010 (0.5 per year)
source: EuropePMC
American journal of nephrology,
Volume 32, Issue 2, 1 1 2010, Pages 163-168
Elevated preoperative phosphorus levels are an independent risk factor for cardiovascular mortality.
van Kuijk JP, Flu WJ, Chonchol M, Valentijn TM, Verhagen HJ, Bax JJ, Poldermans D
Background/aims: Serum phosphorus levels have been associated with adverse long-term outcome in several populations, however, no prior studies evaluated short-term postoperative outcome. The present study evaluated the predictive value of phosphorus levels on 30-day outcome after vascular surgery. Methods: The study included patients scheduled for major vascular surgery (aortic aneurysm repair, lower extremity revascularization or carotid surgery), divided into four quartiles based on the preope...
Abstract
Current cardiology reports,
Volume 12, Issue 4, 1 1 2010, Pages 286-294
Preoperative evaluation of patients with possible coronary artery disease.
Flu WJ, van Kuijk JP, Hoeks S, Bax JJ, Poldermans D
During noncardiac surgery, patients may be at risk for developing cardiac events, related to underlying coronary artery disease. Therefore, perioperative cardiac complications remain an area of clinical interest and concern in patients undergoing noncardiac surgery. Over the years, perioperative risk assessment has evolved significantly to detect surgical patients with myocardium at risk due the coronary artery disease. In addition, many efforts have been made to reduce the cardiac risk of patie...
Abstract
Cited 21 times since 2010 (1.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 1, 1 1 2010, Pages 73-77
Effect of cardiac resynchronization therapy on cerebral blood flow.
van Bommel RJ, Marsan NA, Koppen H, Delgado V, Borleffs CJ, Ypenburg C, Bertini M, Schalij MJ, Bax JJ
Decreased cerebral blood flow is frequently observed in patients with heart failure, and this could be the result of impaired cardiac systolic function. Cardiac resynchronization therapy (CRT) improves cardiac function and heart failure symptoms in selected patients. The effects of CRT on cerebral blood flow have not been previously evaluated. In the present study, left ventricular systolic function and cerebral blood flow were assessed in 35 patients with heart failure, before and 6 months afte...
Abstract
