Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6143 results
Cited 9 times since 2019 (1.5 per year) source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD, Volume 29, Issue 7, 28 4 2019, Pages 728-735 The role of inflammation in the association between overall and visceral adiposity and subclinical atherosclerosis. Christen T, Trompet S, Rensen PCN, Willems van Dijk K, Lamb HJ, Jukema JW, Rosendaal FR, le Cessie S, de Mutsert R
Background and aims: Inflammation may underlie the association between obesity, atherosclerosis and cardiovascular disease. We investigated to what extent markers of inflammation mediate associations between overall and visceral body fat and subclinical atherosclerosis. Methods and results: In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study we estimated total body fat (TBF) by bio-impedance analysis, carotid artery intima media thickness (cIMT) by ultrasound, C-rea... Abstract
Cited 44 times since 2019 (7.3 per year) source: EuropePMC
Blood reviews, Volume 35, 25 4 2019, Pages 59-67 Atrial fibrillation and cancer - An unexplored field in cardiovascular oncology. Chu G, Versteeg HH, Verschoor AJ, Trines SA, Hemels MEW, Ay C, Huisman MV, Klok FA
An increasing body of evidence suggests an association between cancer and atrial fibrillation (AF). The exact magnitude and underlying mechanism of this association are however unclear. Cancer-related inflammation, anti-cancer treatment and other cancer-related comorbidities are proposed to affect atrial remodelling, increasing the susceptibility of cancer patients for developing AF. Moreover, cancer is assumed to modify the risk of thromboembolisms and bleeding. A thorough and adequate understa... Abstract
International journal of cardiology, Volume 287, 22 4 2019, Pages 211 Corrigendum to "Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients" [Int. J. Cardiol. 124 (2008) 166-171]. van der Hoeven BL, Pires NMM, Warda HM, Putter H, Quax PHA, Schalij MJ, Jukema JW
Cited 14 times since 2019 (2.3 per year) source: EuropePMC
Circulation. Genomic and precision medicine, Volume 12, Issue 4, 21 3 2019, Pages e002470 Subsequent Event Risk in Individuals With Established Coronary Heart Disease. Patel RS, Tragante V, Schmidt AF, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Allayee H, Almgren P, Alver M, Baranova EV, Behloui H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dubé MP, Dufresne L, Eriksson N, Foco L, Scholz M, Gijsberts CM, Glinge C, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kotti S, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, Van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Al Ali L, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Engstrøm T, Fitzpatrick N, Fox K, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton-Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ
Background: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. Methods: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD, or a mixture of both at baseline. All studies collected biological samples and followed-up study p... Abstract
Cited 14 times since 2019 (2.3 per year) source: EuropePMC
Circulation. Genomic and precision medicine, Volume 12, Issue 4, 21 3 2019, Pages e002471 Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events. Patel RS, Schmidt AF, Tragante V, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Dubé MP, Allayee H, Almgren P, Alver M, Baranova EV, Behlouli H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dufresne L, Eriksson N, Foco L, Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Fitzpatrick N, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ, Algra A, Andreassi MG, Ardissino D, Arsenault BJ, Balla
Background: Genetic variation at chromosome 9p21 is a recognized risk factor for coronary heart disease (CHD). However, its effect on disease progression and subsequent events is unclear, raising questions about its value for stratification of residual risk. Methods: A variant at chromosome 9p21 (rs1333049) was tested for association with subsequent events during follow-up in 103 357 Europeans with established CHD at baseline from the GENIUS-CHD (Genetics of Subsequent Coronary Heart Disease) Co... Abstract
Cited 2 times since 2019 (0.3 per year) source: EuropePMC
Frontiers in physiology, Volume 10, 19 3 2019, Pages 225 Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy? Grewal N, Gittenberger-de Groot AC
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
JMIR cardio, Volume 3, Issue 1, 19 3 2019, Pages e9894 Mobile Health for Central Sleep Apnea Screening Among Patients With Stable Heart Failure: Single-Cohort, Open, Prospective Trial. Treskes RW, Maan AC, Verwey HF, Schot R, Beeres SLMA, Tops LF, Tops LF, Van Der Velde ET, Schalij MJ, Slats AM
Background: Polysomnography is the gold standard for detection of central sleep apnea in patients with stable heart failure. However, this procedure is costly, time consuming, and a burden to the patient and therefore unsuitable as a screening method. An electronic health (eHealth) app to measure overnight oximetry may be an acceptable screening alternative, as it can be automatically analyzed and is less burdensome to patients. Objective: This study aimed to assess whether overnight pulse oxime... Abstract
Pacing and clinical electrophysiology : PACE, Volume 42, Issue 6, 19 3 2019, Pages 759 Atrial fibrillation history impact on catheter ablation outcome. Stabile G, Trines SA, Blomström Lundqvist C, ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry investigators
Cited 69 times since 2019 (11.5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 74, Issue 9, 18 3 2019, Pages 1167-1176 Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome: ODYSSEY OUTCOMES Trial. Jukema JW, Szarek M, Zijlstra LE, de Silva HA, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Karpov Y, Moryusef A, Pordy R, Prieto JC, Roe MT, White HD, Zeiher AM, Schwartz GG, Steg PG, ODYSSEY OUTCOMES Committees and Investigators
Background: Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. Objectives: This pre-specified analysis from ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) determined whether polyvascular di... Abstract
Cited 17 times since 2019 (2.8 per year) source: EuropePMC
The British journal of surgery, Volume 106, Issue 5, 18 3 2019, Pages 523-533 Meta-analysis of long-term survival after elective endovascular or open repair of abdominal aortic aneurysm. Bulder RMA, Bastiaannet E, Hamming JF, Lindeman JHN
Background: Endovascular aneurysm repair (EVAR) has become the preferred strategy for elective repair of abdominal aortic aneurysm (AAA) for many patients. However, the superiority of the endovascular procedure has recently been challenged by reports of impaired long-term survival in patients who underwent EVAR. A systematic review of long-term survival following AAA repair was therefore undertaken. Methods: A systematic review was performed according to PRISMA guidelines. Articles reporting sho... Abstract
Cited 55 times since 2019 (9.1 per year) source: EuropePMC
Circulation, Volume 139, Issue 23, 18 3 2019, Pages 2628-2638 Prophylactic Use of Implantable Cardioverter-Defibrillators in the Prevention of Sudden Cardiac Death in Dialysis Patients. Jukema JW, Timal RJ, Rotmans JI, Hensen LCR, Buiten MS, de Bie MK, Putter H, Zwinderman AH, van Erven L, Krol-van Straaten MJ, Hommes N, Gabreëls B, van Dorp W, van Dam B, Herzog CA, Schalij MJ, Rabelink TJ, ICD2 Trial Investigators
Background: Patients with end-stage renal disease who are undergoing dialysis are reported to be at high risk of sudden cardiac death (SCD), and to date, no therapy has been shown to be effective in reducing this risk. The feasibility and value of prophylactic implantable cardioverter-defibrillator (ICD) implantation to prevent SCD is uncertain. Methods: We conducted the ICD2 trial (Implantable Cardioverter-Defibrillator in Dialysis Patients), a prospective, randomized, controlled study investig... Abstract
Cited 111 times since 2019 (18.5 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 13, Issue 1 Pt 1, 17 3 2019, Pages 97-105 1-Year Impact on Medical Practice and Clinical Outcomes of FFR<sub>CT</sub>: The ADVANCE Registry. Patel MR, Nørgaard BL, Fairbairn TA, Nieman K, Akasaka T, Berman DS, Raff GL, Hurwitz Koweek LM, Pontone G, Kawasaki T, Sand NPR, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, Mullen S, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Leipsic J
Objectives: The 1-year data from the international ADVANCE (Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care) Registry of patients undergoing coronary computed tomography angiography (CTA) was used to evaluate the relationship of fractional flow reserve derived from coronary CTA (FFRCT) with downstream care and clinical outcomes. Background: Guidelines for management of chest pain using noninvasive imaging pathways are based on short- to intermediate-term outcomes. Methods: Pati... Abstract
Cited 4 times since 2019 (0.7 per year) source: EuropePMC
Journal of cardiac surgery, Volume 34, Issue 5, 13 2 2019, Pages 285-292 Outcomes after Ross procedure in adult patients: A meta-analysis and microsimulation. Sibilio S, Koziarz A, Belley-Côté EP, McClure GR, MacIsaac S, Reza SJ, Um KJ, Lengyel A, Mendoza P, Alsagheir A, Alraddadi H, Gupta S, Schneider AW, Patel PM, Brown JW, Chu MWA, Peterson MD, Ouzounian M, Paparella D, El-Hamamsy I, Whitlock RP
Objective: We conducted a meta-analysis to estimate the risk of adverse events, life expectancy, and event-free life expectancy after the Ross procedure in adults. Methods: We searched databases for reports evaluating the Ross procedure in patients aged more than or equal to 16 years of age. A microsimulation model was used to evaluate age- and gender-specific life expectancy for patients undergoing the Ross procedure. Results: Data were pooled from 63 articles totaling 19 155 patients from 20 c... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Heart, lung & circulation, Volume 28, Issue 9, 8 2 2019, Pages 1384-1399 Echocardiography in Transcatheter Aortic Valve Replacement. Vollema EM, Delgado V, Bax JJ
Transcatheter aortic valve replacement (TAVR) is a safe and efficient alternative for surgical valve aortic replacement in patients with symptomatic severe aortic stenosis who are inoperable or have a high risk for surgery. Randomised clinical trials have shown that TAVR is not inferior to surgical aortic valve replacement in intermediate-risk patients and ongoing trials will demonstrate the effects of TAVR in asymptomatic severe aortic stenosis patients and in patients with heart failure and mo... Abstract
Cited 6 times since 2019 (1 per year) source: EuropePMC
The American journal of medicine, Volume 132, Issue 8, 8 2 2019, Pages 921-925 The Medical Profession, Industry, and Continuing Medical Education: Finding the Balance That's Right for Patients. Kearney P, Simoons M, Ryden L, Kirchhof P, Pries A, O'Morain C, Bax JJ
Provision and participation in formal external continuing medical education (CME) is costly. Employer or state support of CME is the exception rather than the rule. The medical industry has supported both providers and consumers of educational activities, leading to concerns of commercial bias. Recent medical industry initiatives in Europe to improve the transparency of the relationship between industry and the profession, including the field of medical education, have had the paradoxical effect... Abstract
The Lancet. Infectious diseases, Volume 19, Issue 4, 4 1 2019, Pages 347-348 How fluoroquinolones poison the neighbourhood. van Werkhoven CH, Bootsma M, Bonten M
Cited 79 times since 2019 (13 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 3, 1 1 2019, Pages 491-499 Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications. Prihadi EA, Delgado V, Leon MB, Enriquez-Sarano M, Topilsky Y, Bax JJ
Tricuspid regurgitation (TR) is classified according to different morphologic types based on the underlying mechanisms: primary, secondary, and isolated TR. Primary TR is caused by an anatomical abnormality of the tricuspid valve apparatus. Secondary TR is caused by dilation of the tricuspid valve annulus, related to right ventricular (RV), or right atrial remodeling and increased RV pressures (often secondary to left-sided heart disease). Isolated TR can exist in patients without increased RV p... Abstract
European heart journal, Volume 40, Issue 11, 1 1 2019, Pages 867 Dr Shahbudin H. Rahimtoola: the mentor. Bax JJ
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
Advances in physiology education, Volume 43, Issue 1, 1 1 2019, Pages 7-14 Informing the uninformed: a multitier approach to uncover students' misconceptions on cardiovascular physiology. Versteeg M, Wijnen-Meijer M, Steendijk P
Misconceptions about physiology are a major threat to accurate scientific and clinical reasoning in medical education. Awareness is often mentioned as a prerequisite to achieve conceptual understanding; however, students are frequently unaware of their incorrect understanding. We explored the multitier approach as a tool to obtain insight into students' awareness and misconceptions regarding cardiovascular physiology. Biomedical sciences students ( N = 81) participated in a diagnostic multi... Abstract
Cited 10 times since 2019 (1.7 per year) source: EuropePMC
Lancet (London, England), Volume 393, Issue 10175, 1 1 2019, Pages 1056-1070 Multimodality imaging in ischaemic heart failure. Bax JJ, Di Carli M, Narula J, Delgado V
In heart failure, extensive evaluation with modern non-invasive imaging modalities is needed to assess causes, pathophysiology, and haemodynamics, to determine prognosis and consider therapeutic options. This systematic evaluation includes a stepwise assessment of left ventricular size and function, the presence and severity of coronary artery disease, mitral regurgitation, pulmonary hypertension, right ventricular dilation and dysfunction, and tricuspid regurgitation. Based on this imaging-deri... Abstract