Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6173 results
Cited 25 times since 1988 (0.7 per year) source: EuropePMC
World journal of surgery, Volume 12, Issue 4, 1 1 1988, Pages 503-508 Prognostic value of nuclear DNA content in papillary and follicular thyroid cancer. Hamming JF, Schelfhout LJ, Cornelisse CJ, van de Velde CJ, Goslings BM, Hermans J, Fleuren GJ
Cited 66 times since 1988 (1.8 per year) source: EuropePMC
Circulation research, Volume 62, Issue 6, 1 1 1988, Pages 1247-1258 Sensitivity of left ventricular end-systolic pressure-volume relation to type of loading intervention in dogs. Baan J, Van der Velde ET
The influence of different types of loading intervention on the resulting end-systolic pressure-volume relation (ESPVR) of the left ventricle in situ was investigated in anesthetized open-chest dogs. Left ventricular volume was measured by conductance catheter and pressure was measured by tip-micromanometer. Two loading interventions were applied: a pressure intervention (INp) by gradually occluding the descending aorta and a volume intervention (INv) by rapidly infusing 180 ml blood into the ve... Abstract
Cited 2 times since 1988 (0.1 per year) source: EuropePMC
The Thoracic and cardiovascular surgeon, Volume 36, Issue 3, 1 1 1988, Pages 137-140 Assessment of hypertrophy in myocardial biopsies taken during correction of congenital heart disease. Bogers AJ, van der Laarse A, Vliegen HW, Quaegebeur JM, Hollaar L, Egas JM, Cornelisse CJ, Rohmer J, Huysmans HA
Myocardial biopsies were obtained from 27 patients undergoing corrective cardiac surgery for congenital heart disease. Normal hearts of 18 autopsied patients were used as reference. The biopsy material was assessed for desoxyribonucleic acid (DNA) concentration and ploidy profile of cell nuclei in order to quantitate myocardial hypertrophy at the time of operation. DNA-concentration decreased significantly with age (r = -0.76; p less than 0.001). Ploidy profile of myocardial nuclei correlated wi... Abstract
Cited 2 times since 1988 (0.1 per year) source: EuropePMC
The American journal of physiology, Volume 254, Issue 6 Pt 2, 1 1 1988, Pages H1113-24 Identifiability of left ventricular end-systolic pressure-volume relationships. van der Linden LP, van der Velde ET, Bruschke AV, Baan J
A widely accepted model of the left ventricle (LV) consisting of a time-varying elastance and a nonlinear internal resistance was investigated to make inferences about the identifiability of its parameters by means of simulated experiments. We aimed to retrieve maximum elastance (Emax) and dead volume (Vd) by the usual slope method or end-systolic pressure-volume relations (ESPVR) and by model-based parameter identification. The ESPVR deviated increasingly from the assigned values with increasin... Abstract
Laryngologie, Rhinologie, Otologie, Volume 67, Issue 6, 1 1 1988, Pages 286-288 [Vestibular apparatus and hereditary hearing impairment]. Lamprecht A, Keulen M
Vestibular function tests in 33 cases of hereditary monosymptomatic symmetric sensorineural hearing loss do not show any significantly reduced excitability, but a mild difference between the groups with and without progression. A positive correlation is seen with the age of the children. Abstract
Cited 347 times since 1988 (9.3 per year) source: EuropePMC
Circulation research, Volume 62, Issue 2, 1 1 1988, Pages 395-410 Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs. Rensma PL, Allessie MA, Lammers WJ, Bonke FI, Schalij MJ
We calculated the wavelength of the atrial impulse in chronically instrumented conscious dogs by measuring both conduction velocity and refractory period: wavelength = refractory period X conduction velocity. Implantation of multiple stimulating and recording electrodes allowed wavelength determination at four different areas: the right and left parts of Bachmann's bundle and the free walls of the right and left atria. During programmed electrical stimulation, three types of arrhythmias wer... Abstract
Cited 19 times since 1988 (0.5 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 24, Issue 2, 1 1 1988, Pages 325-330 Differentiated thyroid cancer: a stage adapted approach to the treatment of regional lymph node metastases. Hamming JF, van de Velde CJ, Fleuren GJ, Goslings BM
The controversy in the management of regional lymph nodes in patients with differentiated thyroid cancer is discussed on the basis of a review of the literature. Since no prospective studies have yet compared limited dissections ('node picking') with more extensive dissections [(modified) radical neck dissection], a retrospective analysis was performed using two patient groups in which patients were managed differently with regard to the preoperative diagnosis and treatment of regional... Abstract
Cited 62 times since 1988 (1.7 per year) source: EuropePMC
European journal of cancer & clinical oncology, Volume 24, Issue 2, 1 1 1988, Pages 331-337 Multivariate analysis of survival in differentiated thyroid cancer: the prognostic significance of the age factor. Schelfhout LJ, Creutzberg CL, Hamming JF, Fleuren GJ, Smeenk D, Hermans J, van de Velde CJ, Goslings BM
A retrospective analysis of tumour and patient characteristics was performed in 202 patients with papillary (n = 132) or follicular (n = 70) thyroid carcinoma, in order to identify prognostic factors related to survival. The following facts were found to be unfavourably related to survival: follicular histology, extrathyroidal growth of the primary tumour (stage pT4), regional lymph node involvement (stages pN1-3), presence of distant metastases at diagnosis (stage pM1), male sex (in papillary c... Abstract
Cited 3 times since 1988 (0.1 per year) source: EuropePMC
Journal of pharmaceutical and biomedical analysis, Volume 6, Issue 6-8, 1 1 1988, Pages 895-902 Evaluation of sample work-up methods and internal standards for the determination of catecholamines in urine by HPLC with electrochemical detection. Claeys M, Schepers A, Dillen L, De Potter WP
Two sample work-up methods: (I) one consisting of adsorption of the catecholamines onto alumina followed by ion pair extraction and (II) another consisting of isolation by cation exchange and subsequent adsorption onto alumina, have been evaluated for the assay of urinary catecholamines by means of HPLC with electrochemical detection. With the aim of achieving high precision, two internal standards, i.e. dihydroxybenzylamine and epinine, have been compared. The results indicate that clean HPLC c... Abstract
Ankara Universitesi Dis Hekimligi Fakultesi dergisi = The Journal of the Dental Faculty of Ankara University, Volume 14, Issue 3, 1 1 1987, Pages 303-306 [The influence of Visco-Gel and Voco-Pak tissue conditioning materials on the bacterial lesion floras of the patients with vestibuloplasties]. Misirligil A, Güngör N, Yilmaz D
Cited 17 times since 1987 (0.4 per year) source: EuropePMC
Research communications in chemical pathology and pharmacology, Volume 57, Issue 1, 1 1 1987, Pages 15-32 Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. Knufman NM, van der Laarse A, Vliegen HW, Brinkman CJ
Administration of a single high dose or multiple low doses of isoproterenol (ISO) to rats induces myocardial necrosis and cardiac hypertrophy. To assess the extent of necrosis we measured myocardial activities of creatine kinase (CK) and aspartate aminotransferase (AST) in the first days after ISO-treatment. After a single high dose and multiple low doses of ISO, necrosis was 10% and 25%, respectively. To quantify the degree of hypertrophy we measured heart weight and myocyte volume, and calcula... Abstract
Cited 28 times since 1987 (0.7 per year) source: EuropePMC
Cardiovascular research, Volume 21, Issue 5, 1 1 1987, Pages 352-357 Morphometric quantification of myocyte dimensions validated in normal growing rat hearts and applied to hypertrophic human hearts. Vliegen HW, van der Laarse A, Huysman JA, Wijnvoord EC, Mentar M, Cornelisse CJ, Eulderink F
To obtain quantitative information on changes in myocyte size in hearts with increased myocardial mass light microscopical morphometry was used in fixed and stained myocardial tissue sections. A modification of the azan staining procedure made longitudinal (sarcolemma) and transverse (intercalated discs) boundaries visible with a contrast that allowed morphometric analysis. The method was validated in left ventricular tissue of rats ranging in age from 4 to 17 weeks. Myocyte width, cut surface a... Abstract
Ankara Universitesi Dis Hekimligi Fakultesi dergisi = The Journal of the Dental Faculty of Ankara University, Volume 14, Issue 2, 1 1 1987, Pages 209-212 [Odontogenic myxoma]. Türker M, Güngör N, Yücetaş S, Yilmaz D, Günhan O
Cited 8 times since 1987 (0.2 per year) source: EuropePMC
Cardiovascular research, Volume 21, Issue 3, 1 1 1987, Pages 223-229 Relation between ventricular DNA content and number of myocytes and non-myocytes in hearts of normotensive and spontaneously hypertensive rats. van der Laarse A, Bloys van Treslong CH, Vliegen HW, Ricciardi L
Myocardial DNA concentration and ventricular weight were measured in the hearts of normal and spontaneously hypertensive rats varying in age from 1 day to 1 year and the ventricular DNA content calculated. A linear relation between ventricular DNA content and ventricular weight was observed in both rat strains. This linear relation was deduced theoretically, assuming that the number of ventricular non-myocytes per heart was proportional to ventricular weight and that the number of ventricular my... Abstract
Hormone research, Volume 27, Issue 4, 1 1 1987, Pages 195-199 Bromocriptine is unable to suppress TRH-stimulated beta-endorphin/beta-lipotropin and cortisol secretion in normal pregnant women after delivery. Lamberts SW, Angement R, van der Heijden A, Wladimiroff JW, Hackeng WH, de Jong FH
The course of plasma beta-endorphin/beta-lipotropin, cortisol and prolactin (PRL) levels was followed from 0.5 till 5 h after normal delivery in 13 healthy women. Six subjects who did not want to breast-feed their child received 2.5 mg bromocriptine orally 1 h after delivery. After 3 h the effect of the intravenous administration of 200 micrograms thyrotropin-releasing hormone (TRH) was also measured. Elevated plasma beta-endorphin and cortisol levels decreased after delivery in a (log) linear f... Abstract
Cited 1 times since 1986 (0 per year) source: EuropePMC
Bollettino della Societa italiana di biologia sperimentale, Volume 62, Issue 1, 1 1 1986, Pages 89-93 [Mechanical and structural variations in the hypertrophic myocardium of trained swimming rats]. Ricciardi L, ter Keurs HE, vd Laarse A, Vliegen HW
Cited 9 times since 1986 (0.2 per year) source: EuropePMC
Histochemistry, Volume 84, Issue 4-6, 1 1 1986, Pages 348-354 Methodological aspects of flow cytometric analysis of DNA polyploidy in human heart tissue. Vliegen HW, Vossepoel AM, van der Laarse A, Eulderink F, Cornelisse CJ
The purpose of the study was to investigate the possibilities of flow cytometry (FCM) for the analysis of DNA polyploidy in human heart tissue. Suspensions of single nuclei were prepared with the detergent-trypsin procedure and stained with propidium iodide. A mathematical correction procedure was developed to correct for background and clumping. For diploid model populations of chicken and trout red blood cells this correction reduced artifactual fractions in the FCM DNA profile to less than 0.... Abstract
Cited 21 times since 1986 (0.5 per year) source: EuropePMC
Journal of biomechanics, Volume 19, Issue 10, 1 1 1986, Pages 799-805 Fluid shear as a possible mechanism for platelet diffusivity in flowing blood. Aarts PA, Steendijk P, Sixma JJ, Heethaar RM
Platelet transport theory is based on convection diffusion and describes adequately the influence of wall shear rate, platelet concentration and axial (down stream) position. Until now, the influence of the predominant factors affecting platelet adherence, the hematocrit and the red cell size, was not included in this theory. Their role remained hidden in the platelet diffusivity (Dw), which was assumed to be related to the shear rate (gamma) expressed in s-1 by a power law function Dw = m gamma... Abstract
Cited 550 times since 1984 (13.6 per year) source: EuropePMC
Circulation, Volume 70, Issue 5, 1 1 1984, Pages 812-823 Continuous measurement of left ventricular volume in animals and humans by conductance catheter. Baan J, van der Velde ET, de Bruin HG, Smeenk GJ, Koops J, van Dijk AD, Temmerman D, Senden J, Buis B
An eight-electrode conductance catheter previously developed by us and used to determine stroke volume in dogs was applied in human beings and dogs to measure absolute left ventricular volume quantitatively. For calibration we developed the formula V(t) = (1/alpha)(L2/sigma b)G(t) - Vc, where V(t) is time-varying left ventricular volume, alpha is a dimensionless constant, L is the electrode separation, sigma b is the conductivity of blood obtained by a sampling cuvette, and G(t) is the measured... Abstract
Cited 23 times since 1984 (0.6 per year) source: EuropePMC
Journal of applied physiology: respiratory, environmental and exercise physiology, Volume 56, Issue 4, 1 1 1984, Pages 1053-1059 Breathing pattern during induced bronchoconstriction. Chadha TS, Schneider AW, Birch S, Jenouri G, Sackner MA
The breathing patterns of normal subjects monitored with respiratory inductive plethysmography were investigated after mild increases in respiratory resistance provoked by aerosolized methacholine during natural breathing and while breathing on a mouthpiece to a pneumotachograph. First, during natural breathing, comparisons of inspiratory ventilation (VI), tidal volume (VT), frequency (f), inspiratory time (TI), fractional inspiratory time (TI/TT), and mean inspiratory flow (VT/TI) were made bef... Abstract