Research

Publications

Below you can find a list of our published research.

9543 results

Cited 46 times since 2023 (16.2 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 9, Issue 4, 18 3 2023, Pages 511-522 Very High-Power Ablation for Contiguous Pulmonary Vein Isolation: Results From the Randomized POWER PLUS Trial. O'Neill L, El Haddad M, Berte B, Kobza R, Hilfiker G, Scherr D, Manninger M, Wijnmaalen AP, Trines SA, Wielandts JY, Gillis K, Lycke M, De Becker B, Tavernier R, Le Polain De Waroux JB, Knecht S, Duytschaever M

Background: Very high-power, short-duration (90-W/4-second) ablation for pulmonary vein isolation (PVI) may reduce procedural times. However, shorter applications with higher power may impact lesion quality. Objectives: In this multicenter, randomized controlled trial, the authors compared procedural efficiency, efficacy, and safety of PVI using 90-W/4-second ablation to 35/50-W ablation. Methods: Patients with paroxysmal or persistent atrial fibrillation undergoing first-time PVI were randomize... Abstract

Cited 1 times since 2023 (0.4 per year) source: EuropePMC

The Pediatric infectious disease journal, Volume 42, Issue 4, 18 3 2023, Pages e129 Nowadays a New MIS-C Mimicker: Group A Streptococcal Infections. Elvan-Tuz A, Elvan-Tuz A, Ekemen-Keles Y, Karadag-Oncel E, Yilmaz D, Ozcifci G, Durak F

Abstract

Cited 3 times since 2023 (1.1 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 9, Issue 6, 18 3 2023, Pages 740-748 Head-to-Head Comparison of T1 Mapping and Electroanatomical Voltage Mapping in Patients With Ventricular Arrhythmias. Sramko M, Abdel-Kafi S, Wijnmaalen AP, Tao Q, van der Geest RJ, Lamb HJ, Zeppenfeld K

Background: Electroanatomical voltage mapping (EAVM) has been compared with late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR), which cannot delineate diffuse fibrosis. T1-mapping CMR overcomes the limitations of LGE-CMR, but it has not been directly compared against EAVM. Objectives: This study aims to assess the relationship between left ventricular (LV) endocardial voltage obtained by EAVM and extracellular volume (ECV) obtained by T1 mapping. Methods: The study investiga... Abstract

Cited 14 times since 2023 (4.9 per year) source: EuropePMC

JACC. CardioOncology, Volume 5, Issue 1, 17 3 2023, Pages 102-113 Cardiac Toxicity of Alectinib in Patients With ALK+ Lung Cancer: Outcomes of Cardio-Oncology Follow-Up. Pruis MA, Veerman GDM, Hassing HC, Lanser DAC, Paats MS, van Schaik RHN, Mathijssen RHJ, Manintveld O, Dingemans AC

Background: Anaplastic lymphoma kinase (ALK) translocations in metastatic non-small cell lung cancer (3% to 7%) predict for response to ALK-inhibitors (eg, alectinib, first line), resulting in a 5-year survival rate of ∼60% and median progression-free survival of 34.8 months. Although the overall toxicity rate of alectinib is acceptable, unexplained adverse events, including edema and bradycardia, may indicate potential cardiac toxicity. Objectives: This study's aim was to investigate the c... Abstract

Cited 2 times since 2023 (0.7 per year) source: EuropePMC

Brazilian oral research, Volume 36, 16 3 2023, Pages e140 Evaluation of the predictors of oral health-related quality of life among 3-5-year-old children with dental trauma. Tabakcilar D, Peker K, Yilmaz DO, Kasimoglu Y, Tuna-Ince EB, Gencay K, Seymen F

This study evaluated the influence of socio-demographic, clinical, and parental psychological factors on oral health-related quality of life (OHRQoL) and determined their predictors in preschool-aged children with traumatic dental injury (TDI). The study sample consisted of 324 dyads of children and their parents attending the Clinics of Pediatric Dentistry at Istanbul University. After clinical examination, the Sense of Coherence (SOC), Generalized Self-Efficacy Scale, Early Childhood Oral Heal... Abstract

Cited 2 times since 2023 (0.7 per year) source: EuropePMC

Journal of the peripheral nervous system : JPNS, Volume 28, Issue 1, 14 2 2023, Pages 58-68 The effect of tremor on disability assessment in chronic inflammatory demyelinating polyradiculoneuropathy. van Veen R, Pallada G, Wieske L, Ten Holter SEM, van Rootselaar AF, Verhamme C, de Bie RMA, van Schaik IN, Merkies ISJ, Dijk JM, Eftimov F

Tremor in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is common, often unresponsive to treatment, and may contribute to disability. We aim to investigate whether tremor is associated with disability as measured in daily practice and clinical trials, independent of other impairments. We included 76 CIDP patients in this cross-sectional study. We assessed tremor with the Tremor Research Group essential tremor rating assessment scale (TETRAS) and the Fahn-Tolosa-Marin clinical... Abstract

Cited 6 times since 2023 (2.1 per year) source: EuropePMC

International journal of cancer, Volume 152, Issue 10, 13 2 2023, Pages 2032-2042 Longitudinal associations of adherence to lifestyle recommendations and health-related quality of life in patients with non-muscle invasive bladder cancer. Vidra N, Beeren I, van Zutphen M, Aben KK, Kampman E, Witjes JA, van der Heijden AG, Kiemeney LA, Vrieling A

Although the role of lifestyle in health-related quality of life (HRQoL) outcomes has been increasingly recognized for various types of cancer, evidence in patients with non-muscle invasive bladder cancer (NMIBC) is very limited. We aimed to evaluate the longitudinal association between adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) lifestyle recommendations and HRQoL in patients with NMIBC. This study included 1029 patients with NMIBC recruit... Abstract

Cited 3 times since 2023 (1.1 per year) source: EuropePMC

Annals of vascular surgery, Volume 93, 13 2 2023, Pages 283-290 Evaluation of the Angiosome Concept Using Near-Infrared Fluorescence Imaging with Indocyanine Green. Tange FP, Ferrari BR, van den Hoven P, van Schaik J, Schepers A, van Rijswijk CSP, van der Meer RW, Putter H, Vahrmeijer AL, Hamming JF, van der Vorst JR

Background: The angiosome concept is defined as the anatomical territory of a source artery within all tissue layers. When applying this theory in vascular surgery, direct revascularization (DR) is preferred to achieve increased blood flow toward the targeted angiosome of the foot in patients with lower extremity arterial disease (LEAD). This study evaluates the applicability of the angiosome concept using quantified near-infrared (NIR) fluorescence imaging with indocyanine green (ICG). Methods:... Abstract

Cited 2 times since 2023 (0.7 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 9, 12 2 2023, Pages 1036522 Risk for acquired coronary artery disease in genetic vs. congenital thoracic aortopathy. Dolmaci OB, Ayyildiz T, Poelmann RE, Driessen AHG, Koolbergen DR, Klautz RJM, Lindeman JHN, Grewal N

Objective: Patients with Marfan syndrome (MFS) and patients with a bicuspid aortic valve (BAV) have a significantly increased risk to develop thoracic aortopathy. Both conditions share many pathophysiological mechanisms leading to aortic complications. Bicuspidy is known to have a low risk for acquired coronary artery sclerosis. The aim of this study is to determine the risk of coronary sclerosis in MFS patients. Methods: Marfan syndrome patients with an aortic root dilatation, which were surgic... Abstract

Cited 4 times since 2023 (1.4 per year) source: EuropePMC

European journal of medical research, Volume 28, Issue 1, 11 2 2023, Pages 22 Comparison of telemonitoring combined with intensive patient support with standard care in patients with chronic cardiovascular disease - a randomized clinical trial. Öner A, Dittrich H, Arslan F, Hintz S, Ortak J, Brandewiede B, Mann M, Krockenberger K, Thiéry A, Ziegler A, Schmidt C, CardioCare MV Study Group

Importance: Healthcare concepts for chronic diseases based on tele-monitoring have become increasingly important during COVID-19 pandemic. Objective: To study the effectiveness of a novel integrated care concept (NICC) that combines tele-monitoring with the support of a call centre in addition to guideline therapy for patients with atrial fibrillation, heart failure, or treatment-resistant hypertension. Design: A prospective, parallel-group, open-label, randomized, controlled trial. Setting: Bet... Abstract

Cited 2 times since 2023 (0.7 per year) source: EuropePMC

Veterinary and animal science, Volume 19, 10 2 2023, Pages 100285 Associations of carcass weight and trimming loss with cull dairy cow health observations collected at slaughter. Vlemminx R, Bouwknegt M, Urlings B, van Schaik G

Cull dairy cows account for around 27 percent of total head EU beef and veal production. For the Netherlands specific, even 42 percent (European Commission, 2022). As they are primarily kept to produce milk, red meat production is an additional source of revenue for dairy farmers. Insights in postmortem health observations that are not always visible on the living animal such as heart or liver issues, bruises, adhesions and injuries on the locomotor system, may contain valuable information for f... Abstract

Frontiers in physiology, Volume 13, 10 2 2023, Pages 1127730 Corrigendum: Both caffeine and <i>Capsicum annuum</i> fruit powder lower blood glucose levels and increase brown adipose tissue temperature in healthy adult males. Van Schaik L, Kettle C, Green R, Wundersitz D, Gordon B, Irving HR, Rathner JA

[This corrects the article DOI: 10.3389/fphys.2022.870154.]. Abstract

Cited 1 times since 2023 (0.3 per year) source: EuropePMC

Pediatric emergency care, Volume 39, Issue 2, 9 2 2023, Pages 91-97 The Role of Ultrasound in Pediatric Skull Fractures: Determination of Fracture and Optic Nerve Sheath Diameter Measurements. Şık N, Öztürk A, Yılmaz D, Duman M

Background: The aim of the present study was to determine the accuracy of point-of-care ultrasound (POCUS) for detecting skull fractures and to evaluate sonographic measurements of optic nerve sheath diameter (ONSD) and ONSD/eyeball vertical diameter (EVD) ratios in children with head trauma. Methods: Children who presented with local signs of head trauma and underwent cranial computed tomography (CT) were enrolled. The suspected area was examined by POCUS to identify a skull fracture, and then... Abstract

Cited 11 times since 2023 (3.8 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 9, 9 2 2023, Pages 1032755 Are acute type A aortic dissections atherosclerotic? Grewal N, Dolmaci O, Jansen E, Klautz R, Driessen A, Lindeman J, Poelmann RE

Background: Type A aortic dissections (TAAD) are devastating aortic complications. Patients with Marfan syndrome, a bicuspid aortic valve or a thoracic aortic aneurysm have an increased risk to develop a TAAD. These predisposing conditions are characterized by a histologically thin intimal layer and hardly any atherosclerosis. Little is known about the susceptibility for atherosclerosis in patients with a type A aortic dissection. Objective: We aim to systematically describe atherosclerotic lesi... Abstract

Cited 14 times since 2023 (4.9 per year) source: EuropePMC

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Volume 159, 9 2 2023, Pages 114232 Capecitabine-induced hand-foot syndrome: A pharmacogenetic study beyond DPYD. de With M, van Doorn L, Maasland DC, Mulder TAM, Oomen-de Hoop E, Mostert B, Homs MYV, El Bouazzaoui S, Mathijssen RHJ, van Schaik RHN, Bins S

Aim of the study: Occurrence of hand-foot syndrome (HFS) during capecitabine treatment often results in treatment interruptions (26 %) or treatment discontinuation (17 %), and can severely decrease quality of life. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in genes involved in capecitabine metabolism - other than DPYD - are associated with an increased risk for capecitabine-induced HFS. Methods: Patients treated with capecitabine according to standard of care... Abstract

Cited 4 times since 2023 (1.4 per year) source: EuropePMC

Journal of cardiovascular translational research, Volume 16, Issue 6, 9 2 2023, Pages 1251-1266 Phenotypic and Genetic Factors Associated with Absence of Cardiomyopathy Symptoms in PLN:c.40_42delAGA Carriers. Lopera-Maya EA, Li S, de Brouwer R, Nolte IM, van Breen J, Netherlands A C M/P L N Registry, Lifelines Cohort Study, Jongbloed JDH, Swertz MA, Snieder H, Franke L, Wijmenga C, de Boer RA, Deelen P, van der Zwaag PA, Sanna S

The c.40_42delAGA variant in the phospholamban gene (PLN) has been associated with dilated and arrhythmogenic cardiomyopathy, with up to 70% of carriers experiencing a major cardiac event by age 70. However, there are carriers who remain asymptomatic at older ages. To understand the mechanisms behind this incomplete penetrance, we evaluated potential phenotypic and genetic modifiers in 74 PLN:c.40_42delAGA carriers identified in 36,339 participants of the Lifelines population cohort. Asymptomati... Abstract

Cited 18 times since 2023 (6.3 per year) source: EuropePMC

Vascular pharmacology, Volume 148, 7 1 2023, Pages 107141 The effect of the 2019 ESC/EAS dyslipidaemia guidelines on low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS EuroPath IV project. Laufs U, Catapano AL, De Caterina R, Schiele F, Sionis A, Zaman A, Jukema JW

Aims: To evaluate the effect of the ESC/EAS 2019 dyslipidaemia guidelines on patient management of lipid-lowering therapy in patients with acute coronary syndrome (ACS), through a survey designed to compare post-ACS patient management in 2022 with that in 2018. Methods: Online questionnaires focused on lipid profile and medications were used to gather data from 2650 ACS patients in 6 European countries, treated between March-June 2022 (ACS EuroPath IV survey). These data were compared with data... Abstract

Cited 5 times since 2023 (1.7 per year) source: EuropePMC

Archives of cardiovascular diseases, Volume 116, Issue 2, 7 1 2023, Pages 69-78 Prolongation of the heart rate-corrected QT interval is associated with cardiovascular diseases: Systematic review and meta-analysis. Welten SJGC, Elders PJM, Remmelzwaal S, Doekhie R, Kee KW, Nijpels G, van der Heijden AA, ESCAPE-NET investigators

Background: Conflicting findings have described the association between prolonged heart rate-corrected QT interval (QTc) and cardiovascular disease. Aims: To identify articles investigating the association between QTc and cardiovascular disease morbidity and mortality, and to summarize the available evidence for the general and type 2 diabetes populations. Methods: A systematic search was performed in PubMed and Embase in May 2022 to identify studies that investigated the association between QTc... Abstract

Cited 13 times since 2023 (4.5 per year) source: EuropePMC

Proceedings of the National Academy of Sciences of the United States of America, Volume 120, Issue 2, 6 1 2023, Pages e2121467120 Parental provisioning drives brain size in birds. Griesser M, Drobniak SM, Graber SM, van Schaik CP

Large brains support numerous cognitive adaptations and therefore may appear to be highly beneficial. Nonetheless, the high energetic costs of brain tissue may have prevented the evolution of large brains in many species. This problem may also have a developmental dimension: juveniles, with their immature and therefore poorly performing brains, would face a major energetic hurdle if they were to pay for the construction of their own brain, especially in larger-brained species. Here, we explore t... Abstract

Cited 3 times since 2023 (1 per year) source: EuropePMC

Cellular signalling, Volume 104, 5 1 2023, Pages 110587 Early adipogenesis is repressed through the newly identified FHL2-NFAT5 signaling complex. Clemente-Olivo MP, Hernández-Quiles M, Sparrius R, van der Stoel MM, Janssen V, Habibe JJ, van den Burg J, Jongejan A, Alcaraz-Sobrevals P, van Es R, Vos H, Kalkhoven E, de Vries CJM

The LIM-domain-only protein FHL2 is a modulator of signal transduction and has been shown to direct the differentiation of mesenchymal stem cells towards osteoblast and myocyte phenotypes. We hypothesized that FHL2 may simultaneously interfere with the induction of the adipocyte lineage. Therefore, we investigated the role of FHL2 in adipocyte differentiation. For these studies pre-adipocytes isolated from mouse adipose tissue and the 3T3-L1 (pre)adipocyte cell line were applied. We performed FH... Abstract