9543 results
Vascular,
Volume 31, Issue 6, 16 3 2022, Pages 1051-1060
What we have learned from in-vitro studies of the chimney endovascular technique for treatment of complex abdominal aortic aneurysms: A systematic review.
Meekel JP, Tran BL, van Schaik TG, Donas KP, Taneva GT, Jongkind V, Yeung KK
Background: A considerable number of patients with abdominal aortic aneurysms (AAA) is not eligible for standard endovascular repair. These complex cases require alternative surgical approaches including the readily available chimney graft endovascular aneurysm repair (Ch-EVAR) or sealing (Ch-EVAS). The optimal configuration for Ch-EVAR or Ch-EVAS is important for success but not yet known. Objective: The aim of the present study was to analyze current data of the outcomes of in-vitro chimney gr...
Abstract
Cited 7 times since 2022 (2 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 11, Issue 10, 16 3 2022, Pages e023313
Differences in Characteristics and Outcomes Between Patients With Hypertrophic Cardiomyopathy From Asian and European Centers.
Tjahjadi C, Butcher SC, Zegkos T, Sia CH, Hirasawa K, Kamperidis V, Ngiam JN, Wong RCC, Efthimiadis G, Bax JJ, Delgado V, Ajmone Marsan N
Abstract
Cited 8 times since 2022 (2.3 per year)
source: EuropePMC
Cardiovascular drugs and therapy,
Volume 37, Issue 5, 14 2 2022, Pages 941-953
Implications of ACC/AHA Versus ESC/EAS LDL-C Recommendations for Residual Risk Reduction in ASCVD: A Simulation Study From DA VINCI.
Vallejo-Vaz AJ, Bray S, Villa G, Brandts J, Kiru G, Murphy J, Banach M, De Servi S, Gaita D, Gouni-Berthold I, Kees Hovingh G, Jozwiak JJ, Jukema JW, Gabor Kiss R, Kownator S, Iversen HK, Maher V, Masana L, Parkhomenko A, Peeters A, Clifford P, Raslova K, Siostrzonek P, Romeo S, Tousoulis D, Vlachopoulos C, Vrablik M, Catapano AL, Poulter NR, Ray KK, DA VINCI Study Investigators
Purpose: Low-density lipoprotein cholesterol (LDL-C) recommendations differ between the 2018 American College of Cardiology/American Heart Association (ACC/AHA) and 2019 European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines for patients with atherosclerotic cardiovascular disease (ASCVD) (
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
European urology focus,
Volume 8, Issue 6, 14 2 2022, Pages 1627-1634
T1G1 Bladder Cancer: Prognosis for this Rare Pathological Diagnosis Within the Non-muscle-invasive Bladder Cancer Spectrum.
Beijert IJ, Hentschel AE, Bründl J, Compérat EM, Plass K, Rodríguez O, Subiela Henríquez JD, Hernández V, de la Peña E, Alemany I, Turturica D, Pisano F, Soria F, Čapoun O, Bauerová L, Pešl M, Maxim Bruins H, Runneboom W, Herdegen S, Breyer J, Brisuda A, Calatrava A, Rubio-Briones J, Seles M, Mannweiler S, Bosschieter J, Kusuma VRM, Ashabere D, Huebner N, Cotte J, Mertens LS, Masson-Lecomte A, Liedberg F, Cohen D, Lunelli L, Cussenot O, El Sheikh S, Volanis D, Côté JF, Rouprêt M, Haitel A, Shariat SF, Mostafid AH, Nieuwenhuijzen JA, Zigeuner R, Dominguez-Escrig JL, Hacek J, Zlotta AR, Burger M, Evert M, Hulsbergen-van de Kaa CA, van der Heijden AG, A L M Kiemeney L, Soukup V, Molinaro L, Gontero P, Llorente C, Algaba F, Palou J, N'Dow J, Ribal MJ, van der Kwast TH, Babjuk M, Sylvester RJ, van Rhijn BWG
Background: The pathological existence and clinical consequence of stage T1 grade 1 (T1G1) bladder cancer are the subject of debate. Even though the diagnosis of T1G1 is controversial, several reports have consistently found a prevalence of 2-6% G1 in their T1 series. However, it remains unclear if T1G1 carcinomas have added value as a separate category to predict prognosis within the non-muscle-invasive bladder cancer (NMIBC) spectrum. Objective: To evaluate the prognostic value of T1G1 carcino...
Abstract
Cited 9 times since 2022 (2.6 per year)
source: EuropePMC
Langmuir : the ACS journal of surfaces and colloids,
Volume 38, Issue 20, 13 2 2022, Pages 6281-6294
Discrimination of Receptor-Mediated Endocytosis by Surface-Enhanced Raman Scattering.
Yılmaz D, Culha M
Cellular energy required for the maintenance of cellular life is stored in the form of adenosine triphosphate (ATP). Understanding cellular mechanisms, including ATP-dependent metabolisms, is crucial for disease diagnosis and treatment, including drug development and investigation of new therapeutic systems. As an ATP-dependent metabolism, endocytosis plays a key role not only in the internalization of molecules but also in processes including cell growth, differentiation, and signaling. To unde...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985),
Volume 133, Issue 1, 12 2 2022, Pages 20-26
Graded lower body negative pressure induces intraventricular negative pressures and incremental diastolic suction: a pressure-volume study in a porcine model.
Berboth L, Zirngast B, Manninger M, Steendijk P, Tschöpe C, Scherr D, Hinghofer-Szalkay HG, Goswami N, Petersen LG, Mächler H, Alogna A
Lower body negative pressure (LBNP) is a tool to study compensatory mechanisms to central hypovolemia for decades. However, the underlying hemodynamic mechanisms were mostly assessed noninvasively and remain unclear. We hypothesized that incremental LBNP reduces diastolic filling and thereby affects left ventricular (LV) diastolic suction (DS). Here, we investigated the impact of graded LBNP at three different levels of seal as well as during β-adrenergic stimulation by invasive pressure-volume...
Abstract
Cited 500 times since 2022 (141.7 per year)
source: EuropePMC
Nature genetics,
Volume 54, Issue 5, 12 2 2022, Pages 560-572
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, Robertson NR, Rayner NW, Loh M, Kim BJ, Chiou J, Miguel-Escalada I, Della Briotta Parolo P, Lin K, Bragg F, Preuss MH, Takeuchi F, Nano J, Guo X, Lamri A, Nakatochi M, Scott RA, Lee JJ, Huerta-Chagoya A, Graff M, Chai JF, Parra EJ, Yao J, Bielak LF, Tabara Y, Hai Y, Steinthorsdottir V, Cook JP, Kals M, Grarup N, Schmidt EM, Pan I, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Long J, Sun M, Tong L, Chen WM, Ahmad M, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Lecoeur C, Prins BP, Nicolas A, Yanek LR, Chen G, Jensen RA, Tajuddin S, Kabagambe EK, An P, Xiang AH, Choi HS, Cade BE, Tan J, Flanagan J, Abaitua F, Adair LS, Adeyemo A, Aguilar-Salinas CA, Akiyama M, Anand SS, Bertoni A, Bian Z, Bork-Jensen J, Brandslund I, Brody JA, Brummett CM, Buchanan TA, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chu
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis of Trans-Ethnic association studies (DIAMANTE) Consortium. Multi-ancestry GWAS meta-analysis identified 237 loci attaining stringent genome-wide significance (P 50% posterior probability. This improved fine-mapping enabled systematic assessment of candidate causal ge...
Abstract
Cited 3 times since 2022 (0.8 per year)
source: EuropePMC
Royal Society open science,
Volume 9, Issue 5, 11 2 2022, Pages 220011
Martingales and the fixation time of evolutionary graphs with arbitrary dimensionality.
Monk T, van Schaik A
Evolutionary graph theory (EGT) investigates the Moran birth-death process constrained by graphs. Its two principal goals are to find the fixation probability and time for some initial population of mutants on the graph. The fixation probability of graphs has received considerable attention. Less is known about the distribution of fixation time. We derive clean, exact expressions for the full conditional characteristic functions (CCFs) of a close proxy to fixation and extinction times. That prox...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 30, Issue 1, 10 2 2022, Pages 83-84
<sup>18</sup>F-FDG PET/CT for the diagnosis of aortic inflammation in COVID-19.
van der Bijl P, Stassen J, Bax JJ
Abstract
Cited 4 times since 2022 (1.1 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 9, 10 2 2022, Pages 870459
Atrioventricular Block Necessitating Chronic Ventricular Pacing After Tricuspid Valve Surgery in Patients With a Systemic Right Ventricle: Long-Term Follow-Up.
Nederend M, Jongbloed MRM, Kiès P, Vliegen HW, Bouma BJ, Regeer MV, Koolbergen DR, Hazekamp MG, Schalij MJ, Egorova AD
Background: Patients with transposition of the great arteries (TGA) after an atrial switch or congenitally corrected TGA (ccTGA) are prone to systemic right ventricular (sRV) failure. Tricuspid valve (TV) regurgitation aggravates sRV dysfunction. Timely TV surgery stabilizes sRV function, yet the development of atrioventricular (AV)-conduction disturbances in the course of sRV failure can contribute to sRV dysfunction through pacing-induced dyssynchrony. This study aims to explore the incidence,...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 38, Issue 7, 9 2 2022, Pages 1639-1650
Atherosclerotic plaque characteristics on quantitative coronary computed tomography angiography associated with ischemia on positron emission tomography in diabetic patients.
Kamperidis V, de Graaf MA, Uusitalo V, Saraste A, Kuneman JH, van den Hoogen IJ, Knuuti J, Bax JJ
Patients with diabetes mellitus (DM) may show diffuse coronary artery atherosclerosis on coronary computed tomography angiography (CTA). The present study aimed at quantification of atherosclerotic plaque with CTA and its association with myocardial ischemia on positron emission tomography (PET) in DM patients. Of 922 symptomatic outpatients without previously known coronary artery disease who underwent CTA, 115 with DM (mean age 65 ± 8 years, 58% male) who had coronary atherosclerosis and under...
Abstract
Cancers,
Volume 14, Issue 9, 8 2 2022, Pages 2329
Impaired Global Longitudinal Strain Is Associated with Cardiovascular Events in Hodgkin Lymphoma Survivors.
Polomski EAS, Heemelaar JC, Krol ADG, Louwerens M, Beeres SLMA, Holman ER, Jukema JW, Schalij MJ, Antoni ML
Background: Treatment with thoracic irradiation for classic Hodgkin lymphoma (CHL) leads to improved survival but also increases the risk of cardiovascular events. Left ventricular (LV) dysfunction is usually assessed by echocardiographic left ventricular ejection fraction (LVEF), whereas global longitudinal strain (GLS) can detect early subclinical LV dysfunction. The purpose of this study was to evaluate if conventional echocardiographic parameters and GLS are associated with cardiovascular ev...
Abstract
Cited 12 times since 2022 (3.4 per year)
source: EuropePMC
American heart journal,
Volume 250, 7 1 2022, Pages 45-56
COMPARE LAAO: Rationale and design of the randomized controlled trial "COMPARing Effectiveness and safety of Left Atrial Appendage Occlusion to standard of care for atrial fibrillation patients at high stroke risk and ineligible to use oral anticoagulation therapy".
Huijboom M, Maarse M, Aarnink E, van Dijk V, Swaans M, van der Heijden J, IJsselmuiden S, Folkeringa R, Blaauw Y, Elvan A, Stevenhagen J, Vlachojannis G, van der Voort P, Westra S, Chaldoupi M, Khan M, de Groot J, van der Kley F, van Mieghem N, van Dijk E, Dijkgraaf M, Tijssen J, Boersma L
Background: Left atrial appendage occlusion (LAAO) provides an alternative to oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation (AF). In patients with a long-term or permanent contraindication for OAC randomized controlled trial (RCT) data is lacking. Study objectives: To assess the efficacy and safety of LAAO in AF patients who are ineligible to use OAC. The co-primary efficacy endpoint is (1) time to first occurrence of stroke (ischemic, hemorrhagic, or unde...
Abstract
Cited 3 times since 2022 (0.8 per year)
source: EuropePMC
Journal of cardiothoracic surgery,
Volume 17, Issue 1, 7 1 2022, Pages 108
Accuracy of point-of-care coagulation testing during cardiopulmonary bypass in a patient post COVID-19 infection.
Grewal N, Yousef D, Palmen M, Klautz R, Eikenboom J, Wink J
Introduction: Extracorporeal circulation (ECC) in cardiac surgery is performed under systemic heparinization. Adequacy of heparin therapy and anticoagulation during ECC is assessed by activated clotting time (ACT), although there are concerns regarding the reliability of this measure. The ACT can be affected by factors other than heparin anticoagulation. A novel factor that should be considered is the influence of a COVID-19 infection. More than half of the hospitalized COVID-19 patients develop...
Abstract
Cited 11 times since 2022 (3.1 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 9, 6 1 2022, Pages 883873
Performance of a HeartLogic<sup>TM</sup> Based Care Path in the Management of a Real-World Chronic Heart Failure Population.
Feijen M, Egorova AD, Treskes RW, Mertens BJA, Jukema JW, Schalij MJ, Beeres SLMA
Aim: Early detection of impending fluid retention and timely adjustment of (medical) therapy can prevent heart failure related hospitalizations. The multisensory cardiac implantable electronic device (CIED) based algorithm HeartLogicTM aims to alert in case of impending fluid retention. The aim of the current analysis is to evaluate the performance of the HeartLogicTM guided heart failure care path in a real-world heart failure population and to investigate whether the height of the index and th...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 16, 6 1 2022, Pages 821157
Real-Time Event-Based Unsupervised Feature Consolidation and Tracking for Space Situational Awareness.
Ralph N, Joubert D, Jolley A, Afshar S, Tothill N, van Schaik A, Cohen G
Earth orbit is a limited natural resource that hosts a vast range of vital space-based systems that support the international community's national, commercial and defence interests. This resource is rapidly becoming depleted with over-crowding in high demand orbital slots and a growing presence of space debris. We propose the Fast Iterative Extraction of Salient targets for Tracking Asynchronously (FIESTA) algorithm as a robust, real-time and reactive approach to optical Space Situational A...
Abstract
Cited 10 times since 2022 (2.8 per year)
source: EuropePMC
PLoS biology,
Volume 20, Issue 5, 6 1 2022, Pages e3001630
The function and evolution of child-directed communication.
Schick J, Fryns C, Wegdell F, Laporte M, Zuberbühler K, van Schaik CP, Townsend SW, Stoll S
Humans communicate with small children in unusual and highly conspicuous ways (child-directed communication (CDC)), which enhance social bonding and facilitate language acquisition. CDC-like inputs are also reported for some vocally learning animals, suggesting similar functions in facilitating communicative competence. However, adult great apes, our closest living relatives, rarely signal to their infants, implicating communication surrounding the infant as the main input for infant great apes...
Abstract
Cited 22 times since 2022 (6.2 per year)
source: EuropePMC
Nutrients,
Volume 14, Issue 9, 6 1 2022, Pages 1945
Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients.
de Graaf MCG, Spooren CEGM, Hendrix EMB, Hesselink MAM, Feskens EJM, Smolinska A, Keszthelyi D, Pierik MJ, Mujagic Z, Jonkers DMAE
Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) share common culprit foods and potential pathophysiological factors. However, how diet may contribute to disease course and whether this differs between both entities is unclear. We therefore investigated the association of dietary indices with intestinal inflammation and gastrointestinal symptoms in both IBD and IBS patients. Food frequency questionnaires from 238 IBD, 261 IBS and 195 healthy controls (HC) were available to cal...
Abstract
Cited 7 times since 2022 (2 per year)
source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985),
Volume 132, Issue 6, 5 1 2022, Pages 1560-1568
Cerebral hemodynamics during sustained intraoperative hypotension.
Kho E, Sperna Weiland NH, Vlaar APJ, Veelo DP, van der Ster BJP, Corsmit OT, Koolbergen DR, Dilai J, Immink RV
Static cerebral autoregulation (CA) maintains cerebral blood flow (CBF) relatively constant above a mean arterial blood pressure (BPmean) of 60-65 mmHg. Below this lower limit of CA (LLCA), CBF declines along with BPmean. Data are lacking in describing how CA reacts to sustained hypotension since hypotension is usually avoided. In this study, we took advantage of a procedure requiring sustained hypotension. We assessed static CA for LLCA determination, and a more continuous CA, which counters sh...
Abstract
Cited 40 times since 2022 (11.3 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 112, Issue 1, 4 1 2022, Pages 62-68
Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.
de With M, Knikman J, de Man FM, Lunenburg CATC, Henricks LM, van Kuilenburg ABP, Maring JG, van Staveren MC, de Vries N, Rosing H, Beijnen JH, Pluim D, Modak A, Imholz ALT, van Schaik RHN, Schellens JHM, Gelderblom H, Cats A, Guchelaar HJ, Mathijssen RHJ, Swen JJ, Meulendijks D
In clinical practice, 25-30% of the patients treated with fluoropyrimidines experience severe fluoropyrimidine-related toxicity. Extensively clinically validated DPYD genotyping tests are available to identify patients at risk of severe toxicity due to decreased activity of dihydropyrimidine dehydrogenase (DPD), the rate limiting enzyme in fluoropyrimidine metabolism. In April 2020, the European Medicines Agency recommended that, as an alternative for DPYD genotype-based testing for DPD deficien...
Abstract
