9543 results
Cited 10 times since 2020 (1.9 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 98, Issue 4, 13 2 2020, Pages 691-700
Clinical relevance of adding intravascular ultrasound to coronary angiography for the diagnosis of extrinsic left main coronary artery compression by a pulmonary artery aneurysm in pulmonary hypertension.
Velázquez Martín M, Montero Cabezas JM, Huertas S, Nuche J, Albarrán A, Delgado JF, Alonso S, Sarnago F, Arribas F, Escribano Subias P
Objectives: We sought to assess the clinical value of adding intravascular ultrasound (IVUS) evaluation to coronary angiography (CA) to guide extrinsic left main coronary artery (LMCA) compression diagnosis and treatment in pulmonary hypertension (PH). Background: LMCA compression due to a pulmonary artery aneurysm (PAA) is a severe complication of PH. Although guidelines encourage the use of IVUS for LMCA disease evaluation, it has hardly been used in this scenario. Methods: We analyzed morbimo...
Abstract
Cited 12 times since 2020 (2.3 per year)
source: EuropePMC
Obesity facts,
Volume 13, Issue 4, 11 2 2020, Pages 361-370
Experiences with Glucagon-Like Peptide-1 Receptor Agonist in Children with Acquired Hypothalamic Obesity.
van Schaik J, Begijn DGA, van Iersel L, Vergeer Y, Hoving EW, Peeters B, van Santen HM
Objective: Hypothalamic obesity (HO) in children after treatment for a tumor in the suprasellar region has severe implications. Previous studies have shown various effects of glucagon-like peptide-1 (GLP-1) receptor agonist in acquired HO, but in adults only. We present our experience of GLP-1 receptor agonist (exenatide) treatment during a 1-year period on body mass index (BMI) in children with acquired HO. Patients and methods: Children with severe weight gain after treatment for suprasellar t...
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Langenbeck's archives of surgery,
Volume 405, Issue 6, 11 2 2020, Pages 851-859
Outcomes of parathyroidectomy versus calcimimetics for secondary hyperparathyroidism and kidney transplantation: a propensity-matched analysis.
Koh EY, van der Plas WY, Dulfer RR, Pol RA, Kruijff S, Rotmans JI, Appelman-Dijkstra N, Schepers A, de Borst MH, Hoorn EJ, van Ginhoven TM, Nieveen van Dijkum EJM, Vogt L, Engelsman AF, Dutch Hyperparathyroidism Study Group
Purpose: Calcimimetics are currently indicated for severe secondary hyperparathyroidism (SHPT). However, the role of parathyroidectomy (PTX) for these patients is still under debate, and its impact on subsequent kidney transplantation (KTX) is unclear. In this study, we compare the outcomes of kidney transplantation after PTX or medical treatment. Methods: Patients who underwent KTX and had SHPT were analyzed retrospectively. Two groups were selected (patients who had either PTX or calcimimetics...
Abstract
Cited 6 times since 2020 (1.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 36, Issue 12, 10 2 2020, Pages 2357-2364
Per-lesion versus per-patient analysis of coronary artery disease in predicting the development of obstructive lesions: the Progression of AtheRosclerotic PlAque DetermIned by Computed TmoGraphic Angiography Imaging (PARADIGM) study.
Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
To determine whether the assessment of individual plaques is superior in predicting the progression to obstructive coronary artery disease (CAD) on serial coronary computed tomography angiography (CCTA) than per-patient assessment. From a multinational registry of 2252 patients who underwent serial CCTA at a ≥ 2-year inter-scan interval, patients with only non-obstructive lesions at baseline were enrolled. CCTA was quantitatively analyzed at both the per-patient and per-lesion level. Models pred...
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 60, Issue 4, 10 2 2020, Pages 632-633
Imaging Assessment of Carotid Artery Stenosis Varies in Clinical Practice.
Brouwers JJWM, Versluijs Y, van Walderveen MAA, Hamming JF, Schepers A
Abstract
Cited 10 times since 2020 (1.9 per year)
source: EuropePMC
European journal of medical genetics,
Volume 63, Issue 11, 7 1 2020, Pages 104032
Glutaric aciduria type 1: Genetic and phenotypic spectrum in 53 patients.
Gürbüz BB, Yılmaz DY, Coşkun T, Tokatlı A, Dursun A, Sivri HS
Introduction: Glutaric aciduria type 1 (GA1) is a rare and inherited autosomal-recessive metabolic disorder that occurs in the deficiency of glutaryl-co-enzyme A dehydrogenase (GCDH) enzyme encoded by GCDH gene. In this study, we aim to retrospectively investigate the clinical, biochemical, and neuroradiological parameters and examine the spectrum of GCDH gene variants in Turkish patients with glutaric aciduria type 1. Methods: This is a descriptive cross-sectional study. The study was conducted...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
International journal of environmental research and public health,
Volume 17, Issue 16, 7 1 2020, Pages E5707
Automatic Process Comparison for Subpopulations: Application in Cancer Care.
Marazza F, Bukhsh FA, Geerdink J, Vijlbrief O, Pathak S, Keulen MV, Seifert C
Processes in organisations, such as hospitals, may deviate from the intended standard processes, due to unforeseeable events and the complexity of the organisation. For hospitals, the knowledge of actual patient streams for patient populations (e.g., severe or non-severe cases) is important for quality control and improvement. Process discovery from event data in electronic health records can shed light on the patient flows, but their comparison for different populations is cumbersome and time-c...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Clinical case reports,
Volume 8, Issue 11, 6 1 2020, Pages 2320-2321
The constrictive consequences of pericardial calcifications.
Egorova AD, Schalij MJ, Kiès P
A 53-year-old man presented with symptomatic severe pulmonary valve regurgitation. He underwent a diagnostic catheterization. A heavily calcified pericardium and the pressure tracings illustrate typical features of constrictive pericarditis physiology, including the "square root sign." This condition is important to recognize given the progressive nature and poor prognosis if untreated.
Abstract
Cited 102 times since 2020 (19.2 per year)
source: EuropePMC
Cancer immunology research,
Volume 8, Issue 10, 5 1 2020, Pages 1311-1321
CD39 Identifies the CD4<sup>+</sup> Tumor-Specific T-cell Population in Human Cancer.
Kortekaas KE, Santegoets SJ, Sturm G, Ehsan I, van Egmond SL, Finotello F, Trajanoski Z, Welters MJP, van Poelgeest MIE, van der Burg SH
The accumulation of tumor-specific CD4+ and CD8+ effector T cells is key to an effective antitumor response. Locally, CD4+ T cells promote the recruitment and effector function of tumor-specific CD8+ T cells and activate innate killer cells in the tumor. Here, we show that tumor-specific CD4+ T cells were predominantly present in the CD39+ subset of tumor-infiltrating lymphocytes (TIL). The CD39+ CD4+ and CD8+ TILs were detected in three different tumor types, and displayed an activated (PD-1+,...
Abstract
Cited 22 times since 2020 (4.1 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 25, Issue 3, 5 1 2020, Pages 230-237
Placebo effect in chronic inflammatory demyelinating polyneuropathy: The PATH study and a systematic review.
Lewis RA, Cornblath DR, Hartung HP, Sobue G, Lawo JP, Mielke O, Durn BL, Bril V, Merkies ISJ, Bassett P, Cleasby A, van Schaik IN, PATH study group
The Polyneuropathy And Treatment with Hizentra (PATH) study required subjects with chronic inflammatory demyelinating polyneuropathy (CIDP) to show dependency on immunoglobulin G (IgG) and then be restabilized on IgG before being randomized to placebo or one of two doses of subcutaneous immunoglobulin (SCIG). Nineteen of the 51 subjects (37%) randomized to placebo did not relapse over the next 24 weeks. This article explores the reasons for this effect. A post-hoc analysis of the PATH placebo gr...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
BMC medical education,
Volume 20, Issue 1, 5 1 2020, Pages 250
Refuting misconceptions in medical physiology.
Versteeg M, van Loon MH, Wijnen-Meijer M, Steendijk P
Background: In medical physiology, educators and students face a serious challenge termed misconceptions. Misconceptions are incorrect ideas that do not match current scientific views. Accordingly, they have shown to hamper teaching and learning of physiological concepts. Conceptual Change Theory forms the basis of new teaching and learning practices that may alleviate misconceptions and facilitate critical thinking skills that are essential in becoming knowledgeable, self-regulated health profe...
Abstract
Cited 23 times since 2020 (4.3 per year)
source: EuropePMC
Molecular ecology resources,
Volume 20, Issue 6, 4 1 2020, Pages 1706-1722
A GT-seq panel for walleye (Sander vitreus) provides important insights for efficient development and implementation of amplicon panels in non-model organisms.
Bootsma ML, Gruenthal KM, McKinney GJ, Simmons L, Miller L, Sass GG, Larson WA
Targeted amplicon sequencing methods, such as genotyping-in-thousands by sequencing (GT-seq), facilitate rapid, accurate, and cost-effective analysis of hundreds of genetic loci in thousands of individuals. Development of GT-seq panels is nontrivial, but studies describing trade-offs associated with different steps of GT-seq panel development are rare. Here, we construct a dual-purpose GT-seq panel for walleye (Sander vitreus), discuss trade-offs associated with different development and genotyp...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 5, 4 1 2020, Pages 2343-2345
Hybrid Positron emission tomography/magnetic resonance imaging in viability assessment.
Bax JJ, Ng ACT, Delgado V
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue Suppl 1, 1 1 2020, Pages 115-121
The role of long-term mechanical circulatory support in patients with advanced heart failure.
Felix SEA, de Jonge N, Caliskan K, Birim O, Damman K, Kuijpers M, Tops LF, Palmen M, Ramjankhan FZ
In patients with end-stage heart failure, advanced therapies such as heart transplantation and long-term mechanical circulatory support (MCS) with a left ventricular assist device (LVAD) have to be considered. LVADs can be implanted as a bridge to transplantation or as an alternative to heart transplantation: destination therapy. In the Netherlands, long-term LVAD therapy is gaining importance as a result of increased prevalence of heart failure together with a low number of heart transplantatio...
Abstract
Cited 46 times since 2020 (8.7 per year)
source: EuropePMC
Lab on a chip,
Volume 20, Issue 17, 1 1 2020, Pages 3132-3143
Multiplexed blood-brain barrier organ-on-chip.
Zakharova M, Palma do Carmo MA, van der Helm MW, Le-The H, de Graaf MNS, Orlova V, van den Berg A, van der Meer AD, Broersen K, Segerink LI
Organ-on-chip devices are intensively studied in academia and industry due to their high potential in pharmaceutical and biomedical applications. However, most of the existing organ-on-chip models focus on proof of concept of individual functional units without the possibility of testing multiple experimental stimuli in parallel. Here we developed a polydimethylsiloxane (PDMS) multiplexed chip with eight parallel channels branching from a common access port through which all eight channels can b...
Abstract
Cited 9 times since 2020 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 828-832
EACVI survey on the evaluation of infective endocarditis.
Holte E, Dweck MR, Marsan NA, D'Andrea A, Manka R, Stankovic I, Haugaa KH
Aims: To evaluate the diagnosis and imaging of patients with suspected endocarditis and the management in routine clinical practice across Europe, the EACVI Scientific Initiatives Committee performed a survey across European centres. In particular, the routine use of echocardiography, advanced imaging modalities and multidisciplinary team was explored. Methods and results: A total of 100 European Echocardiography Laboratories from 29 different countries responded to the survey, which consisted o...
Abstract
Cited 8 times since 2020 (1.5 per year)
source: EuropePMC
European journal of emergency medicine : official journal of the European Society for Emergency Medicine,
Volume 27, Issue 4, 1 1 2020, Pages 243-244
The new era of chest pain evaluation in the Netherlands.
Backus BE, Tolsma RT, Boogers MJ
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 116, Issue 10, 1 1 2020, Pages e115-e117
Gender balance at the heart of science.
Small HY, Timoteo AT, Buchanan GL, Gimelli A, Jurcut R, Marsan NA, Schüpke S, Zuhlke L
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 30, 1 1 2020, Pages 2828-2829
EHRA 2020 during COVID-19 days.
Burri H, Zeppenfeld K, Heidbuchel H
Abstract
Cited 13 times since 2020 (2.4 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 937-938
Echocardiography-computed tomography fusion imaging for guidance of transcatheter tricuspid valve annuloplasty.
Fortuni F, Marques AI, Bax JJ, Ajmone Marsan N, Delgado V
Abstract
