Research

Publications

Below you can find a list of our published research.

9543 results

Cited 5 times since 2020 (0.9 per year) source: EuropePMC

Journal of neurology, Volume 268, Issue 1, 31 5 2020, Pages 133-139 Presentation outside office hours does not negatively influence treatment times for reperfusion therapy for acute ischemic stroke. Groot AE, de Bruin H, Nguyen TTM, Kappelhof M, de Beer F, Visser MC, Zwetsloot CP, Halkes PHA, de Kruijk J, van der Meulen WDM, van der Ree TC, Kwa VIH, van Schaik SM, Hani L, van den Berg R, Sprengers MES, Roosendaal SD, Emmer BJ, Nederkoorn PJ, Majoie CBLM, Roos YBWEM, Coutinho JM

Background: Treatment outside office hours has been associated with increased workflow times for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Limited data suggest that this "off-hours effect" also exists for endovascular treatment (EVT). We investigated this phenomenon in a well-organized acute stroke care region in the Netherlands. Methods: Retrospective, observational cohort study of consecutive patients with AIS who received reperfusion therapy in the Greater Amste... Abstract

Cited 8 times since 2020 (1.5 per year) source: EuropePMC

Diabetologia, Volume 63, Issue 11, 31 5 2020, Pages 2452-2461 A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective. Emamipour S, van der Heijden AAWA, Nijpels G, Elders P, Beulens JWJ, Postma MJ, van Boven JFM, Feenstra TL

Aims/hypothesis: In this study we examined the cost-effectiveness of three different screening strategies for diabetic retinopathy: using a personalised adaptive model, annual screening (fixed intervals), and the current Dutch guideline (stratified based on previous retinopathy grade). Methods: For each individual, optimal diabetic retinopathy screening intervals were determined, using a validated risk prediction model. Observational data (1998-2017) from the Hoorn Diabetes Care System cohort of... Abstract

Cited 19 times since 2020 (3.6 per year) source: EuropePMC

Journal of dairy science, Volume 103, Issue 10, 31 5 2020, Pages 9446-9463 Quantification of risk factors for bovine viral diarrhea virus in cattle herds: A systematic search and meta-analysis of observational studies. van Roon AM, Mercat M, van Schaik G, Nielen M, Graham DA, More SJ, Guelbenzu-Gonzalo M, Fourichon C, Madouasse A, Santman-Berends IMGA

Bovine viral diarrhea virus (BVDV) is endemic in many parts of the world, and multiple countries have implemented surveillance activities for disease control or eradication. In such control programs, the disease-free status can be compromised by factors that pose risks for introduction or persistence of the virus. The aim of the present study was to gain a comprehensive overview of possible risk factors for BVDV infection in cattle herds in Europe and to assess their importance. Papers that cons... Abstract

Cited 4 times since 2020 (0.8 per year) source: EuropePMC

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Volume 375, Issue 1805, 29 5 2020, Pages 20190423 Spontaneous (minimal) ritual in non-human great apes? Tennie C, van Schaik CP

The potential for rituals in non-human great apes (apes) is an understudied topic. We derive a minimal definition of ritual and then examine the currently available evidence for it in untrained and non-enculturated apes. First, we examine whether such apes show evidence for the two main components of our minimal definition of ritual: symbolism and copying. Second, we examine if there are actual cases already identifiable today that may fit all aspects of our minimal definition of ritual-or wheth... Abstract

Cited 25 times since 2020 (4.7 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 6, Issue 9, 29 5 2020, Pages 1103-1114 Prevalence and Prognostic Impact of Pathogenic Variants in Patients With Dilated Cardiomyopathy Referred for Ventricular Tachycardia Ablation. Ebert M, Wijnmaalen AP, de Riva M, Trines SA, Androulakis AFA, Glashan CA, Schalij MJ, Peter van Tintelen J, Jongbloed JDH, Zeppenfeld K

Objectives: This study aimed to assess the frequency of (likely) pathogenic variants (LP/Pv) among dilated cardiomyopathy (DCM) ventricular tachycardia (VT) patients referred for CA and their impact on procedural outcome and long-term prognosis. Background: The prevalence of genetic variants associated with monomorphic VT among DCM is unknown. Methods: Ninety-eight consecutive patients (age 56 ± 15 years; 84% men, left ventricular ejection fraction [LVEF] 39 ± 12%) referred for DCM-VT ablation w... Abstract

Cited 7 times since 2020 (1.3 per year) source: EuropePMC

Pediatric nephrology (Berlin, Germany), Volume 36, Issue 2, 29 5 2020, Pages 417-423 Evaluation of non-infectious complications of peritoneal dialysis in children: a multicenter study. Aksoy GK, Ekim M, Bakkaloğlu SA, Coşkun S, Delibaş A, Conkar S, Yılmaz D, Kara A, Saygılı SK, Büyükkaragöz B, Yıldırım ZY, Çomak E, Gürgöze MK, Sever L, Noyan A, Bayazıt AK, Düşünsel R

Background: Peritoneal dialysis (PD) is the most common kidney replacement therapy in children. Complications associated with PD affect treatment success and sustainability. The aim of this study was to investigate the frequency of PD-related non-infectious complications and the predisposing factors. Methods: Retrospective data from 11 centers in Turkey between 1998 and 2018 was collected. Non-infectious complications of peritoneal dialysis (NICPD), except metabolic ones, in pediatric patients w... Abstract

Cited 19 times since 2020 (3.6 per year) source: EuropePMC

EJNMMI research, Volume 10, Issue 1, 28 4 2020, Pages 87 Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer. Baart VM, Houvast RD, de Geus-Oei LF, Quax PHA, Kuppen PJK, Vahrmeijer AL, Sier CFM

The urokinase plasminogen activator receptor (uPAR) plays a multifaceted role in almost any process where migration of cells and tissue-remodeling is involved such as inflammation, but also in diseases as arthritis and cancer. Normally, uPAR is absent in healthy tissues. By its carefully orchestrated interaction with the protease urokinase plasminogen activator and its inhibitor (plasminogen activator inhibitor-1), uPAR localizes a cascade of proteolytic activities, enabling (patho)physiologic c... Abstract

Cited 12 times since 2020 (2.3 per year) source: EuropePMC

The American journal of cardiology, Volume 133, 28 4 2020, Pages 39-47 Five-Year Outcomes and Prognostic Value of Feature-Tracking Cardiovascular Magnetic Resonance in Patients Receiving Early Prereperfusion Metoprolol in Acute Myocardial Infarction. Podlesnikar T, Pizarro G, Fernández-Jiménez R, Montero-Cabezas JM, Sánchez-González J, Bucciarelli-Ducci C, Ajmone Marsan N, Fras Z, Bax JJ, Fuster V, Ibáñez B, Delgado V

The aim of the present study was to investigate the long-term impact of early intravenous metoprolol in ST-segment elevation myocardial infarction (STEMI) patients in terms of left ventricular (LV) strain with feature-tracking cardiovascular magnetic resonance (CMR) and its association with prognosis. A total of 270 patients with first anterior STEMI enrolled in the randomized METOCARD-CNIC clinical trial, assigned to receive up to 15 mg intravenous metoprolol before primary percutaneous coronar... Abstract

Cited 31 times since 2020 (5.8 per year) source: EuropePMC

European journal of preventive cardiology, Volume 28, Issue 1, 27 4 2020, Pages 33-43 Intensity of statin treatment after acute coronary syndrome, residual risk, and its modification by alirocumab: insights from the ODYSSEY OUTCOMES trial. Diaz R, Li QH, Bhatt DL, Bittner VA, Baccara-Dinet MT, Goodman SG, Jukema JW, Kimura T, Parkhomenko A, Pordy R, Reiner Ž, Roe MT, Szarek M, Tse HF, White HD, Zahger D, Zeiher AM, Schwartz GG, Steg PG, ODYSSEY OUTCOMES Committees and Investigators

Aims: Statins are pivotal to the secondary prevention of major adverse cardiovascular events, but some patients are statin-intolerant. We examined the effects of the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor alirocumab on the risk of major adverse cardiovascular events according to the intensity of background statin treatment. Methods and results: The ODYSSEY OUTCOMES trial compared alirocumab with placebo in 18,924 patients with acute coronary syndrome and dyslipidaemia de... Abstract

Cited 11 times since 2020 (2.1 per year) source: EuropePMC

BioMed research international, Volume 2020, 27 4 2020, Pages 8748934 Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial. Sbrana S, Campolo J, Clemente A, Bastiani L, Cecchettini A, Ceccherini E, Caselli C, Neglia D, Parodi O, Chiappino D, Smit JM, Scholte AJ, Pelosi G, Rocchiccioli S

Background and aims: Atherosclerosis is an inflammatory disease with long-lasting activation of innate immunity and monocytes are the main blood cellular effectors. We aimed to investigate monocyte phenotype (subset fraction and marker expression) at different stages of coronary atherosclerosis in stable coronary artery disease (CAD) patients. Methods: 73 patients with chronic coronary syndrome were evaluated by CT coronary angiography (CTCA) and classified by maximal diameter stenosis of major... Abstract

Cited 8 times since 2020 (1.5 per year) source: EuropePMC

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 60, Issue 4, 27 4 2020, Pages 502-508 A Composite Measure for Quality of Care in Patients with Symptomatic Carotid Stenosis Using Textbook Outcome. Kuhrij LS, Karthaus EG, Vahl AC, Willems MCM, Elshof JW, de Borst GJ, Dutch Audit for Carotid Interventions (DACI) Collaborators

Objective: Composite measures may better objectify hospital performance than individual outcome measures (IOM). Textbook outcome (TO) is an outcome measure achieved for an individual patient when all undesirable outcomes are absent. The aim of this study was to assess TO as an additional outcome measure to evaluate quality of care in symptomatic patients treated by carotid endarterectomy (CEA). Methods: All symptomatic patients treated by CEA in 2018, registered in the Dutch Audit for Carotid In... Abstract

Cited 34 times since 2020 (6.4 per year) source: EuropePMC

British journal of clinical pharmacology, Volume 87, Issue 3, 26 4 2020, Pages 1069-1081 Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder. Kloosterboer SM, de Winter BCM, Reichart CG, Kouijzer MEJ, de Kroon MMJ, van Daalen E, Ester WA, Rieken R, Dieleman GC, van Altena D, Bartelds B, van Schaik RHN, Nasserinejad K, Hillegers MHJ, van Gelder T, Dierckx B, Koch BCP

Aim: Risperidone is the most commonly prescribed antipsychotic drug to children and adolescents worldwide, but it is associated with serious side effects, including weight gain. This study assessed the relationship of risperidone and 9-hydroxyrisperidone trough concentrations, maximum concentrations and 24-hour area under the curves (AUCs) with body mass index (BMI) z-scores in children and adolescents with autism spectrum disorder (ASD) and behavioural problems. Secondary outcomes were metaboli... Abstract

Cited 10 times since 2020 (1.9 per year) source: EuropePMC

Journal of the American Heart Association, Volume 9, Issue 15, 25 4 2020, Pages e016990 Prespecified Risk Criteria Facilitate Adequate Discharge and Long-Term Outcomes After Transfemoral Transcatheter Aortic Valve Implantation. Spence MS, Baan J, Iacovelli F, Martinelli GL, Muir DF, Saia F, Bortone AS, Densem CG, Owens CG, van der Kley F, Vis M, van Mourik MS, Costa G, Sykorova L, Lüske CM, Deutsch C, Kurucova J, Thoenes M, Bramlage P, Tamburino C, Barbanti M

Background Despite the availability of guidelines for the performance of transcatheter aortic valve implantation (TAVI), current treatment pathways vary between countries and institutions, which impact on the mean duration of postprocedure hospitalization. Methods and Results This was a prospective, multicenter registry of 502 patients to validate the appropriateness of discharge timing after transfemoral TAVI, using prespecified risk criteria from FAST-TAVI (Feasibility and Safety of Early Disc... Abstract

Cited 22 times since 2020 (4.1 per year) source: EuropePMC

Science advances, Volume 6, Issue 30, 24 4 2020, Pages eabb4685 When ontogeny recapitulates phylogeny: Fixed neurodevelopmental sequence of manipulative skills among primates. Heldstab SA, Isler K, Schuppli C, van Schaik CP

Neural development is highly conserved across distantly related species of different brain sizes. Here, we show that the development of manipulative complexity is equally cumulative across 36 primate species and also that its ontogeny recapitulates phylogeny. Furthermore, larger-brained species reach their adult skill levels later than smaller-brained ones, largely because they start later with the simplest techniques. These findings demonstrate that these motor behaviors are not modular and tha... Abstract

Cited 9 times since 2020 (1.7 per year) source: EuropePMC

Journal of medical Internet research, Volume 22, Issue 7, 24 4 2020, Pages e14861 An Internet-Based Psychological Intervention With a Serious Game to Improve Vitality, Psychological and Physical Condition, and Immune Function in Healthy Male Adults: Randomized Controlled Trial. Schakel L, Veldhuijzen DS, van Middendorp H, Prins C, Drittij AMHF, Vrieling F, Visser LG, Ottenhoff THM, Joosten SA, Evers AWM

Background: Recently, internet-based cognitive behavioral therapy (ICBT) and serious gaming interventions have been suggested to enhance accessibility to interventions and engagement in psychological interventions that aim to promote health outcomes. Few studies, however, have investigated their effectiveness in the context of simulated real-life challenges. Objective: We aimed to examine the effectivity of a guided ICBT combined with a serious gaming intervention in improving self-reported psyc... Abstract

Cited 4 times since 2020 (0.7 per year) source: EuropePMC

Developmental psychology, Volume 56, Issue 9, 23 4 2020, Pages 1623-1631 Let's talk action: Infant-directed speech facilitates infants' action learning. Schreiner MS, van Schaik JE, Sučević J, Hunnius S, Meyer M

Parents modulate their speech and their actions during infant-directed interactions, and these modulations facilitate infants' language and action learning, respectively. But do these behaviors and their benefits cross these modality boundaries? We investigated mothers' infant-directed speech and actions while they demonstrated the action-effects of 4 novel objects to their 14-month-old infants. Mothers (N = 35) spent the majority of the time either speaking or demonstrating the to-be-... Abstract

Cited 85 times since 2020 (15.9 per year) source: EuropePMC

Nature, Volume 583, Issue 7818, 22 4 2020, Pages 801-806 Global status and conservation potential of reef sharks. MacNeil MA, Chapman DD, Heupel M, Simpfendorfer CA, Heithaus M, Meekan M, Harvey E, Goetze J, Kiszka J, Bond ME, Currey-Randall LM, Speed CW, Sherman CS, Rees MJ, Udyawer V, Flowers KI, Clementi G, Valentin-Albanese J, Gorham T, Adam MS, Ali K, Pina-Amargós F, Angulo-Valdés JA, Asher J, Barcia LG, Beaufort O, Benjamin C, Bernard ATF, Berumen ML, Bierwagen S, Bonnema E, Bown RMK, Bradley D, Brooks E, Brown JJ, Buddo D, Burke P, Cáceres C, Cardeñosa D, Carrier JC, Caselle JE, Charloo V, Claverie T, Clua E, Cochran JEM, Cook N, Cramp J, D'Alberto B, de Graaf M, Dornhege M, Estep A, Fanovich L, Farabaugh NF, Fernando D, Flam AL, Floros C, Fourqurean V, Garla R, Gastrich K, George L, Graham R, Guttridge T, Hardenstine RS, Heck S, Henderson AC, Hertler H, Hueter R, Johnson M, Jupiter S, Kasana D, Kessel ST, Kiilu B, Kirata T, Kuguru B, Kyne F, Langlois T, Lédée EJI, Lindfield S, Luna-Acosta A, Maggs J, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Kaimuddin

Decades of overexploitation have devastated shark populations, leaving considerable doubt as to their ecological status1,2. Yet much of what is known about sharks has been inferred from catch records in industrial fisheries, whereas far less information is available about sharks that live in coastal habitats3. Here we address this knowledge gap using data from more than 15,000 standardized baited remote underwater video stations that were deployed on 371 reefs in 58 nations to estimate the conse... Abstract

Cited 4 times since 2020 (0.7 per year) source: EuropePMC

Frontiers in psychology, Volume 11, 21 3 2020, Pages 1665 Hands-On Exploration of Cubes' Floating and Sinking Benefits Children's Subsequent Buoyancy Predictions. van Schaik JE, Slim T, Franse RK, Raijmakers MEJ

Children accrue experiences with buoyancy on a daily basis, yet research paints a mixed picture of children's buoyancy knowledge. Whereas children's predictions and explanations of the floating and the sinking of common objects are often based on a single feature (e.g., mass or facts), children's predictions of novel cubes reveal solution strategies based on mass and volume integrations. Correspondingly, category learning theory suggests that categories (e.g., floaters vs. sinkers... Abstract

Cited 37 times since 2020 (6.9 per year) source: EuropePMC

Molecular therapy. Nucleic acids, Volume 21, 21 3 2020, Pages 932-953 Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia. van der Kwast RVCT, Parma L, van der Bent ML, van Ingen E, Baganha F, Peters HAB, Goossens EAC, Simons KH, Palmen M, de Vries MR, Quax PHA, Nossent AY

Adenosine-to-inosine (A-to-I) editing in the seed sequence of microRNAs can shift the microRNAs' targetomes and thus their function. Using public RNA-sequencing data, we identified 35 vasoactive microRNAs that are A-to-I edited. We quantified A-to-I editing of the primary (pri-)microRNAs in vascular fibroblasts and endothelial cells. Nine pri-microRNAs were indeed edited, and editing consistently increased under ischemia. We determined mature microRNA editing for the highest expressed micro... Abstract

Cited 179 times since 2020 (33.5 per year) source: EuropePMC

PLoS medicine, Volume 17, Issue 7, 21 3 2020, Pages e1003166 Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study. Teslya A, Pham TM, Godijk NG, Kretzschmar ME, Bootsma MCJ, Rozhnova G

Background: The coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every country in the world since it first emerged in China in December 2019. Many countries have implemented social distancing as a measure to "flatten the curve" of the ongoing epidemics. Evaluation of the impact of government-imposed social distancing and of other measures to control further spread of COVID-19 is urgent, especially because of... Abstract