9543 results
Cited 64 times since 2020 (12 per year)
source: EuropePMC
Journal of neurology,
Volume 268, Issue 2, 20 3 2020, Pages 403-408
Impact of the COVID-19 outbreak on acute stroke care.
Rinkel LA, Prick JCM, Slot RER, Sombroek NMA, Burggraaff J, Groot AE, Emmer BJ, Roos YBWEM, Brouwer MC, van den Berg-Vos RM, Majoie CBLM, Beenen LFM, van de Beek D, Visser MC, van Schaik SM, Coutinho JM
Background and purpose: There are concerns that the coronavirus disease 2019 (COVID-19) outbreak negatively affects the quality of care for acute cardiovascular conditions. We assessed the impact of the COVID-19 outbreak on trends in hospital admissions and workflow parameters of acute stroke care in Amsterdam, The Netherlands. Methods: We used data from the three hospitals that provide acute stroke care for the Amsterdam region. We compared two 7-week periods: one during the peak of the COVID-1...
Abstract
Journal of cardiology,
Volume 76, Issue 5, 19 3 2020, Pages 514-520
QT interval variability and heart rate turbulence are associated with clinical characteristics in congenital heart disease patients with a systemic right ventricle.
Zandstra T, Kiès P, Man SC, Maan A, Bootsma M, Vliegen H, Egorova A, Holman E, Schalij M, Jongbloed M
Background: QT interval variability (QTV) and heart rate turbulence (HRT) are measures of cardiac autonomic function, which, when abnormal, are correlated with ventricular arrhythmias and worse clinical outcome. This study aims to evaluate QTV and HRT in patients with a systemic right ventricle (RV) and to assess correlations with clinical characteristics. Methods: In a retrospective cohort study, QTV and HRT were derived from 24-h Holter registrations of patients with a systemic RV and healthy...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European urology,
Volume 78, Issue 4, 18 3 2020, Pages 492-493
Reply to Francesco Montorsi, Marco Bandini, Alberto Briganti, et al. Re-establishing the Role of Robot-assisted Radical Cystectomy After the 2020 EAU Muscle-invasive and Metastatic Bladder Cancer Guideline Panel Recommendations. Eur Urol 2020;78:489-91: Can Open and Robotic Radical Cystectomy be Considered Equally Effective in 2020?
Witjes JA, Ribal MJ, van der Heijden AG
Abstract
Cited 40 times since 2020 (7.5 per year)
source: EuropePMC
Cardiovascular diabetology,
Volume 19, Issue 1, 18 3 2020, Pages 113
Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry.
Won KB, Lee BK, Park HB, Heo R, Lee SE, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, de Araújo Gonçalves P, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Raff GL, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ
Background: The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the association between TyG index and coronary plaque progression (PP) using serial coronary computed tomography angiography (CCTA). Methods: A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent serial CCTA with available data on TyG index and diabetic status were analyzed from The Progression of AtheRosclerotic PlAque DetermIned by...
Abstract
Cited 451 times since 2020 (84.2 per year)
source: EuropePMC
The Lancet. Public health,
Volume 5, Issue 8, 16 3 2020, Pages e452-e459
Impact of delays on effectiveness of contact tracing strategies for COVID-19: a modelling study.
Kretzschmar ME, Rozhnova G, Bootsma MCJ, van Boven M, van de Wijgert JHHM, Bonten MJM
Background: In countries with declining numbers of confirmed cases of COVID-19, lockdown measures are gradually being lifted. However, even if most physical distancing measures are continued, other public health measures will be needed to control the epidemic. Contact tracing via conventional methods or mobile app technology is central to control strategies during de-escalation of physical distancing. We aimed to identify key factors for a contact tracing strategy to be successful. Methods: We e...
Abstract
Cited 7 times since 2020 (1.3 per year)
source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD,
Volume 30, Issue 12, 16 3 2020, Pages 2230-2241
The role of insulin resistance in the relation of visceral, abdominal subcutaneous and total body fat to cardiovascular function.
Paiman EHM, de Mutsert R, Widya RL, Rosendaal FR, Jukema JW, Lamb HJ
Background and aims: The separate cardiovascular effects of type 2 diabetes and adiposity remain to be examined. This study aimed to investigate the role of insulin resistance in the relations of visceral (VAT), abdominal subcutaneous (aSAT) adipose tissue and total body fat (TBF) to cardiovascular remodeling. Methods and results: In this cross-sectional analysis of the population-based Netherlands Epidemiology of Obesity study, 914 middle-aged individuals (46% men) were included. Participants u...
Abstract
Cited 127 times since 2020 (23.7 per year)
source: EuropePMC
Nature reviews. Urology,
Volume 17, Issue 9, 16 3 2020, Pages 513-525
Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer.
van Puffelen JH, Keating ST, Oosterwijk E, van der Heijden AG, Netea MG, Joosten LAB, Vermeulen SH
Intravesical BCG instillation is the gold-standard adjuvant immunotherapy for patients with high-risk non-muscle-invasive bladder cancer. However, the precise mechanism of action by which BCG asserts its beneficial effects is still unclear. BCG has been shown to induce a non-specific enhancement of the biological function in cells of the innate immune system, creating a de facto heterologous immunological memory that has been termed trained immunity. Trained immunity or innate immune memory enab...
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 22, Issue 1, 16 3 2020, Pages 52
Reduced right ventricular function on cardiovascular magnetic resonance imaging is associated with uteroplacental impairment in tetralogy of Fallot.
Siegmund AS, Willems TP, Pieper PG, Bilardo CM, Gorter TM, Bouma BJ, Jongbloed MRM, Sieswerda GT, Roos-Hesselink JW, van Dijk APJ, van Veldhuisen DJ, Dickinson MG
Background: Maternal right ventricular (RV) dysfunction (measured by echocardiography) is associated with impaired uteroplacental circulation, however echocardiography has important limitations in the assessment of RV function. We therefore aimed to investigate the association of pre-pregnancy RV and left ventricular (LV) function measured by cardiovascular magnetic resonance with uteroplacental Doppler flow parameters in pregnant women with repaired Tetralogy of Fallot (ToF). Methods: Women wit...
Abstract
Cited 40 times since 2020 (7.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 10, 15 3 2020, Pages 2162-2173
A Boosted Ensemble Algorithm for Determination of Plaque Stability in High-Risk Patients on Coronary CTA.
Al'Aref SJ, Singh G, Choi JW, Xu Z, Maliakal G, van Rosendael AR, Lee BC, Fatima Z, Andreini D, Bax JJ, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Lee SE, Leipsic JA, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Weirich HG, Cho I, Danad I, Han D, Heo R, Lee JH, Rizvi A, Stuijfzand WJ, Gransar H, Lu Y, Sung JM, Park HB, Berman DS, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Chang HJ, Lin FY, Baskaran L, Shaw LJ, Min JK
Objectives: This study sought to identify culprit lesion (CL) precursors among acute coronary syndrome (ACS) patients based on qualitative and quantitative computed tomography-based plaque characteristics. Background: Coronary computed tomography angiography (CTA) has been validated for patient-level prediction of ACS. However, the applicability of coronary CTA to CL assessment is not known. Methods: Utilizing the ICONIC (Incident COroNary Syndromes Identified by Computed Tomography) study, a ne...
Abstract
Cited 76 times since 2020 (14.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 33, Issue 10, 14 2 2020, Pages 1201-1208
Myocardial Work in Nonobstructive Hypertrophic Cardiomyopathy: Implications for Outcome.
Hiemstra YL, van der Bijl P, El Mahdiui M, Bax JJ, Delgado V, Marsan NA
Background: Noninvasive left ventricular (LV) pressure-strain loop analysis is emerging as a new echocardiographic method to evaluate LV function, integrating longitudinal strain by speckle-tracking analysis and sphygmomanometrically measured blood pressure to estimate myocardial work. The aims of this study were (1) to describe global and segmental myocardial work in patients with hypertrophic cardiomyopathy (HCM), (2) to assess the correlation between myocardial work and other echocardiographi...
Abstract
Cited 9 times since 2020 (1.7 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 21, Issue 14, 13 2 2020, Pages E4944
Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study.
Linssen PBC, Brunner-La Rocca HP, Schalkwijk CG, Beulens JWJ, Elders PJM, van der Heijden AA, Slieker RC, Stehouwer CDA, Henry RMA
Extracellular matrix protein turnover may play an important role in left atrial (LA) remodelling. The aim is to investigate the associations between matrix metalloproteinase (MMPs), tissue inhibitor of metalloproteinase (TIMP-1) and LA volume index (LAVI) and if these associations are independent of TIMP-1 levels. Participants from The Hoorn Study, a population-based cohort study (n = 674), underwent echocardiography. Serum MMPs (i.e., MMP-1, MMP-2, MMP-3, MMP-9, and MMP-10) and TIMP-1 levels we...
Abstract
Cited 36 times since 2020 (6.7 per year)
source: EuropePMC
PloS one,
Volume 15, Issue 7, 13 2 2020, Pages e0235228
Intimal and medial calcification in relation to cardiovascular risk factors.
Zwakenberg SR, de Jong PA, Hendriks EJ, Westerink J, Spiering W, de Borst GJ, Cramer MJ, Bartstra JW, Doesburg T, Rutters F, van der Heijden AA, Schalkwijk C, Schurgers LJ, van der Schouw YT, Beulens JWJ, SMART Study Group
Purpose: To assess specific risk factors and biomarkers associated with intimal arterial calcification (IAC) and medial arterial calcification (MAC). Methods: We conducted a cross-sectional study in patients with or at risk of vascular disease from the SMART study(n = 520) and the DCS cohort(n = 198). Non-contrast computed tomography scanning of the lower extremities was performed and calcification in the femoral and crural arteries was scored as absent, predominant IAC, predominant MAC or indis...
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
Campbell systematic reviews,
Volume 16, Issue 3, 12 2 2020, Pages e1101
PROTOCOL: Exercise interventions to improve back shape/posture, balance, falls and fear of falling in older adults with hyperkyphosis: A systematic review.
Duangkaew R, Bettany-Saltikov J, van Schaik P, Kandasamy G, Hogg J
Aim: The aim of this systematic review is to evaluate and synthesize published and unpublished literature on the effectiveness of a diverse range of exercise programs on back shape/posture, balance, falling and fear of falling in older people with hyperkyphosis. Objectives: The objective of this systematic review is to determine the effects of difference exercise programs on back shape/posture, balance, falling and fear of falling in older adults with hyperkyphosis.
Abstract
Cited 10 times since 2020 (1.9 per year)
source: EuropePMC
Progress in brain research,
Volume 254, 9 2 2020, Pages 89-111
Motion tracking in developmental research: Methods, considerations, and applications.
van Schaik JE, Dominici N
In this chapter, we explore the use of motion tracking methodology in developmental research. With motion tracking, also called motion capture, human movements can be precisely recorded and analyzed. Motion tracking provides developmental researchers with objective measurements of motor and (socio-)cognitive development. It can further be used to create carefully-controlled stimuli videos and can offer means of measuring development outside of the lab. We discuss three types of motion tracking t...
Abstract
Cited 10 times since 2020 (1.9 per year)
source: EuropePMC
International journal of colorectal disease,
Volume 35, Issue 11, 8 2 2020, Pages 2065-2071
Appendicular neoplasms and consequences in patients undergoing surgery for suspected acute appendicitis.
Bolmers MDM, de Jonge J, van Rossem CC, van Geloven AAW, Bemelman WA, Snapshot Appendicitis Collaborative Study group
Introduction: In patients treated with an appendectomy for acute appendicitis, the specimen is generally sent for histological evaluation. In an era of increasing non-operative treatment for acute appendicitis, it is important to know the incidence, the diagnostic accuracy, and treatment consequences of appendicular neoplasms that are found in acute appendicitis. We hypothesize that pre- and intra-operative parameters might predict an appendicular neoplasm. Methods: Data was used from our previo...
Abstract
Cited 22 times since 2020 (4.1 per year)
source: EuropePMC
RNA (New York, N.Y.),
Volume 26, Issue 10, 7 1 2020, Pages 1489-1506
Validation strategies for antibodies targeting modified ribonucleotides.
Weichmann F, Hett R, Schepers A, Ito-Kureha T, Flatley A, Slama K, Hastert FD, Angstman NB, Cardoso MC, König J, Hüttelmaier S, Dieterich C, Canzar S, Helm M, Heissmeyer V, Feederle R, Meister G
Chemical modifications are found on almost all RNAs and affect their coding and noncoding functions. The identification of m6A on mRNA and its important role in gene regulation stimulated the field to investigate whether additional modifications are present on mRNAs. Indeed, modifications including m1A, m5C, m7G, 2'-OMe, and Ψ were detected. However, since their abundances are low and tools used for their corroboration are often not well characterized, their physiological relevance remains...
Abstract
Cited 22 times since 2020 (4.1 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 33, Issue 10, 7 1 2020, Pages 1172-1179
Noninvasive Myocardial Work Indices 3 Months after ST-Segment Elevation Myocardial Infarction: Prevalence and Characteristics of Patients with Postinfarction Cardiac Remodeling.
Lustosa RP, van der Bijl P, El Mahdiui M, Montero-Cabezas JM, Kostyukevich MV, Ajmone Marsan N, Bax JJ, Delgado V
Background: Assessment of left ventricular (LV) remodeling after ST-segment elevation myocardial infarction (STEMI) is pivotal for patient management. Noninvasive myocardial work indices obtained from echocardiography-derived strain-pressure loops provide a new tool that permits characterization of LV mechanics. We aimed at characterizing myocardial work indices in patients with LV remodeling after STEMI versus patients without remodeling. Methods: Six-hundred STEMI patients were retrospectively...
Abstract
Cited 22 times since 2020 (4.1 per year)
source: EuropePMC
Nanoscale,
Volume 12, Issue 28, 1 1 2020, Pages 15236-15245
Tuning intermediate filament mechanics by variation of pH and ion charges.
Schepers AV, Lorenz C, Köster S
The cytoskeleton is formed by three types of filamentous proteins - microtubules, actin filaments, and intermediate filaments (IFs) - and enables cells to withstand external and internal forces. Vimentin is the most abundant IF protein in humans and assembles into 10 nm diameter filaments with remarkable mechanical properties, such as high extensibility and stability. It is, however, unclear to which extent these properties are influenced by the electrostatic environment. Here, we study the mech...
Abstract
Cited 51 times since 2020 (9.4 per year)
source: EuropePMC
World journal of surgery,
Volume 44, Issue 7, 1 1 2020, Pages 2211-2219
Defining Major Surgery: A Delphi Consensus Among European Surgical Association (ESA) Members.
Martin D, Mantziari S, Demartines N, Hübner M, ESA Study Group
Background: Major surgery is a term frequently used but poorly defined. The aim of the present study was to reach a consensus in the definition of major surgery within a panel of expert surgeons from the European Surgical Association (ESA). Methods: A 3-round Delphi process was performed. All ESA members were invited to participate in the expert panel. In round 1, experts were inquired by open- and closed-ended questions on potential criteria to define major surgery. Results were analyzed and pr...
Abstract
Cited 28 times since 2020 (5.2 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 105, Issue 7, 1 1 2020, Pages dgaa173
Plasma Metabolomics Identifies Markers of Impaired Renal Function: A Meta-analysis of 3089 Persons with Type 2 Diabetes.
Tofte N, Vogelzangs N, Mook-Kanamori D, Brahimaj A, Nano J, Ahmadizar F, van Dijk KW, Frimodt-Møller M, Arts I, Beulens JWJ, Rutters F, van der Heijden AA, Kavousi M, Stehouwer CDA, Nijpels G, van Greevenbroek MMJ, van der Kallen CJH, Rossing P, Ahluwalia TS, 't Hart LM
Context: There is a need for novel biomarkers and better understanding of the pathophysiology of diabetic kidney disease. Objective: To investigate associations between plasma metabolites and kidney function in people with type 2 diabetes (T2D). Design: 3089 samples from individuals with T2D, collected between 1999 and 2015, from 5 independent Dutch cohort studies were included. Up to 7 years follow-up was available in 1100 individuals from 2 of the cohorts. Main outcome measures: Plasma metabol...
Abstract
