9543 results
Cited 43 times since 2020 (7.6 per year)
source: EuropePMC
Circulation research,
Volume 127, Issue 2, 6 1 2020, Pages 229-243
Identification of Functional Variant Enhancers Associated With Atrial Fibrillation.
van Ouwerkerk AF, Bosada FM, Liu J, Zhang J, van Duijvenboden K, Chaffin M, Tucker NR, Pijnappels D, Ellinor PT, Barnett P, de Vries AAF, Christoffels VM
Rationale: Genome-wide association studies have identified a large number of common variants (single-nucleotide polymorphisms) associated with atrial fibrillation (AF). These variants are located mainly in noncoding regions of the genome and likely include variants that modulate the function of transcriptional regulatory elements (REs) such as enhancers. However, the actual REs modulated by variants and the target genes of such REs remain to be identified. Thus, the biological mechanisms by whic...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Heart and vessels,
Volume 35, Issue 9, 4 1 2020, Pages 1290-1298
Influence of long-standing pulmonary arterial hypertension and its severity on pulmonary artery aneurysm development.
Nuche J, Montero-Cabezas JM, Lareo A, Huertas S, Jiménez López-Guarch C, Velázquez Martín M, Alonso Charterina S, Revilla Ostolaza Y, Delgado JF, Arribas Ynsaurriaga F, Escribano Subías P
Pulmonary artery aneurysm (PAA) is a common finding in patients with long-term pulmonary arterial hypertension (PAH). The influence of PAH severity in the development of PAA remains unclear. We sought to determine whether PAA development is related to PAH severity and whether treatment optimization based on risk profile estimation is effective to stop pulmonary artery (PA) enlargement. This is a retrospective study of 125 PAH patients who underwent an imaging test (computed tomography or magneti...
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
Journal of cardiology,
Volume 76, Issue 3, 4 1 2020, Pages 287-294
Blood biomarkers in patients with bicuspid aortic valve disease.
Bons LR, Geenen LW, van den Hoven AT, Dik WA, van den Bosch AE, Duijnhouwer AL, Siebelink HJ, Budde RPJ, Boersma E, Wessels MW, van de Laar IMBH, DeRuiter MC, Goumans MJ, Loeys BL, Roos-Hesselink JW
Background: Patients with a bicuspid aortic valve (BAV) are at risk of developing valve deterioration and aortic dilatation. We aimed to investigate whether blood biomarkers are associated with disease stage in patients with BAV. Methods: Serum levels of high sensitivity C-reactive protein (hsCRP), high sensitivity troponin T (hsTnT), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and total transforming growth factor-beta 1 (TGF-ß1) were measured in adult BAV patients with valve dysfunct...
Abstract
Cited 6 times since 2020 (1.1 per year)
source: EuropePMC
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation,
Volume 29, Issue 8, 4 1 2020, Pages 2231-2239
Minimal important change in physical function in trauma patients: a study using the short musculoskeletal function assessment.
de Graaf MW, Reininga IHF, Heineman E, El Moumni M
Purpose: The Short Musculoskeletal Function Assessment (SMFA) questionnaire can be used to evaluate physical functioning in patients with traumatic injuries. It is not known what change in score reflects a meaningful change to patients. The aim was to determine minimal important change (MIC) values of the subscales (0-100) of the Dutch SMFA-NL in a sample of patients with a broad range of injuries. Methods: Patients between 18 and 65 years of age completed the SMFA-NL and the Global Rating of Ef...
Abstract
Cited 28 times since 2020 (5 per year)
source: EuropePMC
Diabetologia,
Volume 63, Issue 6, 3 1 2020, Pages 1110-1119
Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting.
van der Heijden AA, Nijpels G, Badloe F, Lovejoy HL, Peelen LM, Feenstra TL, Moons KGM, Slieker RC, Herings RMC, Elders PJM, Beulens JW
Aims/hypothesis: The aims of this study were to identify all published prognostic models predicting retinopathy risk applicable to people with type 2 diabetes, to assess their quality and accuracy, and to validate their predictive accuracy in a head-to-head comparison using an independent type 2 diabetes cohort. Methods: A systematic search was performed in PubMed and Embase in December 2019. Studies that met the following criteria were included: (1) the model was applicable in type 2 diabetes;...
Abstract
Cited 14 times since 2020 (2.5 per year)
source: EuropePMC
Japan journal of nursing science : JJNS,
Volume 17, Issue 4, 2 1 2020, Pages e12338
Effects of three different methods used during heel lance procedures on pain level in term neonates.
Yilmaz D, Inal S
Aim: This study aims to experimentally determine effects of three different methods (swaddling; swaddling and holding; swaddling, holding and breastfeeding) used during heel lancing on pain levels in healthy term neonates. Methods: This study was a prospective, randomized controlled trial. The sample of newborns (n = 160) were allocated to the groups (group 1, control; group 2, swaddling; group 3, swaddling and holding; group 4, swaddling, holding and breastfeeding) by blocked randomization. The...
Abstract
Cited 36 times since 2020 (6.4 per year)
source: EuropePMC
JAMA internal medicine,
Volume 180, Issue 4, 1 1 2020, Pages 533-541
Effect of No Prehydration vs Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography in the Prevention of Postcontrast Acute Kidney Injury in Adults With Chronic Kidney Disease: The Kompas Randomized Clinical Trial.
Timal RJ, Kooiman J, Sijpkens YWJ, de Vries JPM, Verberk-Jonkers IJAM, Brulez HFH, van Buren M, van der Molen AJ, Cannegieter SC, Putter H, van den Hout WB, Jukema JW, Rabelink TJ, Huisman MV
Importance: Prevention of postcontrast acute kidney injury in patients with stage 3 chronic kidney disease (CKD) by means of prehydration has been standard care for years. However, evidence for the need for prehydration in this group is limited. Objective: To assess the renal safety of omitting prophylactic prehydration prior to iodine-based contrast media administration in patients with stage 3 CKD. Design, setting, and participants: The Kompas trial was a multicenter, noninferiority, randomize...
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
Medicine,
Volume 99, Issue 17, 1 1 2020, Pages e19851
Pain acceptance levels of patients with chronic pain.
Çinar HG, Yilmaz D, Akin E
This study was conducted with the aim of determining pain acceptance levels in patients with chronic pain attending an algology outpatients' department.The research was conducted as a descriptive and cross-sectional study. The population of the study consisted of 97 patients with chronic pain who attended the Algology Outpatients' Department of the Health Implementation and Research Center of Bursa Uludağ University. A Patient Description Form and a Chronic Pain Acceptance Questionnair...
Abstract
Cited 3 times since 2020 (0.5 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 57, Issue 4, 1 1 2020, Pages 815
Concomitant aortic root enlargement is perhaps safe, but is it also effective?
Vriesendorp MD, de Lind van Wijngaarden RAF, Klautz RJM
Abstract
Cited 20 times since 2020 (3.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 4, 1 1 2020, Pages 357-362
The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: a survey by EACVI.
Michalski B, Dweck MR, Marsan NA, Cameli M, D'Andrea A, Carvalho RF, Holte E, Podlesnikar T, Manka R, Haugaa KH
Aortic stenosis (AS) is the most prevalent valvular disease in developed countries, with a prevalence that is set to expand further with an ageing population. The most recent guidelines on valvular heart disease published by the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery, aim to standardize the diagnosis and management of valvular heart diseases. The imaging criteria of the current guidelines are mostly based on EACVI Recommendations, with an appropri...
Abstract
Cited 57 times since 2020 (10.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 16, 1 1 2020, Pages 1869-1877
Age-Related Variations in Takotsubo Syndrome.
Cammann VL, Szawan KA, Stähli BE, Kato K, Budnik M, Wischnewsky M, Dreiding S, Levinson RA, Di Vece D, Gili S, Citro R, Bossone E, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Heiner S, D'Ascenzo F, Dichtl W, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Shoji T, Ishibashi I, Takahara M, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm M, Maier LS, Pinto FJ, Widimský P, Felix SB, Braun-Dullaeus RC, Rottbauer W, Hasenfu
Background: Takotsubo syndrome (TTS) occurs predominantly in post-menopausal women but is also found in younger patients. Objectives: This study aimed to investigate age-related differences in TTS. Methods: Patients diagnosed with TTS and enrolled in the International Takotsubo Registry between January 2011 and February 2017 were included in this analysis and were stratified by age (younger: ≤50 years, middle-age: 51 to 74 years, elderly: ≥75 years). Baseline characteristics, hospital course, as...
Abstract
Cited 30 times since 2020 (5.3 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 4, 1 1 2020, Pages 363-374
Increased long-term mortality in women with high left ventricular ejection fraction: data from the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) long-term registry.
Gebhard C, Maredziak M, Messerli M, Buechel RR, Lin F, Gransar H, Achenbach S, Al-Mallah MH, Andreini D, Bax JJ, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kim YJ, Leipsic J, Maffei E, Marques H, Gonçalves PA, Pontone G, Raff GL, Rubinshtein R, Shaw LJ, Villines TC, Lu Y, Jones EC, Peña JM, Min JK, Kaufmann PA
Aims: There are significant sex-specific differences in left ventricular ejection fraction (LVEF), with a higher LVEF being observed in women. We sought to assess the clinical relevance of an increased LVEF in women and men. Methods and results: A total of 4632 patients from the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) registry (44.8% women; mean age 58.7 ± 13.2 years in men and 59.5 ± 13.3 years in women, P = 0.05), in whom LVEF was measur...
Abstract
JACC. Cardiovascular imaging,
Volume 13, Issue 4, 1 1 2020, Pages 1099
The Authors Reply: Computed Tomography Angiography-Based Risk Discrimination: An Established Bright Future for Prognostication.
van Rosendael AR, Min JK, Shaw LJ, Bax JJ
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Annals of surgery,
Volume 271, Issue 4, 1 1 2020, Pages 781-789
Variation in Surgical Treatment of Abdominal Aortic Aneurysms With Small Aortic Diameters in the Netherlands.
Karthaus EG, Vahl A, van der Werf LR, Elsman BHP, Van Herwaarden JA, Wouters MWJM, Hamming JF
Objective: To evaluate reasons to deviate from aneurysm diameter thresholds, and focus on the difference in how Dutch vascular surgical units (VSUs) perceive their deviation and their actual deviation. Background: Guidelines recommend surgical treatment for asymptomatic abdominal aortic aneurysms (AAAs) with a diameter of at least 55 mm for men and 50 mm for women. We evaluate reasons to deviate from these guidelines, and focus on the difference in how Dutch vascular surgical units (VSUs) percei...
Abstract
Cited 58 times since 2020 (10.3 per year)
source: EuropePMC
Alimentary pharmacology & therapeutics,
Volume 51, Issue 9, 1 1 2020, Pages 880-888
Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry.
Biemans VBC, Sleutjes JAM, de Vries AC, Bodelier AGL, Dijkstra G, Oldenburg B, Löwenberg M, van Bodegraven AA, van der Meulen-de Jong AE, de Boer NKH, Srivastava N, West RL, Römkens TEH, Horjus Talabur Horje CS, Jansen JM, van der Woude CJ, Hoekstra J, Weersma RK, van Schaik FDM, Hoentjen F, Pierik MJ, Dutch Initiative on Crohn and Colitis (ICC)
Background: Tofacitinib is a Janus kinase inhibitor approved for the treatment of ulcerative colitis (UC). Aim: To evaluate effectiveness, safety and use of tofacitinib in daily practice. Methods: UC patients initiating tofacitinib were prospectively enrolled in 15 hospitals in the Netherlands. Corticosteroid-free clinical remission (short clinical colitis activity index [SCCAI] ≤2), biochemical remission (faecal calprotectin level ≤250 µg/g), combined corticosteroid-free clinical and biochemica...
Abstract
Cited 6 times since 2020 (1.1 per year)
source: EuropePMC
Perception,
Volume 49, Issue 4, 1 1 2020, Pages 484-487
When Is Moving a Cursor With a Computer Mouse Intuitive?
Brenner E, de Graaf ML, Stam MJ, Schonwetter M, Smeets JBJ, van Beers RJ
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Journal of graduate medical education,
Volume 12, Issue 2, 1 1 2020, Pages 153-158
E-ASSESS: Creating an EPA Assessment Tool for Structured Simulated Emergency Scenarios.
Andler C, Daya S, Kowalek K, Boscardin C, van Schaik SM
Background: The entrustable professional activity (EPA) assessment framework allows supervisors to assign entrustment levels to physician trainees for specific activities. Limited opportunity for direct observation of trainees hampers entrustment decisions, in particular for infrequently performed activities. Simulation allows for direct observation, so tools to assess performance of EPAs in simulation could potentially provide additional data to complement clinical assessments. Objective: We de...
Abstract
Cited 69 times since 2020 (12.2 per year)
source: EuropePMC
JAMA network open,
Volume 3, Issue 4, 1 1 2020, Pages e202165
Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction: A Randomized Clinical Trial.
Treskes RW, van Winden LAM, van Keulen N, van der Velde ET, Beeres SLMA, Atsma DE, Schalij MJ
Importance: Smart technology via smartphone-compatible devices might improve blood pressure (BP) regulation in patients after myocardial infarction. Objectives: To investigate whether smart technology in clinical practice can improve BP regulation and to evaluate the feasibility of such an intervention. Design, setting, and participants: This study was an investigator-initiated, single-center, nonblinded, feasibility, randomized clinical trial conducted at the Department of Cardiology of the Lei...
Abstract
Cited 5 times since 2020 (0.9 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 67, 1 1 2020, Pages 346-353
Vascular Surgeons' Views on Ejaculation Disorders After Abdominal Aortic Surgery: Results of a Dutch Survey.
van Schaik J, van der Vorst JR, Hamming JF, Elzevier HW, Nicolai MPJ
Background: The aim of this study is to evaluate vascular surgeons' knowledge and appreciation of ejaculatory dysfunction after open aortic aneurysm repair and the knowledge of possible nerve-preserving techniques. Methods: A Dutch national survey was conducted on sexual counseling in the case of open aortic surgery. For this purpose, a designed questionnaire based on a review of the literature in the field and on other surveys aiming to analyze care for sexual health by medical specialists...
Abstract
Cited 4 times since 2020 (0.7 per year)
source: EuropePMC
World journal of surgery,
Volume 44, Issue 4, 1 1 2020, Pages 1309-1315
Is Ischemia-Modified Albumin a Reliable Marker in Accurate Diagnosis of Appendicitis in Children?
Ulusoy E, Çitlenbik H, Akgül F, Öztürk A, Şık N, Ulusoy O, Küme T, Yılmaz D, Duman M
Background: Acute appendicitis is one of the most common abdominal emergencies. Despite all improvements in diagnostic techniques, there are still ongoing problems as proper diagnosis, misdiagnosis and perforated appendicitis. The aim of this study is to demonstrate the clinical value of IMA in patients with appendicitis and to determine the accurate diagnosis of appendicitis in clinically suspected patients. Methods: Pediatric patients with acute abdominal pain who had the Pediatric Appendiciti...
Abstract
