9543 results
Cited 12 times since 2020 (2 per year)
source: EuropePMC
Critical care medicine,
Volume 48, Issue 1, 1 1 2020, Pages e1-e8
Online Learning and Residents' Acquisition of Mechanical Ventilation Knowledge: Sequencing Matters.
Wolbrink TA, van Schaik SM, Turner DA, Staffa SJ, Keller E, Boyer DL, Chong G, Cross J, Del Castillo S, Feng A, Hum RS, Jacob James E, Johnson A, Kandil S, Kneyber M, Rameshkumar R, Levin A, Lodha R, Jayashree M, Olivero A, Oberender F, Panesar RS, Pooni PA, Rehder KJ, Sankaranarayanan S, Scheffler M, Sharara-Chami R, Siems AL, Padur Sivaraman R, Tegtmeyer K, Valentine S, Villois F, von Saint Andre-von Arnim A, Winkler M, Dede C, Burns JP, Game-based Education in Residency (GamER) Study Group
Objective: Rapid advancements in medicine and changing standards in medical education require new, efficient educational strategies. We investigated whether an online intervention could increase residents' knowledge and improve knowledge retention in mechanical ventilation when compared with a clinical rotation and whether the timing of intervention had an impact on overall knowledge gains. Design: A prospective, interventional crossover study conducted from October 2015 to December 2017. S...
Abstract
Cited 9 times since 2020 (1.5 per year)
source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
Volume 35, Issue 1, 1 1 2020, Pages 176-183
Serum magnesium, hepatocyte nuclear factor 1β genotype and post-transplant diabetes mellitus: a prospective study.
van der Burgh AC, Moes A, Kieboom BCT, van Gelder T, Zietse R, van Schaik RHN, Hesselink DA, Hoorn EJ
Background: Retrospective studies suggest that tacrolimus-induced hypomagnesaemia is a risk factor for post-transplant diabetes mellitus (PTDM), but prospective studies are lacking. Methods: This was a prospective study with measurements of serum magnesium and tacrolimus at pre-specified time points in the first year after living donor kidney transplantation (KT). The role of single nucleotide polymorphisms (SNPs) in hepatocyte nuclear factor 1β (HNF1β) was also explored because HNF1β regulates...
Abstract
Cited 339 times since 2020 (57.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 2, 1 1 2020, Pages 133-144
Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome.
Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Committees and Investigators
Background: Lipoprotein(a) concentration is associated with cardiovascular events. Alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, lowers lipoprotein(a) and low-density lipoprotein cholesterol (LDL-C). Objectives: A pre-specified analysis of the placebo-controlled ODYSSEY Outcomes trial in patients with recent acute coronary syndrome (ACS) determined whether alirocumab-induced changes in lipoprotein(a) and LDL-C independently predicted major adverse cardiovascular events (...
Abstract
Cited 2 times since 2020 (0.3 per year)
source: EuropePMC
Current medical imaging,
Volume 16, Issue 9, 1 1 2020, Pages 1105-1110
Evaluation of Mandibular Third Molar Region in a Turkish Population Using Cone-Beam Computed Tomography.
Orhan BK, Yılmaz D, Ozemre MO, Kamburoğlu K, Gulen O, Gulsahi A
Objectives: To evaluate impacted mandibular third molar tooth region and obtain linear measurements using CBCT images and to assess the relationship between the impacted third molar and the mandibular canal. Methods: CBCT scans of 351 patients (208 females, 143 males) were assessed. Age, gender, and impaction site were recorded for each patient. The relationship of third molars with the vertical axis of second molars, 2nd molar resorption and the relationship between third molar apices and the m...
Abstract
Cited 2 times since 2020 (0.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue 1, 1 1 2020, Pages 59
Correction to: Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group.
Pustjens TFS, Appelman Y, Damman P, Ten Berg JM, Jukema JW, de Winter RJ, Agema WRP, van der Wielen MLJ, Arslan F, Rasoul S, van 't Hof AWJ
Correction to: Neth Heart J 2019 https://doi.org/10.1007/s12471-019-01344-6 The reference to the term acute coronary syndrome with normal or near-normal (non-obstructive) coronary arteries (ACSNNOCA) from Manolis et al. (2018) was inadvertently omitted to the original published article. Therefore, ….
Abstract
Cited 29 times since 2019 (4.9 per year)
source: EuropePMC
BMC psychiatry,
Volume 19, Issue 1, 30 5 2020, Pages 425
The impact of depression and anxiety treatment on biological aging and metabolic stress: study protocol of the MOod treatment with antidepressants or running (MOTAR) study.
Lever-van Milligen BA, Verhoeven JE, Schmaal L, van Velzen LS, Révész D, Black CN, Han LKM, Horsfall M, Batelaan NM, van Balkom AJLM, van Schaik DJF, van Oppen P, Penninx BWJH
Background: Depressive and anxiety disorders have shown to be associated to premature or advanced biological aging and consequently to adversely impact somatic health. Treatments with antidepressant medication or running therapy are both found to be effective for many but not all patients with mood and anxiety disorders. These interventions may, however, work through different pathophysiological mechanisms and could differ in their impact on biological aging and somatic health. This study protoc...
Abstract
Cited 34 times since 2019 (5.8 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 9, Issue 1, 30 5 2020, Pages E91
Why Uptake of Blended Internet-Based Interventions for Depression Is Challenging: A Qualitative Study on Therapists' Perspectives.
Mol M, van Genugten C, Dozeman E, van Schaik DJF, Draisma S, Riper H, Smit JH
(1) Background: Blended cognitive behavioral therapy (bCBT; online and face-to-face sessions) seems a promising alternative alongside regular face-to-face CBT depression treatment in specialized mental health care organizations. Therapists are key in the uptake of bCBT. This study focuses on therapists' perspectives on usability, satisfaction, and factors that promote or hinder the use of bCBT in routine practice; (2) Methods: Three focus groups (n = 8, n = 7, n = 6) and semi-structured in-...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: Scopus
The American journal of cardiology,
Volume 125, Issue 6, 27 4 2019, Pages 948-955
Prognostic Influence of Feature Tracking Multidetector Row Computed Tomography-Derived Left Ventricular Global Longitudinal Strain in Patients with Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation.
Gegenava T, van der Bijl P, Vollema EM, van der Kley F, de Weger A, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Computed tomography plays a central role in the evaluation of patients with severe aortic stenosis who underwent transcatheter aortic valve implantation (TAVI). Advances in left ventricular (LV) analysis with multidetector row computed tomography (MDCT) permit measurement of LV global longitudinal strain (GLS). The present study aimed at evaluating the association between feature tracking (FT) MDCT derived LV GLS and all-cause mortality in patients treated with TAVI. A total of 214 patients with...
Abstract
Cited 30 times since 2019 (5.1 per year)
source: EuropePMC
Cells,
Volume 9, Issue 1, 25 4 2019, Pages E61
An Emerging Role for isomiRs and the microRNA Epitranscriptome in Neovascularization.
van der Kwast RVCT, Quax PHA, Nossent AY
Therapeutic neovascularization can facilitate blood flow recovery in patients with ischemic cardiovascular disease, the leading cause of death worldwide. Neovascularization encompasses both angiogenesis, the sprouting of new capillaries from existing vessels, and arteriogenesis, the maturation of preexisting collateral arterioles into fully functional arteries. Both angiogenesis and arteriogenesis are highly multifactorial processes that require a multifactorial regulator to be stimulated simult...
Abstract
Cited 41 times since 2019 (6.9 per year)
source: EuropePMC
Scientific reports,
Volume 9, Issue 1, 24 4 2019, Pages 19788
Silicon and salicylic acid confer high-pH stress tolerance in tomato seedlings.
Khan A, Kamran M, Imran M, Al-Harrasi A, Al-Rawahi A, Al-Amri I, Lee IJ, Khan AL
Alkalinity is a known threat to crop plant growth and production, yet the role of exogenous silicon (Si) and salicylic acid (SA) application has been largely unexplored. Here, we sought to understand the beneficial impacts of Si and SA on tomato seedlings during high-pH (9.0) stress. Results showed that Si- and SA-treated plants displayed higher biomass, chlorophyll contents, relative leaf water and better root system than none-treated plants under alkaline conditions. Both Si and SA counteracte...
Abstract
Cited 90 times since 2019 (15.2 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 9, Issue 1, 24 4 2019, Pages e013841
Association Between Blood Pressure Variability and Cerebral Small-Vessel Disease: A Systematic Review and Meta-Analysis.
Tully PJ, Yano Y, Launer LJ, Kario K, Nagai M, Mooijaart SP, Claassen JAHR, Lattanzi S, Vincent AD, Tzourio C, Variability in Blood Pressure and Brain Health Consortium †, Variability in Blood Pressure and Brain Health Consortium†
Background Research links blood pressure variability (BPV) with stroke; however, the association with cerebral small-vessel disease (CSVD) remains unclear. As BPV and mean blood pressure are interrelated, it remains uncertain whether BPV adds additional information to understanding cerebrovascular morphological characteristics. Methods and Results A systematic review was performed from inception until March 3, 2019. Eligibility criteria included population, adults without stroke (
Abstract
Cited 31 times since 2019 (5.2 per year)
source: EuropePMC
European journal of heart failure,
Volume 22, Issue 2, 20 3 2019, Pages 330-337
Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry.
D'Ascenzo F, Gili S, Bertaina M, Iannaccone M, Cammann VL, Di Vece D, Kato K, Saglietto A, Szawan KA, Frangieh AH, Boffini B, Annaratone M, Sarcon A, Levinson RA, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Horowitz JD, Kozel M, Tousek P, Widimský P, Gilyarova E, Shilova A, Gilyarov M, Biondi-Zoccai G, Winchester DE, Ukena C, Neuhaus M, Bax JJ, Prasad A, Di Mario C, Böhm M, Gasparini M, Ruschitzka F, Bossone E, Citro R, Rinaldi M, De Ferrari GM, Lüscher T, Ghadri JR, Templin C
Aims: The aim of the present study was to investigate the impact of aspirin on prognosis in takotsubo syndrome (TTS). Methods and results: Patients from the International Takotsubo (InterTAK) Registry were categorized into two groups based on aspirin prescription at discharge. A comparison of clinical outcomes between groups was performed using an adjusted analysis with propensity score (PS) stratification; results from the unadjusted analysis were also reported to note the effect of the PS adju...
Abstract
Cited 50 times since 2019 (8.4 per year)
source: EuropePMC
Medical education,
Volume 54, Issue 3, 20 3 2019, Pages 205-216
Conceptualising spaced learning in health professions education: A scoping review.
Versteeg M, Hendriks RA, Thomas A, Ommering BWC, Steendijk P
Objectives: To investigate the definitions and applications of 'spaced learning' and to propose future directions for advancing its study and practice in health professions education. Method: The authors searched five online databases for articles published on spaced learning in health professions education prior to February 2018. Two researchers independently screened articles for eligibility with set inclusion criteria. They extracted and analysed key data using both quantitative and...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
Forensic science international,
Volume 307, 19 3 2019, Pages 110102
Chemical attribution of the home-made explosive ETN - Part I: Liquid chromatography-mass spectrometry analysis of partially nitrated erythritol impurities.
Bezemer K, McLennan L, van Duin L, Kuijpers CJ, Koeberg M, van den Elshout J, van der Heijden A, Busby T, Yevdokimov A, Schoenmakers P, Smith J, Oxley J, van Asten A
Erythritol tetranitrate (ETN) was prepared independently by two research groups from the USA and the Netherlands. The partially nitrated impurities present in ETN were studied using liquid chromatography-mass spectrometry to address the ultimate challenge in forensic explosives investigations, i.e., providing chemical and tactical information on the production and origin of the explosive material found at a crime scene. Accurate quantification of the tri-nitrated byproduct erythritol trinitrate...
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
Clinical case reports,
Volume 8, Issue 1, 17 3 2019, Pages 215-216
Caseous calcification of the mitral annulus assessed by multimodality imaging.
Sala ML, van Dijkman PRM, Kuijpers D
Physicians may not be familiar with caseous calcification of the mitral annulus. It can therefore easily be mistaken for other conditions including tumors. In the appropriate clinical context, by using multimodality imaging, a correct diagnosis can be made, and patient concern or even unnecessary surgery can be avoided.
Abstract
Cited 15 times since 2019 (2.5 per year)
source: EuropePMC
Travel medicine and infectious disease,
Volume 33, 17 3 2019, Pages 101547
Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in a population of Dutch travellers: A cross-sectional study.
Arcilla MS, Van Hattem JM, Bootsma MCJ, van Genderen PJJ, Goorhuis A, Grobusch MP, Klaassen CHW, Oude Lashof AM, Schultsz C, Stobberingh EE, de Jong MD, Penders J, Verbrugh HA, Melles DC
Background: We investigated prevalence and predictive factors for ESBL-E carriage in a population of mostly travellers prior to their travel (n = 2216). In addition, we examined ESBL genotype before travel and compared these to returning travellers. Method: A questionnaire and faecal sample were collected before travel, and a second faecal sample was collected immediately after travel. Faecal samples were analysed for ESBL-E, with genotypic characterization by PCR and sequencing. Risk factors fo...
Abstract
Cited 8 times since 2019 (1.3 per year)
source: EuropePMC
The Canadian journal of cardiology,
Volume 36, Issue 9, 17 3 2019, Pages 1525-1533
Myocardial Deformation in the Systemic Right Ventricle: Strain Imaging Improves Prediction of the Failing Heart.
Woudstra OI, van Dissel AC, van der Bom T, de Bruin-Bon RHACM, van Melle JP, van Dijk APJ, Vliegen HW, Mulder BJM, Tanck MWT, Meijboom FJ, Bouma BJ
Background: Predicting heart failure events in patients with a systemic right ventricle (sRV) due to transposition of the great arteries (TGA) is important for timely intensification of follow-up. This study assessed the value of strain compared with currently used parameters as predictor for heart failure-free survival in patients with sRV. Methods: In participants of a multicentre trial, speckle-tracking echocardiography (STE) was performed to assess global longitudinal strain (GLS), mechanica...
Abstract
Cited 53 times since 2019 (8.9 per year)
source: EuropePMC
Journal of lipid research,
Volume 61, Issue 3, 16 3 2019, Pages 365-375
Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice.
Pouwer MG, Pieterman EJ, Worms N, Keijzer N, Jukema JW, Gromada J, Gusarova V, Princen HMG
Atherosclerosis-related CVD causes nearly 20 million deaths annually. Most patients are treated after plaques develop, so therapies must regress existing lesions. Current therapies reduce plaque volume, but targeting all apoB-containing lipoproteins with intensive combinations that include alirocumab or evinacumab, monoclonal antibodies against cholesterol-regulating proprotein convertase subtilisin/kexin type 9 and angiopoietin-like protein 3, may provide more benefit. We investigated the effec...
Abstract
Cited 79 times since 2019 (13.3 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 40, Issue 2, 12 2 2019, Pages 350-364
Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis.
Wang G, Kostidis S, Tiemeier GL, Sol WMPJ, de Vries MR, Giera M, Carmeliet P, van den Berg BM, Rabelink TJ
Objective: Endothelial cells exposed to laminar shear stress express a thick glycocalyx on their surface that plays an important role in reducing vascular permeability and endothelial anti-inflammatory, antithrombotic, and antiangiogenic properties. Production and maintenance of this glycocalyx layer is dependent on cellular carbohydrate synthesis, but its regulation is still unknown. Approach and Results: Here, we show that biosynthesis of the major structural component of the endothelial glyco...
Abstract
Cited 28 times since 2019 (4.7 per year)
source: EuropePMC
Cardiovascular diabetology,
Volume 18, Issue 1, 12 2 2019, Pages 170
Visit-to-visit variability of glycemia and vascular complications: the Hoorn Diabetes Care System cohort.
Slieker RC, van der Heijden AAWH, Nijpels G, Elders PJM, 't Hart LM, Beulens JWJ
Background: Glycemic variation has been suggested to be a risk factor for diabetes-related complications. Previous studies did not address confounding of diabetes duration, number of visits and length of follow-up. Here, we characterize glycemic variability over time and whether its relation to diabetes-related complications and mortality is independent from diabetes- and follow-up duration. Materials and methods: Individuals with type 2 diabetes (n = 6770) from the Hoorn Diabetes Care System co...
Abstract
