9543 results
Cited 6 times since 2019 (0.9 per year)
source: EuropePMC
Healthcare (Basel, Switzerland),
Volume 7, Issue 2, 20 3 2019, Pages E78
The Information Needs of Adolescent Idiopathic Scoliosis Patients and Their Parents in the UK: An Online Survey.
Wellburn S, van Schaik P, Bettany-Saltikov J
Patients' involvement in decision-making regarding their own health care is considered to be of great importance. However, their information needs are frequently reported to be unfulfilled. Few studies have investigated the knowledge, information and support needs of adolescent idiopathic scoliosis (AIS) patients and their families. Furthermore, previous studies have predominantly focussed on information needs relating to surgery. No previous studies have been conducted to specifically iden...
Abstract
Cited 9 times since 2019 (1.4 per year)
source: EuropePMC
Seminars in thoracic and cardiovascular surgery,
Volume 31, Issue 4, 20 3 2019, Pages 643-649
Aortic Valve Surgery in Nonelderly Patients: Insights Gained From AVIATOR.
Lansac E, Youssefi P, de Heer F, Bavaria J, De Kerchove L, El-Hamamsy I, Elkhoury G, Enriquez-Sarano M, Jondeau LG, Kluin J, Pibarot P, Schäfers HJ, Vanoverschelde JL, Takkenberg JJM, Aortic Valve Repair Research Network Investigators from the Heart Valve Society, Collaborators
Aortic valve surgery in non-elderly patients represents a very challenging patient population. The younger the patient is at the point of aortic valve intervention, the longer their anticipated life expectancy will be, with longer exposure to valve-related complications and risk for re-operation. Although the latest international guidelines recommend aortic valve repair in patients with aortic valve insufficiency, what we see in the real world is that the vast majority of these aortic valves are...
Abstract
Cited 4 times since 2019 (0.6 per year)
source: EuropePMC
European radiology experimental,
Volume 3, Issue 1, 20 3 2019, Pages 24
The effects of age at correction of aortic coarctation and recurrent obstruction on adolescent patients: MRI evaluation of wall shear stress and pulse wave velocity.
Juffermans JF, Nederend I, van den Boogaard PJ, Ten Harkel ADJ, Hazekamp MG, Lamb HJ, Roest AAW, Westenberg JJM
Background: Coarctation patients before curative reconstruction are exposed to abnormal flow patterns which potentially could cause wall deterioration. This study evaluated the effect of age at correction on the pulse wave velocity (PWV) and peak wall shear stress (WSS) in adolescent patients with corrected coarctation. Effects of valve morphology and presence of reobstruction were also evaluated. Methods: Twenty-one patients aged 13.7 ± 2.6 years (mean ± standard deviation) were included (bicus...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
The American journal of medicine,
Volume 132, Issue 12, 20 3 2019, Pages 1466-1474.e4
Cognitive Function in Dementia-Free Subjects and Survival in Old Age: The PROSPER Study.
Rostamian S, de Haan S, van der Grond J, van Buchem MA, Ford I, Jukema JW, Sabayan B
Background: Impairment in domain-specific cognitive function is associated with the increased risk of mortality. We prospectively evaluated the association of executive function and memory with the risk of long-term mortality in dementia-free older subjects. Moreover, we investigated the role of structural brain abnormalities in this association. Methods: We included 547 dementia-free participants (mean age 78 years, 56.5% male) from the nested magnetic resonance imaging sub-study of the PROspec...
Abstract
Cited 28 times since 2019 (4.4 per year)
source: EuropePMC
Annals of the rheumatic diseases,
Volume 78, Issue 10, 19 3 2019, Pages 1339-1345
Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire.
Pollastro S, Klarenbeek PL, Doorenspleet ME, van Schaik BDC, Esveldt REE, Thurlings RM, Boumans MJH, Gerlag DM, Tak PP, Vos K, Baas F, van Kampen AHC, de Vries N
Objective: To gain more insight into the dynamics of lymphocyte depletion and develop new predictors of clinical response to rituximab in rheumatoid arthritis (RA). Methods: RNA-based next-generation sequencing was used to analyse the B cell receptor (BCR) repertoire in peripheral blood and synovial tissue samples collected from 24 seropositive patients with RA treated with rituximab. Clonal expansion, mutation load and clonal overlap were assessed in samples collected before, at week 4 and at w...
Abstract
Cited 8 times since 2019 (1.2 per year)
source: EuropePMC
Developmental science,
Volume 23, Issue 1, 18 3 2019, Pages e12869
Motion tracking of parents' infant- versus adult-directed actions reveals general and action-specific modulations.
van Schaik JE, Meyer M, van Ham CR, Hunnius S
Parents tend to modulate their movements when demonstrating actions to their infants. Thus far, these modulations have primarily been quantified by human raters and for entire interactions, thereby possibly overlooking the intricacy of such demonstrations. Using optical motion tracking, the precise modulations of parents' infant-directed actions were quantified and compared to adult-directed actions and between action types. Parents demonstrated four novel objects to their 14-month-old infa...
Abstract
Cited 11 times since 2019 (1.7 per year)
source: EuropePMC
International journal of clinical pharmacy,
Volume 41, Issue 4, 17 3 2019, Pages 963-971
Cost-effectiveness of a clinical medication review in vulnerable older patients at hospital discharge, a randomized controlled trial.
van der Heijden AAWA, de Bruijne MC, Nijpels G, Hugtenburg JG
Background Drug-related problems (DRP) following hospital discharge may cause morbidity, mortality and hospital re-admissions. It is unclear whether a clinical medication review (CMR) and counseling at discharge is a cost-effective method to reduce DRP. Objective To assess the effect of a CMR on health care utilization and to investigate whether CMR is a cost-effective method to reduce DRP in older polypharmacy patients discharged from hospital. Setting 24 community pharmacies in the Netherlands...
Abstract
Cited 15 times since 2019 (2.3 per year)
source: EuropePMC
PloS one,
Volume 14, Issue 6, 14 2 2019, Pages e0217582
Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury.
Pluijmert NJ, den Haan MC, van Zuylen VL, Steendijk P, de Boer HC, van Zonneveld AJ, Fibbe WE, Schalij MJ, Quax PHA, Atsma DE
Background: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolemia on cardiac function and remodeling were investigated up to eight weeks after myocardial ischemia-reperfusion (MI-R) injury which was induced in either normocholesterolemic (NC-MI) or hypercholester...
Abstract
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
Journal of cardiothoracic and vascular anesthesia,
Volume 33, Issue 12, 14 2 2019, Pages 3273-3280
Vasoplegia After Restrictive Mitral Annuloplasty for Functional Mitral Regurgitation in Patients With Heart Failure.
van Vessem ME, Petrus AHJ, Palmen M, Braun J, Schalij MJ, Klautz RJM, Beeres SLMA
Objectives: Patients undergoing heart failure surgery are at risk for developing postoperative vasoplegia. The aim of this study was to determine the incidence, survival, and predictors of vasoplegia in heart failure patients undergoing mitral valve repair for functional mitral regurgitation and to evaluate the effect of ischemic versus non-ischemic etiology. Design: Retrospective. Setting: University medical center, single institutional. Participants: Heart failure patients with functional mitr...
Abstract
Cited 13 times since 2019 (2 per year)
source: EuropePMC
American journal of primatology,
Volume 81, Issue 6, 13 2 2019, Pages e22996
Determining overweight and underweight with a new weight-for-height index in captive group-housed macaques.
Sterck EHM, Zijlmans DGM, de Vries H, van den Berg LM, van Schaik CP, Langermans JAM
Housing primates in naturalistic groups provides social benefits relative to solitary housing. However, food intake may vary across individuals, possibly resulting in overweight and underweight individuals. Information on relative adiposity (the amount of fat tissue relative to body weight) is needed to monitor overweight and underweight of group-housed individuals. However, the upper and lower relative adiposity boundaries are currently only known for macaques living solitarily in small cages....
Abstract
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 6, 13 2 2019, Pages 77
CD8+ T Cells Protect During Vein Graft Disease Development.
Simons KH, de Vries MR, Peters HAB, Jukema JW, Quax PHA, Arens R
Aims: Vein grafts are frequently used conduits for arterial reconstruction in patients with cardiovascular disease. Unfortunately, vein graft disease (VGD) causes diminished patency rates. Innate immune system components are known to contribute to VGD. However, the role of T cells has yet to be established. The purpose of this study was to investigate the role of T cells and T cell activation pathways via the T cell receptor (TCR), co-stimulation and bystander effect in VGD. Methods and results:...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 85, Issue 8, 12 2 2019, Pages 1852-1854
Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose.
Berger FA, Mulder MB, Ten Bosch-Dijksman W, van Schaik RHN, Coenen S, de Winter BCM
Tacrolimus (Tac) is well established as main immunosuppressant in most immunosuppressive regimens in solid organ transplantation. Due to the narrow therapeutic window, pre dose Tac levels (C0) are monitored in all patients receiving Tac to reach optimal therapeutic levels. Tac is metabolized in the liver and intestine by the cytochrome P450 3A (CYP3A) isoforms CYP3A4 and CYP3A5. We present a case of an African American woman who underwent a liver transplantation in which adequate Tac levels were...
Abstract
Cited 32 times since 2019 (5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 2 Pt 1, 12 2 2019, Pages 425-434
Application of Low Tube Potentials in CCTA: Results From the PROTECTION VI Study.
Stocker TJ, Leipsic J, Hadamitzky M, Chen MY, Rubinshtein R, Deseive S, Heckner M, Bax JJ, Kitagawa K, Marques H, Schmermund A, Silva C, Mahmarian J, Kang JW, Grove EL, Lesser J, Massberg S, Hausleiter J
Objectives: The aim of this study was to assess the use of low tube potentials for coronary computed tomography angiography (CCTA) in worldwide clinical practice and its influence on radiation exposure, contrast agent volume, and image quality. Background: CCTA is frequently used in clinical practice. Lowering of tube potential is a potent method to reduce radiation exposure and to economize contrast agent volume. Methods: CCTAs of 4,006 patients from 61 international study sites were analyzed r...
Abstract
Cited 57 times since 2019 (8.8 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 2 Pt 2, 12 2 2019, Pages 577-585
Prognostic Value of Global Longitudinal Strain and Etiology After Surgery for Primary Mitral Regurgitation.
Hiemstra YL, Tomsic A, van Wijngaarden SE, Palmen M, Klautz RJM, Bax JJ, Delgado V, Ajmone Marsan N
Objectives: This study sought to investigate whether left ventricular (LV) global longitudinal strain (GLS) is associated with long-term outcome after mitral valve (MV) surgery for primary mitral regurgitation (MR) and assess the differences in outcome according to MR etiology: Barlow's disease (BD), fibroelastic deficiency (FED), and forme fruste (FF). Background: Appropriate timing of MV surgery for primary MR is still challenging and may differ according to the etiology. In these patient...
Abstract
Cited 111 times since 2019 (17.2 per year)
source: EuropePMC
Circulation,
Volume 140, Issue 10, 12 2 2019, Pages 836-845
Prognostic Implications of Right Ventricular Remodeling and Function in Patients With Significant Secondary Tricuspid Regurgitation.
Dietz MF, Prihadi EA, van der Bijl P, Goedemans L, Mertens BJA, Gursoy E, van Genderen OS, Ajmone Marsan N, Delgado V, Bax JJ
Background: In patients with significant (moderate and severe) tricuspid regurgitation (TR), the decision to intervene is influenced by right ventricular (RV) size and function. RV remodeling in significant secondary TR has been underexplored. The aim of this study was to characterize RV remodeling in patients with significant secondary TR and to investigate its prognostic implications. Methods: RV remodeling was characterized by transthoracic echocardiography in 1292 patients with significant s...
Abstract
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
BMC psychiatry,
Volume 19, Issue 1, 11 2 2019, Pages 179
The decision tool unipolar depression (DTUD): a new measure to facilitate the early identification of patients with major depressive disorder in need of highly specialized care.
van Krugten FCW, Goorden M, van Balkom AJLM, van Oppen P, Ruhé HG, van Schaik DJF, Brouwer WBF, Hakkaart-van Roijen L, Decision Tool Unipolar Depression Consortium
Background: Selection of the optimal initial treatment in patients with major depressive disorder (MDD) in need of highly specialized care has the potential to benefit treatment outcomes and cost-effectiveness of treatment strategies. However, to date, there is a paucity of measures that could guide the selection of the initial treatment, in particular to indicate which patients with MDD are in need of highly specialized care. Recognizing this gap, this paper reports on the development and psych...
Abstract
Cited 13 times since 2019 (2 per year)
source: EuropePMC
Biology open,
Volume 8, Issue 6, 10 2 2019, Pages bio039263
Influence of arm swing on cost of transport during walking.
de Graaf ML, Hubert J, Houdijk H, Bruijn SM
Normal arm swing plays a role in decreasing the cost of transport during walking. However, whether excessive arm swing can reduce the cost of transport even further is unknown. Therefore, we tested the effects of normal and exaggerated arm swing on the cost of transport in the current study. Healthy participants (n=12) walked on a treadmill (1.25 m/s) in seven trials with different arm swing amplitudes (in-phase, passive restricted, active restricted, normal, three gradations of extra arm swing)...
Abstract
Cited 8 times since 2019 (1.2 per year)
source: EuropePMC
Seizure,
Volume 71, 10 2 2019, Pages 50-55
The effect of early midazolam infusion on the duration of pediatric status epilepticus patients.
Ulusoy E, Duman M, Türker HD, Çağlar A, Er A, Akgül F, Çitlenbik H, Öztürk A, Yılmaz D
Purpose: Status epilepticus is one of the most common neurological emergencies in pediatric emergency departments. Although there are different approaches to treatment in the literature, early control of seizure activity is the most important factor determining prognosis. The purpose of this study was to evaluate the effect of early midazolam infusion on seizure duration. Method: This retrospective study included 150 episodes of 135 patients aged one month to 18 years old with status epilepticus...
Abstract
Cited 45 times since 2019 (7 per year)
source: EuropePMC
Epigenetics & chromatin,
Volume 12, Issue 1, 6 1 2019, Pages 34
Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites.
Dekkers KF, Neele AE, Jukema JW, Heijmans BT, de Winther MPJ
Background: Macrophages and their precursors monocytes play a key role in inflammation and chronic inflammatory disorders. Monocyte-to-macrophage differentiation and activation programs are accompanied by significant epigenetic remodeling where DNA methylation associates with cell identity. Here we show that DNA methylation changes characteristic for monocyte-to-macrophage differentiation occur at transcription factor binding sites, and, in contrast to what was previously described, are generall...
Abstract
Cited 95 times since 2019 (14.7 per year)
source: EuropePMC
The lancet. Gastroenterology & hepatology,
Volume 4, Issue 8, 6 1 2019, Pages 599-610
Hartmann's procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial.
Lambrichts DPV, Vennix S, Musters GD, Mulder IM, Swank HA, Hoofwijk AGM, Belgers EHJ, Stockmann HBAC, Eijsbouts QAJ, Gerhards MF, van Wagensveld BA, van Geloven AAW, Crolla RMPH, Nienhuijs SW, Govaert MJPM, di Saverio S, D'Hoore AJL, Consten ECJ, van Grevenstein WMU, Pierik REGJM, Kruyt PM, van der Hoeven JAB, Steup WH, Catena F, Konsten JLM, Vermeulen J, van Dieren S, Bemelman WA, Lange JF, LADIES trial collaborators
Background: Previous studies have suggested that sigmoidectomy with primary anastomosis is superior to Hartmann's procedure. The likelihood of stoma reversal after primary anastomosis has been reported to be higher and reversal seems to be associated with lower morbidity and mortality. Although promising, results from these previous studies remain uncertain because of potential selection bias. Therefore, this study aimed to assess outcomes after Hartmann's procedure versus sigmoidectom...
Abstract
