9543 results
Cited 13 times since 2018 (1.8 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 7 Pt 1, 12 2 2018, Pages 1188-1198
Effect of Early Metoprolol During ST-Segment Elevation Myocardial Infarction on Left Ventricular Strain: Feature-Tracking Cardiovascular Magnetic Resonance Substudy From the METOCARD-CNIC Trial.
Podlesnikar T, Pizarro G, Fernández-Jiménez R, Montero-Cabezas JM, Sánchez-González J, Bucciarelli-Ducci C, Ajmone Marsan N, Fras Z, Bax JJ, Fuster V, Ibáñez B, Delgado V
Objectives: This study sought to evaluate the effect of early intravenous metoprolol on left ventricular (LV) strain assessed with feature-tracking cardiovascular magnetic resonance (CMR). Background: Early intravenous metoprolol before primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) portends better outcomes in the METOCARD-CNIC (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction) trial. Methods: A total of 197 pa...
Abstract
Cited 9 times since 2018 (1.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 274, 12 2 2018, Pages 113-116
Aortic dissection and prophylactic surgery in congenital heart disease.
Kuijpers JM, Koolbergen DR, Groenink M, Boekholdt SM, Meijboom FJ, Jongbloed MRM, Hoendermis ES, Duijnhouwer AL, Mulder BJM, Bouma BJ
Background: Proximal aortic dilatation in certain congenital heart diseases (CHD) prompts concerns about dissection and consideration of prophylactic surgery. To evaluate contemporary prophylactic practice, we determined incidence of aortic dissection and prophylactic surgery in aortopathy-associated CHD, compared to Marfan syndrom (MFS) and controls. Methods and results: We followed patients from the CONCOR adult CHD registry (2002-2015), with a native proximal aorta and aortopathy-associated C...
Abstract
Cited 34 times since 2018 (4.7 per year)
source: EuropePMC
NPJ genomic medicine,
Volume 3, 11 2 2018, Pages 26
User considerations in assessing pharmacogenomic tests and their clinical support tools.
Mukerjee G, Huston A, Kabakchiev B, Piquette-Miller M, van Schaik R, Dorfman R
Pharmacogenomic (PGx) testing is gaining recognition from physicians, pharmacists and patients as a tool for evidence-based medication management. However, seemingly similar PGx testing panels (and PGx-based decision support tools) can diverge in their technological specifications, as well as the genetic factors that determine test specificity and sensitivity, and hence offer different values for users. Reluctance to embrace PGx testing is often the result of unfamiliarity with PGx technology, a...
Abstract
Cited 52 times since 2018 (7.2 per year)
source: EuropePMC
Journal of internal medicine,
Volume 285, Issue 1, 7 1 2018, Pages 59-74
Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels.
de Vries MR, Parma L, Peters HAB, Schepers A, Hamming JF, Jukema JW, Goumans MJTH, Guo L, Finn AV, Virmani R, Ozaki CK, Quax PHA
Background: Plaque angiogenesis is associated with atherosclerotic lesion growth, plaque instability and negative clinical outcome. Plaque angiogenesis is a natural occurring process to fulfil the increasing demand of oxygen and nourishment of the vessel wall. However, inadequate formed, immature plaque neovessels are leaky and cause intraplaque haemorrhage. Objective: Blockade of VEGFR2 normalizes the unbridled process of plaque neovessel formation and induces maturation of nascent vessels resu...
Abstract
Cited 29 times since 2018 (4 per year)
source: EuropePMC
Molecular genetics and metabolism,
Volume 125, Issue 3, 5 1 2018, Pages 205-216
Development and clinical consequences of white matter lesions in Fabry disease: a systematic review.
Körver S, Vergouwe M, Hollak CEM, van Schaik IN, Langeveld M
Background: Fabry disease (FD) is a rare lysosomal storage disorder that might result in, amongst other complications, early stroke and white matter lesions (WMLs). More insight in WMLs in FD could clarify the role of WMLs in the disease presentation and prognosis in FD. In this systematic review we assessed the prevalence, severity, location and course of WMLs in FD. We also systematically reviewed the evidence on the relation between WMLs, disease characteristics and clinical parameters. Metho...
Abstract
Cited 103 times since 2018 (14.2 per year)
source: EuropePMC
JAMA cardiology,
Volume 3, Issue 9, 1 1 2018, Pages 839-847
Association of Left Ventricular Global Longitudinal Strain With Asymptomatic Severe Aortic Stenosis: Natural Course and Prognostic Value.
Vollema EM, Sugimoto T, Shen M, Tastet L, Ng ACT, Abou R, Marsan NA, Mertens B, Dulgheru R, Lancellotti P, Clavel MA, Pibarot P, Genereux P, Leon MB, Delgado V, Bax JJ
Importance: The optimal timing to operate in patients with asymptomatic severe aortic stenosis (AS) remains controversial. Left ventricular global longitudinal strain (LV GLS) may help to identify patients who might benefit from undergoing earlier aortic valve replacement. Objective: To investigate the prevalence of impaired LV GLS, the natural course of LV GLS, and its prognostic implications in patients with asymptomatic severe AS with preserved left ventricular ejection fraction (LVEF). Desig...
Abstract
Cited 38 times since 2018 (5.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 26, Issue 9, 1 1 2018, Pages 417-421
2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: comments from the Dutch ACS working group.
Arslan F, Bongartz L, Ten Berg JM, Jukema JW, Appelman Y, Liem AH, de Winter RJ, van 't Hof AWJ, Damman P
On behalf of the Dutch ACS working group, we discuss the most important changes in recommendations in the 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation relevant for both the general and interventional cardiologist.
Abstract
Cited 320 times since 2018 (44.3 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 35, 1 1 2018, Pages 3322-3330
The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability.
Knuuti J, Ballo H, Juarez-Orozco LE, Saraste A, Kolh P, Rutjes AWS, Jüni P, Windecker S, Bax JJ, Wijns W
Aims: To determine the ranges of pre-test probability (PTP) of coronary artery disease (CAD) in which stress electrocardiogram (ECG), stress echocardiography, coronary computed tomography angiography (CCTA), single-photon emission computed tomography (SPECT), positron emission tomography (PET), and cardiac magnetic resonance (CMR) can reclassify patients into a post-test probability that defines (>85%) or excludes (100 patients with stable CAD that utilized either ICA or ICA with FFR measurem...
Abstract
Cited 14 times since 2018 (1.9 per year)
source: EuropePMC
Current opinion in cardiology,
Volume 33, Issue 5, 1 1 2018, Pages 470-478
Application of left ventricular strain in patients with aortic and mitral valve disease.
Ng ACT, Delgado V, Bax JJ
Purpose of review: Left ventricular (LV) global longitudinal strain (GLS) is widely recognized as a more sensitive measure of LV systolic function compared with LV ejection fraction (LVEF). In addition, the measurement of LVGLS is more reproducible than two-dimensional LVEF. Current guidelines for diagnosis and treatment of valvular heart disease include LVEF as one of the parameters to take into consideration in the clinical decision-making. However, a large body of evidence is showing that LVG...
Abstract
JACC. Clinical electrophysiology,
Volume 4, Issue 9, 1 1 2018, Pages 1211-1213
Imaging to Evaluate the Substrate Underlying Sudden Cardiac Death.
Bax JJ, Delgado V
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Marine pollution bulletin,
Volume 134, 1 1 2018, Pages 1-4
Towards recognition of seagrasses, and their sustainable management.
Keulen MV, Nordlund LM, Cullen-Unsworth LC
Abstract
JACC. Clinical electrophysiology,
Volume 4, Issue 9, 1 1 2018, Pages 1163-1165
Characterization of Septal Scars in Nonischemic Left Ventricular Cardiomyopathy by Cardiac Magnetic Resonance Imaging Versus Electroanatomical Mapping: Superior, Inferior, or Complementary?
Zeppenfeld K, Piers SRD
Abstract
Cited 121 times since 2018 (16.7 per year)
source: EuropePMC
JAMA cardiology,
Volume 3, Issue 9, 1 1 2018, Pages 806-814
Effect of Infusion of High-Density Lipoprotein Mimetic Containing Recombinant Apolipoprotein A-I Milano on Coronary Disease in Patients With an Acute Coronary Syndrome in the MILANO-PILOT Trial: A Randomized Clinical Trial.
Nicholls SJ, Puri R, Ballantyne CM, Jukema JW, Kastelein JJP, Koenig W, Wright RS, Kallend D, Wijngaard P, Borgman M, Wolski K, Nissen SE
Importance: Infusing a high-density lipoprotein mimetic containing apolipoprotein A-I Milano demonstrated potential atheroma regression in patients following an acute coronary syndrome. To our knowledge, the effect of infusing a new mimetic preparation (MDCO-216) with contemporary statin therapy is unknown. Objective: To determine the effect of infusing MDCO-216 on coronary atherosclerosis progression. Design, setting, and participants: This double-blind, randomized clinical trial conducted in 2...
Abstract
Cited 18 times since 2018 (2.5 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 54, Issue 3, 1 1 2018, Pages 585-592
Aortopexy for the treatment of tracheobronchomalacia in 100 children: a 10-year single-centre experience.
Rijnberg FM, Butler CR, Bieli C, Kumar S, Nouraei R, Asto J, McKavanagh E, de Coppi P, Muthialu N, Elliott MJ, Hewitt RJ
Objectives: Our study describes and analyses the results from aortopexy for the treatment of airway malacia in children. Methods: Demographic data, characteristics and preoperative, operative and outcome details, including the need for reintervention, were collected for children undergoing aortopexy between 2006 and 2016. Results: One hundred patients [median age 8.2 months, interquartile range (IQR) 3.3-26.0 months] underwent aortopexy. Sixty-four (64%) patients had tracheomalacia (TM) only, 24...
Abstract
Cited 3 times since 2018 (0.4 per year)
source: EuropePMC
International journal of cardiology,
Volume 274, 1 1 2018, Pages 331-336
Borderline Q-waves in individuals without overt cardiovascular disease: Relations with adiposity, subclinical atherosclerosis and vascular stiffness.
Elffers TW, Trompet S, de Mutsert R, Maan AC, Lamb HJ, Macfarlane PW, Rosendaal FR, Jukema JW
Background: Characteristics and risk factors associated with electrocardiographic borderline Q-waves are not fully elucidated, especially in individuals without overt cardiovascular disease (CVD). Also, the relation of isolated and non-isolated borderline Q-waves with subclinical atherosclerosis and vascular stiffness is unknown. Methods and results: We included 5746 Netherlands Epidemiology of Obesity study participants without overt CVD. Participants were divided in three groups: no Q-waves (9...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 19, Issue 9, 1 1 2018, Pages 975-976
The effect of blood pressure on left atrial size and function assessed by 3-dimensional echocardiography.
Abou R, Delgado V
Abstract
Cited 22 times since 2018 (3 per year)
source: EuropePMC
Current biology : CB,
Volume 28, Issue 17, 30 5 2018, Pages 2800-2805.e4
Payoff- and Sex-Biased Social Learning Interact in a Wild Primate Population.
Bono AEJ, Whiten A, van Schaik C, Krützen M, Eichenberger F, Schnider A, van de Waal E
Social learning in animals is now well documented, but few studies have determined the contexts shaping when social learning is deployed. Theoretical studies predict copying of conspecifics gaining higher payoffs [1-4], a bias demonstrated in primates only in captivity [5]. In the wild, research has shown selective attention toward the philopatric sex, a group's stable core [6]. Here, we report the first rigorous experimental test of the existence of a payoff bias in wild primates and its i...
Abstract
Cited 32 times since 2018 (4.4 per year)
source: EuropePMC
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,
Volume 124, 30 5 2018, Pages 217-227
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants.
van Groen BD, van de Steeg E, Mooij MG, van Lipzig MMH, de Koning BAE, Verdijk RM, Wortelboer HM, Gaedigk R, Bi C, Leeder JS, van Schaik RHN, van Rosmalen J, Tibboel D, Vaes WH, de Wildt SN
Background: Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples. Methods: Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3, NTCP, OCT1, OATP1B1, OATP1B3, OATP2B1 and ATP1A1 were quantified with LC-MS/MS in isolated crude membrane fractions of snap-frozen post-mortem fetal an...
Abstract
Cited 36 times since 2018 (5 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 4, Issue 9, 29 5 2018, Pages 1123-1140
Ventricular Tachycardia Ablation in Nonischemic Cardiomyopathy.
Zeppenfeld K
Catheter ablation is being increasingly performed as adjunctive treatment to prevent recurrent implantable cardioverter-defibrillator therapies in patients with nonischemic cardiomyopathy and ventricular tachycardia (VT). In the context of VT ablation, nonischemic cardiomyopathy usually refers to dilated cardiomyopathy (DCM) as one morphological phenotype. Over the past decades, progress has been made to better characterize distinct subtypes and to differentiate between causes of DCM, which has...
Abstract
Cited 182 times since 2018 (25.1 per year)
source: EuropePMC
BMJ (Clinical research ed.),
Volume 362, 29 5 2018, Pages k3225
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.
Trajanoska K, Morris JA, Oei L, Zheng HF, Evans DM, Kiel DP, Ohlsson C, Richards JB, Rivadeneira F, GEFOS/GENOMOS consortium and the 23andMe research team
Objectives: To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design: Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting: 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants: A discovery set of 37 857 fracture cases and 227 116 controls; with replication in up to 147 200 fracture...
Abstract
