9543 results
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
PloS one,
Volume 13, Issue 4, 26 4 2018, Pages e0196448
Evaluating the relationship between lesion burden and aging among the skeletons of an 18th-19th century London cemetery using osteological and radiological analysis.
van Schaik K, Eisenberg R, Bekvalac J, Rühli F
Study of disease in the past can help illuminate patterns of human health, disease, and aging in the present. As average human life expectancy and incidence of chronic disease have increased in the last century, efforts to understand this epidemiologic shift have led to more investigation of healthy aging. Using osteological and radiological methods of analysis, this study examined 212 mostly nineteenth century adult skeletons from the crypt of St. Bride's in London, in order to investigate...
Abstract
Cited 47 times since 2018 (6.2 per year)
source: EuropePMC
The Canadian journal of cardiology,
Volume 34, Issue 8, 25 4 2018, Pages 1069-1078
Prognostic Value of Right Ventricular Strain Using Speckle-Tracking Echocardiography in Pulmonary Hypertension: A Systematic Review and Meta-analysis.
Shukla M, Park JH, Thomas JD, Delgado V, Bax JJ, Kane GC, Howlett JG, White JA, Fine NM
Background: Right ventricular (RV) strain imaging using speckle-tracking echocardiography (STE) is a quantitative method of assessing RV systolic function that has shown prognostic utility in patients with pulmonary hypertension (PH). However, its prognostic value for a large and mixed PH population remains poorly defined. Methods: A systematic review and meta-analysis was performed using the MedLine, Embase, and Cochrane Library databases for publications reporting the prognostic value of RV st...
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
The American journal of pathology,
Volume 188, Issue 7, 22 4 2018, Pages 1524-1529
Leukocyte Dynamics during the Evolution of Human Coronary Atherosclerosis: Conclusions from a Sevenfold, Chromogen-Based, Immunohistochemical Evaluation.
Zuiderwijk M, Geerts M, van Rhijn CJ, van den Bogaerdt A, Hamming JF, van Dijk RA, Lindeman JH
Atherosclerosis is a complex process with strong inflammatory component. We developed a straightforward sevenfold staining protocol for simultaneous assessment of dominant leukocyte classes, vascularization, and expression of the putative foam cell maker CD36. The method was applied on human coronaries covering the full spectrum of atherosclerotic disease. Results confirm the progressive association of macrophages and T cells with the process and a global presence of mast cells. B cells are excl...
Abstract
Cited 28 times since 2018 (3.7 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 156, Issue 4, 18 3 2018, Pages 1368-1377.e5
One-year outcomes associated with a novel stented bovine pericardial aortic bioprosthesis.
Sabik JF, Rao V, Lange R, Kappetein AP, Dagenais F, Labrousse L, Bapat V, Moront M, Weissman NJ, Patel HJ, Reardon MJ, Asch FM, Zeng C, Klautz RJM, PERIGON Investigators
Objectives: The study objectives were to evaluate the safety, effectiveness, and hemodynamic performance of a new stented bovine pericardial aortic valve. Methods: This trial enrolled patients with symptomatic moderate or severe aortic stenosis or chronic, severe aortic regurgitation. We assessed death, valve-related adverse events, functional recovery, and hemodynamic performance at discharge, 3 to 6 months, and 1 year, as required by the US Food and Drug Administration for regulatory approval....
Abstract
Cited 4 times since 2018 (0.5 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 26, Issue 5, 12 2 2018, Pages 1731-1733
Chronic total occlusion without collateral blood flow does not exclude myocardial viability and subsequent recovery after revascularization.
Bax JJ, Delgado V
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Anatolian journal of cardiology,
Volume 19, Issue 5, 10 2 2018, Pages 303-310
Increased microvolt T-wave alternans in children and adolescents with Eisenmenger syndrome.
Karpuz D, Hallıoğlu O, Yılmaz DÇ
Objective: To determine the values of microvolt T-wave alternans (MTWA) in children and adolescents with Eisenmenger syndrome (ES) and controls. Methods: Thirteen were included in the study. After analyzing the 24-h ECG recordings, MTWA was considered using three leads (V5, V1, and aVF). Right heart catheterization and 6-minute walk test (6-MWD) were applied to the patients and pro-brain natriuretic peptide levels were assessed; echocardiographic parameters were obtained from both the groups and...
Abstract
Cited 12 times since 2018 (1.6 per year)
source: EuropePMC
Journal of cellular biochemistry,
Volume 119, Issue 7, 10 2 2018, Pages 6146-6153
Cardiomyogenic differentiation of human adipose-derived mesenchymal stem cells transduced with Tbx20-encoding lentiviral vectors.
Neshati V, Mollazadeh S, Fazly Bazzaz BS, de Vries AA, Mojarrad M, Naderi-Meshkin H, Neshati Z, Kerachian MA
Ischemic heart disease often results in myocardial infarction and is the leading cause of mortality and morbidity worldwide. Improvement in the function of infarcted myocardium is a main purpose of cardiac regenerative medicine. One possible way to reach this goal is via stem cell therapy. Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types but display limited cardiomyogenic differentiation potential. Members of the T-box family of tran...
Abstract
Cited 17 times since 2018 (2.2 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 12, 10 2 2018, Pages 213
An FPGA-Based Massively Parallel Neuromorphic Cortex Simulator.
Wang RM, Thakur CS, van Schaik A
This paper presents a massively parallel and scalable neuromorphic cortex simulator designed for simulating large and structurally connected spiking neural networks, such as complex models of various areas of the cortex. The main novelty of this work is the abstraction of a neuromorphic architecture into clusters represented by minicolumns and hypercolumns, analogously to the fundamental structural units observed in neurobiology. Without this approach, simulating large-scale fully connected netw...
Abstract
Cited 8 times since 2018 (1 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 12, 10 2 2018, Pages 198
A FPGA Implementation of the CAR-FAC Cochlear Model.
Xu Y, Thakur CS, Singh RK, Hamilton TJ, Wang RM, van Schaik A
This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC) cochlear model. The CAR part simulates the basilar membrane's (BM) response to sound. The FAC part models the outer hair cell (OHC), the inner hair cell (IHC), and the medial olivocochlear efferent system functions. The FAC feeds back to the CAR by moving the poles and zeros of the CAR resonators automatically. We have implemented a 70-section, 44.1 kHz sampling rate C...
Abstract
Cited 17 times since 2018 (2.2 per year)
source: EuropePMC
European radiology,
Volume 28, Issue 9, 6 1 2018, Pages 4027-4035
High spatial resolution free-breathing 3D late gadolinium enhancement cardiac magnetic resonance imaging in ischaemic and non-ischaemic cardiomyopathy: quantitative assessment of scar mass and image quality.
Bizino MB, Tao Q, Amersfoort J, Siebelink HJ, van den Bogaard PJ, van der Geest RJ, Lamb HJ
Purpose: To compare breath-hold (BH) with navigated free-breathing (FB) 3D late gadolinium enhancement cardiac MRI (LGE-CMR) MATERIALS AND METHODS: Fifty-one patients were retrospectively included (34 ischaemic cardiomyopathy, 14 non-ischaemic cardiomyopathy, three discarded). BH and FB 3D phase sensitive inversion recovery sequences were performed at 3T. FB datasets were reformatted into normal resolution (FB-NR, 1.46x1.46x10mm) and high resolution (FB-HR, isotropic 0.91-mm voxels). Scar mass,...
Abstract
Cited 134 times since 2018 (17.5 per year)
source: EuropePMC
The Journal of clinical investigation,
Volume 128, Issue 5, 3 1 2018, Pages 1837-1851
Mycobacterial growth inhibition is associated with trained innate immunity.
Joosten SA, van Meijgaarden KE, Arend SM, Prins C, Oftung F, Korsvold GE, Kik SV, Arts RJ, van Crevel R, Netea MG, Ottenhoff TH
The lack of defined correlates of protection hampers development of vaccines against tuberculosis (TB). In vitro mycobacterial outgrowth assays are thought to better capture the complexity of the human host/Mycobacterium tuberculosis (Mtb) interaction. Here, we used a mycobacterial growth inhibition assay (MGIA) based on peripheral blood mononuclear cells to investigate the capacity to control outgrowth of bacille Calmette-Guérin (BCG). Interestingly, strong control of BCG outgrowth was observed...
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 12, Issue 3, 3 1 2018, Pages 212-219
Diagnostic accuracy of semi-automatic quantitative metrics as an alternative to expert reading of CT myocardial perfusion in the CORE320 study.
Ostovaneh MR, Vavere AL, Mehra VC, Kofoed KF, Matheson MB, Arbab-Zadeh A, Fujisawa Y, Schuijf JD, Rochitte CE, Scholte AJ, Kitagawa K, Dewey M, Cox C, DiCarli MF, George RT, Lima JAC
Aims: To determine the diagnostic accuracy of semi-automatic quantitative metrics compared to expert reading for interpretation of computed tomography perfusion (CTP) imaging. Methods: The CORE320 multicenter diagnostic accuracy clinical study enrolled patients between 45 and 85 years of age who were clinically referred for invasive coronary angiography (ICA). Computed tomography angiography (CTA), CTP, single photon emission computed tomography (SPECT), and ICA images were interpreted manually...
Abstract
Cited 20 times since 2018 (2.6 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 106, Issue 2, 3 1 2018, Pages 412-420
National Comparison of Hospital Performances in Lung Cancer Surgery: The Role of Case Mix Adjustment.
Beck N, Hoeijmakers F, van der Willik EM, Heineman DJ, Braun J, Tollenaar RAEM, Schreurs WH, Wouters MWJM
Background: When comparing hospitals on outcome indicators, proper adjustment for case mix (a combination of patient and disease characteristics) is indispensable. This study examines the need for case mix adjustment in evaluating hospital outcomes for non-small cell lung cancer surgery. Methods: Data from the Dutch Lung Cancer Audit for Surgery were used to validate factors associated with postoperative 30-day mortality and complicated course with multivariable logistic regression models. Betwe...
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 71, Issue 15, 1 1 2018, Pages 1661-1662
Machine Learning for Electrocardiographic Diagnosis of Left Ventricular Early Diastolic Dysfunction.
Bax JJ, van der Bijl P, Delgado V
Abstract
Cited 14 times since 2018 (1.8 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 11, Issue 4, 1 1 2018, Pages e007117
Cardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study.
Bonios MJ, Koliopoulou A, Wever-Pinzon O, Taleb I, Stehlik J, Xu W, Wever-Pinzon J, Catino A, Kfoury AG, Horne BD, Nativi-Nicolau J, Adamopoulos SN, Fang JC, Selzman CH, Bax JJ, Drakos SG
Background: Impaired qualitative and quantitative left ventricular (LV) rotational mechanics predict cardiac remodeling progression and prognosis after myocardial infarction. We investigated whether cardiac rotational mechanics can predict cardiac recovery in chronic advanced cardiomyopathy patients. Methods and results: Sixty-three patients with advanced and chronic dilated cardiomyopathy undergoing implantation of LV assist device (LVAD) were prospectively investigated using speckle tracking e...
Abstract
Cited 124 times since 2018 (16.2 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 14, 1 1 2018, Pages 1131-1143
2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia.
Landmesser U, Chapman MJ, Stock JK, Amarenco P, Belch JJF, Borén J, Farnier M, Ference BA, Gielen S, Graham I, Grobbee DE, Hovingh GK, Lüscher TF, Piepoli MF, Ray KK, Ray KK, Stroes ES, Wiklund O, Windecker S, Zamorano JL, Pinto F, Tokgözoglu L, Bax JJ, Catapano AL
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 26, Issue 4, 1 1 2018, Pages 566-572
Outcome reporting for surgical treatment of degenerative mitral valve disease: a systematic review and critical appraisal.
Tomšic A, Arabkhani B, Schoones JW, van Brakel TJ, Takkenberg JJM, Palmen M, Klautz RJM
Objectives: Standardized outcome reporting is of critical importance for performance monitoring, improvement of existing techniques and introduction of novel technologies. Whether outcome reporting for surgical treatment of degenerative mitral valve disease complies with the guidelines has not been assessed to date. Methods: A systematic review of PubMed, EMBASE, Web of Science and the Cochrane Library was conducted for articles published between 1 January 2009 and 7 March 2016. Inclusion criter...
Abstract
Cited 41 times since 2018 (5.4 per year)
source: EuropePMC
Endocrine reviews,
Volume 39, Issue 2, 1 1 2018, Pages 154-191
Diagnostic Utility of Molecular and Imaging Biomarkers in Cytological Indeterminate Thyroid Nodules.
de Koster EJ, de Geus-Oei LF, Dekkers OM, van Engen-van Grunsven I, Hamming J, Corssmit EPM, Morreau H, Schepers A, Smit J, Oyen WJG, Vriens D
Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned benign and malignant lesions, which are particularly difficult to differentiate on cytology alone. As ~25% of these nodules harbor malignancy, diagnostic hemithyroidectomy is still custom. However, advanced preoperative diagnostics are rapidly evolving.This review provides an overview of additional molecular and imaging diagnostics for indeterminate thyroid nodules in a preoperative clinical setting, includi...
Abstract
Cited 2 times since 2018 (0.3 per year)
source: EuropePMC
Journal of hypertension,
Volume 36, Issue 4, 1 1 2018, Pages 773-778
Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history.
Wijsman LW, Muller M, de Craen AJM, Jukema JW, Westendorp RGJ, Mooijaart SP
Background: In older age, a low DBP has been associated with increased risk of cardiovascular events, especially in frail older people. We tested the hypothesis that low DBP is associated with a high risk of cardiovascular events in people with a previous history of cardiovascular disease, as a proxy of vascular impairment. Methods: We included 5804 participants (mean age 75 years) from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) who as part of the trial were intensivel...
Abstract
Cited 12 times since 2018 (1.6 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 26, Issue 4, 1 1 2018, Pages 610-616
Early and late results of surgical treatment for isolated active native mitral valve infective endocarditis.
Tomšic A, Versteegh MIM, Ajmone Marsan N, van Brakel TJ, Klautz RJM, Palmen M
Objectives: Native mitral valve infective endocarditis (IE) is a complicated disease with high mortality and morbidity rates. Mitral valve repair (MVRep) is feasible when limited valve destruction is present. However, recurrent valve dysfunction and reintervention are common. Methods: Between January 2000 and March 2016, 83 patients underwent surgery for isolated active native mitral valve IE. We applied an early surgery, MVRep-oriented approach with progressive utilization of patch techniques t...
Abstract
