7971 results
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese,
6 1 2024, Pages S1109-9666(24)00139-8
Right ventricular-pulmonary arterial coupling in patients with first acute myocardial infarction: an emerging post-revascularization triage tool.
Anastasiou V, Daios S, Moysidis DV, Liatsos AC, Papazoglou AS, Didagelos M, Savopoulos C, Bax JJ, Ziakas A, Kamperidis V
Background: The tricuspid annular plane systolic excursion/pulmonary artery systolic pressure (TAPSE/PASP) ratio is a non-invasive surrogate for right ventricular-pulmonary arterial (RV-PA) coupling, studied in chronic RV pressure overload syndromes. However, its prognostic utility in patients with acute myocardial infarction (AMI), which may cause acute RV pressure overload, remains unexplored. Objective: This study aimed to determine predictors of RV-PA uncoupling in patients with first AMI an...
Abstract
Cited 7 times since 2024 (7.8 per year)
source: EuropePMC
Journal of clinical lipidology,
Volume 18, Issue 5, 6 1 2024, Pages e685-e700
Addressing residual risk beyond statin therapy: New targets in the management of dyslipidaemias-A report from the European Society of Cardiology Cardiovascular Round Table.
Mach F, Visseren FLJ, Cater NB, Salhi N, Soronen J, Ray KK, Delgado V, Jukema JW, Laufs U, Zamorano JL, Ros E, Plat J, Gesztes AG, Tokgozoglu L, Packard C, Libby P
Cardiovascular (CV) disease is the most common cause of death in Europe. Despite proven benefits, use of lipid-lowering therapy remains suboptimal. Treatment goals are often not achieved, even in patients at high risk with atherosclerotic CV disease (ASCVD). The occurrence of CV events in patients on lipid-lowering drugs is defined as "residual risk", and can result from inadequate control of plasma lipids or blood pressure, inflammation, diabetes, and environmental hazards. Assessment...
Abstract
Diabetes research and clinical practice,
Volume 214, 6 1 2024, Pages 111772
The impact of diabetes mellitus on foot perfusion measured by ICG NIR fluorescence imaging.
Koning S, van Kersen J, Tange FP, Kruiswijk MW, Peul RC, van Schaik J, Schepers A, Vahrmeijer AL, Hamming JF, van den Hoven P, van der Vorst JR
Introduction: Diabetes Mellitus (DM) is a common chronic disease, affecting 435 million people globally. Impaired vasculature in DM patients leads to complications like lower extremity arterial disease (LEAD) and foot ulcers, often resulting in amputations. DM causes additional peripheral neuropathy leading to multifactorial wound problems. Current diagnostics often deem unreliable, but Near-Infrared Fluorescence with Indocyanine Green (ICG NIR) can be used to assess the foot perfusion. Therefor...
Abstract
Journal of clinical medicine,
Volume 13, Issue 13, 5 1 2024, Pages 3945
Changes in Global Longitudinal Strain after TAVI: Additional Prognostic Value over Cardiac Damage in Patients with Severe Aortic Stenosis.
Myagmardorj R, Fortuni F, Galloo X, Nabeta T, Meucci MC, Butcher SC, van der Kley F, Bax JJ, Ajmone Marsan N
Background: Previous studies demonstrated the prognostic value of baseline cardiac damage staging as well as left ventricular global longitudinal strain (LVGLS) in patients undergoing transcatheter aortic valve implantation (TAVI). The aim of the present study was to evaluate the changes in cardiac damage stage and LVGLS after TAVI and to investigate their prognostic values when integrated into the follow-up assessment. Methods: Patients with severe aortic stenosis undergoing TAVI were hierarchi...
Abstract
Cited 3 times since 2024 (3.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 32, Issue 7-8, 2 1 2024, Pages 290-297
Impact of symptom duration and mechanical circulatory support on prognosis in cardiogenic shock complicating acute myocardial infarction.
Klein F, Crooijmans C, Peters EJ, van 't Veer M, Timmermans MJC, Henriques JPS, Verouden NJW, Kraaijeveld AO, Bunge JJH, Lipsic E, Sjauw KD, van Geuns RM, Dedic A, Dubois EA, Meuwissen M, Danse P, Bleeker G, Montero-Cabezas JM, Ferreira IA, Brouwer J, Teeuwen K, Otterspoor LC, PCI registration committee of the Netherlands Heart Registration
Background: Mortality rates in patients with cardiogenic shock complicating acute myocardial infarction (AMICS) remain high despite advancements in AMI care. Our study aimed to investigate the impact of prehospital symptom duration on the prognosis of AMICS patients and those receiving mechanical circulatory support (MCS). Methods and results: We conducted a retrospective cohort study with data registered in the Netherlands Heart Registration. A total of 1,363 patients with AMICS who underwent p...
Abstract
European journal of human genetics : EJHG,
Volume 32, Issue 11, 2 1 2024, Pages 1371-1377
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP2C19 and non-SSRI/non-TCA antidepressants.
Beunk L, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Guchelaar HJ, Houwink EJF, Risselada A, Rongen GAPJM, van Schaik RHN, Swen JJ, Touw D, Deneer VHM, van Westrhenen R
The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate pharmacogenetics implementation in clinical practice by developing evidence-based guidelines to optimize pharmacotherapy based on pharmacogenetic test results. The current guideline describes the gene-drug interaction between CYP2D6 and venlafaxine, mirtazapine and duloxetine. In addition, the interaction between CYP2C19 and mirtazapine and moclobemide is presented. The DPWG identified a gene-drug interaction that requires therap...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
Cancer immunology, immunotherapy : CII,
Volume 73, Issue 9, 2 1 2024, Pages 166
Monocyte infiltration is an independent positive prognostic biomarker in vulvar squamous cell carcinoma.
Abdulrahman Z, Kortekaas KE, Welters MJP, van Poelgeest MIE, van der Burg SH
Background: Vulvar squamous cell carcinoma (VSCC) arises after an HPV infection or the mutation of p53 or other driver genes and is treated by mutilating surgery and/or (chemo) radiation, with limited success and high morbidity. In-depth information on the immunological make up of VSCC is pivotal to assess whether immunotherapy may form an alternative treatment. Methods: A total of 104 patient samples, comprising healthy vulva (n = 27) and VSCC (n = 77), were analyzed. Multispectral immunofluore...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society,
2 1 2024, Pages ijgc-2024-005523
APOLLO: neo-adjuvant pembrolizumab for primary vulvar squamous cell carcinoma-a multicenter, single-arm, phase II, clinical proof-of-concept study.
van Poelgeest MIE, Kortekaas KE, van Doorn HC, Oonk M, Nijman HW, Boere I, Eerkens AL, Reyners AKL, Ewing-Graham PC, Bart J, Bosse T, Welters MJP, Kroep JR, van der Burg SH
Background: Vulvar squamous cell carcinoma (VSCC) is a rare cancer for which the cornerstone of treatment is surgery with high complication rates. The unmet need is a less radical and more effective treatment for VSCC. Primary objectives: To investigate the impact of mono-immunotherapy pembrolizumab as neoadjuvant treatment for primary resectable VSCC patients. Study hypothesis: Some primary VSCC patients display a specific immune profile which is associated with better survival. In other tumors...
Abstract
Cited 12 times since 2024 (13.2 per year)
source: EuropePMC
Age and ageing,
Volume 53, Issue 7, 1 1 2024, Pages afae129
A world-wide study on delirium assessments and presence of protocols.
Nydahl P, Liu K, Bellelli G, Benbenishty J, van den Boogaard M, Caplan G, Chung CR, Elhadi M, Gurjar M, Heras-La Calle G, Hoffmann M, Jeitziner MM, Krewulak K, Mailhot T, Morandi A, Nawa RK, Oh ES, Collet MO, Paulino MC, Lindroth H, von Haken R, WDAD Study Group
Background: Delirium is a common complication of older people in hospitals, rehabilitation and long-term facilities. Objective: To assess the worldwide use of validated delirium assessment tools and the presence of delirium management protocols. Design: Secondary analysis of a worldwide one-day point prevalence study on World Delirium Awareness Day, 15 March 2023. Setting: Cross-sectional online survey including hospitals, rehabilitation and long-term facilities. Methods: Participating clinician...
Abstract
Cited 3 times since 2024 (3.3 per year)
source: EuropePMC
Minerva cardiology and angiology,
Volume 73, Issue 2, 1 1 2024, Pages 219-237
Echocardiographic assessment of patient hemodynamics in heart failure.
Fortuni F, Morroni S, Biagioli P, Myagmardorj R, Viti C, Sforna S, Moscatelli S, Wu HW, Ambrosio G, Bax JJ, Ajmone Marsan N, Carluccio E
Heart failure (HF) is a clinical syndrome which is due to cardiac structural and/or functional abnormalities that result in elevated intra-cardiac pressures and/or inadequate cardiac output. Hemodynamic assessment in HF allows the identification and characterization of cardiac dysfunction, systemic and/or pulmonary congestion and the eventual impairment of systemic perfusion which are fundamental to phenotype HF, risk stratify HF patients and to guide their treatment. Patient hemodynamics can be...
Abstract
Cited 11 times since 2024 (12.1 per year)
source: EuropePMC
European heart journal,
Volume 45, Issue 25, 1 1 2024, Pages 2201-2213
Coexisting atrial fibrillation and cancer: time trends and associations with mortality in a nationwide Dutch study.
Chen Q, van Rein N, van der Hulle T, Heemelaar JC, Trines SA, Versteeg HH, Klok FA, Cannegieter SC
Background and aims: Coexisting atrial fibrillation (AF) and cancer challenge the management of both. The aim of the study is to comprehensively provide the epidemiology of coexisting AF and cancer. Methods: Using Dutch nationwide statistics, individuals with incident AF (n = 320 139) or cancer (n = 472 745) were identified during the period 2015-19. Dutch inhabitants without a history of AF (n = 320 135) or cancer (n = 472 741) were matched as control cohorts by demographic characteristics. Pre...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 25, Issue 8, 1 1 2024, Pages 1089-1098
Plasma lipidomics and coronary plaque changes: a substudy of the SMARTool clinical trial.
Smit JM, Rocchiccioli S, Signore G, Michelucci E, Di Giorgi N, van Rosendael AR, El Mahdiui M, Neglia D, Knuuti J, Saraste A, Buechel RR, Teresinska A, Pizzi MN, Roque A, Poddighe R, Mertens BJ, Caselli C, Parodi O, Pelosi G, Scholte AJ
Aims: To date, no studies have investigated the association between lipid species and coronary plaque changes over time, quantitatively assessed by serial imaging. We aimed to prospectively determine the association between lipid species quantified by a plasma lipidomic analysis and coronary plaque changes according to composition assessed by a quantitative serial analysis of coronary computed tomography angiography (CTA). Methods and results: Patients with suspected coronary artery disease (CAD...
Abstract
Cited 15 times since 2024 (16.5 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 116, Issue 4, 1 1 2024, Pages 939-947
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2D6, ADRB1, ADRB2, ADRA2C, GRK4, and GRK5 Genotypes and Beta-Blocker Therapy.
Duarte JD, Thomas CD, Lee CR, Huddart R, Agundez JAG, Baye JF, Gaedigk A, Klein TE, Lanfear DE, Monte AA, Nagy M, Schwab M, Stein CM, Uppugunduri CRS, van Schaik RHN, Donnelly RS, Caudle KE, Luzum JA
Beta-blockers are widely used medications for a variety of indications, including heart failure, myocardial infarction, cardiac arrhythmias, and hypertension. Genetic variability in pharmacokinetic (e.g., CYP2D6) and pharmacodynamic (e.g., ADRB1, ADRB2, ADRA2C, GRK4, GRK5) genes have been studied in relation to beta-blocker exposure and response. We searched and summarized the strength of the evidence linking beta-blocker exposure and response with the six genes listed above. The level of eviden...
Abstract
Cited 6 times since 2024 (6.6 per year)
source: EuropePMC
European heart journal,
Volume 45, Issue 25, 1 1 2024, Pages 2254-2258
Cardiac biomarkers for diagnosing Takotsubo syndrome.
Schweiger V, Di Vece D, Cammann VL, Koleva I, Würdinger M, Gilhofer T, Rajman K, Szawan KA, Niederseer D, Citro R, Vecchione C, Bossone E, Gili S, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Jansen T, D'Ascenzo F, Bruno F, De Filippo O, Stefanini G, Campo G, Wanha W, Raposeiras Roubin S, Dichtl W, von Lewinski D, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Massoomi M, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Kato K, Ishibashi I, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pesta
Abstract
The British journal of surgery,
Volume 111, Issue 7, 1 1 2024, Pages znae160
Minimally Invasive transCervical oEsophagectomy (MICE) for oesophageal cancer: prospective cohort study (IDEAL stage 2A).
Vercoulen RJMT, van Veenendaal L, Kramer IF, Hutteman M, Shiozaki A, Fujiwara H, Rosman C, Klarenbeek BR
Background: Minimally invasive transcervical oesophagectomy is a surgical technique that offers radical oesophagectomy without the need for transthoracic access. The aim of this study was to evaluate the safety and feasibility of the minimally invasive transcervical oesophagectomy procedure and to report the refinement of this technique in a Western cohort. Methods: A single-centre prospective cohort study was designed as an IDEAL stage 2A study. Patients with oesophageal cancer (cT1b-4a N0-3 M0...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 66, Issue 1, 1 1 2024, Pages ezae275
Hybrid palliation to promote growth of left ventricle and left ventricular outflow tract.
Eising JB, Bökenkamp R, Schneider AW, Kuipers IM, Hazekamp MG
Objectives: In patients with borderline left hearts or a severe left ventricular outflow tract obstruction, hybrid palliation can be used to stabilize the patient and postpone biventricular repair (BVR). In this study, we analysed growth of left-sided structures and outcomes of these patients. Methods: We conducted a retrospective cohort study including patients who received hybrid palliation between January 2010 and September 2023. Echo measurements were collected at hybrid palliation, BVR and...
Abstract
Cited 2 times since 2024 (2.2 per year)
source: EuropePMC
Thoracic research and practice,
Volume 25, Issue 4, 1 1 2024, Pages 162-167
Evaluation of Long-Coronavirus Disease 2019 Cases Readmitted to Intensive Care Units Due to Acute Respiratory Failure: Point Prevalence Study.
Tunçay E, Moçin Ö, Ediboğdu Ö, Adıgüzel N, Güngör S, İşcanlı İ, Er B, Mendil NA, Usalan A, Yılmaz D, Keskin H, Dönmez GE, Yılmaz B, Kargın F, Saraçoğlu KT, Temel Ş, Dal HC, Turan S, Talan L, Hoşgün D, Aydemir S, Sungurtekin H
Objective: Coronavirus disease 2019 (COVID-19) caused morbidity and mortality worldwide. Besides the acute effects, subacute and long-term effects are defined as long-COVID causing morbidity. The intensive care unit (ICU) data of long-COVID-19 cases were evaluated with the participation of 11 centers. Material and methods: Study was designed by Turkish Thoracic Society Respiratory Failure and Intensive Care Working Group to evaluate long COVID-19 patients. All patients followed up in the ICU w...
Abstract
Cited 3 times since 2024 (3.3 per year)
source: EuropePMC
Clinical and translational allergy,
Volume 14, Issue 7, 1 1 2024, Pages e12381
Dupilumab induces a significant decrease of food specific immunoglobulin E levels in pediatric atopic dermatitis patients.
van der Rijst LP, Hilbrands MS, Zuithoff NPA, de Bruin-Weller MS, Knulst AC, Le TM, de Graaf M
Abstract
Cited 7 times since 2024 (7.7 per year)
source: EuropePMC
European heart journal. Cardiovascular pharmacotherapy,
Volume 10, Issue 4, 1 1 2024, Pages 342-352
Safety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation.
Goodman SG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Harrington RA, Jukema JW, White HD, Zeiher AM, Manvelian G, Pordy R, Poulouin Y, Stipek W, Garon G, Schwartz GG, ODYSSEY OUTCOMES Investigators
The ODYSSEY OUTCOMES trial, comprising over 47 000 patient-years of placebo-controlled observation, demonstrated important reductions in the risk of recurrent ischaemic cardiovascular events with the monoclonal antibody to proprotein convertase subtilisin/kexin type 9 alirocumab, as well as lower all-cause death. These benefits were observed in the context of substantial and persistent lowering of low-density lipoprotein cholesterol with alirocumab compared with that achieved with placebo. The s...
Abstract
Interdisciplinary cardiovascular and thoracic surgery,
Volume 39, Issue 1, 1 1 2024, Pages ivae132
Quality of life improvement from thoracoscopic atrial fibrillation ablation in women versus men: a prospective cohort study.
Vos LM, Vos R, Nieuwkerk PT, Vos PWK, Hofman FN, Klautz RJM, Van Putte BP
Objectives: Thoracoscopic ablation has proven to be an effective and safe rhythm control strategy, especially for persistent atrial fibrillation. However, its impact on quality of life (QoL) and potential gender differences remains unclear. Methods: This prospective, single-centre observational study included consecutive patients with symptomatic atrial fibrillation undergoing thoracoscopic ablation. QoL was measured using the Short Form 36 (SF-36) and Atrial Fibrillation Effect on Quality-of-Li...
Abstract
