8684 results
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology,
Volume 35, Issue 6, 1 1 2024, Pages e14178
Effect of dupilumab on asthma and aeroallergen sensitization in pediatric atopic dermatitis patients: Results of the BioDay registry.
van der Rijst LP, de Winter-de Groot KM, Zuithoff NPA, de Bruin-Weller MS, de Graaf M
Background: Atopic dermatitis (AD) is frequently associated with asthma and allergic rhinitis (AR). Dupilumab is an effective treatment for pediatric AD, although the effect on atopic comorbidities in pediatric AD patients is limited. Objective: To investigate the prevalence of asthma and AR in pediatric AD patients starting dupilumab treatment and to evaluate the effect of dupilumab on these comorbidities. Methods: This study included pediatric AD patients (aged 3-17 years) treated with dupilum...
Abstract
Cited 3 times since 2024 (3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 26, Issue 6, 1 1 2024, Pages euae157
Body mass index and pulmonary vein isolation: real-world data on outcomes and quality of life.
Vermeer J, Houterman S, Medendorp N, van der Voort P, Dekker L, Ablation Registration Committee of the Netherlands Heart Registration
Aims: Increasing numbers of overweight and obese patients undergo pulmonary vein isolation (PVI), despite the association between higher body mass index (BMI) and adverse PVI outcomes. Evidence on complications and quality of life in different bodyweight groups is limited. This study aims to clarify the impact of BMI on repeat ablations, periprocedural complications, and changes in quality of life. Methods and results: This multi-centre study analysed prospectively collected data from 15 ablatio...
Abstract
JVS-vascular science,
Volume 5, 1 1 2024, Pages 100210
Basic Vascular Science 2024 Meeting.
Sluiter TJ, Cruddas L, Ninno F, Schmitz-Rixen T, Tsui J, de Vries MR
The Basic Vascular Science (BVS) meeting was set up to provide a forum for researchers and clinicians in the field to exchange knowledge and ideas and to foster cross-disciplinary collaborations. The BVS 2024 meeting was held in Berlin. Attended by vascular surgeons and physicians, interventional radiologists, basic science researchers, and engineers, the meeting continues to successfully attract both early career researchers and established clinician-scientists. Here, we report on the scientifi...
Abstract
Cited 2 times since 2024 (2 per year)
source: EuropePMC
Diabetes care,
Volume 47, Issue 6, 1 1 2024, Pages 1042-1047
Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.
Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). Research design and methods: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. Results: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18.2%). We identified three novel genetic loc...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
JMIR human factors,
Volume 11, 31 5 2024, Pages e45055
Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study.
de Frel DL, Schroijen MA, Aardoom JJ, van Gils W, Huisman SD, Janssen VR, Versluis A, Kleinsmann MS, Atsma DE, Pijl H
Background: Type 2 diabetes (T2D) tremendously affects patient health and health care globally. Changing lifestyle behaviors can help curb the burden of T2D. However, health behavior change is a complex interplay of medical, behavioral, and psychological factors. Personalized lifestyle advice and promotion of self-management can help patients change their health behavior and improve glucose regulation. Digital tools are effective in areas of self-management and have great potential to support pa...
Abstract
Cited 2 times since 2024 (2 per year)
source: EuropePMC
JMIR mental health,
Volume 11, 31 5 2024, Pages e46895
Characterizing Longitudinal Patterns in Cognition, Mood, And Activity in Depression With 6-Week High-Frequency Wearable Assessment: Observational Study.
Cormack F, McCue M, Skirrow C, Cashdollar N, Taptiklis N, van Schaik T, Fehnert B, King J, Chrones L, Sarkey S, Kroll J, Barnett JH
Background: Cognitive symptoms are an underrecognized aspect of depression that are often untreated. High-frequency cognitive assessment holds promise for improving disease and treatment monitoring. Although we have previously found it feasible to remotely assess cognition and mood in this capacity, further work is needed to ascertain the optimal methodology to implement and synthesize these techniques. Objective: The objective of this study was to examine (1) longitudinal changes in mood, cogni...
Abstract
Cited 8 times since 2024 (7.9 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 26, 31 5 2024, Pages e47515
Comparison of the Working Alliance in Blended Cognitive Behavioral Therapy and Treatment as Usual for Depression in Europe: Secondary Data Analysis of the E-COMPARED Randomized Controlled Trial.
Doukani A, Quartagno M, Sera F, Free C, Kakuma R, Riper H, Kleiboer A, Cerga-Pashoja A, van Schaik A, Botella C, Berger T, Chevreul K, Matynia M, Krieger T, Hazo JB, Draisma S, Titzler I, Topooco N, Mathiasen K, Vernmark K, Urech A, Maj A, Andersson G, Berking M, Baños RM, Araya R
Background: Increasing interest has centered on the psychotherapeutic working alliance as a means of understanding clinical change in digital mental health interventions in recent years. However, little is understood about how and to what extent a digital mental health program can have an impact on the working alliance and clinical outcomes in a blended (therapist plus digital program) cognitive behavioral therapy (bCBT) intervention for depression. Objective: This study aimed to test the differ...
Abstract
Ground water,
Volume 62, Issue 5, 30 5 2024, Pages 804-816
A Case Study for Determination of the Best Underground Dam Sites, Bursa Province, Turkey.
Aras E, Boz B, Vaheddoost B, Yılmaz D
Water constitutes an indispensable resource vital for sustaining life. In this context, groundwater stands out as a paramount global water source. Throughout history, underground dams (UGDs) have been employed to augment the storage capacity of local aquifers. This study employs a multistep elimination approach to identify optimal locations for constructing UGDs in the Bursa district, Turkey. Initially, the Digital Elevation Model (DEM) is utilized to pinpoint the potential construction sites at...
Abstract
JTCVS open,
Volume 20, 29 5 2024, Pages 210
Involving the next generation of cardiovascular surgeons.
Sier VQ, Blok JJ, Akca F, Hjortnaes J, van der Vorst JR
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Small methods,
Volume 8, Issue 12, 28 4 2024, Pages e2400203
Direct Fabrication of Atomically Defined Pores in MXenes Using Feedback-Driven STEM.
Boebinger MG, Yilmaz DE, Ghosh A, Misra S, Mathis TS, Kalinin SV, Jesse S, Gogotsi Y, van Duin ACT, Unocic RR
Controlled fabrication of nanopores in 2D materials offer the means to create robust membranes needed for ion transport and nanofiltration. Techniques for creating nanopores have relied upon either plasma etching or direct irradiation; however, aberration-corrected scanning transmission electron microscopy (STEM) offers the advantage of combining a sub-Å sized electron beam for atomic manipulation along with atomic resolution imaging. Here, a method for automated nanopore fabrication is utilized...
Abstract
REC, interventional cardiology,
Volume 6, Issue 3, 27 4 2024, Pages 213-223
[Use of cardiovascular registries in regulatory pathways: perspectives from the EU-MDR Cardiovascular Collaboratory].
Spitzer E, de la Torre Hernández JM, Guðmundsdóttir IJ, McFadden E, Held C, Hanet C, Boersma E, Ren CB, Delgado V, Erlinge D, Pérez de Prado A, Bax JJ, Tijssen JGP
On May 26, 2021, the European Medical Device Regulation (EU-MDR) entered into effect resulting in a major shift in the requirements for assessment of medical devices in Europe. The EU-MDR Cardiovascular Collaboratory (EU-MCVC) was founded to contribute to the development of faster, more efficient, and more effective pathways for innovation of cardiac medical devices. A registry is an organized system that collects uniform data and evaluates specified outcomes in a population defined by a disease...
Abstract
JACC. Case reports,
Volume 29, Issue 13, 24 4 2024, Pages 102382
Myocardial Bridging as a Trigger in Angina With No Obstructive Coronary Artery Disease.
Beijk MAM, Woudstra J, Vink AS, Bijsterveld NR, de Lind van Wijngaarden RAF, Klautz RJM
We present 2 patients with angina with no obstructive coronary artery disease and concomitant myocardial bridging. Despite maximal tolerated pharmacotherapy, symptoms remained. Invasive anatomical and hemodynamic assessment identified myocardial bridging as a contributing cause of angina. Following heart team discussion, both patients underwent successful coronary artery unroofing of the left anterior descending artery.
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Brain sciences,
Volume 14, Issue 6, 24 4 2024, Pages 533
Sensational Dreams: The Prevalence of Sensory Experiences in Dreaming.
van der Heijden AC, Thevis J, Verhaegen J, Talamini LM
Dreaming, a widely researched aspect of sleep, often mirrors waking-life experiences. Despite the prevalence of sensory perception during wakefulness, sensory experiences in dreams remain relatively unexplored. Free recall dream reports, where individuals describe their dreams freely, may not fully capture sensory dream experiences. In this study, we developed a dream diary with direct questions about sensory dream experiences. Participants reported sensory experiences in their dreams upon awake...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Chemistry (Weinheim an der Bergstrasse, Germany),
Volume 30, Issue 34, 24 4 2024, Pages e202400283
Understanding the Remarkable Stability of Well-Defined Dinuclear Copper(I) Carbene Complexes.
Bienenmann RLM, de Vries MR, Lutz M, Broere DLJ
The synthesis of a well-defined dicopper carbene complex supported by the PNNP (2,7-bis(di-tert-butylphosphaneyl)methyl-1,8-naphthyridine) expanded pincer ligand is reported. This carbene complex is remarkably stable, even in the presence of air and water. The reactivity of this complex was explored towards typical carbene transfer substrates and its electronic structure was investigated. Using a combination of experiments and DFT calculations, the principles that underly the stability of dinucl...
Abstract
Cited 8 times since 2024 (7.7 per year)
source: EuropePMC
JACC. Advances,
Volume 3, Issue 5, 22 4 2024, Pages 100959
Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement: Meta-Analysis.
Abdelfattah OM, Jacquemyn X, Sá MP, Jneid H, Sultan I, Cohen DJ, Gillam LD, Aron L, Clavel MA, Pibarot P, Bax JJ, Kapadia SR, Leon M, Généreux P
Background: The prognostic value of cardiac damage staging classification based on the extent of extravalvular damage has been proposed in moderate/severe aortic stenosis (AS). Objectives: The purpose of this study was to assess the association of cardiac damage staging with mortality across the spectrum of patients with AS following aortic surgical or transcatheter aortic valve replacement (AVR). Methods: We conducted a pooled meta-analysis of Kaplan-Meier-derived reconstructed time-to-event da...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
ESC heart failure,
Volume 11, Issue 5, 22 4 2024, Pages 2499-2509
In vivo fluid dynamics of the Ventura interatrial shunt device in patients with heart failure.
Pfeiffer M, Boehmer J, Gorcsan J, Eguchi S, Orihara Y, Perl ML, Eigler N, Abraham WT, Villota JN, Lee E, Bayés-Genís A, Moravsky G, Kar S, Zile MR, Holcomb R, Anker SD, Stone GW, Rodés-Cabau J, Lindenfeld J, Bax JJ
Aims: Interatrial shunts are under evaluation as a treatment for heart failure (HF); however, their in vivo flow performance has not been quantitatively studied. We aimed to investigate the fluid dynamics properties of the 0.51 cm orifice diameter Ventura shunt and assess its lumen integrity with serial transesophageal echocardiography (TEE). Methods and results: Computational fluid dynamics (CFD) and bench flow tests were used to establish the flow-pressure relationship of the shunt. Open-label...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 17, Issue 9, 22 4 2024, Pages 1015-1027
Left Atrial Improvement in Patients With Secondary Mitral Regurgitation and Heart Failure: The COAPT Trial.
Pio SM, Medvedofsky D, Delgado V, Stassen J, Weissman NJ, Grayburn PA, Kar S, Lim DS, Redfors B, Snyder C, Zhou Z, Alu MC, Kapadia SR, Lindenfeld J, Abraham WT, Mack MJ, Asch FM, Stone GW, Bax JJ, COAPT Trial Investigators
Background: Functional mitral regurgitation induces adverse effects on the left ventricle and the left atrium. Left atrial (LA) dilatation and reduced LA strain are associated with poor outcomes in heart failure (HF). Transcatheter edge-to-edge repair (TEER) of the mitral valve reduces heart failure hospitalization (HFH) and all-cause death in selected HF patients. Objectives: The aim of this study was to evaluate the impact of LA strain improvement 6 months after TEER on the outcomes of patient...
Abstract
Cited 14 times since 2024 (13.4 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 17, Issue 8, 22 4 2024, Pages 847-860
Diagnostic Value of Aortic Valve Calcification Levels in the Assessment of Low-Gradient Aortic Stenosis.
Adrichem R, Hokken TW, Bouwmeester S, Abdelkarim O, Vogel B, Blusztein DI, Veulemans V, Kuneman JH, Geleijnse ML, Verhemel S, Van den Dorpel MMP, Kardys I, Tonino PAL, Chang SM, Faza NN, Jou S, Ueyama HA, Bartkowiak J, Zeus T, Bax JJ, Bertrand PB, Hahn RT, Kodali SK, Lerakis S, Mehran R, Little SH, Houthuizen P, Van Mieghem NM
Background: In patients with low-gradient aortic stenosis (AS) and low transvalvular flow, dobutamine stress echocardiography (DSE) is recommended to determine AS severity, whereas the degree of aortic valve calcification (AVC) supposedly correlates with AS severity according to current European and American guidelines. Objectives: The purpose of this study was to assess the relationship between AVC and AS severity as determined using echocardiography and DSE in patients with aortic valve area
Abstract
Cited 3 times since 2024 (2.9 per year)
source: EuropePMC
Behavior research methods,
Volume 56, Issue 7, 21 3 2024, Pages 7331-7344
Optimal processing of surface facial EMG to identify emotional expressions: A data-driven approach.
Rutkowska JM, Ghilardi T, Vacaru SV, van Schaik JE, Meyer M, Hunnius S, Oostenveld R
Surface facial electromyography (EMG) is commonly used to detect emotions from subtle facial expressions. Although there are established procedures for collecting EMG data and some aspects of their processing, there is little agreement among researchers about the optimal way to process the EMG signal, so that the study-unrelated variability (noise) is removed, and the emotion-related variability is best detected. The aim of the current paper was to establish an optimal processing pipeline for EM...
Abstract
Autism research : official journal of the International Society for Autism Research,
Volume 17, Issue 6, 21 3 2024, Pages 1126-1139
Specialization of anterior and posterior hippocampal functional connectivity differs in autism.
Kember J, Patenaude P, Sweatman H, Van Schaik L, Tabuenca Z, Chai XJ
Structural and functional differences in the hippocampus have been related to the episodic memory and social impairments observed in autism spectrum disorder (ASD). In neurotypical individuals, hippocampal-cortical functional connectivity systematically varies between anterior and posterior hippocampus, with changes observed during typical development. It remains unknown whether this specialization of anterior-posterior hippocampal connectivity is disrupted in ASD, and whether age-related differ...
Abstract
