Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9543 results
Cited 19 times since 2016 (2 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 67, Issue 9, 1 1 2016, Pages 1123-1124 Pulmonary Valve Replacement After Repair of Pulmonary Stenosis Compared With Tetralogy of Fallot. Bokma JP, Winter MM, Oosterhof T, Vliegen HW, van Dijk AP, Pieper PG, Meijboom FJ, Groenink M, Mulder BJM, Bouma BJ
Cited 412 times since 2016 (42.3 per year) source: EuropePMC
Science (New York, N.Y.), Volume 351, Issue 6278, 1 1 2016, Pages 1166-1171 Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdmann J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ, CHD Exome+ Consortium, CARDIoGRAM Exome Consortium, Global Lipids Genetics Consortium
Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL) cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a lower risk of coronary heart disease (CHD). Mice that have depleted Scarb1 (SR-BI knockout mice) have markedly elevated HDL-C levels but, paradoxically, increased atherosclerosis. The impact of SR-BI on HDL metabolism and CHD risk in humans remains unclear. Through targeted sequencing of coding regions of lipid-modifying gene... Abstract
Cited 4 times since 2016 (0.4 per year) source: EuropePMC
Journal of atrial fibrillation, Volume 8, Issue 5, 29 5 2016, Pages 1362 Cardiac Resynchronization Therapy in Non-Ischemic Cardiomyopathy. Shanks M, Delgado V, Bax JJ
Cardiac resynchronization therapy (CRT) is an established therapy for heart failure patients who remain symptomatic despite optimal medical therapy, have reduced left ventricular ejection fraction (120 ms), preferably with left bundle branch block morphology. The response to CRT depends on the cardiac substrate: presence of correctable left ventricular mechanical dyssynchrony, presence of myocardial fibrosis (scar) and position of the left ventricular pacing lead. Patients with non-ischemic card... Abstract
Cited 121 times since 2016 (12.4 per year) source: EuropePMC
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Volume 16, Issue 7, 26 4 2016, Pages 2085-2096 A Randomized Controlled Trial Comparing the Efficacy of Cyp3a5 Genotype-Based With Body-Weight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation. Shuker N, Bouamar R, van Schaik RH, Clahsen-van Groningen MC, Damman J, Baan CC, van de Wetering J, Rowshani AT, Weimar W, van Gelder T, Hesselink DA
Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with nonexpressers. This randomized-controlled study investigated whether adaptation of the tacrolimus starting dose according to CYP3A5 genotype increases the proportion of kidney transplant recipients being within the target tacrolimus predose concentration range (10-15 ng/mL) at first steady-state. Two hundred forty living-donor, renal transplant recipients were ass... Abstract
Cited 19 times since 2016 (2 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 22, Issue 6, 25 4 2016, Pages 817-825 Is the Lecompte technique the last word on transposition of the great arteries repair for all patients? A magnetic resonance imaging study including a spiral technique two decades postoperatively. Rickers C, Kheradvar A, Sievers HH, Falahatpisheh A, Wegner P, Gabbert D, Jerosch-Herold M, Hart C, Voges I, Putman LM, Kristo I, Fischer G, Scheewe J, Kramer HH
Objectives: To compare the Lecompte technique and the spiral anastomosis (complete anatomic correction) two decades after arterial switch operation (ASO). Methods: Nine patients after primary ASO with Lecompte and 6 selected patients after spiral anastomosis were evaluated 20.8 ± 2.1 years after ASO versus matched controls. Blood flow dynamics and flow profiles (e.g. vorticity, helicity) in the great arteries were quantified from time-resolved 3D magnetic resonance imaging (MRI) phase contrast f... Abstract
Cited 63 times since 2016 (6.5 per year) source: EuropePMC
Genome research, Volume 26, Issue 4, 25 4 2016, Pages 417-426 Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck. Li M, Rothwell R, Vermaat M, Wachsmuth M, Schröder R, Laros JF, van Oven M, de Bakker PI, Bovenberg JA, van Duijn CM, van Ommen GJ, Slagboom PE, Swertz MA, Wijmenga C, Genome of Netherlands Consortium, Kayser M, Boomsma DI, Zöllner S, de Knijff P, Stoneking M
Although previous studies have documented a bottleneck in the transmission of mtDNA genomes from mothers to offspring, several aspects remain unclear, including the size and nature of the bottleneck. Here, we analyze the dynamics of mtDNA heteroplasmy transmission in the Genomes of the Netherlands (GoNL) data, which consists of complete mtDNA genome sequences from 228 trios, eight dizygotic (DZ) twin quartets, and 10 monozygotic (MZ) twin quartets. Using a minor allele frequency (MAF) threshold... Abstract
Cited 29 times since 2016 (3 per year) source: EuropePMC
BMC neurology, Volume 16, 24 4 2016, Pages 25 Pain management strategies for neuropathic pain in Fabry disease--a systematic review. Schuller Y, Linthorst GE, Hollak CE, Van Schaik IN, Biegstraaten M
Background: Neuropathic pain is one of the key features of (classical) Fabry disease (FD). No randomized clinical trials comparing effectiveness of different pain management strategies have been performed. This review aims to give an overview of existing pain management strategies. Methods: PubMed and Embase were searched up to September 2014 for relevant articles on treatment of neuropathic pain in FD. Results: Seven-hundred-thirty-one articles were identified of which 26 were included in the a... Abstract
Cited 32 times since 2016 (3.3 per year) source: EuropePMC
Journal of human evolution, Volume 92, 24 4 2016, Pages 91-100 Life history, cognition and the evolution of complex foraging niches. Schuppli C, Graber SM, Isler K, van Schaik CP
Animal species that live in complex foraging niches have, in general, improved access to energy-rich and seasonally stable food sources. Because human food procurement is uniquely complex, we ask here which conditions may have allowed species to evolve into such complex foraging niches, and also how niche complexity is related to relative brain size. To do so, we divided niche complexity into a knowledge-learning and a motor-learning dimension. Using a sample of 78 primate and 65 carnivoran spec... Abstract
Cited 9 times since 2016 (0.9 per year) source: EuropePMC
Journal of theoretical biology, Volume 396, 23 4 2016, Pages 53-62 The impact of host metapopulation structure on the population genetics of colonizing bacteria. Numminen E, Gutmann M, Shubin M, Marttinen P, Méric G, van Schaik W, Coque TM, Baquero F, Willems RJ, Sheppard SK, Feil EJ, Hanage WP, Corander J
Many key bacterial pathogens are frequently carried asymptomatically, and the emergence and spread of these opportunistic pathogens can be driven, or mitigated, via demographic changes within the host population. These inter-host transmission dynamics combine with basic evolutionary parameters such as rates of mutation and recombination, population size and selection, to shape the genetic diversity within bacterial populations. Whilst many studies have focused on how molecular processes underpin... Abstract
Revista espanola de cardiologia (English ed.), Volume 69, Issue 4, 23 4 2016, Pages 460-461 Could Descending Septal Artery Be Another Variant of the Dual Left Anterior Descending Artery? Response. Montero-Cabezas JM, Delgado V, Karalis I, Schalij MJ
Cited 11 times since 2016 (1.1 per year) source: EuropePMC
Journal of internal medicine, Volume 279, Issue 6, 23 4 2016, Pages 592-605 Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. Frodermann V, van Duijn J, van Puijvelde GH, van Santbrink PJ, Lagraauw HM, de Vries MR, Quax PH, Bot I, Foks AC, de Jager SC, Kuiper J
Background: Staphylococcus aureus cell wall components can induce IL-10 responses by immune cells, which may be atheroprotective. Therefore, in this study, we investigated whether heat-killed S. aureus (HK-SA) could inhibit the development of atherosclerosis. Methods: Atherosclerosis-susceptible LDL receptor-deficient mice were administered intraperitoneal HK-SA twice weekly and fed a Western-type diet for 6 weeks. Results: HK-SA administration resulted in a 1.6-fold increase in IL-10 production... Abstract
Cited 109 times since 2016 (11.2 per year) source: EuropePMC
Cardiovascular research, Volume 110, Issue 1, 23 4 2016, Pages 6-22 The multifactorial nature of microRNAs in vascular remodelling. Welten SM, Goossens EA, Quax PH, Nossent AY
Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive changes of the vessel wall through, among others, cell proliferation and migration, but also apoptosis and necrosis of the various cell types in the vessel wall. Vascular remodelling can be beneficial, e.g. during neovascularization after ischaemia, as well as pathological, e.g. during atherosclerosis and aneurysm formation. In recent years, it has become clear that microRNAs are able to target many gene... Abstract
Cited 27 times since 2016 (2.8 per year) source: EuropePMC
European heart journal, Volume 37, Issue 47, 22 4 2016, Pages 3536-3543 The 200th anniversary of the stethoscope: Can this low-tech device survive in the high-tech 21st century? Bank I, Vliegen HW, Bruschke AV
In 1816, Laennec discovered that auscultation of the heart and lungs could effectively be performed by placing a hollow cylinder (initially made of a roll of paper) between the chest of the patient and the ear of the examiner. This was the first step in the development of the stethoscope, which was a breakthrough in the diagnosis and management of cardiac and pulmonary patients. Technical improvements of the stethoscope followed and in cardiac patients auscultation soon became a major diagnostic... Abstract
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Volume 62, Issue 9, 21 3 2016, Pages 1194-1195 Reply to Deeny et al. Hetem DJ, Bootsma MC, Bonten MJ
Cited 11 times since 2016 (1.1 per year) source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD, Volume 26, Issue 8, 19 3 2016, Pages 697-705 HDL functionality in South Asians as compared to white Caucasians. Bakker LE, Boon MR, Annema W, Dikkers A, van Eyk HJ, Verhoeven A, Mayboroda OA, Jukema JW, Havekes LM, Meinders AE, Willems van Dijk K, Jazet IM, Tietge UJ, Rensen PC
Background and aims: South Asians have an exceptionally high risk of developing cardiovascular disease compared to white Caucasians. A contributing factor might be dysfunction of high density lipoprotein (HDL). We aimed to compare HDL function in different age groups of both ethnicities. Methods and results: HDL functionality with respect to cholesterol efflux, anti-oxidation and anti-inflammation was determined using fasting, apoB-depleted, plasma samples from South Asian and white Caucasian ne... Abstract
Cited 37 times since 2016 (3.8 per year) source: EuropePMC
The British journal of psychiatry : the journal of mental science, Volume 208, Issue 4, 18 3 2016, Pages 366-373 Discontinuation of antidepressant medication after mindfulness-based cognitive therapy for recurrent depression: randomised controlled non-inferiority trial. Huijbers MJ, Spinhoven P, Spijker J, Ruhé HG, van Schaik DJ, van Oppen P, Nolen WA, Ormel J, Kuyken W, van der Wilt GJ, Blom MB, Schene AH, Rogier A, Donders T, Speckens AE
Background: Mindfulness-based cognitive therapy (MBCT) and maintenance antidepressant medication (mADM) both reduce the risk of relapse in recurrent depression, but their combination has not been studied. Aims: To investigate whether MBCT with discontinuation of mADM is non-inferior to MBCT+mADM. Method: A multicentre randomised controlled non-inferiority trial (ClinicalTrials.gov:NCT00928980). Adults with recurrent depression in remission, using mADM for 6 months or longer (n= 249), were random... Abstract
Cited 48 times since 2016 (4.9 per year) source: EuropePMC
Neurology, Volume 86, Issue 12, 17 3 2016, Pages 1120-1127 10-Second heart rate variability and cognitive function in old age. Mahinrad S, Jukema JW, van Heemst D, Macfarlane PW, Clark EN, de Craen AJ, Sabayan B
Objective: To investigate the cross-sectional and longitudinal associations of 10-second heart rate variability (HRV) with various domains of cognitive function in older participants at risk of cardiovascular disease. Methods: We studied 3,583 participants, mean age of 75.0 years, who were enrolled in the Prospective Study of Pravastatin in the Elderly at Risk. From baseline 10-second ECGs, standard deviation of normal-to-normal intervals was calculated as the index of HRV. Four cognitive domain... Abstract
Cited 5 times since 2016 (0.5 per year) source: EuropePMC
Journal of child neurology, Volume 31, Issue 7, 16 3 2016, Pages 929-931 Is Celiac Disease an Etiological Factor in Children With Migraine? Balcı O, Yılmaz D, Sezer T, Hızlı Ş
To determine the prevalence of celiac disease in children and adolescents with migraine, the authors investigated serum levels of tissue transglutaminase antibody immunoglobulin A and total immunoglobulin A from 81 children with migraine and in a healthy control group of 176 children. Study participants who were positive for tissue transglutaminase immunoglobulin A antibodies underwent a duodenal biopsy. Two patients in the migraine group (2.5%) and 1 in the control group (0.57%) tested positive... Abstract
Cited 23 times since 2016 (2.4 per year) source: EuropePMC
European journal of preventive cardiology, Volume 23, Issue 13, 16 3 2016, Pages 1383-1392 High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk. Wijsman LW, de Craen AJ, Trompet S, Sabayan B, Muller M, Stott DJ, Ford I, Welsh P, Westendorp RG, Jukema JW, Sattar N, Mooijaart SP
Aims: Cardiac troponin T (cTnT), measured with a high-sensitivity (hs) assay, is associated with cognitive decline, but the underlying mechanism is unknown. We investigated the association of hs-cTnT with cognitive function and decline, and studied whether this association was independent of cardiovascular diseases or risk factors, and N-terminal pro-brain natriuretic peptide (NT-proBNP). Methods and results: We studied 5407 participants (mean age 75.31 years) from the PROspective Study of Prava... Abstract
Cited 34 times since 2016 (3.5 per year) source: EuropePMC
Atherosclerosis, Volume 247, 15 3 2016, Pages 135-141 High-sensitivity Troponin T in relation to coronary plaque characteristics in patients with stable coronary artery disease; results of the ATHEROREMO-IVUS study. Oemrawsingh RM, Cheng JM, García-García HM, Kardys I, van Schaik RH, Regar E, van Geuns RJ, Serruys PW, Boersma E, Akkerhuis KM
Background and aims: To assess the relationship between the extent and phenotype of coronary atherosclerosis, as assessed by in-vivo grayscale and radiofrequency intravascular ultrasound (IVUS), and circulating Troponin levels in patients with established stable coronary artery disease (CAD). Methods: In this single-center, cross-sectional analysis, high-sensitivity Troponin T (hsTnT) was measured and IVUS was performed in a predefined non-stenotic segment of a non-culprit coronary artery in 231... Abstract