Research

Publications

Below you can find a list of our published research.

9543 results

Cited 7 times since 2016 (0.7 per year) source: EuropePMC

BMJ case reports, Volume 2016, 15 3 2016, Pages bcr2015213106 Multiple carpometacarpal dislocations and an associated fracture of the hamate: an uncommon injury. Brinkman JN, Hartholt KA, de Vries MR

Dislocation of the four ulnar carpometacarpal (CMC) joints with a concurrent fracture of the hamate is a rare injury, with a paucity of published cases. A great force is required to dislocate a CMC joint. Diagnosis can easily be missed, due to other serious associated injuries. Appropriate treatment of CMC joint dislocations usually leads to excellent outcomes. We present a case of dorsal dislocation of the four ulnar CMC joints after punching a wall. The injury was treated with a closed reducti... Abstract

Cited 41 times since 2016 (4.2 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 36, Issue 4, 11 2 2016, Pages 757-764 Effect of Coronary Atherosclerosis and Myocardial Ischemia on Plasma Levels of High-Sensitivity Troponin T and NT-proBNP in Patients With Stable Angina. Caselli C, Prontera C, Liga R, De Graaf MA, Gaemperli O, Lorenzoni V, Ragusa R, Marinelli M, Del Ry S, Rovai D, Giannessi D, Aguade-Bruix S, Clemente A, Bax JJ, Lombardi M, Sicari R, Zamorano J, Scholte AJ, Kaufmann PA, Knuuti J, Underwood SR, Clerico A, Neglia D

Objective: Circulating levels of high-sensitivity cardiac troponin T (hs-cTnT) and N terminal pro brain natriuretic peptide (NT-proBNP) are predictors of prognosis in patients with coronary artery disease (CAD). We aimed at evaluating the effect of coronary atherosclerosis and myocardial ischemia on cardiac release of hs-cTnT and NT-proBNP in patients with suspected CAD. Approach and results: Hs-cTnT and NT-proBNP were measured in 378 patients (60.1±0.5 years, 229 males) with stable angina and u... Abstract

Cited 49 times since 2016 (5 per year) source: EuropePMC

Journal of dairy science, Volume 99, Issue 4, 10 2 2016, Pages 2930-2939 Evaluation of udder health parameters and risk factors for clinical mastitis in Dutch dairy herds in the context of a restricted antimicrobial usage policy. Santman-Berends IMGA, Swinkels JM, Lam TJGM, Keurentjes J, van Schaik G

Recently, many changes have been implemented in Dutch dairy herds. Herd sizes have increased and antimicrobial use has been reduced. Certain types of antimicrobials can only be used in specific circumstances, and the preventive use of antimicrobials in dry cows is prohibited. The aim of this study was to quantify clinical mastitis (CM), subclinical mastitis (SCM), and risk factors associated with CM in Dutch dairy herds in 2013, in the context of these changes. For this study, 240 dairy herds we... Abstract

Cited 17 times since 2016 (1.7 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 102, Issue 12, 10 2 2016, Pages 943-949 Coronary anatomy as related to bicuspid aortic valve morphology. Koenraadt WM, Tokmaji G, DeRuiter MC, Vliegen HW, Scholte AJ, Siebelink HM, Gittenberger-de Groot AC, de Graaf MA, Wolterbeek R, Mulder BJ, Bouma BJ, Schalij MJ, Jongbloed MR

Objective: Variable coronary anatomy has been described in patients with bicuspid aortic valves (BAVs). This was never specified to BAV morphology, and prognostic relevance of coronary vessel dominance in this patient group is unclear. The purpose of this study was to evaluate valve morphology in relation to coronary artery anatomy and outcome in patients with isolated BAV and with associated aortic coarctation (CoA). Methods: Coronary anatomy was evaluated in 186 patients with BAV (141 men (79%... Abstract

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 50, Issue 1, 9 2 2016, Pages 190 Reply to Mannacio et al. Gielen CL, Bruggemans EF, Brand A, Klautz RJ

Abstract

Cited 12 times since 2016 (1.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 24, Issue 4, 9 2 2016, Pages 1253-1262 Relation between quantitative coronary CTA and myocardial ischemia by adenosine stress myocardial CT perfusion. van Rosendael AR, Kroft LJ, Broersen A, Dijkstra J, van den Hoogen IJ, van Zwet EW, Bax JJ, de Graaf MA, Scholte AJ

Background: Coronary-computed tomography angiography (CTA) has limited accuracy to predict myocardial ischemia. Besides luminal area stenosis, other coronary plaque morphology and composition parameters may help to assess ischemia. With the integration of coronary CTA and adenosine stress CT myocardial perfusion (CTP), reliable information regarding coronary anatomy and function can be derived in one procedure. This analysis aimed to investigate the association between coronary stenosis severity... Abstract

Cited 91 times since 2016 (9.3 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 101, Issue 5, 6 1 2016, Pages 1684-1689 Bentall Procedure: A Systematic Review and Meta-Analysis. Mookhoek A, Korteland NM, Arabkhani B, Di Centa I, Lansac E, Bekkers JA, Bogers AJ, Takkenberg JJ

Background: The Bentall procedure is considered the gold standard in the treatment of patients requiring aortic root replacement. An up-to-date overview of outcomes after the Bentall procedure is lacking. Methods: We conducted a systematic review and meta-analysis of characteristics of and long-term outcome after the Bentall procedure with a mechanical valve prosthesis. Pooling was performed using the inverse variance method within a random-effects model. Outcome events are reported as linearize... Abstract

Cited 9 times since 2016 (0.9 per year) source: EuropePMC

Differentiation; research in biological diversity, Volume 91, Issue 4-5, 5 1 2016, Pages 90-103 The avian embryo to study development of the cardiac conduction system. Kelder TP, Vicente-Steijn R, Poelmann RE, Mummery CL, DeRuiter MC, Jongbloed MR

The avian embryo has long been a popular model system in developmental biology. The easy accessibility of the embryo makes it particularly suitable for in ovo microsurgery and manipulation. Re-incubation of the embryo allows long-term follow-up of these procedures. The current review focuses on the variety of techniques available to study development of the cardiac conduction system in avian embryos. Based on the large amount of relevant data arising from experiments in avian embryos, we conclud... Abstract

Cited 15 times since 2016 (1.5 per year) source: EuropePMC

Journal of visualized experiments : JoVE, Issue 108, 3 1 2016, Pages e53294 A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail. Wong CY, de Vries MR, Wang Y, van der Vorst JR, Vahrmeijer AL, van Zonneveld AJ, Hamming JF, Roy-Chaudhury P, Rabelink TJ, Quax PH, Rotmans JI

The arteriovenous fistula (AVF) still suffers from a high number of failures caused by insufficient remodeling and intimal hyperplasia from which the exact pathophysiology remains unknown. In order to unravel the pathophysiology a murine model of AVF-failure was developed in which the configuration of the anastomosis resembles the preferred situation in the clinical setting. A model was described in which an AVF is created by connecting the venous end of the branch of the external jugular vein t... Abstract

The American journal of cardiology, Volume 117, Issue 7, 2 1 2016, Pages 1167-1172 Comparison of Left Ventricular Volume and Ejection Fraction and Frequency and Extent of Aortic Regurgitation After Operative Repair of Type A Aortic Dissection Among Three Different Surgical Techniques. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V

Differences in recurrence rate of aortic regurgitation (AR) and extent of left ventricular (LV) remodeling across the different surgical options in patients operated for type A aortic dissection remain unknown. The present evaluation compared the AR recurrence rate and changes in LV volumes and systolic function in valve-sparing aorta replacement (VSAR), supracoronary ascending aorta replacement (SCAR), and aortic valve and aorta replacement (AVAR). A total of 97 patients (58 ± 12 years, 62% men... Abstract

Cited 18 times since 2016 (1.8 per year) source: EuropePMC

European journal of endocrinology, Volume 174, Issue 5, 2 1 2016, Pages 563-571 Time to insulin initiation and long-term effects of initiating insulin in people with type 2 diabetes mellitus: the Hoorn Diabetes Care System Cohort Study. Mast R, Danielle Jansen AP, Walraven I, Rauh SP, van der Heijden AA, Heine RJ, Elders PJ, Dekker JM, Nijpels G, Hugtenburg JG

Objective: The aim of this study was to assess the time to insulin initiation in type 2 diabetes mellitus (T2DM) patients treated with oral glucose-lowering agents and to determine the baseline characteristics associated with time to insulin initiation. This was evaluated in T2DM patients with HbA1c levels consistently ≥7.0% during total follow up and in those with fluctuating HbA1c levels around 7.0%. Design and methods: Prospective, observational study was performed, comprising 2418 persons wi... Abstract

Cited 40 times since 2016 (4.1 per year) source: EuropePMC

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Volume 371, Issue 1687, 1 1 2016, Pages 20150098 How institutions shaped the last major evolutionary transition to large-scale human societies. Powers ST, van Schaik CP, Lehmann L

What drove the transition from small-scale human societies centred on kinship and personal exchange, to large-scale societies comprising cooperation and division of labour among untold numbers of unrelated individuals? We propose that the unique human capacity to negotiate institutional rules that coordinate social actions was a key driver of this transition. By creating institutions, humans have been able to move from the default 'Hobbesian' rules of the 'game of life', dete... Abstract

Cited 22 times since 2016 (2.2 per year) source: EuropePMC

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Volume 371, Issue 1687, 1 1 2016, Pages 20150091 Why mutual helping in most natural systems is neither conflict-free nor based on maximal conflict. Bshary R, Zuberbühler K, van Schaik CP

Mutual helping for direct benefits can be explained by various game theoretical models, which differ mainly in terms of the underlying conflict of interest between two partners. Conflict is minimal if helping is self-serving and the partner benefits as a by-product. In contrast, conflict is maximal if partners are in a prisoner's dilemma with both having the pay-off-dominant option of not returning the other's investment. Here, we provide evolutionary and ecological arguments for why t... Abstract

Cited 187 times since 2016 (19.1 per year) source: EuropePMC

Inflammatory bowel diseases, Volume 22, Issue 2, 1 1 2016, Pages 345-354 Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe: Results from the EPIC Study. Racine A, Carbonnel F, Chan SS, Chan SS, Hart AR, Bueno-de-Mesquita HB, Oldenburg B, van Schaik FD, Tjønneland A, Olsen A, Dahm CC, Key T, Luben R, Khaw KT, Riboli E, Grip O, Lindgren S, Hallmans G, Karling P, Clavel-Chapelon F, Bergman MM, Boeing H, Kaaks R, Katzke VA, Palli D, Masala G, Jantchou P, Boutron-Ruault MC

Background: Specific nutrients or foods have been inconsistently associated with ulcerative colitis (UC) or Crohn's disease (CD) risks. Thus, we investigated associations between diet as a whole, as dietary patterns, and UC and CD risks. Methods: Within the prospective EPIC (European Prospective Investigation into Cancer) study, we set up a nested matched case-control study among 366,351 participants with inflammatory bowel disease data, including 256 incident cases of UC and 117 of CD, and... Abstract

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, Volume 106, Issue 2, 1 1 2016, Pages 129-130 The UCT class of 2000 reunion. Diab P, Dramowski A, van Schaik N

Abstract

Cited 14 times since 2016 (1.4 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 24, Issue 2, 1 1 2016, Pages 127-133 The extent of the raphe in bicuspid aortic valves is associated with aortic regurgitation and aortic root dilatation. Koenraadt WM, Grewal N, Gaidoukevitch OY, DeRuiter MC, Gittenberger-de Groot AC, Bartelings MM, Holman ER, Klautz RJ, Schalij MJ, Jongbloed MR

Background: The clinical course of bicuspid aortic valves (BAVs) is variable. Data on predictors of aortopathy and valvular dysfunction mainly focus on valve morphology. Aim: To determine whether the presence and extent of the raphe (fusion site of valve leaflets) is associated with the degree of aortopathy and valvular dysfunction in patients with isolated BAV and associated aortic coarctation (CoA). Methods: Valve morphology and aortic dimensions of 255 BAV patients were evaluated retrospectiv... Abstract

Cited 22 times since 2016 (2.2 per year) source: EuropePMC

Medical education, Volume 50, Issue 2, 1 1 2016, Pages 181-188 Does source matter? Nurses' and Physicians' perceptions of interprofessional feedback. van Schaik SM, O'Sullivan PS, Eva KW, Irby DM, Regehr G

Objective: Receptiveness to interprofessional feedback, which is important for optimal collaboration, may be influenced by 'in-group or out-group' categorisation, as suggested by social identity theory. We used an experimental design to explore how nurses and resident physicians perceive feedback from people within and outside their own professional group. Methods: Paediatric residents and nurses participated in a simulation-based team exercise. Two nurses and two physicians wrote anon... Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 24, Issue 2, 1 1 2016, Pages 154-155 An anomalous left coronary artery with a malignant course: coronary angiography and myocardial perfusion imaging with computed tomography. de Graaf MA, van Rosendael AR, Kroft LJ, Vliegen HW, Hazekamp MG, Bax JJ, Scholte AJ

Abstract

Cited 9 times since 2016 (0.9 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 24, Issue 2, 1 1 2016, Pages 143-151 Outcome of stand-alone thoracoscopic epicardial left atrial posterior box isolation with bipolar radiofrequency energy for longstanding persistent atrial fibrillation. Compier MG, Braun J, Tjon A, Zeppenfeld K, Klautz RJ, Schalij MJ, Trines SA

Introduction: Catheter ablation of longstanding (> 1 year) persistent atrial fibrillation (AF) is associated with poor outcome. This might be due to remodelling and fibrosis formation, mainly located in the posterior left atrial (LA) wall. Therefore, we adopted a thoracoscopic epicardial box isolation of the posterior left atrium using bipolar RF energy with intraoperative testing of conduction block. Methods and results: Bilateral thoracoscopic box isolation was performed with a bipolar RF c... Abstract

Cited 138 times since 2016 (14.1 per year) source: EuropePMC

Nature communications, Volume 7, 1 1 2016, Pages 10494 Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradha

Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency and severe obesity, no common loci regulating circulating leptin levels have been uncovered. Therefore, we performed a genome-wide association study (GWAS) of circulating leptin levels from 32,161 individuals and followed up loci reaching P Abstract