Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Volume 38, Issue 7, 1 1 2024, Pages e23579 Effects of repeated weight cycling on non-alcoholic steatohepatitis in diet-induced obese mice. Inia JA, de Jong JCBC, Keijzer N, Menke AL, Princen HMG, Jukema JW, van den Hoek AM
Lifestyle interventions remain the treatment of choice for patients with obesity and metabolic complications, yet are difficult to maintain and often lead to cycles of weight loss and regain (weight cycling). Literature on weight cycling remains controversial and we therefore investigated the association between weight cycling and metabolic complications using preexistent obese mice. Ldlr-/-.Leiden mice received a high-fat diet (HFD) for 20 weeks to induce obesity. Subsequently, weight-cycled mi... Abstract
Cited 14 times since 2024 (10.2 per year) source: EuropePMC
European journal of heart failure, Volume 26, Issue 4, 1 1 2024, Pages 1078-1089 Interatrial shunt therapy in advanced heart failure: Outcomes from the open-label cohort of the RELIEVE-HF trial. Rodés-Cabau J, Lindenfeld J, Abraham WT, Zile MR, Kar S, Bayés-Genís A, Eigler N, Holcomb R, Núñez J, Lee E, Perl ML, Moravsky G, Pfeiffer M, Boehmer J, Gorcsan J, Bax JJ, Anker S, Stone GW
Aims: Heart failure (HF) outcomes remain poor despite optimal guideline-directed medical therapy (GDMT). We assessed safety, effectiveness, and transthoracic echocardiographic (TTE) outcomes during the 12 months after Ventura shunt implantation in the RELIEVE-HF open-label roll-in cohort. Methods and results: Eligibility required symptomatic HF despite optimal GDMT with ≥1 HF hospitalization in the prior year or elevated natriuretic peptides. The safety endpoint was device-related major adverse... Abstract
The lancet. Gastroenterology & hepatology, Volume 9, Issue 4, 1 1 2024, Pages 293-294 Gluten and non-coeliac gluten sensitivity: the nocebo effect and future avenues - Authors' reply. de Graaf MCG, Keszthelyi D, Brouns FJPH, Dye L, Jonkers DMAE, all authors
Cited 2 times since 2024 (1.5 per year) source: EuropePMC
Radiology. Cardiothoracic imaging, Volume 6, Issue 2, 1 1 2024, Pages e220197 Impact of Smoking on Coronary Volume-to-Myocardial Mass Ratio: An ADVANCE Registry Substudy. Holmes KR, Gulsin GS, Fairbairn TA, Hurwitz-Koweek L, Matsuo H, Nørgaard BL, Jensen JM, Sand NR, Nieman K, Bax JJ, Pontone G, Chinnaiyan KM, Rabbat MG, Amano T, Kawasaki T, Akasaka T, Kitabata H, Rogers C, Patel MR, Payne GW, Leipsic JA, Sellers SL
Purpose To examine the relationship between smoking status and coronary volume-to-myocardial mass ratio (V/M) among individuals with coronary artery disease (CAD) undergoing CT fractional flow reserve (CT-FFR) analysis. Materials and Methods In this secondary analysis, participants from the ADVANCE registry evaluated for suspected CAD from July 15, 2015, to October 20, 2017, who were found to have coronary stenosis of 30% or greater at coronary CT angiography (CCTA) were included if they had kno... Abstract
Cited 3 times since 2024 (2.2 per year) source: EuropePMC
JAMA network open, Volume 7, Issue 4, 1 1 2024, Pages e246556 Nationwide Association of Surgical Performance of Minimally Invasive Esophagectomy With Patient Outcomes. Ketel MHM, Klarenbeek BR, Abma I, Belgers EHJ, Coene PLO, Dekker JWT, van Duijvendijk P, Emous M, Gisbertz SS, Haveman JW, Heisterkamp J, Nieuwenhuijzen GAP, Ruurda JP, van Sandick JW, van der Sluis PC, van Det MJ, van Esser S, Law S, de Steur WO, Sosef MN, Wijnhoven B, Hannink G, Rosman C, van Workum F, MIE-CAT Netherlands Collaborative Group
Importance: Suboptimal surgical performance is hypothesized to be associated with less favorable patient outcomes in minimally invasive esophagectomy (MIE). Establishing this association may lead to programs that promote better surgical performance of MIE and improve patient outcomes. Objective: To investigate associations between surgical performance and postoperative outcomes after MIE. Design, setting, and participants: In this nationwide cohort study of 15 Dutch hospitals that perform more t... Abstract
IEEE transactions on biomedical circuits and systems, Volume 18, Issue 2, 1 1 2024, Pages 423-437 Tau-Cell-Based Analog Silicon Retina With Spatio- Temporal Filtering and Contrast Gain Control. Philip P, Jainwal K, van Schaik A, Thakur CS
Developing precise artificial retinas is crucial because they hold the potential to restore vision, improve visual prosthetics, and enhance computer vision systems. Emulating the luminance and contrast adaption features of the retina is essential to improve visual perception and efficiency to provide an environment realistic representation to the user. In this article, we introduce an artificial retina model that leverages its potent adaptation to luminance and contrast to enhance vision sensing... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, Volume 30, Issue 7, 28 4 2024, Pages 930-936 Intradermal delivery of the third dose of the mRNA-1273 SARS-CoV-2 vaccine: safety and immunogenicity of a fractional booster dose. Roozen GVT, Prins MLM, Prins C, Janse JJ, de Gruyter HLM, Pothast CR, Huisman W, Koopman JPR, Lamers OAC, Kuijer M, Myeni SK, van Binnendijk RS, Hartog GD, Heemskerk MHM, Jochems SP, Feltkamp MCW, Kikkert M, Rosendaal FR, Roestenberg M, Visser LG, Roukens AHE
Objectives: The aim of this study was to assess the safety and immunogenicity of a dose-sparing fractional intradermal (ID) booster strategy with the mRNA-1273 COVID-19 vaccine. Methods: COVID-19 naive adults aged 18-30 years were recruited from a previous study on primary vaccination regimens that compared 20 μg ID vaccinations with 100 μg intramuscular (IM) vaccinations with mRNA-1273 as the primary vaccination series. Participants previously immunized with ID regimens were randomly assigned (... Abstract
Cited 4 times since 2024 (2.9 per year) source: EuropePMC
The American journal of cardiology, Volume 221, 28 4 2024, Pages 37-43 Association of Left Atrial Appendage Morphology and Function With Stroke and Transient Ischemic Attack in Atrial Fibrillation Patients. Simon J, Smit JM, El Mahdiui M, Száraz L, van Rosendael AR, Zsarnóczay E, Nagy AI, Gellér L, van der Geest RJ, Bax JJ, Maurovich-Horvat P, Merkely B
We aimed to correlate left atrial appendage (LAA) structure and function with the history of stroke/transient ischemic attack (TIA) in patients with atrial fibrillation (AF). We analyzed the data of 649 patients with AF who were scheduled for catheter ablation. Patients underwent cardiac computed tomography and transesophageal echocardiography before ablation. The LAA morphologies depicted by cardiac computed tomography were categorized into 4 groups: cauliflower, chicken wing, swan, and windsoc... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Frontiers in neuroscience, Volume 18, 28 4 2024, Pages 1335422 Optimizing event-based neural networks on digital neuromorphic architecture: a comprehensive design space exploration. Xu Y, Shidqi K, van Schaik GJ, Bilgic R, Dobrita A, Wang S, Meijer R, Nembhani P, Arjmand C, Martinello P, Gebregiorgis A, Hamdioui S, Detterer P, Traferro S, Konijnenburg M, Vadivel K, Sifalakis M, Tang G, Yousefzadeh A
Neuromorphic processors promise low-latency and energy-efficient processing by adopting novel brain-inspired design methodologies. Yet, current neuromorphic solutions still struggle to rival conventional deep learning accelerators' performance and area efficiency in practical applications. Event-driven data-flow processing and near/in-memory computing are the two dominant design trends of neuromorphic processors. However, there remain challenges in reducing the overhead of event-driven proc... Abstract
Cited 50 times since 2024 (35.9 per year) source: EuropePMC
The lancet. Diabetes & endocrinology, Volume 12, Issue 5, 27 4 2024, Pages 306-319 Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis. Cholesterol Treatment Trialists’ (CTT) Collaboration Electronic address: ctt@ndphoxacuk, Cholesterol Treatment Trialists’ (CTT) Collaboration
Background: Previous meta-analyses of summary data from randomised controlled trials have shown that statin therapy increases the risk of diabetes, but less is known about the size or timing of this effect, or who is at greatest risk. We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy. Methods: We conducted a meta-analysis of individual participant data from randomised controlled tri... Abstract
Pediatric radiology, Volume 54, Issue 5, 27 4 2024, Pages 859-861 CT, MR, and isotope data of a mummified child from Zagreb Cathedral, Croatia: giving voice to the past through imaging. Van Schaik K, Prenc M, Tomorad M, Štimac I, Novak M, Eppenberger P, Cavka M
Cited 14 times since 2024 (10 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 83, Issue 15, 25 4 2024, Pages 1403-1414 Effect of Sodium-Glucose Cotransporter 2 Inhibitors in Adults With Congenital Heart Disease. Neijenhuis RML, MacDonald ST, Zemrak F, Mertens BJA, Dinsdale A, Hunter A, Walker NL, Swan L, Reddy S, Rotmans JI, Jukema JW, Jongbloed MRM, Veldtman GR, Egorova AD
Background: Heart failure (HF) is the principal cause of morbidity and mortality in adults with congenital heart disease (ACHD). Robust evidence-based treatment options are lacking. Objectives: This study aims to evaluate the safety, tolerability, and short-term HF-related effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in a real-world ACHD population. Methods: All patients with ACHD treated with SGLT2i in 4 European ACHD centers were included in this retrospective study. Data were... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Simulation in healthcare : journal of the Society for Simulation in Healthcare, Volume 20, Issue 1, 25 4 2024, Pages 33-41 A Scoping Review of Interprofessional Simulation-Based Team Training Programs. Bochatay N, Ju M, O'Brien BC, van Schaik SM
Summary statement: Interprofessional simulation-based team training (ISBTT) is promoted as a strategy to improve collaboration in healthcare, and the literature documents benefits on teamwork and patient safety. Teamwork training in healthcare is traditionally grounded in crisis resource management (CRM), but it is less clear whether ISBTT programs explicitly take the interprofessional context into account, with complex team dynamics related to hierarchy and power. This scoping review examined k... Abstract
Precision radiation oncology, Volume 8, Issue 1, 21 3 2024, Pages 47-58 Stereotactic radiotherapy: An educational narrative review. Khan AMH, Hashmi SFA, Li B, Shaukat F, Ahmed Y, Alfishawy M, Al-Amri I, Bashir R, Altaf F, Yilmaz S, Khalid J, Mandhari ZA, Pervez N, Rassou SC, Mula-Hussain L
Stereotactic radiotherapy is a term collectively used to describe the radiation treatment techniques that allow for the delivery of highly precise ionizing radiation. It is usually a high dose per session in single or few fractions. This treatment approach has been in medical use for over six decades and has primarily evolved in the last two decades. Many patients benefit from this unique non-conventional radiotherapy approach. Its indications include various malignant, benign and functional pro... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Journal of affective disorders, Volume 355, 21 3 2024, Pages 95-103 Internet-based emotion regulation training aimed at reducing violent revictimization and depressive symptoms in victimized depressed patients: Results of a randomized controlled trial. Christ C, van Schaik DJF, Kikkert MJ, de Waal MM, Dozeman E, Hulstijn HL, Koomen LM, Krah IM, Schut DM, Beekman ATF, Dekker JJM
Background: Depressed patients who have become victim of violence are prone to revictimization. However, no evidence-based interventions aimed at reducing revictimization in this group exist. Methods: This multicenter randomized controlled trial evaluated the effectiveness of an internet-based emotion regulation training (iERT) added to TAU in reducing revictimization, emotion dysregulation, and depressive symptoms in recently victimized, depressed patients compared to TAU alone. Adult outpatien... Abstract
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Volume 50, Issue 6, 19 3 2024, Pages 108278 Staging laparoscopy in gastric cancer patients: From a Dutch nationwide Delphi consensus towards a standardized protocol. van der Sluis K, Guchelaar NAD, Triemstra L, Mathijssen RHJ, Ruurda JP, Wijnhoven BPL, van Sandick JW, Collaborators
Background: Staging laparoscopy is a common diagnostic tool in gastric cancer, but its performance varies widely. The aim of this study was to gain Dutch nationwide consensus regarding the indications for and execution of staging laparoscopy in patients with gastric cancer. Methods: All surgeons in the Netherlands specialized in gastric cancer surgery (n = 52) were asked to participate in a Delphi consensus study. The study involved an initial questionnaire with a 3-point Likert scale, an online... Abstract
Cited 3 times since 2024 (2.1 per year) source: EuropePMC
JTCVS open, Volume 19, 19 3 2024, Pages 68-90 Current definitions of hemodynamic structural valve deterioration after bioprosthetic aortic valve replacement lack consistency. Velders BJJ, Vriesendorp MD, Asch FM, Reardon MJ, Dagenais F, Moront MG, Sabik Iii JF, Groenwold RHH, Klautz RJM
Objective: New echocardiographic definitions have been proposed for hemodynamic structural valve deterioration. We aimed to study their consistency in classifying structural valve deterioration after surgical aortic valve replacement. Methods: Data were used of patients undergoing surgical aortic valve replacement in a multicenter, prospective cohort study with a 5-year follow-up. All patients received the same stented bioprosthesis. Echocardiographic parameters were assessed by an independent c... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 37, Issue 7, 19 3 2024, Pages 666-673 Prognostic Value of Follow-up Measures of Left Ventricular Global Longitudinal Strain in Patients With ST-Segment Elevation Myocardial Infarction. Caunite L, Myagmardorj R, Galloo X, Laenens D, Stassen J, Nabeta T, Yedidya I, Meucci MC, Kuneman JH, van den Hoogen IJ, van Rosendael SE, Wu HW, van den Brand VM, Giuca A, Trusinskis K, van der Bijl P, Bax JJ, Ajmone Marsan N
Introduction: After ST-segment elevation myocardial infarction (STEMI), follow-up imaging is currently recommended only in patients with left ventricular ejection fraction (LVEF) 7% remained independently associated with the end point (hazard ratio, 2.5 [95% CI, 1.5-4.1]; P Abstract
Cited 2 times since 2024 (1.4 per year) source: EuropePMC
Frontiers in cellular and infection microbiology, Volume 14, 19 3 2024, Pages 1282183 Vaccine development: obligate intracellular bacteria new tools, old pathogens: the current state of vaccines against obligate intracellular bacteria. van Schaik EJ, Fratzke AP, Gregory AE, Dumaine JE, Samuel JE
Obligate intracellular bacteria have remained those for which effective vaccines are unavailable, mostly because protection does not solely rely on an antibody response. Effective antibody-based vaccines, however, have been developed against extracellular bacteria pathogens or toxins. Additionally, obligate intracellular bacteria have evolved many mechanisms to subvert the immune response, making vaccine development complex. Much of what we know about protective immunity for these pathogens has... Abstract
Cited 1 times since 2024 (0.7 per year) source: EuropePMC
Clinical pharmacology and therapeutics, Volume 116, Issue 3, 18 3 2024, Pages 690-702 Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort. Mc Laughlin AM, Helland T, Klima F, Koolen SLW, van Schaik RHN, Mathijssen RHJ, Neven P, Swen JJ, Guchelaar HJ, Dalenc F, White-Koning M, Michelet R, Mikus G, Schroth W, Mürdter T, Brauch H, Schwab M, Søiland H, Mellgren G, Thomas F, Kloft C, Hertz DL, CYP2D6 Endoxifen Percentage Activity Model (CEPAM) Consortium
Tamoxifen is widely used in patients with hormone receptor-positive breast cancer. The polymorphic enzyme CYP2D6 is primarily responsible for metabolic activation of tamoxifen, resulting in substantial interindividual variability of plasma concentrations of its most important metabolite, Z-endoxifen. The Z-endoxifen concentration thresholds below which tamoxifen treatment is less efficacious have been proposed but not validated, and prospective trials of individualized tamoxifen treatment to ach... Abstract