Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9543 results
Cited 28 times since 2009 (1.7 per year) source: EuropePMC
Pharmacogenomics, Volume 10, Issue 11, 1 1 2009, Pages 1743-1751 Common genetic variation in the ABCB1 gene is associated with the cholesterol-lowering effect of simvastatin in males. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH
Aims: The cholesterol-lowering drug simvastatin is a substrate for P-glycoprotein (P-gp). P-gp, encoded by ABCB1, is an efflux transporter and genetic variation in ABCB1 is associated with drug levels and response. We examined the Rotterdam Study, which is a population-based cohort study of people aged 55 years and older, to see whether the C1236T, G2677T/A and C3435T polymorphisms and haplotypes in the ABCB1 gene are associated with the total cholesterol and low-density lipoprotein cholesterol-... Abstract
Cited 28 times since 2009 (1.7 per year) source: EuropePMC
Journal of experimental psychology. Learning, memory, and cognition, Volume 35, Issue 6, 1 1 2009, Pages 1487-1505 Exaggerated risk: prospect theory and probability weighting in risky choice. Kusev P, van Schaik P, Ayton P, Dent J, Chater N
In 5 experiments, we studied precautionary decisions in which participants decided whether or not to buy insurance with specified cost against an undesirable event with specified probability and cost. We compared the risks taken for precautionary decisions with those taken for equivalent monetary gambles. Fitting these data to Tversky and Kahneman's (1992) prospect theory, we found that the weighting function required to model precautionary decisions differed from that required for monetary... Abstract
Cited 123 times since 2009 (7.7 per year) source: EuropePMC
Future microbiology, Volume 4, Issue 9, 1 1 2009, Pages 1125-1135 Transition of Enterococcus faecium from commensal organism to nosocomial pathogen. Willems RJ, van Schaik W
The Gram-positive species Enterococcus faecium has long been thought of as a harmless commensal of the mammalian GI tract. In the last two decades, however, E. faecium has become an important cause of nosocomial bacteremias. These infections are often difficult to treat owing to the resistance of E. faecium to a large number of antibiotics. In this article, we review the recent transition of E. faecium from commensal to nosocomial pathogen. We focus on population biology-based studies, which sug... Abstract
Cited 29 times since 2009 (1.8 per year) source: EuropePMC
American heart journal, Volume 158, Issue 5, 1 1 2009, Pages 860-866 Low- and high-density lipoprotein cholesterol goal attainment in dyslipidemic women: The Lipid Treatment Assessment Project (L-TAP) 2. Santos RD, Waters DD, Tarasenko L, Messig M, Jukema JW, Ferrières J, Verdejo J, Chiang CW, L-TAP 2 Investigators
Background: Differences between women and men have been documented for both diagnostic testing and treatment in cardiology. This analysis evaluates whether low-density lipoprotein cholesterol (LDL-C) success rates according to current guidelines and high-density lipoprotein cholesterol (HDL-C) levels differ by gender in the L-TAP 2 population. Methods: Patients aged > or =20 years with dyslipidemia on stable lipid-lowering therapy were assessed in 9 countries between September 2006 and April... Abstract
Cited 23 times since 2009 (1.4 per year) source: EuropePMC
American heart journal, Volume 158, Issue 5, 1 1 2009, Pages 769-776 Cardiac resynchronization therapy in patients with ischemic versus non-ischemic heart failure: Differential effect of optimizing interventricular pacing interval. Marsan NA, Bleeker GB, Van Bommel RJ, Borleffs C, Bertini M, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Whether sequential biventricular pacing provides substantial benefits over conventional simultaneous stimulation remains unclear, particularly regarding the differences between ischemic and non-ischemic patients. The purpose of this study was to evaluate the acute effect of interventricular pacing interval (V-V) optimization on left ventricular (LV) systolic performance and dyssynchrony in ischemic versus non-ischemic patients. Methods: Sixty-nine consecutive patients underwent cardi... Abstract
Cited 9 times since 2009 (0.6 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 16, Issue 6, 1 1 2009, Pages 970-980 The value of multi-slice-computed tomography coronary angiography for risk stratification. van Werkhoven JM, Bax JJ, Nucifora G, Jukema JW, Kroft LJ, de Roos A, Schuijf JD
Multi-slice-computed tomography coronary angiography (CTA) provides direct non-invasive anatomic assessment of the coronary arteries allowing for early identification of coronary artery disease (CAD). This information is useful for diagnosis of CAD, particularly the rule out of CAD. In addition, early identification of CAD with CTA may also be useful for risk stratification. The purpose of this review is to provide an overview of the current literature on the prognostic value of CTA and to discu... Abstract
Cited 8 times since 2009 (0.5 per year) source: EuropePMC
Critical care medicine, Volume 37, Issue 11, 1 1 2009, Pages 2962-2967 Continuous right ventricular volumetry by fast-response thermodilution during right ventricular ischemia: head-to-head comparison with conductance catheter measurements. Hein M, Roehl AB, Baumert JH, Rossaint R, Steendijk P
Objective: To evaluate the accuracy of right ventricular ejection fraction and right ventricular end-diastolic volume obtained by volumetric pulmonary artery catheter, using the conductance catheter as reference method. Design: Prospective, comparative study. Setting: Research laboratory of a university hospital. Subjects: Seven young female German landrace pigs. Interventions: Ligation of the distal right coronary artery to induce temporary acute ischemia. Measurements and main results: Right v... Abstract
Cited 13 times since 2009 (0.8 per year) source: EuropePMC
Journal of biomedical optics, Volume 14, Issue 6, 1 1 2009, Pages 064038 Motion-gated acquisition for in vivo optical imaging. Gioux S, Ashitate Y, Hutteman M, Frangioni JV
Wide-field continuous wave fluorescence imaging, fluorescence lifetime imaging, frequency domain photon migration, and spatially modulated imaging have the potential to provide quantitative measurements in vivo. However, most of these techniques have not yet been successfully translated to the clinic due to challenging environmental constraints. In many circumstances, cardiac and respiratory motion greatly impair image quality and/or quantitative processing. To address this fundamental problem,... Abstract
Cited 122 times since 2009 (7.6 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 2, Issue 11, 1 1 2009, Pages 1245-1252 Quantification of functional mitral regurgitation by real-time 3D echocardiography: comparison with 3D velocity-encoded cardiac magnetic resonance. Marsan NA, Westenberg JJ, Ypenburg C, Delgado V, van Bommel RJ, Roes SD, Nucifora G, van der Geest RJ, de Roos A, Reiber JC, Schalij MJ, Bax JJ
Objectives: The aim of this study was to evaluate feasibility and accuracy of real-time 3-dimensional (3D) echocardiography for quantification of mitral regurgitation (MR), in a head-to-head comparison with velocity-encoded cardiac magnetic resonance (VE-CMR). Background: Accurate grading of MR severity is crucial for appropriate patient management but remains challenging. VE-CMR with 3D three-directional acquisition has been recently proposed as the reference method. Methods: A total of 64 pati... Abstract
Cited 4 times since 2009 (0.2 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 5, Issue 5, 1 1 2009, Pages 565-572 Impact of sirolimus-eluting stent implantation compared to bare-metal stent implantation for acute myocardial infarction on coronary plaque composition at nine months follow-up: a Virtual Histology intravascular ultrasound analysis. Results from the Leiden MISSION! intervention study. Atary JZ, Bergheanu SC, van der Hoeven BL, Atsma DE, Bootsma M, van der Kley F, Zeppenfeld K, Jukema JW, Schalij MJ
Aims: To evaluate effects of sirolimus-eluting stents (SES) compared to bare-metal stents (BMS) at stent edges in patients with acute myocardial infarction (AMI). Methods and results: Clinical, angiographic, intravascular ultrasound (lVUS) and virtual histology (VH)-IVUS results were obtained and analysed in 20 SES and 20 BMS AMI patients at the index procedure and at nine months follow-up. Quantitative angiography and IVUS showed a trend toward decreases in mean lumen diameter, vessel volume, m... Abstract
Cited 79 times since 2009 (4.9 per year) source: EuropePMC
The American journal of cardiology, Volume 104, Issue 9, 1 1 2009, Pages 1229-1234 Timing of noncardiac surgery after coronary artery stenting with bare metal or drug-eluting stents. van Kuijk JP, Flu WJ, Schouten O, Hoeks SE, Schenkeveld L, de Jaegere PP, Bax JJ, van Domburg RT, Serruys PW, Poldermans D
The current guidelines have recommended postponing noncardiac surgery (NCS) for > or =6 weeks after bare metal stent (BMS) placement and for > or =1 year after drug-eluting stent (DES) placement. However, much debate has ensued about these intervals. The aim of the present study was to assess the influence of different intervals between stenting and NCS and the use of dual antiplatelet therapy on the occurrence of perioperative major adverse cardiac events (MACEs). We identified 550 patien... Abstract
Cited 130 times since 2009 (8.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 54, Issue 19, 1 1 2009, Pages 1770-1777 Prognostic value of myocardial infarct size and contractile reserve using magnetic resonance imaging. Kelle S, Roes SD, Klein C, Kokocinski T, de Roos A, Fleck E, Bax JJ, Nagel E
Objectives: Our aim was to assess the predictive value of myocardial infarct size assessed with late gadolinium-enhanced (LGE) magnetic resonance imaging (MRI) in medically treated patients with chronic myocardial infarction relative to contractile reserve on low-dose dobutamine magnetic resonance (DSMR) for long-term event-free survival. Background: Information on the relative merits of scar tissue and contractile reserve to predict long-term prognosis in patients with chronic myocardial infarc... Abstract
Cited 11 times since 2009 (0.7 per year) source: EuropePMC
Anesthesia and analgesia, Volume 109, Issue 5, 1 1 2009, Pages 1403-1408 The interrelationship between preoperative anemia and N-terminal pro-B-type natriuretic peptide: the effect on predicting postoperative cardiac outcome in vascular surgery patients. Goei D, Flu WJ, Hoeks SE, Galal W, Dunkelgrun M, Boersma E, Kuijper R, van Kuijk JP, Winkel TA, Schouten O, Bax JJ, Poldermans D
Introduction: N-terminal pro-B-type natriuretic peptide (NT-proBNP) predicts adverse cardiac outcome in patients undergoing vascular surgery. However, several conditions might influence this prognostic value, including anemia. In this study, we evaluated whether anemia confounds the prognostic value of NT-proBNP for predicting cardiac events in patients undergoing vascular surgery. Methods: A detailed cardiac history, resting echocardiography, and hemoglobin and NT-proBNP levels were obtained in... Abstract
Cited 3 times since 2009 (0.2 per year) source: EuropePMC
Current problems in cardiology, Volume 34, Issue 11, 1 1 2009, Pages 539-577 How to identify the asymptomatic high-risk patient? Schuijf JD, Achenbach S, Zoghbi WA, Boersma E, Raggi P, Weber M, Nagel E, Narula J, Wackers FJ, Poldermans D, Bax JJ
Worldwide, cardiovascular diseases are among the leading causes of mortality and morbidity with ever-increasing prevalence. Early targeted initiation of preventive measures would be of great benefit and can provide a major opportunity in reducing mortality and morbidity. To this end, accurate identification of individuals who are still asymptomatic but at elevated risk is essential. However, traditional risk assessment fails to recognize a substantial proportion of patients at high risk while a... Abstract
Cited 19 times since 2009 (1.2 per year) source: EuropePMC
Coronary artery disease, Volume 20, Issue 7, 1 1 2009, Pages 462-466 Value of contrast echocardiography for left ventricular thrombus detection postinfarction and impact on antithrombotic therapy. Siebelink HM, Scholte AJ, Van de Veire NR, Holman ER, Nucifora G, van der Wall EE, Bax JJ
Introduction: Conventional echocardiography is often inconclusive for the presence or the absence of left ventricular (LV) thrombus. Contrast echocardiography could have additional diagnostic and therapeutic significance. This analysis investigated the value of contrast echocardiography for LV thrombus detection in patients postinfarction and the impact on choice of antithrombotic therapy. Methods: From a cohort of 991 patients undergoing routine echocardiography postinfarction, 156 patients who... Abstract
Cited 25 times since 2009 (1.6 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 95, Issue 22, 1 1 2009, Pages 1881-1890 Real-time three dimensional echocardiography: current and future clinical applications. Marsan NA, Tops LF, Nihoyannopoulos P, Holman ER, Bax JJ
Cited 32 times since 2009 (2 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 11 Suppl 5, 1 1 2009, Pages v46-57 Why, how and when do we need to optimize the setting of cardiac resynchronization therapy? Bertini M, Delgado V, Bax JJ, Van de Veire NR
Current cardiac resynchronization therapy (CRT) devices allow manipulation of the atrioventricular (AV) and interventricular (VV) timings in order to maximize the left ventricular (LV) performance. Multiple echocardiographic and non-echocardiographic methods have been proposed to optimize AV and VV intervals but no consensus has been reached on which methodology should preferably be used. Furthermore, different physiologic conditions, such as rest and exercise, may markedly change LV loading con... Abstract
Cited 78 times since 2009 (4.9 per year) source: EuropePMC
Diabetes care, Volume 32, Issue 11, 1 1 2009, Pages 2094-2098 Prediction of coronary heart disease risk in a general, pre-diabetic, and diabetic population during 10 years of follow-up: accuracy of the Framingham, SCORE, and UKPDS risk functions: The Hoorn Study. van der Heijden AA, Ortegon MM, Niessen LW, Nijpels G, Dekker JM
Objective: To test the validity of the Framingham, Systematic Coronary Risk Evaluation (SCORE), and UK Prospective Diabetes Study (UKPDS) risk function in the prediction of risk of coronary heart disease (CHD) in populations with normal glucose tolerance (NGT), intermediate hyperglycemia, and type 2 diabetes. Research design and methods: Calibration and discrimination of the three prediction models were tested using prospective data for 1,482 Caucasian men and women, 50-75 years of age, who part... Abstract
Cited 17 times since 2009 (1.1 per year) source: EuropePMC
Molecular phylogenetics and evolution, Volume 54, Issue 2, 28 4 2009, Pages 336-343 Preliminary insight into the age and origin of the Labeobarbus fish species flock from Lake Tana (Ethiopia) using the mtDNA cytochrome b gene. de Graaf M, Megens HJ, Samallo J, Sibbing F
The high diversity of Cyprinid fish in Ethiopia's Lake Tana appears to be an example of ecological differentiation and assortative mating leading to rapid sympatric speciation. Lake Tana's Labeobarbus species flock consists of 15 morphological and ecological distinct species. This is the first attempt to determine the age and origin and inter-species relationships of Lake Tana's Labeobarbus species using the mtDNA cytochrome b gene. Analysis of cytchrome b sequences shows that Lak... Abstract
Cited 32 times since 2009 (2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 3, 28 4 2009, Pages 213-219 Single-beat estimation of the left ventricular end-diastolic pressure-volume relationship in patients with heart failure. Ten Brinke EA, Burkhoff D, Klautz RJ, Tschöpe C, Schalij MJ, Bax JJ, van der Wall EE, Dion RA, Steendijk P
Aims: To test a method to predict the end-diastolic pressure-volume relationship (EDPVR) from a single beat in patients with heart failure. Methods and results: Patients (New York Heart Association class III-IV) scheduled for mitral annuloplasty (n=9) or ventricular restoration (n=10) and patients with normal left ventricular function undergoing coronary artery bypass grafting (n=12) were instrumented with pressure-conductance catheters to measure pressure-volume loops before and after surgery.... Abstract