Research

Publications

Below you can find a list of our published research.

9543 results

Cited 162 times since 2007 (9 per year) source: EuropePMC

Proceedings of the National Academy of Sciences of the United States of America, Volume 104, Issue 50, 5 1 2007, Pages 19762-19766 Other-regarding preferences in a non-human primate: common marmosets provision food altruistically. Burkart JM, Fehr E, Efferson C, van Schaik CP

Human cooperation is unparalleled in the animal world and rests on an altruistic concern for the welfare of genetically unrelated strangers. The evolutionary roots of human altruism, however, remain poorly understood. Recent evidence suggests a discontinuity between humans and other primates because individual chimpanzees do not spontaneously provide food to other group members, indicating a lack of concern for their welfare. Here, we demonstrate that common marmoset monkeys (Callithrix jacchus)... Abstract

Cited 13 times since 2007 (0.7 per year) source: EuropePMC

Radiology, Volume 246, Issue 2, 4 1 2007, Pages 394-400 MR imaging of right ventricular function after the Ross procedure for aortic valve replacement: initial experience. Grotenhuis HB, de Roos A, Ottenkamp J, Schoof PH, Vliegen HW, Kroft LJ

Purpose: To prospectively assess right ventricular (RV) function after the Ross procedure by using magnetic resonance (MR) imaging. Materials and methods: The local ethics committee approved the study and informed consent was obtained from all participants prior to enrollment in the study. Seventeen patients (15 male, two female; mean age +/- standard deviation, 19 years +/- 3.9; imaging performed 8.3 years after surgery +/- 3.2) and 17 matched controls (15 male, two female; mean age +/- standar... Abstract

Cited 2 times since 2007 (0.1 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 50, Issue 25, 1 1 2007, Pages 2421-2430 Highlights of the 2007 scientific sessions of the European Society of Cardiology Vienna, Austria, September 1-5, 2007. Kristensen SD, Baumgartner H, Drexler H, Eeckhout E, Filippatos G, Gitt AK, Linde C, Pierard LA, Poldermans D, Schunkert H, Sipido KR, van der Wall EE, Fox K, Bax JJ, European Society of Cardiology

Abstract

Cited 63 times since 2007 (3.5 per year) source: EuropePMC

Archives of internal medicine, Volume 167, Issue 22, 1 1 2007, Pages 2482-2489 A prognostic risk index for long-term mortality in patients with peripheral arterial disease. Feringa HH, Bax JJ, Hoeks S, van Waning VH, Elhendy A, Karagiannis S, Vidakovic R, Schouten O, Boersma E, Poldermans D

Background: Prognostic information in peripheral arterial disease (PAD) may provide the basis for optimal management strategies at an early stage. This study aimed to develop a prognostic risk index for long-term mortality in patients with PAD. Methods: In a single-center observational cohort study, 2642 patients with an ankle-brachial index of 0.90 or lower were randomly divided into derivation (n = 1332) and validation (n = 1310) cohorts. Cox regression analysis with stepwise backward eliminat... Abstract

Cited 5 times since 2007 (0.3 per year) source: EuropePMC

Coronary artery disease, Volume 18, Issue 8, 1 1 2007, Pages 645-651 Baseline natriuretic peptide levels in relation to myocardial ischemia, troponin T release and heart rate variability in patients undergoing major vascular surgery. Feringa HH, Vidakovic R, Karagiannis SE, de Jonge R, Lindemans J, Goei D, Schouten O, Bax JJ, Poldermans D

Background: This study was conducted to determine the association between baseline N-terminal pro-B-type natriuretic peptide (NT-proBNP) and myocardial ischemia, troponin T release and heart rate variability (HRV) in patients undergoing major vascular surgery. Methods: In a prospective study, 182 vascular surgery patients were evaluated by clinical risk factors, dobutamine stress echocardiography and baseline NT-proBNP levels. Myocardial ischemia was detected by continuous 12-lead electrocardiog... Abstract

Cited 41 times since 2007 (2.3 per year) source: EuropePMC

Current opinion in lipidology, Volume 18, Issue 6, 1 1 2007, Pages 645-649 Opportunities and challenges for mesenchymal stem cell-mediated heart repair. Atsma DE, Fibbe WE, Rabelink TJ

Purpose of review: Mesenchymal stem cells (or multipotent stromal cells) are emerging as a potent cell type for cardiac cell therapy. This review describes the potential of cardiac mesenchymal stem cell therapy, but also highlights some recently discovered less favorable mesenchymal stem cell characteristics. Recent findings: Mesenchymal stem cells exert a beneficial effect on cardiac function upon administration to the ischemic myocardium. The mode of action does not seem to involve differentia... Abstract

Cited 44 times since 2007 (2.4 per year) source: EuropePMC

Clinical orthopaedics and related research, Volume 465, 1 1 2007, Pages 23-32 The 2007 Otto Aufranc Award. Ceramic-on-metal hip arthroplasties: a comparative in vitro and in vivo study. Williams S, Schepers A, Isaac G, Hardaker C, Ingham E, van der Jagt D, Breckon A, Fisher J

The performance of novel ceramic-on-metal bearing couples has been compared with metal-on-metal and ceramic-on-ceramic bearing couples in laboratory and short-term clinical studies. Laboratory studies compared ceramic-on-metal with metal-on-metal and ceramic-on-ceramic bearings with diameters of 28 and 36 mm under standard conditions and under adverse conditions with head loading on the rim of the cup. Clinical studies compared metal ion levels in ceramic-on-metal with metal-on-metal, ceramic-on... Abstract

Cited 45 times since 2007 (2.5 per year) source: EuropePMC

Journal of clinical pharmacology, Volume 47, Issue 12, 1 1 2007, Pages 1555-1569 A randomized, placebo-controlled trial to evaluate the efficacy, safety, and pharmacodynamic interaction of coadministered amlodipine and atorvastatin in 1660 patients with concomitant hypertension and dyslipidemia: the respond trial. Preston RA, Harvey P, Herfert O, Dykstra G, Jukema JW, Sun F, Gillen D

Guidelines stress the importance of the simultaneous management of multiple cardiovascular risk factors. This can in part be achieved by coadministration of lipid-lowering and antihypertensive treatments. Potential pharmacodynamic interaction between drugs should be investigated as part of developing single-pill combinations. The Respond trial assessed whether combining amlodipine to treat hypertension and atorvastatin to treat dyslipidemia affected the action of either monotherapy. A total of 1... Abstract

Cited 23 times since 2007 (1.3 per year) source: EuropePMC

Journal of hypertension, Volume 25, Issue 12, 1 1 2007, Pages 2454-2462 Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice. van der Hoorn JW, Kleemann R, Havekes LM, Kooistra T, Princen HM, Jukema JW

Aim: This study was designed to investigate the effect of the angiotensin II receptor blocker olmesartan alone, or in combination with standard treatment with a statin, pravastatin, on atherosclerosis development in APOE*3Leiden transgenic mice. Methods and results: Four groups of 15 mice received an atherogenic diet alone (plasma cholesterol 17.4 +/- 2.7 mmol/l) or supplemented with either 0.008% (w/w) olmesartan (9.3 mg/kg per day) (plasma cholesterol 16.4 +/- 3.9 mmol/l), 0.03% (w/w) pravasta... Abstract

Clinical nuclear medicine, Volume 32, Issue 12, 1 1 2007, Pages 927-929 Intermittent ST-segment depressions during adenosine stress test. van der Hiel B, Scholte AJ, Stokkel MP

ST-segment depression during adenosine stress testing is usually a 1-time event during or after the test and is often related to ischemia due to severe 3-vessel disease. In this case report we describe a patient with severe 3-vessel disease who had intermittent ST-segment depression on the electrocardiogram during a myocardial perfusion stress test with adenosine. These intermittent ST depressions could be explained by possible adenosine-induced coronary spasm. Abstract

Cited 16 times since 2007 (0.9 per year) source: EuropePMC

Microbiology (Reading, England), Volume 153, Issue Pt 12, 1 1 2007, Pages 4234-4239 The stringent response of Bacillus anthracis contributes to sporulation but not to virulence. van Schaik W, Prigent J, Fouet A

The Gram-positive, spore-forming pathogen Bacillus anthracis is the aetiological agent of anthrax. Its main virulence factors are two toxins and an anti-phagocytic capsule. When B. anthracis is grown in laboratory culture, the highest expression of the anthrax toxin genes occurs during entry into stationary phase, suggesting that nutrient limitation is an environmental cue which induces toxin production. A common bacterial response to starvation is the so-called stringent response, in which the... Abstract

Cited 6 times since 2007 (0.3 per year) source: EuropePMC

IEEE transactions on biomedical circuits and systems, Volume 1, Issue 4, 1 1 2007, Pages 278-288 An address-event vision sensor for multiple transient object detection. Chan V, Jin C, van Schaik A

We present a vision sensor chip designed to detect multiple transient objects - objects that either move or change in light intensity - and output their locations using address-event representation. The sensor uses a novel onset detector to detect transient objects and a dynamically-wired winner-takes-all circuit to group pixels and select the brightest pixel in each object. This paper describes the circuits and also presents measurements that characterize the performance of the sensor chip. Abstract

Cited 28 times since 2007 (1.6 per year) source: EuropePMC

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 48, Issue 12, 1 1 2007, Pages 2001-2010 Nuclear imaging in cardiac resynchronization therapy. Henneman MM, van der Wall EE, Ypenburg C, Bleeker GB, van de Veire NR, Marsan NA, Chen J, Garcia EV, Westenberg JJ, Schalij MJ, Bax JJ

Recently, cardiac resynchronization therapy (CRT) has become implemented in the treatment of patients with severe heart failure. Although the improvement in systolic function after CRT implantation can be considerable, 20%-30% of patients do not respond to CRT. Evidence is accumulating that the presence of left ventricular (LV) dyssynchrony is mandatory for a response to CRT. Since the early 1980s attempts have been made to assess cardiac dyssynchrony with nuclear imaging, and it has been report... Abstract

Cited 6 times since 2007 (0.3 per year) source: EuropePMC

Thrombosis and haemostasis, Volume 98, Issue 6, 1 1 2007, Pages 1323-1328 The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions. Pons D, Monraats PS, de Maat MP, Pires NM, Quax PH, van Vlijmen BJ, Rosendaal FR, Zwinderman AH, Doevendans PA, Waltenberger J, de Winter RJ, Tio RA, Frants RR, van der Laarse A, van der Wall EE, Jukema JW

Since activation of the haemostatic system is an important feature of the wound healing response triggered by arterial injury, variations in genes involved in thrombus formation may play a role in restenosis after percutaneous coronary interventions (PCI). Therefore, our aim was to examine the relationship between polymorphisms that are known to play a role in the haemostatic system and the risk of clinical restenosis in the GENetic DEterminants of Restenosis (GENDER) study, a multicenter prospe... Abstract

Journal of the American College of Cardiology, Volume 50, Issue 24, 26 4 2007, Pages 2336-2343 Highlights of the 2007 scientific sessions of the American Society of Nuclear Cardiology San Diego, California, September 6-9, 2007. Russell RR, Abbott BG, Arrighi JA, Bengel FM, Cohen MC, Garcia EV, Hendel RC, Holly TA, Mieres JH, Shaw LJ, Thomas GS, Thompson RC, Wackers FJ, Bax JJ

Abstract

Cited 42 times since 2007 (2.3 per year) source: EuropePMC

The American journal of cardiology, Volume 101, Issue 1, 26 4 2007, Pages 40-45 Anatomic correlates of a normal perfusion scan using 64-slice computed tomographic coronary angiography. van Werkhoven JM, Schuijf JD, Jukema JW, Kroft LJ, Stokkel MP, Dibbets-Schneider P, Pundziute G, Scholte AJ, van der Wall EE, Bax JJ

Both myocardial perfusion imaging (MPI) and multislice computed tomography (MSCT) are currently used to detect coronary artery disease (CAD). However, MSCT permits early detection of atherosclerosis while myocardial perfusion is still normal. In addition, MPI results can be normal despite the presence of high-risk CAD (left main and balanced 3-vessel CAD). In this study, the range of anatomic findings using MSCT in patients with normal MPI results was evaluated. In 180 patients presenting with c... Abstract

Cited 235 times since 2007 (13.1 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 50, Issue 24, 26 4 2007, Pages 2275-2284 Noninvasive risk assessment early after a myocardial infarction the REFINE study. Exner DV, Kavanagh KM, Slawnych MP, Mitchell LB, Ramadan D, Aggarwal SG, Noullett C, Van Schaik A, Mitchell RT, Shibata MA, Gulamhussein S, McMeekin J, Tymchak W, Schnell G, Gillis AM, Sheldon RS, Fick GH, Duff HJ, REFINE Investigators

Objectives: This study sought to determine whether combined assessment of autonomic tone plus cardiac electrical substrate identifies most patients at risk of serious events after myocardial infarction (MI) and to compare assessment at 2 to 4 weeks versus 10 to 14 weeks after MI. Background: Methods to identify most patients at risk of serious events after MI are required. Methods: Patients (n = 322) with an ejection fraction (EF) Abstract

Cited 33 times since 2007 (1.8 per year) source: EuropePMC

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, Volume 119, Issue 1, 26 4 2007, Pages 33-42 Motor unit number estimation using high-density surface electromyography. van Dijk JP, Blok JH, Lapatki BG, van Schaik IN, Zwarts MJ, Stegeman DF

Objective: To present a motor unit number estimation (MUNE) technique that resolves alternation by means of high-density surface EMG. Methods: High-density surface EMG, using 120 EMG channels simultaneously, is combined with elements of the increment counting technique (ICT) and the multiple-point stimulation technique. Alternation is a major drawback in the ICT. The spatial and temporal information provided by high-density surface EMG support identification and elimination of the effects of alt... Abstract

Cited 3 times since 2007 (0.2 per year) source: EuropePMC

Clinical nutrition (Edinburgh, Scotland), Volume 27, Issue 1, 26 4 2007, Pages 171-172 Presence and functioning of scales and stadiometers in paediatric units. Hutteman M, van der Ende J, Schweizer JJ

Abstract

Journal of cardiovascular electrophysiology, Volume 19, Issue 2, 20 3 2007, Pages 133-135 The role of positron emission tomography in evaluation of alterations in cardiac efficiency after cardiac resynchronization therapy. Ypenburg C, Bax JJ

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