9543 results
Cited 4 times since 2006 (0.2 per year)
source: EuropePMC
BioTechniques,
Volume 41, Issue 6, 1 1 2006, Pages 711-713
Modular and excisable molecular switch for the induction of gene expression by the yeast FLP recombinase.
Holkers M, De Vries AA, Gonçalves MA
Abstract
Cited 10 times since 2006 (0.5 per year)
source: EuropePMC
Genetic epidemiology,
Volume 30, Issue 8, 1 1 2006, Pages 645-651
Simultaneous estimation of gene-gene and gene-environment interactions for numerous loci using double penalized log-likelihood.
Tanck MW, Jukema JW, Zwinderman AH
Many common human diseases are considered to be caused by complex multifactorial processes. For these diseases, it is expected that numerous genetic and environmental factors and, possibly, their interactions play a role. Therefore, simultaneously analyzing the effects of numerous genes and environmental factors is a more realistic approach compared to single gene analyses, but the large number of genes and environmental factors pose a challenge, not in the least due to the limitations created b...
Abstract
Cited 4 times since 2006 (0.2 per year)
source: EuropePMC
Peptides,
Volume 28, Issue 1, 1 1 2006, Pages 94-102
Recombinant production and structural studies of the Aplysia water-borne protein pheromone enticin indicates it has a novel disulfide stabilized fold.
Cummins SF, Xie F, Misra M, Amare A, Jakubowski JA, de Vries MR, Sweedler JV, Nagle GT, Schein CH
Enticin is one of three Aplysia proteins released during egg laying that act in concert with the pheromone attractin to attract other Aplysia and stimulate mating behavior. Whereas the enticin cDNA predicts a 69-residue mature protein, enticin isolated from the albumen gland was found to be posttranslationally processed in vivo by cleavage at Arg(50) residue to generate a smaller 49-residue mature peptide. The Arg(50) cleavage site is conserved in enticin from both Aplysia californica and Aplysi...
Abstract
Cited 39 times since 2006 (2.1 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 132, Issue 6, 1 1 2006, Pages 1426-1432
Degeneration of the pulmonary autograft: an explant study.
Schoof PH, Takkenberg JJ, van Suylen RJ, Zondervan PE, Hazekamp MG, Dion RA, Bogers AJ
Objective: We sought to determine the histologic features of pulmonary autografts explanted after the Ross operation. Methods: Histologic sections of 30 explanted autografts and 8 normal heart valves were compared and semiquantitatively scored by a blinded cardiovascular pathologist. Results: Pulmonary autografts (n = 30) were explanted on average 6.1 +/- 0.6 years (median, 6.6 years; range, 0.1-11.7 years) after the Ross operation (n = 28) or removed at autopsy (n = 2). Twelve (43%) of the pati...
Abstract
Cited 34 times since 2006 (1.8 per year)
source: EuropePMC
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology,
Volume 288, Issue 12, 1 1 2006, Pages 1272-1280
Epicardium-derived cells are important for correct development of the Purkinje fibers in the avian heart.
Eralp I, Lie-Venema H, Bax NA, Wijffels MC, Van Der Laarse A, Deruiter MC, Bogers AJ, Van Den Akker NM, Gourdie RG, Schalij MJ, Poelmann RE, Gittenberger-De Groot AC
During embryonic development, the proepicardial organ (PEO) grows out over the heart surface to form the epicardium. Following epithelial-mesenchymal transformation, epicardium-derived cells (EPDCs) migrate into the heart and contribute to the developing coronary arteries, to the valves, and to the myocardium. The peripheral Purkinje fiber network develops from differentiating cardiomyocytes in the ventricular myocardium. Intrigued by the close spatial relationship between the final destinations...
Abstract
Cited 10 times since 2006 (0.5 per year)
source: EuropePMC
International journal of STD & AIDS,
Volume 17, Issue 12, 1 1 2006, Pages 826-830
Lessons learned from a population-based chlamydia screening pilot.
Götz HM, van Bergen JE, Veldhuijzen IK, Hoebe CJ, Broer J, Coenen AJ, de Groot F, Verhooren MJ, van Schaik DT, Richardus JH
We evaluated process organization and response optimization in a home-based Chlamydia trachomatis (Ct) screening project in the Netherlands among 15- to 29-year-old women and men. The method used was computer-supported data flow, from population sampling to informing participants of the result. A new test kit or a letter reminded non-respondents after six weeks. Fifteen-year olds required parental consent. Urine arrived at the laboratory within 29 days from invitation, and four (1-11) days after...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 14, Issue 12, 1 1 2006, Pages 440-441
CT imaging of the heart.
Schuijf JD, Jukema JW, Bax JJ
Abstract
Cited 9 times since 2006 (0.5 per year)
source: EuropePMC
Journal of the renin-angiotensin-aldosterone system : JRAAS,
Volume 7, Issue 4, 1 1 2006, Pages 225-230
Cardiac aldosterone in subjects with hypertrophic cardiomyopathy.
Chai W, Hoedemaekers Y, van Schaik RH, van Fessem M, Garrelds IM, Saris JJ, Dooijes D, ten Cate FJ, Kofflard MM, Danser AH
Left ventricular (LV) hypertrophy in subjects with hypertrophic cardiomyopathy (HCM) is variable, suggesting a role for modifying factors. Here, we determined whether aldosterone modulates hypertrophy in HCM. Cardiac and/or plasma aldosterone were measured in organ donors and HCM patients. The effect of the aldosterone synthase ( CYP11B2 ) C-344T polymorphism on LV mass index (LVMI) and interventricular septum thickness (IVS) was determined in 79 genetically independent subjects with HCM. Aldost...
Abstract
Cited 176 times since 2006 (9.3 per year)
source: EuropePMC
Biology letters,
Volume 2, Issue 4, 1 1 2006, Pages 557-560
Metabolic costs of brain size evolution.
Isler K, van Schaik CP
In the ongoing discussion about brain evolution in vertebrates, the main interest has shifted from theories focusing on energy balance to theories proposing social or ecological benefits of enhanced intellect. With the availability of a wealth of new data on basal metabolic rate (BMR) and brain size and with the aid of reliable techniques of comparative analysis, we are able to show that in fact energetics is an issue in the maintenance of a relatively large brain, and that brain size is positiv...
Abstract
Cited 41 times since 2006 (2.2 per year)
source: EuropePMC
Anesthesiology,
Volume 105, Issue 6, 1 1 2006, Pages 1135-1146
Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery.
Peeters MY, Prins SA, Knibbe CA, Dejongh J, Mathôt RA, Warris C, van Schaik RH, Tibboel D, Danhof M
Background: Because information on the optimal dose of midazolam for sedation of nonventilated infants after major surgery is scant, a population pharmacokinetic and pharmacodynamic model is developed for this specific group. Methods: Twenty-four of the 53 evaluated infants (aged 3-24 months) admitted to the Pediatric Surgery Intensive Care Unit, who required sedation judged necessary on the basis of the COMFORT-Behavior score and were randomly assigned to receive midazolam, were included in the...
Abstract
Cited 21 times since 2006 (1.1 per year)
source: EuropePMC
Clinical endocrinology,
Volume 65, Issue 6, 1 1 2006, Pages 792-799
Expression of activin and inhibin subunits, receptors and binding proteins in human adrenocortical neoplasms.
Hofland J, Timmerman MA, de Herder WW, van Schaik RH, de Krijger RR, de Jong FH
Objective: The growth and differentiation factors activin and inhibin can affect tumour formation and steroid production in the adrenal cortex. These factors bind to type I (Alk-4), type II (ActRIIA, ActRIIB) and type III (betaglycan) receptors or to the activin-binding protein follistatin. Expression of these activin-related mRNAs was measured in different types of adrenocortical tissues and tumours to study the relationship with tumorigenesis. Design: Quantitative expression of activin-related...
Abstract
Cited 36 times since 2006 (1.9 per year)
source: EuropePMC
Neuromuscular disorders : NMD,
Volume 17, Issue 1, 1 1 2006, Pages 33-37
The Dutch neuromuscular database CRAMP (Computer Registry of All Myopathies and Polyneuropathies): development and preliminary data.
van Engelen BG, van Veenendaal H, van Doorn PA, Faber CG, van der Hoeven JH, Janssen NG, Notermans NC, van Schaik IN, Visser LH, Verschuuren JJ
Each of the various neuromuscular diseases is rare. Consequently, solid epidemiological data are not available and it is often difficult to find sufficient patients for studies. For this reason, the Dutch neuromuscular database, CRAMP (Computer Registry of All Myopathies and Polyneuropathies), was developed in 2004 by the Dutch Neuromuscular Research Support Centre, to store information on patient characteristics and diagnoses (based on Rowland and McLeod's classification) in a uniform and...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 14, Issue 12, 1 1 2006, Pages 417-419
Sudden cardiac death: time to make a difference: Pro ICD.
Schalij MJ, van Erven L
Abstract
Cited 8 times since 2006 (0.4 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 18, Issue 2, 29 5 2006, Pages 222-225
Triplane tissue Doppler imaging to evaluate mechanical dyssynchrony before and after cardiac resynchronization in a patient with congenitally corrected transposition of the great arteries.
Van de Veire NR, Blom NA, Holman ER, Schalij MJ, Bax JJ
We report the case of a 13-year-old girl with congenitally corrected transposition of the great arteries. Since the implantation of a conventional pacemaker for acquired complete atrioventricular block, the patient experienced increased heart failure symptoms. Using triplane tissue Doppler imaging, significant intraventricular dyssynchrony induced by unilateral pacing and associated with diminished exercise capacity was demonstrated. A biventricular pacemaker was successfully implanted transveno...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 12, 28 4 2006, Pages 2564-2574
Highlights of the 2006 scientific sessions of the European Society of Cardiology: Barcelona, Spain, September 2-5, 2006.
Bax JJ, De Bruyne B, Gitt AK, Kristensen S, Linde C, Poldermans D, Pinto FJ, Ponikowski P, Prendergast BD, Abagiti-Rosei E, Smith SC, Sipido KR, van der Wall EE, Tendera M, Komajda M, European Society of Cardiology
Abstract
Cited 305 times since 2006 (16.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 12, 28 4 2006, Pages 2508-2514
Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging.
Schuijf JD, Wijns W, Jukema JW, Atsma DE, de Roos A, Lamb HJ, Stokkel MP, Dibbets-Schneider P, Decramer I, De Bondt P, van der Wall EE, Vanhoenacker PK, Bax JJ
Objectives: The aim of this study was to perform a head-to-head comparison between multi-slice computed tomography (MSCT) and myocardial perfusion imaging (MPI) in patients with an intermediate likelihood of coronary artery disease (CAD) and to compare non-invasive findings to invasive coronary angiography. Background: Multi-slice computed tomography detects atherosclerosis, whereas MPI detects ischemia; how these 2 techniques compare in patients with an intermediate likelihood of CAD is unknown...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
International journal of cardiology,
Volume 121, Issue 1, 28 4 2006, Pages 123-124
Preoperative determinants of recovery time in adult Fallot patients after late pulmonary valve replacement.
Henkens IR, van Straten A, Hazekamp MG, Schalij MJ, de Roos A, van der Wall EE, Vliegen HW
Abstract
Cited 26 times since 2006 (1.4 per year)
source: EuropePMC
Genes and immunity,
Volume 8, Issue 1, 23 4 2006, Pages 44-50
Interleukin 10: a new risk marker for the development of restenosis after percutaneous coronary intervention.
Monraats PS, Kurreeman FA, Pons D, Sewgobind VD, de Vries FR, Zwinderman AH, de Maat MP, Doevendans PA, de Winter RJ, Tio RA, Waltenberger J, Huizinga TW, Eefting D, Quax PH, Frants RR, van der Laarse A, van der Wall EE, Jukema JW
Genetic factors appear to be important in the process of restenosis after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis. An important mediator in the inflammatory response is interleukin (IL)-10. Our aim was to study whether genetic variants in IL-10 predispose to the risk of restenosis. The GENetic DEterminants of Restenosis (GENDER) study included 3104 patients treated with successful PCI. Target vessel revascularization (TVR) was chosen a...
Abstract
Cited 274 times since 2006 (14.4 per year)
source: EuropePMC
European heart journal,
Volume 28, Issue 1, 22 4 2006, Pages 33-41
Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients.
Ypenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Bax JJ
Aims: At present, 20-30% of patients do not respond to cardiac resynchronization therapy (CRT). In this study, the relation between the extent of viable myocardium and scar tissue vs. response to CRT was evaluated. In addition, the presence of scar tissue in the left ventricular (LV) lead position was specifically related to response to CRT. Methods and results: A total of 51 consecutive patients with ischaemic heart failure and substantial LV dyssynchrony undergoing CRT were included. All patie...
Abstract
Cited 566 times since 2006 (29.8 per year)
source: EuropePMC
Brain : a journal of neurology,
Volume 130, Issue Pt 2, 22 4 2006, Pages 521-534
Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy.
van Vliet EA, da Costa Araújo S, Redeker S, van Schaik R, Aronica E, Gorter JA
Leakage of the blood-brain barrier (BBB) is associated with various neurological disorders, including temporal lobe epilepsy (TLE). However, it is not known whether alterations of the BBB occur during epileptogenesis and whether this can affect progression of epilepsy. We used both human and rat epileptic brain tissue and determined BBB permeability using various tracers and albumin immunocytochemistry. In addition, we studied the possible consequences of BBB opening in the rat for the subsequen...
Abstract
