9543 results
Cited 2 times since 2006 (0.1 per year)
source: EuropePMC
Bio Systems,
Volume 87, Issue 2-3, 10 2 2006, Pages 307-313
Directional hearing in a silicon cricket.
Reeve R, van Schaik A, Jin C, Hamilton T, Torben-Nielsen B, Webb B
Phonotaxis is the ability to orient towards or away from sound sources. Crickets can locate conspecifics by phonotaxis to the calling (mating) song they produce, and can evade bats by negative phonotaxis from echolocation calls. The behaviour and underlying physiology have been studied in some depth, and the auditory system solves this complex problem in a unique manner. Experiments conducted on a simulation model of the system indicated that the mechanism output a directional signal to sounds a...
Abstract
Cited 18 times since 2006 (0.9 per year)
source: EuropePMC
Heart rhythm,
Volume 4, Issue 1, 9 2 2006, Pages 88-91
Incessant ventricular tachycardia in fulminant lymphocytic myocarditis: Evidence for origin in the Purkinje system and successful treatment with ablation.
Zeppenfeld K, Blom NA, Bootsma M, Schalij MJ
Abstract
Cited 29 times since 2006 (1.5 per year)
source: EuropePMC
Molecular and cellular biology,
Volume 26, Issue 20, 5 1 2006, Pages 7731-7746
Identification of new human origins of DNA replication by an origin-trapping assay.
Gerhardt J, Jafar S, Spindler MP, Ott E, Schepers A
Metazoan genomes contain thousands of replication origins, but only a limited number have been characterized so far. We developed a two-step origin-trapping assay in which human chromatin fragments associated with origin recognition complex (ORC) in vivo were first enriched by chromatin immunoprecipitation. In a second step, these fragments were screened for transient replication competence in a plasmid-based assay utilizing the Epstein-Barr virus latent origin oriP. oriP contains two elements,...
Abstract
Cited 17 times since 2006 (0.9 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 5, 1 1 2006, Pages 635-641
Do risk factors influence the diagnostic accuracy of noninvasive coronary angiography with multislice computed tomography?
Schuijf JD, Mollet NR, Cademartiri F, Jukema JW, Lamb HJ, de Roos A, van der Wall EE, de Feyter PJ, Bax JJ
Background: Multislice computed tomography (MSCT) is a relatively new noninvasive imaging modality in the evaluation of patients with suspected coronary artery disease (CAD). Whether diagnostic accuracy is influenced by gender or risk factors for CAD is currently unknown and was evaluated in this study. Methods and results: In 197 patients (171 men and 26 women; mean age, 60 +/- 11 years) 16-slice MSCT was performed and compared with invasive coronary angiography at 2 different centers (Leiden a...
Abstract
Cited 28 times since 2006 (1.5 per year)
source: EuropePMC
The Biochemical journal,
Volume 398, Issue 3, 1 1 2006, Pages 461-467
Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex.
Jayne S, Zwartjes CG, van Schaik FM, Timmers HT
In eukaryotic cells, the Ccr4-Not complex can regulate mRNA metabolism at various levels. Previously, we showed that promoter targeting of the CNOT2 subunit resulted in strong repression of RNA polymerase II transcription, which was sensitive to the HDAC (histone deacetylase) inhibitor, trichostatin A [Zwartjes, Jayne, van den Berg and Timmers (2004) J. Biol. Chem. 279, 10848-10854]. In the present study, the cofactor requirement for CNOT2-mediated repression was investigated. We found that coex...
Abstract
Cited 62 times since 2006 (3.2 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 132, Issue 3, 1 1 2006, Pages 610-620
Surgical ventricular restoration in patients with ischemic dilated cardiomyopathy: evaluation of systolic and diastolic ventricular function, wall stress, dyssynchrony, and mechanical efficiency by pressure-volume loops.
Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Schalij MJ, van der Wall EE, Dion RA
Objectives: Surgical ventricular restoration aims at improving cardiac function by normalization of left ventricular shape and size. Recent studies indicate that surgical ventricular restoration is highly effective with an excellent 5-year outcome in patients with ischemic dilated cardiomyopathy. We used pressure-volume analysis to investigate acute changes in systolic and diastolic left ventricular function, mechanical dyssynchrony and efficiency, and wall stress. Methods: In 3 patient groups (...
Abstract
Cited 7 times since 2006 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 5, 1 1 2006, Pages 629-634
Accuracy of stress Tc-99m tetrofosmin myocardial perfusion tomography for the diagnosis and localization of coronary artery disease in women.
Elhendy A, Schinkel AF, Bax JJ, van Domburg RT, Valkema R, Biagini E, Feringa HH, Poldermans D
Background: Earlier studies have suggested a modest accuracy of stress thallium 201 myocardial perfusion imaging (MPI) for the diagnosis of coronary artery disease (CAD) in women. The accuracy of stress MPI with technetium 99m tetrofosmin has not been studied in women. The aim of this study was to assess the accuracy of stress Tc-99m tetrofosmin MPI for the diagnosis and localization of CAD in women. Methods and results: We studied 88 women who underwent exercise or dobutamine stress Tc-99m tetr...
Abstract
Cited 16 times since 2006 (0.8 per year)
source: EuropePMC
Current opinion in cardiology,
Volume 21, Issue 5, 1 1 2006, Pages 443-449
Prognostic role of dobutamine stress echocardiography in myocardial viability.
Schinkel AF, Poldermans D, Elhendy A, Bax JJ
Purpose of review: The aim of this review is to provide a perspective on the role of dobutamine stress echocardiography to evaluate myocardial viability and assess prognosis in patients with ischemic left ventricular dysfunction. Recent findings: Pooled analysis of currently available data demonstrates that dobutamine stress echocardiography provides useful information on recovery of dysfunctional but viable myocardium and prognosis. In fact, improvement of long-term prognosis may be the ultimat...
Abstract
Cited 2 times since 2006 (0.1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 150, Issue 35, 1 1 2006, Pages 1930-1935
[Favourable results with surgical treatment in 43 children with hypoplastic left-heart syndrome or similar disorders, 1999-2005].
Hazekamp MG, Rijlaarsdam ME, Schoof PH, Wald AA, Blom NA, Ottenkamp J
Objective: To describe the results of surgical treatment of hypoplastic left-heart syndrome (HLHS) and HLHS-like disorders in the Amsterdam-Leiden Centre for Congenital Heart Disease, the Netherlands. Design: Retrospective, descriptive. Method: Data were collected on 43 neonates with HLHS or similar disorders who underwent surgical treatment between December 1999 and December 2005. HLHS was present in 37 patients and 6 had disorders similar to HLHS (unbalanced atrioventricular septal defect, tru...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 14, Issue 9, 1 1 2006, Pages 283-284
Do patients benefit from drug-eluting stents in acute myocardial infarction?
Steens RF, Jukema JW, van der Wall EE
Abstract
Cited 38 times since 2006 (2 per year)
source: EuropePMC
World journal of gastroenterology,
Volume 12, Issue 35, 1 1 2006, Pages 5705-5710
Assessment of oxidative stress in chronic pancreatitis patients.
Verlaan M, Roelofs HM, van-Schaik A, Wanten GJ, Jansen JB, Peters WH, Drenth JP
Aim: To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis (CP) patients in comparison with those in healthy control subjects, by using several different analytical techniques. Methods: Thirty-five CP patients and 35 healthy control subjects were investigated prospectively with respect to plasma levels of thiols, ferric reducing ability of plasma (FRAP, i.e. antioxidant capacity), levels of protein carbonyls and thiobarbituric acid reactive substances...
Abstract
Cited 72 times since 2006 (3.7 per year)
source: EuropePMC
The oncologist,
Volume 11, Issue 8, 1 1 2006, Pages 944-954
Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study.
de Jong FA, Kehrer DF, Mathijssen RH, Creemers GJ, de Bruijn P, van Schaik RH, Planting AS, van der Gaast A, Eskens FA, Janssen JT, Ruit JB, Verweij J, Sparreboom A, de Jonge MJ
Objective: Delayed-type diarrhea is a common side effect of irinotecan and is associated with a bacterial-mediated formation of the active irinotecan metabolite SN-38 from its glucuronide conjugate in the intestine. Based on a pilot study, we hypothesized that concomitant administration of the antibiotic neomycin would diminish exposure of the gut to SN-38 and ameliorate the incidence and severity of diarrhea. Patients and methods: Patients were treated with irinotecan in a multicenter, double-b...
Abstract
Cited 24 times since 2006 (1.2 per year)
source: EuropePMC
Preventive veterinary medicine,
Volume 77, Issue 3-4, 1 1 2006, Pages 186-198
Effect of Neospora caninum-serostatus on culling, reproductive performance and milk production in Dutch dairy herds with and without a history of Neospora caninum-associated abortion epidemics.
Bartels CJ, van Schaik G, Veldhuisen JP, van den Borne BH, Wouda W, Dijkstra T
We quantified the effect of Neospora caninum (NC)-serostatus on culling and (re)production in 83 herds randomly selected from the Dutch dairy herd population (random group) and in 17 herds that had experienced an abortion epidemic associated with NC infection (epidemic-abortion group). In the random group, a single whole-herd blood sampling was done during the spring of 2003, while in the epidemic-abortion group whole-herd blood sampling was done repeatedly at least once a year starting after th...
Abstract
Cited 45 times since 2006 (2.3 per year)
source: EuropePMC
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
Volume 14, Issue 9, 1 1 2006, Pages 777-786
Interpersonal psychotherapy for elderly patients in primary care.
van Schaik A, van Marwijk H, Adèr H, van Dyck R, de Haan M, Penninx B, van der Kooij K, van Hout H, Beekman A
Objective: Interpersonal psychotherapy (IPT) is recommended in most depression treatment guidelines, but little is known about its effectiveness in real-life practice. This study investigates whether IPT, delivered by mental health workers to elderly patients with major depressive disorder, is more effective than usual general practitioners' care (CAU). Methods: A pragmatic randomized, controlled trial was conducted in which 143 patients were allocated to IPT (10 sessions) or to CAU. PRIMar...
Abstract
Cited 144 times since 2006 (7.5 per year)
source: EuropePMC
Stroke,
Volume 37, Issue 10, 31 5 2006, Pages 2531-2534
Transesophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke.
de Bruijn SF, Agema WR, Lammers GJ, van der Wall EE, Wolterbeek R, Holman ER, Bollen EL, Bax JJ
Background and purpose: The merits of transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) in the management of transient ischemic attack (TIA) and stroke patients remains matter of debate. Methods: Two hundred and thirty-one consecutive patients with a recent TIA or stroke for which no definite cause and indication for anticoagulation was assessed after standardized work-up underwent TTE and TEE. Echocardiographic findings were categorized into minor and major risk fa...
Abstract
Cited 191 times since 2006 (9.9 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 26, Issue 11, 31 5 2006, Pages 2552-2559
Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice.
Westerterp M, van der Hoogt CC, de Haan W, Offerman EH, Dallinga-Thie GM, Jukema JW, Havekes LM, Rensen PC
Objective: The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a humanized lipoprotein profile. Methods and results: E3L mice were crossbred with human CETP transgenic mice. On a chow diet, CETP expression increased plasma total cholesterol (TC) (+43%; P
Abstract
Cited 10 times since 2006 (0.5 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 23, Issue 2, 29 5 2006, Pages 159-165
Plasma natriuretic peptide levels reflect changes in heart failure symptoms, left ventricular size and function after surgical mitral valve repair.
Feringa HH, Poldermans D, Klein P, Braun J, Klautz RJ, van Domburg RT, van der Laarse A, van der Wall EE, Dion RA, Bax JJ
Background and aim: N-terminal pro-B-type natriuretic peptide (NT-proBNP) has diagnostic and prognostic value in patients with heart failure. The present prospective study was designed to assess whether changes in NT-proBNP levels after surgical mitral valve repair reflect changes in heart failure symptoms and changes in left atrial size, left ventricular size and left ventricular function. Methods: The study population consisted of 22 patients (mean age: 62.8 +/- 14.2 years, 68% male) undergoin...
Abstract
Cited 24 times since 2006 (1.2 per year)
source: EuropePMC
Journal of neurology,
Volume 253, Issue 12, 28 4 2006, Pages 1572-1580
Comparison of CMT1A and CMT2: similarities and differences.
Bienfait HM, Verhamme C, van Schaik IN, Koelman JH, de Visser BW, de Haan RJ, Baas F, van Engelen BG, de Visser M
To evaluate the clinical and electrophysiological similarities and differences between two large groups of patients with Charcot-Marie-Tooth disease, i.e. CMT1A and CMT2, we performed a post hoc comparison of clinical and electrophysiological data. Most CMT1A and CMT2 patients had the classical CMT phenotype. Age of onset was significantly later in CMT2. Total areflexia was present in approximately half of the CMT1A patients whereas it was rare in CMT2. Foot deformities and weakness of knee exte...
Abstract
Cited 37 times since 2006 (1.9 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 26, Issue 11, 24 4 2006, Pages 2560-2566
Dual PPARalpha/gamma agonist tesaglitazar reduces atherosclerosis in insulin-resistant and hypercholesterolemic ApoE*3Leiden mice.
Zadelaar AS, Boesten LS, Jukema JW, van Vlijmen BJ, Kooistra T, Emeis JJ, Lundholm E, Camejo G, Havekes LM
Objective: We investigated whether the dual PPARalpha/gamma agonist tesaglitazar has anti-atherogenic effects in ApoE*3Leiden mice with reduced insulin sensitivity. Methods and results: ApoE*3Leiden transgenic mice were fed a high-fat (HF) insulin-resistance-inducing diet. One group received a high-cholesterol (HC) supplement (1% wt/wt; HC group). A second group received the same HC supplement along with tesaglitazar (T) 0.5 micromol/kg diet (T group). A third (control) group received a low-chol...
Abstract
Cited 16 times since 2006 (0.8 per year)
source: EuropePMC
Pediatric cardiology,
Volume 27, Issue 5, 23 4 2006, Pages 552-556
Surgical repair of aortopulmonary window: thirty-seven years of experience.
Jansen C, Hruda J, Rammeloo L, Ottenkamp J, Hazekamp MG
An aortopulmonary window (APW) is a communication between the ascending aorta and the pulmonary trunk in the presence of two separate semilunar valves. In order to increase our understanding about the surgical management of this rare lesion and its long-term results, we describe our experience over a 37-year period. Between 1968 and 2005, 18 patients were diagnosed with APW. Seventeen underwent surgical correction. Age at operation ranged from 22 days to 22 years (median, 0.20 years). Follow-up...
Abstract
