Publications
Below you can find a list of our published research.
Op korte termijn komt deze Hart Long Centrum website te vervallen. Alle informatie kunt u vanaf heden vinden op https://www.lumc.nl/patientenzorg/specialistische-centra/hart-long-centrum/voor-patienten/
Below you can find a list of our published research.
6930 results
The Pediatric infectious disease journal, 10 2 2024 Petechial and Purpuric Rashes During a Parvovirus B19 Outbreak: Are Skin Symptoms Differentiated? Kus S, Elvan-Tuz A, Aslan-Saritas U, Yilmaz D
Human parvovirus B19 typically causes erythema infectiosum, but unusual exanthems and hemorrhagic manifestations, such as purpuric-petechial rashes, have also been reported. PVB19-associated purpuric-petechial eruption (PAPPE) should be recognized as a distinct clinical feature of primary parvovirus B19 infection and considered in the differential diagnosis of patients with febrile purpura. This report aims to highlight several scenarios of B19V-associated petechial and purpuric rashes, which ma... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 33, Issue 1, 10 2 2024, Pages 2-4 Career perspectives of early-career cardiologists in the Netherlands. Kalkman DN, Baggen VJM, Beusekamp JC, Kleinnibbelink G, Meijers WC, Peeters FECM, van der Wall SJ, Yilmaz D, Minneboo M, Bosch L
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 38, Issue 3, 9 2 2024, Pages 236-238 Are New Thresholds Required for the Assessment of Right Ventricular Function in Patients With and Without Tricuspid Regurgitation? Galloo X, Ajmone Marsan N
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 7 1 2024, Pages 15266028241301278 Ultrasound-Guided vs Non-Ultrasound-Guided Angio-Seal Vascular Hemosasis After Endovascular Treatment for Peripheral Artery Disease: An Observational Study. Groenewegen FA, Charehbili A, Panfilov IA, Engels C, De Jong WJ, Burgmans M, Van der Bogt KEA, Eefting D, Van der Steenhoven TJ, Van der Linden E, Urlings T
Clinical impact: Ultrasound visualization of vascular closure devices during endovascular access closure leads to a significant decrease in overall and major post interventional access site complications. This non-invasive and often readily available imaging technique could therefore lead to an important decrease in morbidity and subsequent overall health care costs when added to the standard intervention protocol. With the increasing use of endovascular techniques to treat peripheral artery dis... Abstract
The Lancet regional health. Europe, Volume 49, 5 1 2024, Pages 101163 Development and validation of artificial intelligence models for early detection of postoperative infections (PERISCOPE): a multicentre study using electronic health record data. van der Meijden SL, van Boekel AM, Schinkelshoek LJ, van Goor H, Steyerberg EW, Nelissen RGHH, Mesotten D, Geerts BF, de Boer MGJ, Arbous MS, PERISCOPE Group
Background: Postoperative infections significantly impact patient outcomes and costs, exacerbated by late diagnoses, yet early reliable predictors are scarce. Existing artificial intelligence (AI) models for postoperative infection prediction often lack external validation or perform poorly in local settings when validated. We aimed to develop locally valid models as part of the PERISCOPE AI system to enable early detection, safer discharge, and more timely treatment of patients. Methods: We dev... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
European journal of clinical investigation, Volume 55, Issue 3, 5 1 2024, Pages e14368 Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment. Theel WB, de Jong VD, Castro Cabezas M, Grobbee DE, Jukema JW, Trompet S
Background: Liver fibrosis progression is influenced by older age and cardiometabolic risk factors such as obesity and is associated with an increased risk of cardiovascular events. While statins may protect against cardiovascular complications, their effects in elderly individuals with obesity and liver fibrosis are unclear. Method: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) database was used to evaluate the effect of pravastatin on major adverse cardiovascular events... Abstract
Stem cell reports, Volume 20, Issue 1, 5 1 2024, Pages 102371 Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling. Yuan Q, Verbueken D, Dinani R, Kim R, Schoger E, Morsink CD, Simkooei SA, Kemna LJM, Hjortnaes J, Kuster DWD, Boon RA, Zelarayan LC, van der Velden J, Buikema JW
Embryonic signaling pathways exert stage-specific effects during cardiac development, yet the precise signals for proliferation or maturation remain elusive. To uncover the cues for proliferation, we performed a combinatory cell-cycle screen for insulin and glycogen synthase kinase-3 (GSK3) inhibition in spontaneously beating human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Our analysis for proliferation, and subsequential downstream sarcomere development, gene expression... Abstract
BJU international, Volume 135, Issue 5, 4 1 2024, Pages 766-774 The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study. Bosveld J, Nguyen TQ, Boormans JL, Witjes JA, van der Heijden AG, Mehra N, Kiemeney LA, Aben KKH, ProBCI Study Group, Meijer RP, Richters A
Objective: To evaluate whether surgical margin status, alongside existing postoperative risk indicators, improves the identification of bladder cancer patients who may benefit from adjuvant therapy following radical cystectomy (RC). Methods: In this nationwide cohort study, patients aged ≥18 years diagnosed with muscle-invasive bladder cancer (MIBC) without nodal or distant metastasis (cT2-4aN0/xM0) between November 2017 and December 2020 who underwent RC were selected from the Netherlands Cance... Abstract
JTCVS open, Volume 23, 4 1 2024, Pages 69-80 Total aortic arch replacement versus proximal aortic repair for acute type a aortic dissection: A single-center 30-year experience. de Oliveira Marreiros DJ, Arabkhani B, Verhoef JL, Keekstra N, van der Vorst JR, van Schaik J, Braun J, Klautz RJM, Groenwold RHH, Hjortnaes J
Objective: Optimal surgical management of the aortic arch for acute type A aortic dissection remains contentious. We assessed clinical outcomes after total arch replacement and proximal aortic repair (ascending aortic ± hemiarch replacement) for acute type A aortic dissection. Methods: All patients surgically treated for acute type A aortic dissection at our institution between 1992 and 2021 were included. Study end points included all-cause mortality, distal aortic reintervention, stroke, and m... Abstract
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2 1 2024, Pages S1090-3798(24)00172-7 Corrigendum to "Re-examining the characteristics of pediatric multiple sclerosis in the era of antibody-associated demyelinating syndromes" [Europ. J. Paediatr. Neurol. 41 (2022) 8-18 doi.org/10.1016/j.ejpn.2022.08.006]. Yılmaz Ü, Gücüyener K, Yavuz M, Ibrahim Oncel, Canpolat M, Saltık S, Ünver O, Çıtak Kurt AN, Tosun A, Yılmaz S, Özgör B, İlknur Erol, Öztoprak Ü, Elitez DA, Çobanoğulları Direk M, Bodur M, Teber S, Anlar B, Turkish Pediatric Multiple Sclerosis Study Group
European heart journal. Cardiovascular Imaging, Volume 26, Issue 1, 1 1 2024, Pages 173-174 Mural thickening of the coronary arteries in a COVID-19 patient. Groen RA, de Graaf MA, Stöger JL, van der Woude D, Antoni ML
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 26, Issue 12, 1 1 2024, Pages euae283 Ventricular septal defect characteristics influence presence of septal anatomical isthmuses in patients with repaired tetralogy of Fallot. Wallet J, Kimura Y, Blom NA, Hazekamp MG, Bartelings MM, Jongbloed MRM, Zeppenfeld K
Aims: In repaired tetralogy of Fallot (rTOF), the septal anatomical isthmuses (AI), AI 3, between the ventricular septal defect (VSD) and pulmonary annulus, and AI 4, between the VSD and tricuspid annulus, are important ventricular tachycardia (VT) substrates when slow conducting. Our aim was to assess the influence of VSD characteristics, specifically the presence of muscular or fibrous tissue at its border, on the presence or absence of septal AIs, potentially related to VT. Methods and result... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Current protocols, Volume 4, Issue 12, 1 1 2024, Pages e70068 Cryopreservation of Human Adult Ventricular Tissue for the Preparation of Viable Myocardial Slices. Lodrini AM, Groeneveld EJ, Palmen M, Hjortnaes J, Smits AM, Goumans MJ
Living myocardial slices (LMS) are ultrathin sections of adult myocardium that can be maintained in culture. These slices provide a unique platform for studying interactions between cardiomyocytes (CMs), other cardiac cell types, and the extracellular matrix while maintaining the cytoarchitecture and electrical phenotype of CMs over extended periods. Despite their advantages over other cardiac models, LMS have limitations, particularly their reliance on slice quality. The primary factor influenc... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 41, Issue 12, 1 1 2024, Pages e70047 Core Laboratory Versus Center-Reported Echocardiographic Assessment of the Native and Bioprosthetic Aortic Valve. Velders BJJ, Vriesendorp MD, Weissman NJ, Sabik JF, Reardon MJ, Dagenais F, Moront MG, Rao V, Fukuhara S, Günzinger R, van Leeuwen WJ, Brown WM, Groenwold RHH, Klautz RJM, Asch FM
Background: Insights into quantitative differences between core laboratory and center-reported echocardiographic assessment of the native and bioprosthetic aortic valve are lacking. We aimed to explore clinically relevant differences between these evaluations. Methods: Data were used from the PERIcardial SurGical AOrtic Valve ReplacemeNt (PERIGON) Pivotal Trial for the Avalus valve. In this trial, patients with an indication for surgical aortic valve replacement (SAVR) due to aortic stenosis or... Abstract
Journal of travel medicine, Volume 31, Issue 8, 1 1 2024, Pages taae131 Antimicrobial resistance genes acquisition among Dutch intercontinental travellers: a prospective multicentre study. Chan J, van Best N, Arcilla M, van Hattem J, Melles DC, de Jong MD, Schultsz C, van Genderen PJJ, Bootsma MCJ, Goorhuis A, Grobusch MP, Oude Lashof AM, Verbrugh HA, Penders J, COMBAT-Study Consortium
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 67, Issue 1, 1 1 2024, Pages ezae414 Seven-year outcomes after surgical aortic valve replacement with a stented bovine pericardial bioprosthesis in over 1100 patients: a prospective multicentre analysis. Sabik JF, Rao V, Dagenais F, Moront MG, Reardon MJ, Patel HJ, Oh JK, Fukuhara S, Labrousse L, Günzinger R, Baig K, Ito S, Wu T, Klautz RJM, PERIGON Investigators
Objectives: Safety, efficacy and durability are important considerations when selecting a bioprosthesis for aortic valve replacement (AVR). This study assessed 7-year clinical outcomes and haemodynamic performance of the Avalus bioprosthesis. Methods: Patients indicated for surgical AVR were enrolled in this prospective, nonrandomized trial, conducted across 39 sites globally. The primary end-point of this analysis was freedom from surgical explant or percutaneous valve-in-valve reintervention d... Abstract
JACC. Cardiovascular interventions, Volume 17, Issue 23, 1 1 2024, Pages 2713-2731 Tricuspid Valve S-Curves and Chamber Views: Implications for Transcatheter Tricuspid and Pulmonary Valve Interventions, Part 2 of the S-Curves and Chamber Views Series. Zgheib A, De Backer O, Afilalo J, Quagliana A, Campens L, Al Asmar M, Al Ismaili A, Angiolillo D, Ajmone-Marsan N, Von Bardeleben RS, Buithieu J, Cavalcante J, Chetrit M, Choi C, Coisne A, Delgado V, Donal E, Duncan A, Dreyfus J, Fam N, Grapsa J, Granada J, Gackowski A, Hahn R, Ho E, Latib A, Medina de Chazal HA, Martucci G, Maisano F, Messika-Zeitoun D, Modine T, Muraru D, Mousavi N, Praz F, Redwood S, Patterson T, Sarano M, Spaziano M, Swaans M, Sitges M, Zamorano JL, van Mieghem N, Tchetche D, Tournoux F, Wunderlich N, Prendergast B, Piazza N, PCR Tricuspud Valve Focus Group
Despite the challenges associated with periprocedural imaging, transcatheter tricuspid valve interventions have shown important impact on outcomes. A comprehensive understanding of the anatomy of the right heart and surrounding structures is crucial. One way to optimize these interventions is by identifying the optimal fluoroscopic viewing angles along the S-curve of the tricuspid valve. Integration of chamber views using multimodality imaging (multislice computed tomography, fluoroscopy, and ec... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 27, Issue 1, 1 1 2024, Pages euae300 Monitoring and modulating cardiac bioelectricity: from Einthoven to end-user. De Coster T, Nobacht A, Oostendorp T, de Vries AAF, Coronel R, Pijnappels DA
In 2024, we celebrate the 100th anniversary of Willem Einthoven receiving the Nobel Prize for his discovery of the mechanism of the electrocardiogram (ECG). Building on Einthoven's legacy, electrocardiography allows the monitoring of cardiac bioelectricity through solutions to the so-called forward and inverse problems. These solutions link local cardiac electrical signals with the morphology of the ECG, offering a reversible connection between the heart's electrical activity and its r... Abstract
Interdisciplinary cardiovascular and thoracic surgery, Volume 40, Issue 1, 1 1 2024, Pages ivae227 Examining the learning curves in robotic cardiac surgery wet lab simulation training. Atroshchenko GV, Navarra E, Valdis M, Sandoval E, Hashemi N, Cerny S, Pereda D, Palmen M, Bjerrum F, Bruun NH, Tolsgaard MG
Background: Simulation-based training has gained distinction in cardiothoracic surgery as robotic-assisted cardiac procedures evolve. Despite the increasing use of wet lab simulators, the effectiveness of these training methods and skill acquisition rates remain poorly understood. Objectives: This study aimed to compare learning curves and assess the robotic cardiac surgical skill acquisition rate for cardiac and noncardiac surgeons who had no robotic experience in a wet lab simulation setting.... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
The Journal of cardiovascular surgery, Volume 66, Issue 1, 29 5 2024, Pages 3-16 Hemodynamic considerations in arteriovenous vascular access modalities for hemodialysis. White NA, Xiao Z, De Winter EP, Li M, De Vries MR, Van Der Bogt KE, Rotmans JI
Arteriovenous fistulas and arteriovenous grafts are the most commonly used vascular access for hemodialysis in patients with end-stage chronic kidney disease. However, both methods face significant challenges due to the hemodynamic disturbances induced by the arteriovenous anastomosis. This causes changes in vascular structure and blood flow velocity near the anastomosis site after the fistula/graft surgery, and introduces abnormal wall shear stress and cyclic stretch. This leads to endothelial... Abstract