6161 results
Cited 18 times since 2008 (1 per year)
source: EuropePMC
Archives of gerontology and geriatrics,
Volume 48, Issue 1, 4 1 2008, Pages 116-120
Elderly patients undergoing major vascular surgery: risk factors and medication associated with risk reduction.
Feringa HH, Bax JJ, Karagiannis SE, Noordzij P, van Domburg R, Klein J, Poldermans D
This study assesses risk factors in elderly vascular surgery patients and to evaluate whether perioperative cardiac medication can reduce postoperative mortality rate. In a cohort study, 1693 consecutive patients > or =65 years undergoing major non-cardiac vascular surgery were preoperatively screened for cardiac risk factors and medication. During follow-up (median: 8.2 years), mortality was noted. Hospital mortality occurred in 8.1% and long-term mortality in 28.5%. In multivariate analysis...
Abstract
Cited 47 times since 2008 (2.7 per year)
source: EuropePMC
Current pharmaceutical design,
Volume 14, Issue 12, 1 1 2008, Pages 1205-1216
Bridging innate immunity and myocardial ischemia/reperfusion injury: the search for therapeutic targets.
Arslan F, de Kleijn DP, Timmers L, Doevendans PA, Pasterkamp G
Myocardial infarction necessitates new therapeutic interventions, since it still results in high morbidity and mortality worldwide. Reperfusion therapy itself results in (acceleration of) apoptosis, called myocardial ischemia/reperfusion (I/R) injury. For several decades it is known that the inflammatory response during reperfusion is the major cause of myocardial I/R injury. Therapeutic options are limited by lack of (detailed) understanding of intra- and intercellular mechanisms between inflam...
Abstract
Cited 1 times since 2008 (0.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 1, 1 1 2008, Pages 119-128
Imaging highlights from the European Society of Cardiology, American Society of Nuclear Cardiology, and Heart Failure Society of America.
Knuuti J, Poldermans D, Udelson JE, Wackers FJ, Bax JJ
Cardiac imaging has become an integrated part in the diagnostic and prognostic work-up of patients with cardiovascular disease. In this article, highlights of scientific abstracts on cardiac imaging presented at the European Society of Cardiology (ESC), the American Society of Nuclear Cardiology (ASNC), and the Heart Failure Society of America (HFSA) are summarized.
Abstract
Journal of the American College of Cardiology,
Volume 51, Issue 4, 1 1 2008, Pages 490-512
Highlights of the year in JACC 2007.
DeMaria AN, Bax JJ, Ben-Yehuda O, Clopton P, Feld GK, Ginsburg GS, Greenberg BH, Knoke JD, Lew WY, Lima JA, Maisel AS, Narayan SM, Narula J, Sahn DJ, Tsimikas S
Abstract
Cited 26 times since 2008 (1.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 16, Issue 3, 1 1 2008, Pages 79-87
Guidelines for heart transplantation.
de Jonge N, Kirkels JH, Klöpping C, Lahpor JR, Caliskan K, Maat AP, Brügemann J, Erasmus ME, Klautz RJ, Verwey HF, Oomen A, Peels CH, Golüke AE, Nicastia D, Koole MA, Balk AH
Based on the changes in the field of heart transplantation and the treatment and prognosis of patients with heart failure, these updated guidelines were composed by a committee under the supervision of both the Netherlands Society of Cardiology and the Netherlands Association for Cardiothoracic surgery (NVVC and NVT).THE INDICATION FOR HEART TRANSPLANTATION IS DEFINED AS: 'End-stage heart disease not remediable by more conservative measures'.CONTRAINDICATIONS ARE: irreversible pulmonar...
Abstract
Cited 19 times since 2008 (1.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 101, Issue 2, 1 1 2008, Pages 144-148
Comparison of multislice computed tomography to gated single-photon emission computed tomography for imaging of healed myocardial infarcts.
Henneman MM, Schuijf JD, Dibbets-Schneider P, Stokkel MP, van der Geest RJ, van der Wall EE, Bax JJ
The aim of the study was to evaluate the performance of multislice computed tomography (MSCT) for the detection and semiquantitative analysis of healed myocardial infarct in comparison to single-photon emission computed tomography (SPECT). Recently, MSCT was shown to allow detection of myocardial infarct by the presence of hypoenhanced areas. However, direct comparisons to other imaging modalities for infarct imaging were scarce. In 69 patients with healed myocardial infarct (>3 months), the...
Abstract
Cited 178 times since 2008 (10.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 51, Issue 1, 1 1 2008, Pages 37-45
Statins for secondary prevention in elderly patients: a hierarchical bayesian meta-analysis.
Afilalo J, Duque G, Steele R, Jukema JW, de Craen AJ, Eisenberg MJ
Objectives: This study was designed to determine whether statins reduce all-cause mortality in elderly patients with coronary heart disease. Background: Statins continue to be underutilized in elderly patients because evidence has not consistently shown that they reduce mortality. Methods: We searched 5 electronic databases, the Internet, and conference proceedings to identify relevant trials. In addition, we obtained unpublished data for the elderly patient subgroups from 4 trials and for the s...
Abstract
Cited 20 times since 2008 (1.2 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 1, 1 1 2008, Pages 94-106
Noncoronary applications of cardiac multidetector row computed tomography.
Tops LF, Krishnàn SC, Schuijf JD, Schalij MJ, Bax JJ
Multidetector row computed tomography (MDCT) has a high diagnostic accuracy to evaluate coronary artery stenoses. Additionally, the 4-dimensional aspect of cardiac MDCT allows a comprehensive evaluation of cardiac structure and function. Left ventricular volumes and systolic function can be accurately assessed with MDCT, and imaging of myocardial infarction is a promising application of cardiac MDCT. In addition, MDCT may provide anatomical visualization of heart valves. Also, evaluation of anat...
Abstract
Cited 7 times since 2008 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 16, Issue 1, 1 1 2008, Pages 30-32
Epigenetic histone acetylation modifiers in vascular remodelling - new targets for therapy in cardiovascular disease.
Pons D, Jukema JW
Abstract
Cited 2 times since 2008 (0.1 per year)
source: EuropePMC
Multimedia manual of cardiothoracic surgery : MMCTS,
Volume 2008, Issue 915, 1 1 2008, Pages mmcts.2006.002329
Surgery for supravalvular aortic stenosis - the three-patch technique.
Arnáiz E, Koolbergen D, Adsuar A, Hazekamp MG
The objective of this paper is to describe the three-patch technique for repair of supravalvular aortic stenosis (SVAS). Supravalvular aortic stenosis is a rare malformation as a result of an abnormal thickening of the aortic wall. SVAS may present in two forms: a localized form (affecting only the aortic sinotubular junction) and a diffuse form, where the aortic arch and its side branches are also affected. Since 1960, multiple surgical techniques have been described with the aim of relieving t...
Abstract
Cited 3 times since 2008 (0.2 per year)
source: EuropePMC
Mayo Clinic proceedings,
Volume 83, Issue 1, 1 1 2008, Pages 10-12
Can coronary calcification define the warranty period of a normal myocardial perfusion study?
Bax JJ, Schuijf JD
Abstract
Cited 60 times since 2008 (3.5 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 15, Issue 1, 1 1 2008, Pages 127-136
Assessment of left ventricular mechanical dyssynchrony by phase analysis of ECG-gated SPECT myocardial perfusion imaging.
Chen J, Henneman MM, Trimble MA, Bax JJ, Borges-Neto S, Iskandrian AE, Nichols KJ, Garcia EV
Cardiac resynchronization therapy (CRT) has shown benefits in patients with severe heart failure. However, at least 30% of patients selected for CRT by use of traditional criteria (New York Heart Association class III or IV, depressed left ventricular [LV] ejection fraction, and prolonged QRS duration) do not respond to CRT. Recent studies with tissue Doppler imaging have shown that the presence of LV dyssynchrony is an important predictor of response to CRT. Phase analysis has been developed to...
Abstract
Cited 40 times since 2008 (2.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 101, Issue 1, 1 1 2008, Pages 122-126
Influence of renal function on the usefulness of N-terminal pro-B-type natriuretic peptide as a prognostic cardiac risk marker in patients undergoing noncardiac vascular surgery.
Goei D, Schouten O, Boersma E, Welten GM, Dunkelgrun M, Lindemans J, van Gestel YR, Hoeks SE, Bax JJ, Poldermans D
N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) is related to stress-induced myocardial ischemia and/or volume overload, both common in patients with renal dysfunction. This might compromise the prognostic usefulness of NT-pro-BNP in patients with renal impairment before vascular surgery. We assessed the prognostic value of NT-pro-BNP in the entire strata of renal function. In 356 patients (median age 69 years, 77% men), cardiac history, glomerular filtration rate (GFR, ml/min/1.73 m(2)),...
Abstract
Cited 35 times since 2007 (2 per year)
source: EuropePMC
Atherosclerosis,
Volume 200, Issue 1, 27 4 2007, Pages 161-167
High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.
van Acker BA, Botma GJ, Zwinderman AH, Kuivenhoven JA, Dallinga-Thie GM, Sijbrands EJ, Boer JM, Seidell JC, Jukema JW, Kastelein JJ, Jansen H, Verhoeven AJ, REGRESS Study Group
Cholesteryl ester transfer protein (CETP) and hepatic lipase (HL) are two HDL modifying proteins that have both pro- and anti-atherogenic properties. We hypothesized that CETP and HL synergistically affect HDL cholesterol and atherosclerotic risk. To test our hypothesis, we analysed the genotype frequencies of CETP Taq1B (rs708272) and LIPC-514C/T (rs1800588) polymorphisms in male coronary artery disease patients (CAD; n=792) and non-symptomatic controls (n=539). Cases and controls had similar a...
Abstract
Cited 35 times since 2007 (2 per year)
source: EuropePMC
Tuberculosis (Edinburgh, Scotland),
Volume 88, Issue 3, 26 4 2007, Pages 249-261
Double-blind randomized Phase I study comparing rdESAT-6 to tuberculin as skin test reagent in the diagnosis of tuberculosis infection.
Arend SM, Franken WP, Aggerbeck H, Prins C, van Dissel JT, Thierry-Carstensen B, Tingskov PN, Weldingh K, Andersen P
Limited specificity of the tuberculin skin test incited the development of in vitro assays based on Mycobacterium tuberculosis-specific antigens such as ESAT-6 that are lacking in Bacillus Calmette Guérin (BCG). In animal studies, intradermal ESAT-6 was safe and induced specific skin test responses. The aim of the study was to assess the safety of intradermal recombinant dimer ESAT-6 (rdESAT-6) compared with tuberculin and to determine the human dose. The study design was a double-blind Phase I...
Abstract
Cited 82 times since 2007 (4.7 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 19, Issue 4, 20 3 2007, Pages 392-399
Real-time three-dimensional echocardiography permits quantification of left ventricular mechanical dyssynchrony and predicts acute response to cardiac resynchronization therapy.
Marsan NA, Bleeker GB, Ypenburg C, Ghio S, van de Veire NR, Holman ER, van der Wall EE, Tavazzi L, Schalij MJ, Bax JJ
Objective: To evaluate the value of real-time three-dimensional echocardiography (RT3DE) to predict acute response to cardiac resynchronization therapy (CRT). Methods: Sixty consecutive heart failure patients scheduled for CRT were included. RT3DE was performed before and within 48 hours after pacemaker implantation to calculate both left ventricular (LV) volumes and LV dyssynchrony. LV dyssynchrony was defined as the standard deviation of the time taken to reach the minimum systolic volume for...
Abstract
Cited 45 times since 2007 (2.6 per year)
source: EuropePMC
Biochemical and biophysical research communications,
Volume 366, Issue 4, 18 3 2007, Pages 910-916
Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity.
Pols TW, Ottenhoff R, Vos M, Levels JH, Quax PH, Meijers JC, Pannekoek H, Groen AK, de Vries CJ
NR4A nuclear receptors are induced in the liver upon fasting and regulate hepatic gluconeogenesis. Here, we studied the role of nuclear receptor Nur77 (NR4A1) in hepatic lipid metabolism. We generated mice expressing hepatic Nur77 using adenoviral vectors, and demonstrate that these mice exhibit a modulation of the plasma lipid profile and a reduction in hepatic triglyceride. Expression analysis of >25 key genes involved in lipid metabolism revealed that Nur77 inhibits SREBP1c expression. Thi...
Abstract
Cited 2 times since 2007 (0.1 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 35, Issue 3, 18 3 2007, Pages 687
Discrepancy between glucose metabolism and sympathetic nerve terminals in a patient with metastatic paraganglioma.
Rahbar K, Kies P, Stegger L, Juergens KU, Weckesser M
Abstract
Cited 301 times since 2007 (17.4 per year)
source: EuropePMC
European heart journal,
Volume 29, Issue 4, 15 3 2007, Pages 531-556
Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology.
Schroeder S, Achenbach S, Bengel F, Burgstahler C, Cademartiri F, de Feyter P, George R, Kaufmann P, Kopp AF, Knuuti J, Ropers D, Schuijf J, Tops LF, Bax JJ, Working Group Nuclear Cardiology and Cardiac CT, European Society of Cardiology, European Council of Nuclear Cardiology
As a consequence of improved technology, there is growing clinical interest in the use of multi-detector row computed tomography (MDCT) for non-invasive coronary angiography. Indeed, the accuracy of MDCT to detect or exclude coronary artery stenoses has been high in many published studies. This report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT (WG 5) of the European Society of Cardiology and the European Council of Nuclear Cardiology summarizes the present...
Abstract
Cited 23 times since 2007 (1.3 per year)
source: EuropePMC
Journal of applied physiology (Bethesda, Md. : 1985),
Volume 104, Issue 2, 13 2 2007, Pages 446-450
Long-term cardiovascular effects of neonatal dexamethasone treatment: hemodynamic follow-up by left ventricular pressure-volume loops in rats.
Bal MP, de Vries WB, van Oosterhout MF, Baan J, van der Wall EE, van Bel F, Steendijk P
Dexamethasone is clinically applied in preterm infants to treat or prevent chronic lung disease. However, concern has emerged about adverse side effects. The cardiovascular short-term side effects of neonatal dexamethasone treatment are well documented, but long-term consequences are unknown. Previous studies showed suppressed mitosis during dexamethasone treatment, leading to reduced ventricular weight, depressed systolic function, and compensatory dilatation in prepubertal rats. In addition, r...
Abstract
