8216 results
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation,
Volume 47, Issue 2, 26 4 2024, Pages 116-121
Cardiorespiratory fitness in persons with lower limb amputation.
van Schaik L, Blokland IJ, van Kammen K, Houdijk H, Geertzen JHB, Dekker R
The aim of this study is to gain insight in the cardiorespiratory fitness of persons with lower limb amputation (LLA) during rehabilitation, and in potential factors influencing their cardiorespiratory fitness. We performed a retrospective cohort study using data from cardiopulmonary exercise tests. Included participants were adults with LLA. Main outcome was cardiorespiratory fitness expressed as O 2 peak (ml/min/kg) and was directly determined using breath-by-breath gas analysis. O 2 peak was...
Abstract
Cited 3 times since 2024 (2 per year)
source: EuropePMC
Kidney international reports,
Volume 9, Issue 6, 24 4 2024, Pages 1919-1922
Clinical Remission and Reduction of Circulating Nephritic Factors by Combining Rituximab With Belimumab in a Case of Complement Factor 3 Glomerulopathy.
van Schaik M, de Vries APJ, Bemelman FJ, Rabelink TJ, Trouw LA, van Kooten C, Teng YKO
Abstract
Cited 2 times since 2024 (1.4 per year)
source: EuropePMC
Brain & spine,
Volume 4, 23 4 2024, Pages 102776
Discussing sexual health with patients eligible for spine surgery: An online survey in spine surgeon and pain physicians.
Goudman L, van Schaik D, Jager T, Moens M, Scheerlinck T
Introduction: Spinal pain syndromes have a severe impact on the patient's sex life, contributing to a decrease in sexual function and sexual satisfaction. Despite the importance of sexual health on mental and physical wellbeing, sexual health is rarely discussed during consultations. Research question: The aim of this study is to explore to what extent influencing factors can alter the discussion about sexual health during consultations. More specifically, we will evaluate the influence of...
Abstract
Cited 4 times since 2024 (2.7 per year)
source: EuropePMC
Clinical autonomic research : official journal of the Clinical Autonomic Research Society,
Volume 34, Issue 1, 23 4 2024, Pages 45-77
The relevance of the superior cervical ganglion for cardiac autonomic innervation in health and disease: a systematic review.
Chen HS, van Roon L, Ge Y, van Gils JM, Schoones JW, DeRuiter MC, Zeppenfeld K, Jongbloed MRM
Purpose: The heart receives cervical and thoracic sympathetic contributions. Although the stellate ganglion is considered the main contributor to cardiac sympathetic innervation, the superior cervical ganglia (SCG) is used in many experimental studies. The clinical relevance of the SCG to cardiac innervation is controversial. We investigated current morphological and functional evidence as well as controversies on the contribution of the SCG to cardiac innervation. Methods: A systematic literatu...
Abstract
Cited 12 times since 2024 (8.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 110, Issue 6, 23 4 2024, Pages 448-456
Association of right atrial strain and long-term outcome in severe secondary tricuspid regurgitation.
Galloo X, Fortuni F, Meucci MC, Butcher SC, Dietz MF, Prihadi EA, Cosyns B, Delgado V, Bax JJ, Ajmone Marsan N
Objective: Severe secondary tricuspid regurgitation (STR) causes significant right atrial (RA) volume overload, resulting in structural and functional RA-remodelling. This study evaluated whether patients with severe STR and reduced RA function, as assessed by RA-reservoir-strain (RASr), show lower long-term prognosis. Methods: Consecutive patients, from a single centre, with first diagnosis of severe STR and RASr measure available, were included. Extensive echocardiographic analysis comprised m...
Abstract
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
Journal of thoracic disease,
Volume 16, Issue 2, 22 4 2024, Pages 1715-1723
Chest wall resections for sulcus superior tumors.
Ünal S, Heineman DJ, van Dorp M, Winkelman T, Braun J, Dahele M, Dickhoff C
Chemoradiotherapy followed by surgical resection (trimodality therapy) is a guideline recommended treatment for sulcus superior tumors (SST). By definition, SSTs invade the chest wall and therefore require en-bloc chest wall resection with the upper lung lobe or segments. The addition of a chest wall resection, potentially results in higher morbidity and mortality rates when compared to standard anatomical pulmonary resection. This, together with their anatomical location in the thoracic outlet,...
Abstract
Cited 196 times since 2024 (131.5 per year)
source: EuropePMC
Nature,
Volume 627, Issue 8003, 19 3 2024, Pages 347-357
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S, Rayner NW, Bocher O, Arruda AL, Sonehara K, Namba S, Lee SSK, Preuss MH, Petty LE, Schroeder P, Vanderwerff B, Kals M, Bragg F, Lin K, Guo X, Zhang W, Yao J, Kim YJ, Graff M, Takeuchi F, Nano J, Lamri A, Nakatochi M, Moon S, Scott RA, Cook JP, Lee JJ, Pan I, Taliun D, Parra EJ, Chai JF, Bielak LF, Tabara Y, Hai Y, Thorleifsson G, Grarup N, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Kwak SH, Long J, Sun M, Tong L, Chen WM, Nongmaithem SS, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Prins BP, Nicolas A, Yanek LR, Chen G, Brody JA, Kabagambe E, An P, Xiang AH, Choi HS, Cade BE, Tan J, Broadaway KA, Williamson A, Kamali Z, Cui J, Thangam M, Adair LS, Adeyemo A, Aguilar-Salinas CA, Ahluwalia TS, Anand SS, Bertoni A, Bork-Jensen J, Brandslund I, Buchanan TA, Burant CF, Butterworth AS, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 18, Issue 3, 19 3 2024, Pages 274-280
Prediction of the development of new coronary atherosclerotic plaques with radiomics.
Lee SE, Hong Y, Hong J, Jung J, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, Gonçalves PA, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Background: Radiomics is expected to identify imaging features beyond the human eye. We investigated whether radiomics can identify coronary segments that will develop new atherosclerotic plaques on coronary computed tomography angiography (CCTA). Methods: From a prospective multinational registry of patients with serial CCTA studies at ≥ 2-year intervals, segments without identifiable coronary plaque at baseline were selected and radiomic features were extracted. Cox models using clinical risk...
Abstract
Cited 7 times since 2024 (4.7 per year)
source: EuropePMC
European journal of heart failure,
Volume 26, Issue 4, 19 3 2024, Pages 994-1003
Tricuspid regurgitation: Frequency, clinical presentation, management and outcome among patients with severe left-sided valvular heart disease in Europe. Insights from the ESC-EORP Valvular Heart Disease II survey.
Dreyfus J, Komar M, Attias D, De Bonis M, Ruschitzka F, Popescu BA, Laroche C, Tribouilloy C, Bogachev Prokophiev A, Mizariene V, Bax JJ, Maggioni AP, Messika-Zeitoun D, Vahanian A, Iung B, EORP VHD II Registry Investigators Group
Aims: Tricuspid regurgitation (TR) is commonly observed in patients with severe left-sided valvular heart disease (VHD). This study sought to assess TR frequency, management and outcome in this population. Methods and results: Among 6883 patients with severe native left-sided VHD or previous left-sided valvular intervention enrolled in the EURObservational Research Programme prospective VHD II survey, moderate or severe TR was very frequent in patients with severe mitral VHD (30% when mitral ste...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
The American journal of clinical nutrition,
Volume 119, Issue 4, 18 3 2024, Pages 896-907
Two randomized crossover multicenter studies investigating gastrointestinal symptoms after bread consumption in individuals with noncoeliac wheat sensitivity: do wheat species and fermentation type matter?
de Graaf MC, Timmers E, Bonekamp B, van Rooy G, Witteman BJ, Shewry PR, Lovegrove A, America AH, Gilissen LJ, Keszthelyi D, Brouns FJ, Jonkers DMAE
Background: Many individuals reduce their bread intake because they believe wheat causes their gastrointestinal (GI) symptoms. Different wheat species and processing methods may affect these responses. Objectives: We investigated the effects of 6 different bread types (prepared from 3 wheat species and 2 fermentation conditions) on GI symptoms in individuals with self-reported noncoeliac wheat sensitivity (NCWS). Methods: Two parallel, randomized, double-blind, crossover, multicenter studies wer...
Abstract
Cited 4 times since 2024 (2.7 per year)
source: EuropePMC
Ophthalmology science,
Volume 4, Issue 4, 17 3 2024, Pages 100494
Role of Systemic Factors in Improving the Prognosis of Diabetic Retinal Disease and Predicting Response to Diabetic Retinopathy Treatment.
Mellor J, Jeyam A, Beulens JWJ, Bhandari S, Broadhead G, Chew E, Fickweiler W, van der Heijden A, Gordin D, Simó R, Snell-Bergeon J, Tynjälä A, Colhoun H
Topic: To review clinical evidence on systemic factors that might be relevant to update diabetic retinal disease (DRD) staging systems, including prediction of DRD onset, progression, and response to treatment. Clinical relevance: Systemic factors may improve new staging systems for DRD to better assess risk of disease worsening and predict response to therapy. Methods: The Systemic Health Working Group of the Mary Tyler Moore Vision Initiative reviewed systemic factors individually and in multi...
Abstract
Cited 10 times since 2024 (6.7 per year)
source: EuropePMC
European urology open science,
Volume 62, 16 3 2024, Pages 8-15
The Safety, Tolerability, and Preliminary Efficacy of a Gemcitabine-releasing Intravesical System (TAR-200) in American Urological Association-defined Intermediate-risk Non-muscle-invasive Bladder Cancer Patients: A Phase 1b Study.
P van Valenberg FJ, van der Heijden AG, Cutie CJ, Bhanvadia S, Keegan KA, Hampras S, Sweiti H, Maffeo JC, Jin S, Chau A, Reynolds DL, Iarossi C, Kelley A, Li X, Stromberg KA, Michiel Sedelaar JP, Steenbruggen JJO, Somford DM, Alfred Witjes J
Background and objective: Patients with intermediate-risk non-muscle-invasive bladder cancer (IR NMIBC) have a high risk of recurrence and need effective therapies to reduce the risk of disease recurrence or progression. This phase 1b study (NCT02720367) assessed the safety and tolerability of TAR-200, an intravesical drug delivery system, in participants with IR NMIBC. Methods: Participants with recurrent IR NMIBC were eligible. Participants received either two 7-d or two 21-d TAR-200 dosing cy...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
JMIR formative research,
Volume 8, 15 3 2024, Pages e38803
Use Intention and User Expectations of Human-Supported and Self-Help eHealth Interventions: Internet-Based Randomized Controlled Trial.
Cohen Rodrigues TR, Reijnders T, Breeman LD, Janssen VR, Kraaijenhagen RA, Atsma DE, Evers AW
Background: Self-help eHealth interventions provide automated support to change health behaviors without any further human assistance. The main advantage of self-help eHealth interventions is that they have the potential to lower the workload of health care professionals. However, one disadvantage is that they generally have a lower uptake. Possibly, the absence of a relationship with a health care professional (referred to as the working alliance) could lead to negative expectations that hinder...
Abstract
Cited 3 times since 2024 (2 per year)
source: EuropePMC
Therapeutics and clinical risk management,
Volume 20, 14 2 2024, Pages 111-126
Challenges in the Early Diagnosis and Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Adults: Current Perspectives.
van Doorn IN, Eftimov F, Wieske L, van Schaik IN, Verhamme C
Diagnosing Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) poses numerous challenges. The heterogeneous presentations of CIDP variants, its mimics, and the complexity of interpreting electrodiagnostic criteria are just a few of the many reasons for misdiagnoses. Early recognition and treatment are important to reduce the risk of irreversible axonal damage, which may lead to permanent disability. The diagnosis of CIDP is based on a combination of clinical symptoms, nerve conduction study...
Abstract
Cited 3 times since 2024 (2 per year)
source: EuropePMC
The Cochrane database of systematic reviews,
Volume 2, 14 2 2024, Pages CD001797
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy.
Bus SR, de Haan RJ, Vermeulen M, van Schaik IN, Eftimov F
Background: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) causes progressive or relapsing weakness and numbness of the limbs, which lasts for at least two months. Uncontrolled studies have suggested that intravenous immunoglobulin (IVIg) could help to reduce symptoms. This is an update of a review first published in 2002 and last updated in 2013. Objectives: To assess the efficacy and safety of intravenous immunoglobulin in people with chronic inflammatory demyelinating polyra...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
The Journal of physiology,
Volume 602, Issue 5, 13 2 2024, Pages 791-808
Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes.
Scardigli M, Pásek M, Santini L, Palandri C, Conti E, Crocini C, Campione M, Loew LM, de Vries AAF, Pijnappels DA, Pavone FS, Poggesi C, Cerbai E, Coppini R, Kohl P, Ferrantini C, Sacconi L
T-tubules (TT) form a complex network of sarcolemmal membrane invaginations, essential for well-co-ordinated excitation-contraction coupling (ECC) and thus homogeneous mechanical activation of cardiomyocytes. ECC is initiated by rapid depolarization of the sarcolemmal membrane. Whether TT membrane depolarization is active (local generation of action potentials; AP) or passive (following depolarization of the outer cell surface sarcolemma; SS) has not been experimentally validated in cardiomyocyt...
Abstract
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Cardiology and therapy,
Volume 13, Issue 1, 13 2 2024, Pages 69-87
The Clear Value of Coronary Artery Calcification Evaluation on Non-Gated Chest Computed Tomography for Cardiac Risk Stratification.
Groen RA, Jukema JW, van Dijkman PRM, Bax JJ, Lamb HJ, Antoni ML, de Graaf MA
To enhance risk stratification in patients suspected of coronary artery disease, the assessment of coronary artery calcium (CAC) could be incorporated, especially when CAC can be readily assessed on previously performed non-gated chest computed tomography (CT). Guidelines recommend reporting on patients' extent of CAC on these non-cardiac directed exams and various studies have shown the diagnostic and prognostic value. However, this method is still little applied, and no current consensus...
Abstract
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
Japan journal of nursing science : JJNS,
Volume 21, Issue 3, 13 2 2024, Pages e12589
The effect of different bed head angles on the hemodynamic parameters of intensive care patients lying in the supine position: A quasi-experimental study.
Yiğit Avcı Ş, Yılmaz D
Aims: The aim of this study was to research the effect of different bed head angles on the hemodynamic parameters of intensive care patients lying in the supine position. Methods: This study was a non-randomized and non-controlled, quasi-experimental repeated measures study. The study was conducted with 50 intensive care patients aged 18 and over in a general surgery intensive care unit in Turkey. With each patient in the supine position, the bed head was raised to an angle of 0°, 20°, 30°, and...
Abstract
Clinical pharmacology and therapeutics,
Volume 115, Issue 5, 12 2 2024, Pages 1162-1174
Model-Based Prediction of Irinotecan-Induced Grade 4 Neutropenia in Cancer Patients: Influence of Incorporating Germline Genetic Factors in the Model.
Karas S, Mathijssen RHJ, van Schaik RHN, Forrest A, Wiltshire T, Bies RR, Innocenti F
Neutropenia is the major dose-limiting toxicity of irinotecan-based therapy. The objective of this study was to assess whether inclusion of germline genetic variants into a population pharmacokinetic/pharmacodynamic model can improve prediction of irinotecan-induced grade 4 neutropenia and identify novel variants of clinical value. A semimechanistic population pharmacokinetic/pharmacodynamic model was used to predict neutrophil response over time in 197 patients receiving irinotecan. Covariate a...
Abstract
Cited 1 times since 2024 (0.7 per year)
source: EuropePMC
The Pediatric infectious disease journal,
Volume 43, Issue 6, 12 2 2024, Pages e218
A Rare Case Presentation: EBV-related Cold Agglutinin Disease and Venous Thrombosis.
Ağralı Eröz N, Elvan Tüz A, Arslan Maden A, Özcan E, Kara Aksay A, Yılmaz D
Abstract
