Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 5 times since 2007 (0.3 per year) source: EuropePMC
Brain & development, Volume 29, Issue 7, 26 4 2007, Pages 409-412 Cerebrospinal fluid pressures in subacute sclerosing panencephalitis. Olmez A, Yilmaz D, Tan H, Duman O, Güngör S, Okuyaz C, Anlar B
Increased intracranial pressure can rarely be the initial symptom in subacute sclerosing panencephalitis (SSPE). We examined cerebrospinal fluid (CSF) pressures and their correlation with clinical features in 58 patients with SSPE. CSF pressure varied between 50 and 500 mmH2O, mean 210.9+/-103.7 mmH2O. Twenty-five (42%) patients had pressures above 200 mmH2O and 15/58 (25%), above 250 mmH2O. There was no correlation between CSF pressure and neurological disability, spasticity, or clinical stage.... Abstract
Cited 49 times since 2007 (2.6 per year) source: EuropePMC
Diabetes care, Volume 30, Issue 5, 26 4 2007, Pages 1113-1119 Noninvasive assessment of plaque characteristics with multislice computed tomography coronary angiography in symptomatic diabetic patients. Pundziute G, Schuijf JD, Jukema JW, Boersma E, Scholte AJ, Kroft LJ, van der Wall EE, Bax JJ
Objective: Cardiovascular events are high in patients with type 2 diabetes, whereas their risk stratification is more difficult. The higher risk may be related to differences in coronary plaque burden and composition. The purpose of this study was to evaluate whether differences in the extent and composition of coronary plaques in patients with and without diabetes can be observed using multislice computed tomography (MSCT). Research design and methods: MSCT was performed in 215 patients (86 [40... Abstract
Cited 61 times since 2007 (3.3 per year) source: EuropePMC
Circulation, Volume 115, Issue 4, 22 4 2007, Pages 493-500 Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation. Pires NM, Pols TW, de Vries MR, van Tiel CM, Bonta PI, Vos M, Arkenbout EK, Pannekoek H, Jukema JW, Quax PH, de Vries CJ
Background: Restenosis is a common complication after percutaneous coronary interventions and is characterized by excessive proliferation of vascular smooth muscle cells (SMCs). We have shown that the nuclear receptor Nur77 protects against SMC-rich lesion formation, and it has been demonstrated that 6-mercaptopurine (6-MP) enhances Nur77 activity. We hypothesized that 6-MP inhibits neointima formation through activation of Nur77. Methods and results: It is demonstrated that 6-MP increases Nur77... Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 49, Issue 4, 12 2 2007, Pages 502-508 Highlights of the 2006 Scientific sessions of the American Society of Nuclear Cardiology: Montreal, Canada, September 7 to 10, 2006. Bax JJ, Abbott BG, Beanlands RS, Bengel F, Berman DS, Garcia EV, Hendel RC, Mieres JH, Shaw LJ, Wackers FJ
Cited 26 times since 2007 (1.4 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 34, Issue 6, 10 2 2007, Pages 900-909 Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS. Stegger L, Lipke CS, Kies P, Nowak B, Schober O, Buell U, Schäfers M, Schaefer WM
Purpose: The segmentation algorithm ESM based on an elastic surface model was validated for the assessment of left ventricular volumes and ejection fraction from ECG-gated myocardial perfusion SPECT. Additionally, it was compared with the commercially available quantification packages 4D-MSPECT and QGS. Cardiac MRI was used as the reference method. Methods: SPECT and MRI were performed on 70 consecutive patients with suspected or proven coronary artery disease. End-diastolic (EDV) and end-systol... Abstract
Cited 81 times since 2007 (4.3 per year) source: EuropePMC
Circulation, Volume 115, Issue 3, 8 2 2007, Pages 326-332 Cyclooxygenase-2 inhibition increases mortality, enhances left ventricular remodeling, and impairs systolic function after myocardial infarction in the pig. Timmers L, Sluijter JP, Verlaan CW, Steendijk P, Cramer MJ, Emons M, Strijder C, Gründeman PF, Sze SK, Hua L, Piek JJ, Borst C, Pasterkamp G, de Kleijn DP
Background: Cyclooxygenase (COX)-2 expression in the heart increases after myocardial infarction (MI). In murine models of MI, COX-2 inhibition preserves left ventricular dimensions and function. We studied the effect of selective COX-2 inhibition on left ventricular remodeling and function after MI in a pig model. Methods and results: Twenty-two pigs were assigned to COX-2 inhibition with a COX-2 inhibitor (COX-2i; celecoxib 400 mg twice daily; n=14) or a control group (n=8). MI was induced by... Abstract
Cited 5 times since 2007 (0.3 per year) source: EuropePMC
European radiology, Volume 17, Issue 6, 6 1 2007, Pages 1422-1432 Molecular cardiovascular imaging using scintigraphic methods. Stegger L, Schäfers K, Kopka K, Wagner S, Hermann S, Kies P, Law M, Schober O, Schäfers M
Molecular cardiovascular imaging plays an increasingly important role both in basic research and in clinical diagnosis. Scintigraphic methods have long been used to study pathophysiological changes on a cellular and molecular level, and they are likely to remain important molecular imaging modalities in the foreseeable future. This article provides an overview over current developments in cardiovascular molecular imaging using scintigraphic methods. The focus lies on imaging of cardiac innervati... Abstract
Cited 188 times since 2007 (10.1 per year) source: EuropePMC
The American journal of cardiology, Volume 99, Issue 5, 4 1 2007, Pages 657-660 Effect of total scar burden on contrast-enhanced magnetic resonance imaging on response to cardiac resynchronization therapy. Ypenburg C, Roes SD, Bleeker GB, Kaandorp TA, de Roos A, Schalij MJ, van der Wall EE, Bax JJ
It was shown that improvement in left ventricular (LV) function and reverse remodeling after cardiac resynchronization therapy (CRT) were greater in patients with nonischemic cardiomyopathy than in those with ischemic cardiomyopathy. The aim of this study is to evaluate the influence of scar burden on response to CRT. We included 34 patients with ischemic cardiomyopathy (New York Heart Association class 3.1 +/- 0.4, LV ejection fraction 23 +/- 7%). Contrast-enhanced magnetic resonance imaging wa... Abstract
Cited 86 times since 2007 (4.6 per year) source: EuropePMC
The American journal of cardiology, Volume 99, Issue 4, 2 1 2007, Pages 554-557 Intrathoracic impedance monitoring to predict decompensated heart failure. Ypenburg C, Bax JJ, van der Wall EE, Schalij MJ, van Erven L
Intrathoracic impedance measurement has been introduced in the InSync Sentry biventricular implantable cardioverter-defibrillator and may permit the early identification of pulmonary fluid accumulation secondary to left-sided heart failure (HF). An audible alarm (the OptiVol alert) can be triggered when the impedance index increases to greater than a predefined level of 60 Omega . day. The aim of this study was to evaluate the clinical value of the OptiVol alert and its prediction for decompensa... Abstract
Cited 7 times since 2007 (0.4 per year) source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 9, Issue 6, 1 1 2007, Pages 877-882 Tissue cardiovascular magnetic resonance demonstrates regional diastolic dysfunction in remote tissue early after inferior myocardial infarction. Paelinck BP, Vrints CJ, Bax JJ, Bosmans JM, de Roos A, Lamb HJ
Purpose: To investigate regional diastolic and systolic function using tissue cardiovascular magnetic resonance (CMR), early after transmural myocardial infarction of the inferior wall due to single proximal right coronary artery disease. Materials and methods: Velocity encoded CMR was used to measure early diastolic transmitral flow velocity (E), and regional, longitudinal, myocardial systolic (Sa) and early diastolic (Ea) velocities (tissue CMR) in 15 patients with a recent transmural inferior... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
International journal of technology assessment in health care, Volume 23, Issue 4, 1 1 2007, Pages 480-487 Cost-effectiveness of interpersonal psychotherapy for elderly primary care patients with major depression. Bosmans JE, van Schaik DJ, Heymans MW, van Marwijk HW, van Hout HP, de Bruijne MC
Objectives: Major depression is common in elderly patients. Interpersonal psychotherapy (IPT) is a potentially effective treatment for depressed elderly patients. The objective of this study was to evaluate the cost-effectiveness of IPT delivered by mental health workers in primary care practices, for depressed patients 55 years of age and older identified by screening, in comparison with care as usual (CAU). Methods: We conducted a full economic evaluation alongside a randomized controlled tria... Abstract
Cited 37 times since 2007 (2 per year) source: EuropePMC
Dermatology (Basel, Switzerland), Volume 214, Issue 1, 1 1 2007, Pages 15-20 C-kit Asp-816-Val mutation analysis in patients with mastocytosis. Verzijl A, Heide R, Oranje AP, van Schaik RH
Background: Mastocytosis is a heterogeneous group of disorders characterized by abnormal accumulation of mast cells. Objective: Skin biopsies from 24 patients (23 with proven mastocytosis) were screened for the presence of the c-kit Asp-816-Val mutation. Methods: In frozen biopsies, RNA was isolated, cDNA synthesis and PCR, the expected PCR product of 346 bp was obtained from 23 patients. Results: In patients with urticaria pigmentosa, the mutation was detected in 38% of the adults and 25% of th... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 14, Issue 1, 1 1 2007, Pages 75-81 Prognostic value of gated SPECT in patients with left bundle branch block. America YG, Bax JJ, Boersma E, Stokkel M, van der Wall EE
Background: The aim of this study was to assess the prognostic value of quantitative gated technetium 99m tetrofosmin single photon emission computed tomography (SPECT) imaging in patients with left bundle branch block (LBBB). Methods and results: We followed up 101 consecutive patients with LBBB using Tc-99m tetrofosmin gated SPECT imaging. The mean follow-up was 1.24 years (maximum, 2.48 years). Hard endpoints were all-cause death and acute myocardial infarction. Event-free survival curves wer... Abstract
Cited 127 times since 2007 (6.8 per year) source: EuropePMC
European journal of endocrinology, Volume 156, Issue 1, 1 1 2007, Pages 137-142 Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery. Noordzij PG, Boersma E, Schreiner F, Kertai MD, Feringa HH, Dunkelgrun M, Bax JJ, Klein J, Poldermans D
Objective: To determine the relationship between preoperative glucose levels and perioperative mortality in noncardiac, nonvascular surgery. Research design and methods: We performed a case-control study in a cohort of 108 593 patients who underwent noncardiac surgery at the Erasmus MC during 1991-2001. Cases were 989 patients who underwent elective noncardiac, nonvascular surgery and died within 30 days during hospital stay. From the remaining patients, 1879 matched controls (age, sex, calendar... Abstract
Cited 20 times since 2007 (1.1 per year) source: EuropePMC
Anesthesia and analgesia, Volume 104, Issue 1, 1 1 2007, Pages 8-10 Pro: Beta-blockers are indicated for patients at risk for cardiac complications undergoing noncardiac surgery. Schouten O, Bax JJ, Dunkelgrun M, Feringa HH, Poldermans D
Cited 43 times since 2007 (2.3 per year) source: EuropePMC
Epilepsia, Volume 48 Suppl 5, 1 1 2007, Pages 53-64 Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat. Gorter JA, Van Vliet EA, Rauwerda H, Breit T, Stad R, van Schaik L, Vreugdenhil E, Redeker S, Hendriksen E, Aronica E, Lopes da Silva FH, Wadman WJ
We investigated expression of genes involved in the proteolytic process during epileptogenesis in a rat model of temporal lobe epilepsy (TLE). In a previous microarray study we found prominent activation of this process, which reached highest expression during the acute and latent phase (1 week after SE) in CA3 and entorhinal cortex (EC). Detailed analysis shows differences in dynamics of the changes of several protease genes such as cathepsins, caspases, matrix metalloproteinases, and plasminog... Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 9, Issue 1, 1 1 2007, Pages 48-9; author reply 61 Biventricular pacing and transmural dispersion of the repolarization. Swenne CA, van Huysduynen BH, Bax JJ, Bleeker GB, Draisma HH, van Erven L, Molhoek SG, van de Vooren H, van der Wall EE, Schalij MJ
Cited 27 times since 2007 (1.4 per year) source: EuropePMC
Current pharmaceutical design, Volume 13, Issue 10, 1 1 2007, Pages 1039-1052 Chemokines and atherosclerotic plaque progression: towards therapeutic targeting? Kraaijeveld AO, de Jager SC, van Berkel TJ, Biessen EA, Jukema JW
Atherosclerosis is currently viewed as an inflammatory disease in which the initiation and progression of the atherosclerotic plaque towards a rupture prone, unstable plaque is driven by leukocyte recruitment mediated by various inflammatory mediators. Recently, interest in chemotactic cytokines or chemokines with regard to atherosclerosis has been growing as chemokines mediate the influx of leukocytes that is typical of atherothrombosis. The activity of the majority of chemokines is overlapping... Abstract
Cited 6 times since 2007 (0.3 per year) source: EuropePMC
Chemistry (Weinheim an der Bergstrasse, Germany), Volume 13, Issue 34, 1 1 2007, Pages 9561-9571 Intermediates in the destruction of chlorinated C1 hydrocarbons on La-based materials: mechanistic implications. van der Heijden AW, Garcia Ramos M, Weckhuysen BM
Activity experiments using GC analysis of reactor effluent have been combined with in situ IR spectroscopy to elucidate the reaction steps in the destructive adsorption of CHCl3, CH2Cl2, and CH3Cl over LaOCl. The IR results show that during reaction, LaOCl is covered with carbonate, formate, and methoxy groups. The relative amount of each of these surface intermediates depends on the Cl/H ratio of the reactant. The decomposition of the surface species leads to formation of the reaction products,... Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
The American heart hospital journal, Volume 5, Issue 2, 1 1 2007, Pages 110-113 What is the value of QRS duration for the prediction of response to cardiac resynchronization therapy? Bleeker GB, Bax JJ