9618 results
Cited 2 times since 2024 (1.3 per year)
source: EuropePMC
Behavioral ecology and sociobiology,
Volume 78, Issue 1, 15 3 2024, Pages 12
Wild and captive immature orangutans differ in their non-vocal communication with others, but not with their mothers.
Fröhlich M, van Noordwijk MA, Mitra Setia T, van Schaik CP, Knief U
Abstract: In many group-living species, individuals are required to flexibly modify their communicative behaviour in response to current social challenges. To unravel whether sociality and communication systems co-evolve, research efforts have often targeted the links between social organisation and communicative repertoires. However, it is still unclear which social or interactional factors directly predict communicative complexity. To address this issue, we studied wild and zoo-housed immature...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 13, Issue 2, 12 2 2024, Pages e031646
Acute Coronary Syndrome Subphenotypes Based on Repeated Biomarker Measurements in Relation to Long-Term Mortality Risk.
de Bakker M, Scholte NTB, Oemrawsingh RM, Umans VA, Kietselaer B, Schotborgh C, Ronner E, Lenderink T, Aksoy I, van der Harst P, Asselbergs FW, Maas A, Oude Ophuis AJ, Krenning B, de Winter RJ, The SHK, Wardeh AJ, Hermans W, Cramer GE, van Schaik RH, de Rijke YB, Akkerhuis KM, Kardys I, Boersma E, BIOMArCS Investigators †
Background: We aimed to identify patients with subphenotypes of postacute coronary syndrome (ACS) using repeated measurements of high-sensitivity cardiac troponin T, N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and growth differentiation factor 15 in the year after the index admission, and to investigate their association with long-term mortality risk. Methods and results: BIOMArCS (BIOMarker Study to Identify the Acute Risk of a Coronary Syndrome) was an obser...
Abstract
Rural and remote health,
Volume 24, Issue 1, 12 2 2024, Pages 8306
The Murray-Darling Medical Schools Network Research Collaboration: protocol for a longitudinal, multi-university program of work to explore the effect of rurally based medical school programs in the Murray-Darling region.
Turner B, Bullock S, Butler S, Ferrington L, Macartney M, Major L, Monrouxe L, Osuagwu UL, Southwell P, Van Schaik L, Luscombe GM
Introduction: There is now strong evidence to support the positive impact of place-based medical education on the recruitment and retention of the rural health workforce in Australia. Much of this work, however, has been undertaken in the context of 'extended rural clinical placement' - students undertaking part of their medical degree in a rural location. Until recently, there were only a few places in Australia in which students could undertake the entirety of their medical degree in...
Abstract
Cited 18 times since 2024 (11.3 per year)
source: EuropePMC
Nature communications,
Volume 15, Issue 1, 12 2 2024, Pages 494
Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone.
Ba X, Guo Y, Moran RA, Doughty EL, Liu B, Yao L, Li J, He N, Shen S, Li Y, van Schaik W, McNally A, Holmes MA, Zhuo C
Carbapenem-resistant Escherichia coli (CREC) ST410 has recently emerged as a major global health problem. Here, we report a shift in CREC prevalence in Chinese hospitals between 2017 and 2021 with ST410 becoming the most commonly isolated sequence type. Genomic analysis identifies a hypervirulent CREC ST410 clone, B5/H24RxC, which caused two separate outbreaks in a children's hospital. It may have emerged from the previously characterised B4/H24RxC in 2006 and has been isolated in ten other...
Abstract
Cited 5 times since 2024 (3.1 per year)
source: EuropePMC
Frontiers in immunology,
Volume 14, 11 2 2024, Pages 1324618
Establishment and immune phenotyping of patient-derived glioblastoma models in humanized mice.
Liu L, van Schaik TA, Chen KS, Rossignoli F, Borges P, Vrbanac V, Wakimoto H, Shah K
Glioblastoma (GBM) is the most aggressive and common type of malignant brain tumor diagnosed in adults. Preclinical immunocompetent mouse tumor models generated using mouse tumor cells play a pivotal role in testing the therapeutic efficacy of emerging immune-based therapies for GBMs. However, the clinical translatability of such studies is limited as mouse tumor lines do not fully recapitulate GBMs seen in inpatient settings. In this study, we generated three distinct, imageable human-GBM (hGBM...
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
Frontiers in immunology,
Volume 14, 10 2 2024, Pages 1279055
TCRβ clones in muscle tissue share structural features in patients with idiopathic inflammatory myopathy and are associated with disease activity.
Anang DC, Walter HAW, Lim J, Niewold ITG, van der Weele L, Aronica E, Eftimov F, Raaphorst J, van Schaik BDC, van Kampen AHC, van der Kooi AJ, de Vries N
Objectives: To characterize the T cell receptor (TCRβ) repertoire in peripheral blood and muscle tissues of treatment naïve patients with newly diagnosed idiopathic inflammatory myopathies (IIMs). Methods: High throughput RNA sequencing of the TCRβ chain was performed in peripheral blood and muscle tissue in twenty newly-diagnosed treatment-naïve IIM patients (9 DM, 5 NM/OM, 5 IMNM and 1 ASyS) and healthy controls. Results thereof were correlated with markers of disease activity. Results: Muscle...
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 10, Issue 3, 10 2 2024, Pages 502-511
Ventricular Tachycardia Ablation in Patients With Desmoplakin Cardiomyopathy.
Ghannam M, Liang JJ, Hoogendoorn J, Zeppenfeld K, Siontis KC, Asirvatham SJ, Sacher F, Maury P, Gandjbakhch E, Morady F, Bogun F
Background: Desmoplakin (DSP) pathogenic variants are rare causes of arrhythmogenic cardiomyopathy and often involve the right and left ventricles. Ventricular tachycardia (VT) ablations may be required in these patients, but procedural characteristics have not been reported. Objectives: In this study, the authors sought to report a multicenter experience of VT ablation in patients with DSP pathogenic variants. Methods: VT ablations performed in patients with known DSP pathogenic variants were a...
Abstract
Cited 4 times since 2024 (2.5 per year)
source: EuropePMC
JACC. Advances,
Volume 3, Issue 2, 5 1 2024, Pages 100814
Virtual Reality for Pain and Anxiety Management in Cardiac Surgery and Interventional Cardiology.
El Mathari S, Hoekman A, Kharbanda RK, Sadeghi AH, de Lind van Wijngaarden R, Götte M, Klautz RJM, Kluin J
Pain and anxiety are common in patients undergoing cardiac surgery and percutaneous cardiac interventions. Virtual reality (VR) is an emerging non-pharmacological tool for pain and anxiety management. However, its application around cardiac procedures remains relatively unexplored. In this review, we perform a targeted non-systematic literature review to assess the current state-of-the-art of VR for pain and anxiety management in patients undergoing cardiac procedures. Contexts of interest were...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
European urology open science,
Volume 60, 5 1 2024, Pages 15-23
Short-term Changes in Health-related Quality of Life of Patients Undergoing Radical Surgery for Upper Urinary Tract Urothelial Carcinoma: Results from a Prospective Phase 2 Clinical Trial.
van Doeveren T, Remmers S, Atema V, van den Bergh RCN, Boevé ER, Cornel EB, van der Heijden AG, Hendricksen K, Cauberg ECC, Jacobs RAL, Kroon BK, Leliveld AM, Meijer RP, Merks B, Oddens JR, Roelofs L, Somford DM, de Vries P, Wijsman B, Windt WAKM, Zwaan PJ, van Leeuwen PJ, Boormans JL, Aben KKH
Background and objective: The possible negative impact of radical surgery on patients' health-related quality of life (HRQoL) plays an important role in preoperative counseling. Here, we analyzed the HRQoL of patients treated for upper urinary tract urothelial carcinoma (UTUC) in the context of a single-arm phase 2 multicenter study, in which the safety and efficacy of a single preoperative intravesical instillation with mitomycin C were investigated. Our objective was to investigate early...
Abstract
The Thoracic and cardiovascular surgeon,
Volume 73, Issue 1, 5 1 2024, Pages 57-65
Sex Differences in the Histopathology of Acute Type A Aortic Dissections.
Grewal N, Dolmaci OB, Klautz RJ, Poelmann RE
Background: Although sex-related differences in cardiovascular surgery outcomes have increasingly garnered attention in the past decades, knowledge about sex disparities in the pathophysiology of acute type A aortic dissections (ATAADs) remains sparse. In this study, we evaluate the histopathologic and atherosclerotic lesions in female and male ATAAD patients. Methods: A total of 68 patients were studied: 51 ATAAD patients (mean age: 62.5 ± 10.8 years; 49% women) and 17 control patients (mean ag...
Abstract
Journal of experimental child psychology,
Volume 240, 5 1 2024, Pages 105834
Children's expectations about the stability of others' knowledge and preference states.
Kurupınar M, Serbest O, Yılmaz D, Soley G
It is a crucial ability to predict others' psychological states across time and contexts. Focusing on cultural inventions such as songs and stories, we contrasted children's attributions of stability with others' knowledge and preference states across time and space and whether these attributions change as a function of children's familiarity with the known/liked items. Children (91 4-year-olds and 97 6-year-olds) were introduced to characters who knew or liked a song, a stor...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
Computers in biology and medicine,
Volume 169, 3 1 2024, Pages 107949
Fast creation of data-driven low-order predictive cardiac tissue excitation models from recorded activation patterns.
Kabus D, De Coster T, de Vries AAF, Pijnappels DA, Dierckx H
Excitable systems give rise to important phenomena such as heat waves, epidemics and cardiac arrhythmias. Understanding, forecasting and controlling such systems requires reliable mathematical representations. For cardiac tissue, computational models are commonly generated in a reaction-diffusion framework based on detailed measurements of ionic currents in dedicated single-cell experiments. Here, we show that recorded movies at the tissue-level of stochastic pacing in a single variable are suff...
Abstract
Cited 170 times since 2024 (104.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 26, Issue 1, 3 1 2024, Pages 5-17
2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC.
Authors/Task Force Members:, McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Skibelund AK, ESC Scientific Document Group
Document Reviewers: Rudolf A. de Boer (CPG Review Co-ordinator) (Netherlands), P. Christian Schulze (CPG Review Co-ordinator) (Germany), Elena Arbelo (Spain), Jozef Bartunek (Belgium), Johann Bauersachs (Germany), Michael A. Borger (Germany), Sergio Buccheri (Sweden), Elisabetta Cerbai (Italy), Erwan Donal (France), Frank Edelmann (Germany), Gloria Färber (Germany), Bettina Heidecker (Germany), Borja Ibanez (Spain), Stefan James (Sweden), Lars Køber (Denmark), Konstantinos C. Koskinas (Switzerla...
Abstract
Cited 12 times since 2024 (7.4 per year)
source: EuropePMC
NPJ vaccines,
Volume 9, Issue 1, 2 1 2024, Pages 1
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial.
Prins MLM, Roozen GVT, Pothast CR, Huisman W, van Binnendijk R, den Hartog G, Kuiper VP, Prins C, Janse JJ, Lamers OAC, Koopman JPR, Kruithof AC, Kamerling IMC, Dijkland RC, de Kroon AC, Azimi S, Feltkamp MCW, Kuijer M, Jochems SP, Heemskerk MHM, Rosendaal FR, Roestenberg M, Visser LG, Roukens AHE
Fractional dosing can be a cost-effective vaccination strategy to accelerate individual and herd immunity in a pandemic. We assessed the immunogenicity and safety of primary intradermal (ID) vaccination, with a 1/5th dose compared with the standard intramuscular (IM) dose of mRNA-1273 in SARS-CoV-2 naïve persons. We conducted an open-label, non-inferiority, randomized controlled trial in the Netherlands between June and December 2021. One hundred and fifty healthy and SARS-CoV-2 naïve participan...
Abstract
Advances in experimental medicine and biology,
Volume 1441, 1 1 2024, Pages 593-598
Total Anomalous Pulmonary Venous Connections, Human Genetics.
Poelmann RE, Jongbloed MRM, DeRuiter MC
Partial anomalous pulmonary venous connections (PAVC) have been found after abnormal gene expressions involving several syndromes. Total anomalous pulmonary venous connection (TAPVC) is found in conjunction with heterotaxia syndrome as well as several other syndromes. It has been reported with an autosomal dominance with variable expression and incomplete penetrance. The occurrence is also related to environmental factors which may superimpose on a familial susceptibility for TAPVC. Many pathway...
Abstract
Advances in experimental medicine and biology,
Volume 1441, 1 1 2024, Pages 599-614
TAPVR: Molecular Pathways and Animal Models.
Poelmann RE, Jongbloed MRM, DeRuiter MC
The venous pole of the heart where the pulmonary veins will develop encompasses the sinus venosus and the atrium. In the fourth week of development, the sinus venosus consists of a left and a right part receiving blood from the common cardinal vein, the omphalomesenteric and umbilical veins. Asymmetrical expansion of the common atrium corresponds with a rightward shift of the connection of the sinus to the atrium. The right-sided part of the sinus venosus including its tributing cardinal veins e...
Abstract
The Journal of invasive cardiology,
Volume 36, Issue 1, 1 1 2024
Veno-venous extracorporeal membrane oxygenation cannulation in prone position.
Montero-Cabezas JM, Janson JA, Al Amri I, Elzo Kraemer CV
A 54-year-old woman was referred for veno-venous extracorporeal oxygenation membrane (VV-ECMO) due to refractory hypoxic respiratory failure caused by COVID-19, despite mechanical ventilation and prolonged prone positioning.
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
Physical therapy,
Volume 104, Issue 1, 1 1 2024, Pages pzad113
Reliability, Measurement Error, Responsiveness, and Minimal Important Change of the Patient-Specific Functional Scale 2.0 for Patients With Nonspecific Neck Pain.
Thoomes E, Cleland JA, Falla D, Bier J, de Graaf M
Objective: The Patient-Specific Functional Scale (PSFS) is a patient-reported outcome measure used to assess functional limitations. Recently, the PSFS 2.0 was proposed; this instrument includes an inverse numeric rating scale and an additional list of activities that patients can choose. The aim of this study was to assess the test-retest reliability, measurement error, responsiveness, and minimal important change of the PSFS 2.0 when used by patients with nonspecific neck pain. Methods: Patien...
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
Nature medicine,
Volume 30, Issue 1, 1 1 2024, Pages 304
Author Correction: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.
van Dorp J, Pipinikas C, Suelmann BBM, Mehra N, van Dijk N, Marsico G, van Montfoort ML, Hackinger S, Braaf LM, Amarante T, van Steenis C, McLay K, Daletzakis A, van den Broek D, van de Kamp MW, Hendricksen K, de Feijter JM, Boellaard TN, Meijer RP, van der Heijden AG, Rosenfeld N, van Rhijn BWG, Jones G, van der Heijden MS
Abstract
Cited 4 times since 2024 (2.5 per year)
source: EuropePMC
Vascular biology (Bristol, England),
Volume 6, Issue 1, 1 1 2024, Pages e240009
Therapeutic angiogenesis for patients with chronic limb-threatening ischemia: promising or hoax?
Peeters JAHM, Schepers A, Hamming JF, Quax PHA
Chronic limb-threatening ischemia (CLTI) is a critical end-stage disease that leads to high amputation rates. Over the past few decades, therapeutic angiogenesis has attracted a lot of attention as a means to reduce the necessity for amputations. Especially gene- and cell therapy are regarded to as possible treatment modalities to restore the hampered blood flow. So far, early-phase clinical trials often fail to prove a significant clinical improvement in mortality, amputation rate, and ulcer he...
Abstract
