Research

Publications

Below you can find a list of our published research.

9618 results

Cited 12 times since 1999 (0.5 per year) source: EuropePMC

Acta cardiologica, Volume 54, Issue 3, 1 1 1999, Pages 163-168 Treatment and prevention of coronary heart disease by lowering serum cholesterol levels; from the pioneer work of C.D. de Langen to the third "Dutch Consensus on Cholesterol". Jukema JW, Simoons ML

In the beginning of this century a possible relation was observed between cholesterol-rich foods, blood cholesterol levels and atherosclerosis by "pioneers" in this field as Anitschkow and De Langen. In the second half of this century a definite link was established between serum cholesterol levels and development of coronary heart disease (CHD). In angiographic studies it has recently been shown that a decrease in total cholesterol as well as in low-density lipoprotein cholesterol lev... Abstract

International journal of cardiac imaging, Volume 15, Issue 3, 1 1 1999, Pages 209-214 Dynamic obstruction, an unusual complication after aortic valve replacement with a stentless porcine valve. van Roosmalen RP, Baur LH, Braun J, Atsma DE, Hazekamp MG, van der Wall EE, Huysmans HA

In the early nineties, the stentless porcine aortic bioprosthesis has been reintroduced successfully. Because of the limited experience, knowledge of clinical complications is limited. Therefore, we describe an unusual complication of dynamic obstruction after aortic valve replacement with a stentless porcine valve in a 70 year old man 18 months after implantation. We discuss the complications of stentless aortic prostheses known so far, describe operative techniques used and their characteristi... Abstract

Cited 17 times since 1999 (0.6 per year) source: EuropePMC

International journal of cardiac imaging, Volume 15, Issue 3, 1 1 1999, Pages 253-8; discussion 259 Diagnosis and management of anomalous origin of the right coronary artery from the left coronary sinus. Bekedam MA, Vliegen HW, Doornbos J, Jukema JW, de Roos A, van der Wall EE

The anomalous origin of the right coronary artery (RCA) from the left sinus of Valsalva coursing between the aorta and the pulmonary artery or right ventricular outflow tract, is considered a potentially fatal abnormality which may require surgery. However, diagnosing the correct course with coronary arteriography may be difficult. Fast gradient echo magnetic resonance (MR) imaging can be helpful to identify and confirm the course of aberrant coronary arteries and their relationship to the surro... Abstract

Cited 72 times since 1999 (2.7 per year) source: EuropePMC

Journal of food protection, Volume 62, Issue 5, 1 1 1999, Pages 536-539 Acid-adapted Listeria monocytogenes displays enhanced tolerance against the lantibiotics nisin and lacticin 3147. van Schaik W, Gahan CG, Hill C

Log-phase Listeria monocytogenes cells become tolerant to a variety of environmental stresses following acid adaptation at pH 5.5. We demonstrated that adapted cells also exhibit increased tolerance to nisin and, to a lesser extent, lacticin 3147. At nisin concentrations of 100 and 200 IU/ml the survival of acid-adapted cells was approximately 10-fold greater than nonadapted cells. However, acid adaptation had only a moderate effect on the tolerance of L. monocytogenes to lacticin 3147, a phenom... Abstract

Cited 14 times since 1999 (0.5 per year) source: EuropePMC

Journal of dairy science, Volume 82, Issue 5, 1 1 1999, Pages 944-952 Modeling the effect of an outbreak of bovine herpesvirus type 1 on herd-level milk production of Dutch dairy farms. van Schaik G, Shoukri M, Martin SW, Schukken YH, Nielen M, Hage JJ, Dijkhuizen AA

One of the impacts of disease is its effect on milk production. In the present study the effect of an outbreak of bovine herpesvirus type 1 on milk production at the herd level of certified bovine herpesvirus type 1-free dairy farms was modeled. The objective was to study several linear models to quantify the effects of a bovine herpesvirus type 1 outbreak on milk production accounting for the repeated measurements and incorporating our assumptions about the most likely duration of effects of th... Abstract

Cited 48 times since 1999 (1.8 per year) source: EuropePMC

Journal of hepatology, Volume 30, Issue 5, 1 1 1999, Pages 876-881 Hepatic arterial pulsatility index in cirrhosis: correlation with portal pressure. Schneider AW, Kalk JF, Klein CP

Background/aims: Determination of the pulsatility index by means of duplex sonography provides the opportunity to evaluate the vascular resistance of the hepatic artery noninvasively. The aim of this study was to investigate the relationship between the hepatic arterial pulsatility index and the hepatic venous pressure gradient in cirrhosis. Methods: In 50 patients with cirrhosis, hepatic venous pressure gradient was determined in the fasting state. Immediately thereafter, hepatic arterial pulsa... Abstract

Cited 140 times since 1999 (5.3 per year) source: EuropePMC

The Journal of allergy and clinical immunology, Volume 103, Issue 4, 1 1 1999, Pages 630-636 Increased production of IFN-gamma and cysteinyl leukotrienes in virus-induced wheezing. van Schaik SM, Tristram DA, Nagpal IS, Hintz KM, Welliver RC, Welliver RC

Background: An imbalance of production of T-helper lymphocyte cytokines, favoring overproduction of IL-4, is believed to be important in the pathogenesis of allergic asthma. However, less is known about the cytokine response in virus-induced wheezing, which is a major cause of morbidity in asthma. Objective: We undertook this study to determine the magnitude of IFN-gamma, IL-4 and IL-10, and leukotriene (LT) responses in infants and children with virus-induced wheezing. Methods: We measured the... Abstract

Cited 59 times since 1999 (2.2 per year) source: EuropePMC

Journal of lipid research, Volume 40, Issue 4, 1 1 1999, Pages 735-743 Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins. Henderson HE, Kastelein JJ, Zwinderman AH, Gagné E, Jukema JW, Reymer PW, Groenemeyer BE, Lie KI, Bruschke AV, Hayden MR, Jansen H

Lipoprotein lipase (LPL) is crucial in the hydrolysis of triglycerides (TG) in TG-rich lipoproteins in the formation of HDL particles. As both these lipoproteins play an important role in the pathogenesis of atherosclerotic vascular disease, we sought to assess the relationship between post-heparin LPL (PH-LPL) activity and lipids and lipoproteins in a large, well-defined cohort of Dutch males with coronary artery disease (CAD). These subjects were drawn from the REGRESS study, totaled 730 in nu... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 143, Issue 13, 1 1 1999, Pages 702 [Hearing impairment]. van Schaik V

Abstract

Cited 66 times since 1999 (2.5 per year) source: EuropePMC

The American journal of cardiology, Volume 83, Issue 6, 1 1 1999, Pages 852-856 Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis. de Maat MP, Jukema JW, Ye S, Zwinderman AH, Moghaddam PH, Beekman M, Kastelein JJ, van Boven AJ, Bruschke AV, Humphries SE, Kluft C, Henney AM

It has proved difficult to identify high-risk patients for atherosclerosis and to determine how they might respond to medication. Recently, a common promoter variant of the human stromelysin-1 gene has been reported, which has been shown to affect the transcription. We investigated whether this polymorphism had any impact on the risk of events, especially restenosis and progression of coronary artery disease and whether the effect was modulated by treatment with pravastatin. The stromelysin-1 ge... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 143, Issue 13, 1 1 1999, Pages 649-651 [Metabolic acidosis in children: the usefulness of 'anion gap']. Kist-van Holthe tot Echten JE, Maaswinkel-Mooy PD, Berger HM, van der Heijden AJ

Metabolic acidosis occurs frequently in small children. The most common causes are hypoxia, sepsis, gastroenteritis and hypovolaemia. Calculation of the anion gap is useful in establishing the cause. An increased anion gap represents unmeasured anions, e.g. lactate in lactic acidosis. Metabolic acidosis was diagnosed in two boys aged one year and six weeks respectively. The first patient had a normal, the second an increased anion gap in blood. By determining the pH and the anion gap in urine it... Abstract

Cited 3 times since 1999 (0.1 per year) source: EuropePMC

The Journal of the Acoustical Society of America, Volume 105, Issue 2 Pt 1, 1 1 1999, Pages 811-821 Analog very large-scale integrated (VLSI) implementation of a model of amplitude-modulation sensitivity in the auditory brainstem. van Schaik A, Meddis R

An analog very large-scale integrated (VLSI) implementation of a model of signal processing in the auditory brainstem is presented and evaluated. The implementation is based on a model of amplitude-modulation sensitivity in the central nucleus of the inferior colliculus (CNIC) previously described by Hewitt and Meddis [J. Acoust. Soc. Am. 95, 2145-2159 (1994)]. A single chip is used to implement the three processing stages of the model; the inner-hair cell (IHC), cochlear nucleus sustained-chopp... Abstract

Cited 41 times since 1999 (1.5 per year) source: EuropePMC

The American journal of cardiology, Volume 83, Issue 4, 1 1 1999, Pages 558-562 Postsurgical course of patients with congenitally corrected transposition of the great arteries. Voskuil M, Hazekamp MG, Kroft LJ, Lubbers WJ, Ottenkamp J, van der Wall EE, Zwinderman KH, Mulder BJ

Because congenitally corrected transposition is a rare congenital anomaly, little is known about the prognosis of patients with this syndrome. The present study evaluated the functional status and clinical course of 73 patients (42 male and 31 female) aged 10 days to 73 years. Follow-up was 1 week to 37 years (mean 12.7 years). Particular attention was paid to the systemic right ventricle, considering the current controversies about long-term right ventricular function. Survival of patients with... Abstract

Cited 7 times since 1999 (0.3 per year) source: EuropePMC

Basic research in cardiology, Volume 94, Issue 1, 1 1 1999, Pages 23-30 Pretreatment with allopurinol in cardiac hypoxic-ischemic reperfusion injury in newborn lambs exerts its beneficial effect through afterload reduction. Shadid M, Van Bel F, Steendijk P, Dorrepaal CA, Moison R, Van der Velde ET, Baan J

The aim of this study was to determine whether allopurinol (ALLO) reduces reperfusion injury inflicted upon the heart resulting from excess production of free oxygen radicals after hypoxia and ischemia (HI) in newborn animals. We, therefore, produced severe HI in 13 newborn lambs by low O2-ventilation and blood volume reduction. One hour before HI seven lambs received ALLO (20 mg/kg i.v.), six received a placebo (CONT). Cardiac function and hemodynamic parameters were assessed by sequential meas... Abstract

Cited 120 times since 1999 (4.5 per year) source: EuropePMC

Hepatology (Baltimore, Md.), Volume 29, Issue 2, 1 1 1999, Pages 334-339 Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis. Schneider AW, Kalk JF, Klein CP

Administration of angiotensin II causes an increase in portal pressure, and plasma concentration of angiotensin II is elevated in patients with cirrhosis, suggesting that angiotensin II may be involved in the pathogenesis of portal hypertension in cirrhosis. We evaluated the effect of the orally active angiotensin II receptor antagonist, losartan, on portal pressure in patients with cirrhosis and portal hypertension. Thirty patients with severe (hepatic venous pressure gradient [HVPG] >/= 20... Abstract

Cited 109 times since 1999 (4.1 per year) source: EuropePMC

Primates; journal of primatology, Volume 40, Issue 1, 1 1 1999, Pages 105-130 The effects of dominance rank and group size on female lifetime reproductive success in wild long-tailed macaques,Macaca fascicularis. van Noordwijk MA, van Schaik CP

Demographic changes were recorded throughout a 12-year period for three social groups ofMacaca fascicularis in a natural population at Ketambe (Sumatra, Indonesia). We examined the prediction that females' lifetime reproductive success depended on dominance rank and group size. Average birth rate was 0.53 (184 infants born during 349 female years). For mature females (aged 8-20 yr) birth rate reflected physical condition, being higher in years with high food availability and lower in the ye... Abstract

Cited 14 times since 1999 (0.5 per year) source: EuropePMC

Experimental eye research, Volume 68, Issue 1, 1 1 1999, Pages 1-8 Autofluorescence of the diabetic and healthy human cornea in vivo at different excitation wavelengths. Van Schaik HJ, Alkemade C, Swart W, Van Best JA

Corneal autofluorescence is higher in diabetes mellitus patients with retinopathy than in healthy subjects. In this study, the excitation spectra of corneal autofluorescence of diabetic patients and healthy controls in the range 365 nm-480 nm were compared in an attempt to identify the fluorophores responsible for corneal autofluorescence in health and disease (diabetes). Spectral measurements (from one eye) were recorded from five patients with proliferative diabetic retinopathy and five age-ma... Abstract

Cited 92 times since 1999 (3.5 per year) source: EuropePMC

Proceedings of the National Academy of Sciences of the United States of America, Volume 96, Issue 2, 1 1 1999, Pages 778-783 A cytochrome b5 is required for full activity of flavonoid 3', 5'-hydroxylase, a cytochrome P450 involved in the formation of blue flower colors. de Vetten N, ter Horst J, van Schaik HP, de Boer A, Mol J, Koes R

The substitution pattern of anthocyanin pigments is a main determinant of flower color. Flavonoid 3',5'-hydroxylase (F3'5'H) is a cytochrome P450 enzyme (Cyt P450) that catalyzes the 3', 5'-hydroxylation of dihydroflavonols, the precursors of purple anthocyanins. Species such as rose and carnation lack F3'5'H activity and are, therefore, unable to generate purple or blue flowers. Petunia, on the other hand, contains two loci, termed hf1 and hf2, that encod... Abstract

Cited 9 times since 1999 (0.3 per year) source: EuropePMC

European urology, Volume 36, Issue 1, 1 1 1999, Pages 36-39 Effect of an educational multimedia prostate program on the International Prostate Symptom Score. van Schaik P, Ahmed T, Suvakovic N, Hindmarsh JR

Objective: To determine the effect of an interactive multimedia prostate education program (MMP) on self assessment of symptom scores due to benign prostatic hyperplasia (BPH). Methods: The interactive MMP was developed including a computer-administered version of the International Prostate Symptom Score (IPSS) questionnaire. Eighty-eight men referred to the Urology Out-patients with prostatic symptoms entered the study. They first completed the IPSS on paper and secondly used the MMP before com... Abstract

Cited 111 times since 1999 (4.2 per year) source: EuropePMC

Primates; journal of primatology, Volume 40, Issue 1, 1 1 1999, Pages 69-86 The socioecology of fission-fusion sociality in Orangutans. van Schaik CP

Fission-fusion systems can have the group or the individual as their primary unit. In group-based fission-fusion systems, predation risk reduction is the major benefit to grouping, in the individual-based ones the benefits are likely to be primarily social. Orangutans, like chimpanzees, are examples of an individual-based fission-fusion species. The orangutans inhabiting a Sumatran swamp forest (Suaq Balimbing) are more likely than elsewhere to form travel parties. As elsewhere, the main benefit... Abstract