Research

Publications

Below you can find a list of our published research.

9618 results

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 112, Issue 3, 22 4 2021, Pages 1005-1022 Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes. Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ

This International evidence-based nomenclature and classification consensus on the congenital bicuspid aortic valve and its aortopathy recognizes 3 types of bicuspid aortic valve: 1. Fused type, with 3 phenotypes: right-left cusp fusion, right-non cusp fusion and left-non cusp fusion; 2. 2-sinus type with 2 phenotypes: Latero-lateral and antero-posterior; and 3. Partial-fusion or forme fruste. This consensus recognizes 3 bicuspid-aortopathy types: 1. Ascending phenotype; root phenotype; and 3. e... Abstract

Cited 5 times since 2021 (1.2 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 162, Issue 3, 22 4 2021, Pages 781-797 Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional, and research purposes. Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, Khoury GE, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ

Cited 20 times since 2021 (4.9 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 112, Issue 3, 22 4 2021, Pages e203-e235 International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes. Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ

This International Consensus Classification and Nomenclature for the congenital bicuspid aortic valve condition recognizes 3 types of bicuspid valves: 1. The fused type (right-left cusp fusion, right-non-coronary cusp fusion and left-non-coronary cusp fusion phenotypes); 2. The 2-sinus type (latero-lateral and antero-posterior phenotypes); and 3. The partial-fusion (forme fruste) type. The presence of raphe and the symmetry of the fused type phenotypes are critical aspects to describe. The Inter... Abstract

Cited 17 times since 2021 (4.2 per year) source: EuropePMC

The ISME journal, Volume 16, Issue 1, 21 3 2021, Pages 211-220 Evidence for methanobactin "Theft" and novel chalkophore production in methanotrophs: impact on methanotrophic-mediated methylmercury degradation. Kang-Yun CS, Liang X, Dershwitz P, Gu W, Schepers A, Flatley A, Lichtmannegger J, Zischka H, Zhang L, Lu X, Gu B, Ledesma JC, Pelger DJ, DiSpirito AA, Semrau JD

Aerobic methanotrophy is strongly controlled by copper, and methanotrophs are known to use different mechanisms for copper uptake. Some methanotrophs secrete a modified polypeptide-methanobactin-while others utilize a surface-bound protein (MopE) and a secreted form of it (MopE*) for copper collection. As different methanotrophs have different means of sequestering copper, competition for copper significantly impacts methanotrophic activity. Herein, we show that Methylomicrobium album BG8, Methy... Abstract

Cited 1 times since 2021 (0.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 29, Issue 4, 21 3 2021, Pages 2011-2012 Automated artificial intelligence quantification of aortic atherosclerotic calcifications by 18F-sodium fluoride PET/CT. Ng ACT, van Rosendael AR, Bax JJ

Abstract

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

Journal of neuroimmunology, Volume 358, 21 3 2021, Pages 577668 Virus discovery in chronic inflammatory demyelinating polyneuropathy. van Lieverloo GGA, Wieske L, van Schaik IN, Deijs M, van der Hoek L, Eftimov F

The events triggering and/or sustaining the auto-immune response underlying chronic inflammatory demyelinating polyneuropathy (CIDP) are unknown. Similar to Guillain-Barré syndrome (GBS), a viral infection might play a role in CIDP. In this study, an virus detection method (VIDISCA-next generation sequencing) capable of detecting known and unknown viruses, was used to analyze the virome in serum of 47 CIDP patients at different time points of the disease and, when available, in cerebrospinal flu... Abstract

Cited 1 times since 2021 (0.2 per year) source: EuropePMC

The journal of vascular access, Volume 24, Issue 2, 19 3 2021, Pages 277-283 Clinical nurses' knowledge and practices on routine care related to the prevention of complications of peripheral intravenous therapy: A cross-sectional study. Yilmaz DU, Yilmaz D, Karaman D

Aim: The aim of this descriptive and cross-sectional study was to determine the knowledge and practices of nurses related to the prevention of peripheral intravenous therapy (PIT) complications, and to identify the influencing factors. Methods: The study adopted a cross-sectional and descriptive design and was conducted between April and August of 2018 with a total of 214 clinical nurses. The data collection tools employed were a 12-item sociodemographic questionnaire and a 16-item questionnaire... Abstract

Cited 1 times since 2021 (0.2 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 19 3 2021, Pages 689375 Existence and Quality of Data on Control Programs for EU Non-regulated Cattle Diseases: Consequences for Estimation and Comparison of the Probability of Freedom From Infection. Rapaliute E, van Roon A, van Schaik G, Santman-Berends I, Koleci X, Mincu M, Gethmann J, Conrady B, Knific T, Hodnik JJ, Berezowski J, Carmo LP, Madouasse A, Tarpai A, Gerilovych A, Malakauskas A, Sekovska B, Fourichon C, Kalaitzakis E, Roch FF, Houe H, Dudek K, Mõtus K, Ózsvári L, Costa L, Guelbenzu-Gonzalo M, Henry MK, Alishani M, Pozzato N, Hopp P, Juste R, Strain S, Mandelik R, Vilček Š, Autio T, Tamminen LM, Faverjon C

Some European countries have successfully implemented country-specific control programs (CPs) for infectious cattle diseases that are not regulated or are regulated only to a limited extent at the European Union (EU) level. Examples of such diseases include bovine viral diarrhea (BVD), infectious bovine rhinotracheitis (IBR), and Johne's disease (JD). The CPs vary between countries in the design and quality of collected data as well as methods used to detect infection and estimate prevalenc... Abstract

Cited 5 times since 2021 (1.2 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 14, Issue 8, 19 3 2021, Pages e009777 Anatomical Characteristics of the Left Atrium and Left Atrial Appendage in Relation to the Risk of Stroke in Patients With Versus Without Atrial Fibrillation. Smit JM, Simon J, El Mahdiui M, Szaraz L, van Rosendael PJ, Kolassváry M, Szilveszter B, Delgado V, Merkely B, Maurovich-Horvat P, Bax JJ

[Figure: see text]. Abstract

Cited 40 times since 2021 (9.8 per year) source: EuropePMC

Progress in retinal and eye research, Volume 87, 17 3 2021, Pages 100994 Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease. Brinks J, van Dijk EHC, Klaassen I, Schlingemann RO, Kielbasa SM, Emri E, Quax PHA, Bergen AA, Meijer OC, Boon CJF

The choroid is a key player in maintaining ocular homeostasis and plays a role in a variety of chorioretinal diseases, many of which are poorly understood. Recent advances in the field of single-cell RNA sequencing have yielded valuable insights into the properties of choroidal endothelial cells (CECs). Here, we review the role of the choroid in various physiological and pathophysiological mechanisms, focusing on the role of CECs. We also discuss new insights regarding the phenotypic properties... Abstract

Cited 3 times since 2021 (0.7 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 8, 16 3 2021, Pages 682785 Predictive Added Value of Selected Plasma Lipids to a Re-estimated Minimal Risk Tool. Bodini A, Michelucci E, Di Giorgi N, Caselli C, Signore G, Neglia D, Smit JM, Scholte AJHA, Mincarone P, Leo CG, Pelosi G, Rocchiccioli S

Background: Lipidomics is emerging for biomarker discovery in cardiovascular disease, and circulating lipids are increasingly incorporated in risk models to predict cardiovascular events. Moreover, specific classes of lipids, such as sphingomyelins, ceramides, and triglycerides, have been related to coronary artery disease (CAD) severity and plaque characteristics. To avoid unnecessary testing, it is important to identify individuals at low CAD risk. The only pretest model available so far to ru... Abstract

Cited 32 times since 2021 (7.8 per year) source: EuropePMC

European journal of human genetics : EJHG, Volume 30, Issue 10, 15 3 2021, Pages 1105-1113 Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone). Matic M, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Houwink EJF, Mulder H, Rongen GAPJM, Weide JV, Wilffert B, Swen JJ, Guchelaar HJ, Deneer VHM, van Schaik RHN

The current Dutch Pharmacogenetics Working Group (DPWG) guideline, describes the gene-drug interaction between CYP2D6 and the opioids codeine, tramadol and oxycodone. CYP2D6 genotype is translated into normal metaboliser (NM), intermediate metaboliser (IM), poor metaboliser (PM) or ultra-rapid metaboliser (UM). Codeine is contraindicated in UM adults if doses >20 mg every 6 h (q6h), in children ≥12 years if doses >10 mg q6h, or with additional risk factors. In PMs, an alternative analgesic... Abstract

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 15 3 2021, Pages 661459 Added Value of Meat Inspection Data for Monitoring of Dairy Cattle Health in the Netherlands. Veldhuis AMB, Smits D, Bouwknegt M, Worm H, van Schaik G

Meat inspection records of one large cattle slaughterhouse were analyzed to evaluate the added value of slaughterhouse data for cattle health surveillance in the Netherlands. Data were available from January 2015 to September 2018, consisting of 467,361 meat inspection records. Analyses included (1) an assessment of the representativeness of the cattle herds in the slaughterhouse data in relation to the cattle herd population in the Netherlands, and (2) multivariable analyses to quantify associa... Abstract

Cited 5 times since 2021 (1.2 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 30, Issue 1, 14 2 2021, Pages 47-57 The challenge of choosing in cardiovascular risk management. Hoogeveen RM, Hanssen NMJ, Brouwer JR, Mosterd A, Tack CJ, Kroon AA, de Borst GJ, Ten Berg J, van Trier T, van Lennep JR, Liem A, Serné E, Visseren FLJ, Cornel JH, Peters RJG, Jukema JW, Stroes ESG, PANORAMA working group

Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. For many years guidelines have listed optimal preventive therapy. More recently, novel therapeutic options have broadened the options for state-of-the-art CV risk management (CVRM). In the majority of patients with CVD, risk lowering can be achieved by utilising standard preventive medication combined with lifestyle modifications. In a minority of patients, add-on therapies should be considered to further reduce... Abstract

Cited 2 times since 2021 (0.5 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 14 2 2021, Pages 671873 An Overview of Current Approaches and Challenges to the Control of Endemic Infectious Cattle Diseases in Albania. Koleci X, Lilo A, Papa S, Margariti K, van Roon A, Santman-Berends I, van Schaik G, Hodnik JJ, Strain S, Guelbenzu-Gonzalo M, Karalliu E

Agriculture is an important production sector in Albania that makes a significant contribution to the gross domestic product (GDP) and employment. The livestock sector contributes more than half of the agricultural GDP. The Albanian cattle population represents 50% of the total livestock units and accounts for 85% of the national milk production, the rest being supplied by small ruminants. Cattle productivity, health and welfare are hindered by infectious diseases, some of which are also transmi... Abstract

Cited 15 times since 2021 (3.7 per year) source: EuropePMC

Microbiology spectrum, Volume 9, Issue 1, 14 2 2021, Pages e0005821 Spread of Carbapenem-Resistant Klebsiella pneumoniae in an Intensive Care Unit: A Whole-Genome Sequence-Based Prospective Observational Study. Wei L, Wu L, Wen H, Feng Y, Zhu S, Liu Y, Tang L, Doughty E, van Schaik W, McNally A, Zong Z

The aim of this study was to determine the contribution of the contamination of the health care environment in the acquisition of carbapenem-resistant Klebsiella pneumoniae (CRKP) in a CRKP-prevalent setting. We performed a 3-month prospective study in a 20-bed medical intensive care unit (ICU) by collecting rectal/oral swabs from patients within 3 days of ICU admission and weekly thereafter. We also comprehensively sampled the beds and rooms of patients and instruments for patient care every we... Abstract

Cited 7 times since 2021 (1.7 per year) source: EuropePMC

EJVES vascular forum, Volume 52, 14 2 2021, Pages 26-29 Ruptured Aneurysm of the Common Iliac Artery Caused by <i>Brucella melitensis</i>: A Case Report. Willems SA, Buntinx M, Gelinck LBS, van Schaik J, Eefting D

Introduction: Brucella is a genus of aerobic Gram negative bacteria that causes the disease brucellosis. It is considered a zoonotic infection transmitted to humans by ingestion of unpasteurised dairy products. Although aortic involvement is rarely seen, it can be a life threatening complication of this disease. This case report describes a ruptured aneurysm of the common iliac artery (CIA) due to secondary infection by Brucella melitensis. Report: A 79 year old man with a known isolated aneurys... Abstract

Cited 10 times since 2021 (2.4 per year) source: EuropePMC

mSystems, Volume 6, Issue 4, 13 2 2021, Pages e0013721 Metagenome-Wide Analysis of Rural and Urban Surface Waters and Sediments in Bangladesh Identifies Human Waste as a Driver of Antibiotic Resistance. McInnes RS, Uz-Zaman MH, Alam IT, Ho SFS, Moran RA, Clemens JD, Islam MS, van Schaik W

In many low- and middle-income countries, antibiotic-resistant bacteria spread in the environment due to inadequate treatment of wastewater and the poorly regulated use of antibiotics in agri- and aquaculture. Here, we characterized the abundance and diversity of antibiotic-resistant bacteria and antibiotic resistance genes in surface waters and sediments in Bangladesh through quantitative culture of extended-spectrum beta-lactamase (ESBL)-producing coliforms and shotgun metagenomics. Samples we... Abstract

Cited 30 times since 2021 (7.3 per year) source: EuropePMC

BMJ open, Volume 11, Issue 7, 12 2 2021, Pages e050519 Effectiveness of contact tracing apps for SARS-CoV-2: a rapid systematic review. Jenniskens K, Bootsma MCJ, Damen JAAG, Oerbekke MS, Vernooij RWM, Spijker R, Moons KGM, Kretzschmar MEE, Hooft L

Objective: To systematically review evidence on effectiveness of contact tracing apps (CTAs) for SARS-CoV-2 on epidemiological and clinical outcomes. Design: Rapid systematic review. Data sources: EMBASE (OVID), MEDLINE (PubMed), BioRxiv and MedRxiv were searched up to 28 October 2020. Study selection: Studies, both empirical and model-based, assessing effect of CTAs for SARS-CoV-2 on reproduction number (R), total number of infections, hospitalisation rate, mortality rate, and other epidemiolog... Abstract

Cited 31 times since 2021 (7.6 per year) source: EuropePMC

Nature reviews. Cardiology, Volume 18, Issue 12, 12 2 2021, Pages 824-837 Effects of fatty acids on T cell function: role in atherosclerosis. Reilly NA, Lutgens E, Kuiper J, Heijmans BT, Jukema JW

T cells are among the most common cell types present in atherosclerotic plaques and are increasingly being recognized as a central mediator in atherosclerosis development and progression. At the same time, triglycerides and fatty acids have re-emerged as crucial risk factors for atherosclerosis. Triglycerides and fatty acids are important components of the milieu to which the T cell is exposed from the circulation to the plaque, and increasing evidence shows that fatty acids influence T cell fun... Abstract