Research

Publications

Below you can find a list of our published research.

9618 results

Cited 15 times since 2021 (3.3 per year) source: EuropePMC

Evolutionary applications, Volume 14, Issue 4, 29 5 2021, Pages 1124-1144 The ghosts of propagation past: haplotype information clarifies the relative influence of stocking history and phylogeographic processes on contemporary population structure of walleye (Sander vitreus). Bootsma ML, Miller L, Sass GG, Euclide PT, Larson WA

Stocking of fish is an important tool for maintaining fisheries but can also significantly alter population genetic structure and erode the portfolio of within-species diversity that is important for promoting resilience and adaptability. Walleye (Sander vitreus) are a highly valued sportfish in the midwestern United States, a region characterized by postglacial recolonization from multiple lineages and an extensive history of stocking. We leveraged genomic data and recently developed analytical... Abstract

Cited 14 times since 2021 (3.1 per year) source: EuropePMC

Journal of medical microbiology, Volume 70, Issue 3, 28 4 2021 Emergence of carbapenem-resistant Klebsiella pneumoniae harbouring bla OXA-48-like genes in China. Chen Y, Fang L, Yang Y, Yan R, Fu Y, Shen P, Zhao D, Chen Y, Hua X, Jiang Y, Moran RA, van Schaik W, Yu Y

Klebsiella pneumoniae strains carrying OXA-48-like carbapenemases are increasingly prevalent across the globe. There is thus an urgent need to better understand the mechanisms that underpin the dissemination of bla OXA-48-like carbapenemases. To this end, four ertapenem-resistant K. pneumoniae isolates producing OXA-48-like carbapenemases were isolated from two patients. Genome sequencing revealed that one sequence type (ST) 17 isolate carried bla OXA-181, whilst three isolates from a single pat... Abstract

Cited 33 times since 2021 (7.2 per year) source: Scopus

EClinicalMedicine, Volume 32, 28 4 2021, Pages 100731 Short-term outpatient follow-up of COVID-19 patients: A multidisciplinary approach. de Graaf MA, Antoni ML, Ter Kuile MM, Arbous MS, Duinisveld AJF, Feltkamp MCW, Groeneveld GH, Hinnen SCH, Janssen VR, Lijfering WM, Omara S, Postmus PE, Ramai SRS, Rius-Ottenheim N, Schalij MJ, Schiemanck SK, Smid L, Stöger JL, Visser LG, de Vries JJC, Wijngaarden MA, Geelhoed JJM, Roukens AHE

Background: Short-term follow-up of COVID-19 patients reveals pulmonary dysfunction, myocardial damage and severe psychological distress. Little is known of the burden of these sequelae, and there are no clear recommendations for follow-up of COVID-19 patients.In this multi-disciplinary evaluation, cardiopulmonary function and psychological impairment after hospitalization for COVID-19 are mapped. Methods: We evaluated patients at our outpatient clinic 6 weeks after discharge. Cardiopulmonary fu... Abstract

Cited 1 times since 2021 (0.2 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 37, Issue 5, 27 4 2021, Pages 1563-1565 Pacemaker lead-induced tricuspid regurgitation: consider leaflet remodeling. Fortuni F, van der Kley F, Delgado V, Ajmone Marsan N

Abstract

Cited 19 times since 2021 (4.2 per year) source: EuropePMC

Journal of cardiovascular development and disease, Volume 8, Issue 2, 27 4 2021, Pages 12 A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation. Grewal N, Velders BJJ, Gittenberger-de Groot AC, Poelmann R, Klautz RJM, Van Brakel TJ, Lindeman JHN

(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall specimens (n = 58, mean age 63 years) with TAAD were collected. Autopsy tissues (n = 17, mean age 63 years) served as controls. All sections were studied histopathologically. (3) Results: Pathomorphology in TAAD showed predominantly moderate elastic f... Abstract

Cited 5 times since 2021 (1.1 per year) source: EuropePMC

Pediatric pulmonology, Volume 56, Issue 5, 26 4 2021, Pages 1053-1059 Point of care diaphragm ultrasound in acute bronchiolitis: A measurable tool to predict the clinical, sonographic severity of the disease, and outcomes. Şık N, Çitlenbik H, Öztürk A, Yılmaz D, Duman M

Background: The aim of this study was to evaluate diaphragmatic parameters in bronchiolitis patients and identify correlations between clinical and sonographic severity scores and outcomes to develop a more objective and useful tool in the emergency department. Methods: Children aged between 1 and 24 months and diagnosed with acute bronchiolitis were included in the study. The Modified Respiratory Distress Assessment Instrument (mRDAI) score was used to quantify the clinical severity of the dise... Abstract

Cited 31 times since 2021 (6.8 per year) source: EuropePMC

International journal of obesity (2005), Volume 45, Issue 3, 25 4 2021, Pages 687-694 A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients. Kooistra EJ, de Nooijer AH, Claassen WJ, Grondman I, Janssen NAF, Netea MG, van de Veerdonk FL, van der Hoeven JG, Kox M, Pickkers P, RCI-COVID-19 study group

Background/objectives: Obesity appears to be an independent risk factor for ICU admission and a severe disease course in COVID-19 patients. An aberrant inflammatory response and impaired respiratory function have been suggested as underlying mechanisms. We investigated whether obesity is associated with differences in inflammatory, respiratory, and clinical outcome parameters in critically ill COVID-19 patients. Subjects/methods: Sixty-seven COVID-19 ICU patients were divided into obese (BMI ≥ 3... Abstract

Cited 3 times since 2021 (0.7 per year) source: EuropePMC

Cureus, Volume 13, Issue 1, 23 4 2021, Pages e12877 Relationship Between Pituitary Siderosis and Endocrinological Disorders in Pediatric Patients with Beta-Thalassemia. Yılmaz K, Kan A, Çetincakmak MG, Uzel VH, Yılmaz D, Deniz MA, Hattapoglu S

Introduction Excess iron accumulation occurs mainly in organs such as reticuloendothelial cells, the pituitary gland, and the pancreas in beta-thalassemia because of blood transfusions. In the present study, it was aimed to investigate the relationship between T2* values on magnetic resonance imaging (MRI) and clinically diagnosed pituitary endocrinological disorders in children with thalassemia major. Methods This study enrolled patients diagnosed with beta-thalassemia at pediatric hematology o... Abstract

Cited 13 times since 2021 (2.8 per year) source: EuropePMC

Diabetes, obesity & metabolism, Volume 23, Issue 5, 22 4 2021, Pages 1084-1091 Prediction of mortality and major cardiovascular complications in type 2 diabetes: External validation of UK Prospective Diabetes Study outcomes model version 2 in two European observational cohorts. Pagano E, Konings SRA, Di Cuonzo D, Rosato R, Bruno G, van der Heijden AA, Beulens J, Slieker R, Leal J, Feenstra TL

Aim: To externally validate the UK Prospective Diabetes Study Outcomes Model version 2 (UKPDS-OM2) by comparing the predicted and observed outcomes in two European population-based cohorts of people with type 2 diabetes. Materials and methods: We used data from the Casale Monferrato Survey (CMS; n = 1931) and a subgroup of the Hoorn Diabetes Care System (DCS) cohort (n = 5188). The following outcomes were analysed: all-cause mortality, myocardial infarction (MI), ischaemic heart disease (IHD), s... Abstract

Cited 22 times since 2021 (4.8 per year) source: EuropePMC

Appetite, Volume 161, 22 4 2021, Pages 105135 Healthy eating beliefs and the meaning of food in populations with a low socioeconomic position: A scoping review. van der Heijden A, Te Molder H, Jager G, Mulder BC

Profound understanding of healthy eating beliefs in populations with a low socioeconomic position (SEP) can benefit attempts to improve diet quality in this population, but literature on this subject is fragmented. The purpose of this scoping review was to systematically map healthy eating beliefs and the meaning of food and eating in populations with a low SEP. Systematic search of electronic databases yielded 35 relevant publications that were included in a qualitative synthesis. Populations w... Abstract

Cited 148 times since 2021 (32.3 per year) source: EuropePMC

Lancet (London, England), Volume 397, Issue 10272, 21 3 2021, Pages 387-397 Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries. GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery

Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for... Abstract

Cited 1 times since 2021 (0.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 29, Issue 4, 20 3 2021, Pages 1534-1536 Diastolic dyssynchrony by SPECT: A novel parameter to predict post-infarct adverse remodeling. van der Bijl P, Delgado V, Bax JJ

Abstract

Cited 11 times since 2021 (2.4 per year) source: EuropePMC

Cancers, Volume 13, Issue 3, 20 3 2021, Pages 377 Long-Term Experience with Radiofrequency-Induced Hyperthermia Combined with Intravesical Chemotherapy for Non-Muscle Invasive Bladder Cancer. Brummelhuis ISG, Wimper Y, Witjes-van Os HGJM, Arends TJH, van der Heijden AG, Witjes JA

Background: The recurrence rate of non-muscle invasive bladder cancer (NMIBC) is high, despite intravesical treatments. Importantly, patients are frequently unfit or unwilling to undergo a recommended radical cystectomy when standard intravesical treatments fail, due to the substantial risk of morbidity and mortality. For these patients, radiofrequency-induced hyperthermia combined with intravesical chemotherapy (RF-CHT) has shown promising results. We aim to determine treatment outcomes and ass... Abstract

Cited 29 times since 2021 (6.3 per year) source: EuropePMC

Gastroenterology, Volume 160, Issue 6, 19 3 2021, Pages 1970-1985 Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients. Brand EC, Klaassen MAY, Gacesa R, Vich Vila A, Ghosh H, de Zoete MR, Boomsma DI, Hoentjen F, Horjus Talabur Horje CS, van de Meeberg PC, Willemsen G, Fu J, Wijmenga C, van Wijk F, Zhernakova A, Oldenburg B, Weersma RK, Dutch TWIN-IBD consortium and the Dutch Initiative on Crohn and Colitis

Background & aims: It is currently unclear whether reported changes in the gut microbiome are cause or consequence of inflammatory bowel disease (IBD). Therefore, we studied the gut microbiome of IBD-discordant and -concordant twin pairs, which offers the unique opportunity to assess individuals at increased risk of developing IBD, namely healthy cotwins from IBD-discordant twin pairs. Methods: Fecal samples were obtained from 99 twins (belonging to 51 twin pairs), 495 healthy age-, sex-, an... Abstract

Cited 24 times since 2021 (5.2 per year) source: EuropePMC

Circulation, Volume 143, Issue 3, 19 3 2021, Pages 209-211 Changing the Paradigm in the Management of Valvular Heart Disease: In Addition to Left Ventricular Ejection Fraction, Focus on the Myocardium. Fortuni F, Bax JJ, Delgado V

Abstract

Cited 17 times since 2021 (3.7 per year) source: EuropePMC

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Volume 32, Issue 4, 18 3 2021, Pages 720-726 Safety and effectiveness of omalizumab for the treatment of chronic urticaria in pediatric patients. Dekkers C, Alizadeh Aghdam M, de Graaf M, Knulst AC, Meijer Y, van den Reek JMPA, Stadermann MB, Röckmann H

Background: Evidence on safety and effectiveness of omalizumab for treatment of chronic urticaria in pediatric patients is scarce and limited to case reports. In particular, drug survival of omalizumab has not yet been investigated, which is a key element in the evaluation of its clinical performance. The aim of this study was to investigate safety, effectiveness, and drug survival rates of omalizumab in a daily practice cohort of pediatric patients with chronic urticaria (CU). Methods: This is... Abstract

Cited 42 times since 2021 (9.2 per year) source: EuropePMC

Atherosclerosis, Volume 319, 18 3 2021, Pages 51-61 New cardiovascular prevention guidelines: How to optimally manage dyslipidaemia and cardiovascular risk in 2021 in patients needing secondary prevention? Atar D, Jukema JW, Molemans B, Taub PR, Goto S, Mach F, CerezoOlmos C, Underberg J, Keech A, Tokgözoğlu L, Bonaca MP

Elevated low-density lipoprotein cholesterol (LDL-C) is a principally modifiable cause of atherosclerotic cardiovascular disease; accordingly, recent European and US multisociety dyslipidaemia guidelines emphasise the importance of lowering LDL-C to reduce cardiovascular risk. This review provides perspectives on established and emerging agents that reduce LDL-C to help providers synthesize the abundance of new evidence related to prevention of cardiovascular disease. We provide hypothetical cas... Abstract

Cited 9 times since 2021 (2 per year) source: EuropePMC

Zoonoses and public health, Volume 68, Issue 3, 17 3 2021, Pages 194-202 Antimicrobial resistance clusters in commensal Escherichia coli from livestock. Hesp A, Ter Braak C, van der Goot J, Veldman K, van Schaik G, Mevius D

To combat antimicrobial resistance (AMR), policymakers need an overview of evolution and trends of AMR in relevant animal reservoirs, and livestock is monitored by susceptibility testing of sentinel organisms such as commensal E. coli. Such monitoring data are often vast and complex and generates a need for outcome indicators that summarize AMR for multiple antimicrobial classes. Model-based clustering is a data-driven approach that can help to objectively summarize AMR in animal reservoirs. In... Abstract

Cited 3 times since 2021 (0.7 per year) source: EuropePMC

Journal of environmental management, Volume 282, 16 3 2021, Pages 111916 Mathematically formulated key performance indicators for design and evaluation of treatment trains for resource recovery from urban wastewater. van Schaik MO, Sucu S, Cappon HJ, Chen WS, Martinson DB, Ouelhadj D, Rijnaarts HHM

While urban wastewater infrastructure is aging and no longer adequate, climate change and sustainability are urging the transition from pollution management to resource recovery. Lacking evidence-based quantitative evaluation of the potential benefits and consequences of resource recovery from wastewater hinders the negotiation amongst stakeholders and slows down the transition. This study proposes mathematical formulations for technical, environmental, economic, and social key performance indic... Abstract

Cited 7 times since 2021 (1.5 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 7, 15 3 2021, Pages 604821 P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells. de Jong A, de Jong RCM, Peters EA, Arens R, Jukema JW, de Vries MR, Quax PHA

Background: Inflammatory stimuli induced by NF-kB drive atherosclerotic lesion formation. The epigenetic P300/CBP associated factor (PCAF) post-transcriptionally acetylates FoxP3, which is required for regulatory T-cell (Treg) differentiation and immune modulation. We hypothesize that PCAF deficiency affects atherosclerosis via regulation of regulatory Tregs. Method: ApoE3*Leiden (n = 13) and ApoE3*LeidenxPCAF-/- (n = 13) were fed a high-fat diet (HFD) containing 1.25% cholesterol. Systemic FoxP... Abstract