6882 results
Cited 11 times since 2021 (3.1 per year)
source: EuropePMC
Thrombosis research,
Volume 206, 17 3 2021, Pages 66-75
Efficacy and safety of a 12-week outpatient pulmonary rehabilitation program in Post-PE Syndrome.
Boon GJAM, Janssen SMJ, Barco S, Bogaard HJ, Ghanima W, Kroft LJM, Meijboom LJ, Ninaber MK, Nossent EJ, Spruit MA, Symersky P, Vliegen HW, Noordegraaf AV, Huisman MV, Siegerink B, Abbink JJ, Klok FA
Background: The Post-Pulmonary Embolism Syndrome (PPES) comprises heterogeneous entities, including chronic thromboembolic disease with/without pulmonary hypertension (CTEPH/CTEPD), and deconditioning. Objectives: To assess underlying physiological determinants of PPES, and efficacy and safety of rehabilitation training in these patients. Methods: 56 consecutive PE patients with persistent dyspnea and/or functional limitations despite ≥3 months of anticoagulation underwent standardized diagnosti...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 8, 16 3 2021, Pages e009808
Lesion Size and Lesion Maturation After Radiofrequency Catheter Ablation for Ventricular Tachycardia in Humans With Nonischemic Cardiomyopathy.
Glashan CA, Stevenson W, Zeppenfeld K
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Cells,
Volume 10, Issue 8, 12 2 2021, Pages 2064
Generation, Characterization, and Application of Inducible Proliferative Adult Human Epicardium-Derived Cells.
Ge Y, Smits AM, Liu J, Zhang J, van Brakel TJ, Goumans MJTH, Jongbloed MRM, de Vries AAF
Rationale: In recent decades, the great potential of human epicardium-derived cells (EPDCs) as an endogenous cell source for cardiac regeneration has been recognized. The limited availability and low proliferation capacity of primary human EPDCs and phenotypic differences between EPDCs obtained from different individuals hampers their reproducible use for experimental studies. Aim: To generate and characterize inducible proliferative adult human EPDCs for use in fundamental and applied research....
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 14, Issue 8, 12 2 2021, Pages e012612
Hemodynamic Consequences of an Undersized Extracardiac Conduit in an Adult Fontan Patient Revealed by 4-Dimensional Flow Magnetic Resonance Imaging.
Rijnberg FM, van Assen HC, Hazekamp MG, Roest AAW, Westenberg JJM
Abstract
Cited 13 times since 2021 (3.6 per year)
source: EuropePMC
American journal of physiology. Lung cellular and molecular physiology,
Volume 321, Issue 4, 11 2 2021, Pages L775-L786
Disease modeling following organoid-based expansion of airway epithelial cells.
Eenjes E, van Riet S, Kroon AA, Slats AM, Khedoe PPSJ, Boerema-de Munck A, Buscop-van Kempen M, Ninaber DK, Reiss IKM, Clevers H, Rottier RJ, Hiemstra PS
Air-liquid interface (ALI) cultures are frequently used in lung research but require substantial cell numbers that cannot readily be obtained from patients. We explored whether organoid expansion [three-dimensional (3D)] can be used to establish ALI cultures from clinical samples with low epithelial cell numbers. Airway epithelial cells were obtained from tracheal aspirates (TA) from preterm newborns and from bronchoalveolar lavage (BAL) or bronchial tissue (BT) from adults. TA and BAL cells wer...
Abstract
Cited 8 times since 2021 (2.2 per year)
source: EuropePMC
European heart journal open,
Volume 1, Issue 2, 9 2 2021, Pages oeab018
Segmental assessment of blood flow efficiency in the total cavopulmonary connection using four-dimensional flow magnetic resonance imaging: vortical flow is associated with increased viscous energy loss rate.
Rijnberg FM, Juffermans JF, Hazekamp MG, Helbing WA, Lamb HJ, Roest AAW, Westenberg JJM, van Assen HC
Aims: To study flow-related energetics in multiple anatomical segments of the total cavopulmonary connection (TCPC) in Fontan patients from four-dimensional (4D) flow magnetic resonance imaging (MRI), and to study the relationship between adverse flow patterns and segment-specific energetics. Methods and results: Twenty-six extracardiac Fontan patients underwent 4D flow MRI of the TCPC. A segmentation of the TCPC was automatically divided into five anatomical segments [conduit, superior vena cav...
Abstract
Cited 10 times since 2021 (2.8 per year)
source: EuropePMC
Placenta,
Volume 112, 8 2 2021, Pages 189-196
Placenta morphology and biomarkers in pregnancies with congenital heart disease - A systematic review.
Snoep MC, Aliasi M, van der Meeren LE, Jongbloed MRM, DeRuiter MC, Haak MC
Impaired placentation is an important contributing factor to intra-uterine growth restriction and pre-eclampsia in fetuses with congenital heart defects (CHD). These pregnancy complications occur more frequently in pregnancies with fetal CHD. One of the most important factors influencing the life of children with CHD is neurodevelopmental delay, which seems to start already in utero. Delayed neurodevelopment in utero may be correlated or even (partly) explained by impaired placentation in CHD ca...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
International journal of cardiology,
Volume 341, 8 2 2021, Pages 31-38
Determinants of exercise limitation in contemporary paediatric Fontan patients with an extra cardiac conduit.
Harteveld LM, Blom NA, Terol Espinosa de Los Monteros C, van Dijk JG, Kuipers IM, Rammeloo LAJ, de Geus EJC, Hazekamp MG, Ten Harkel ADJ
Background: Although various determinants of exercise limitation in Fontan patients have been studied, most research has been performed in patients who underwent different surgical procedures with differing haemodynamic characteristics. The aim of the current study was to evaluate non-invasively measured cardiovascular parameters and their influence on exercise performance in paediatric Fontan patients with an extracardiac conduit and moderate-good systolic ventricular function. Methods: Fontan...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 5, 6 1 2021, Pages 3539-3546
Sex differences in prognosis of significant secondary mitral regurgitation.
Namazi F, van der Bijl P, Vo NM, van Wijngaarden SE, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Secondary mitral regurgitation (MR) is more frequent in men than in women. However, little is known about differences in prognosis between men and women with secondary MR. The objective of this study is to investigate the sex distribution of secondary MR and the prognostic differences between sexes. Methods: Patients with significant secondary MR, of both ischaemic and non-ischaemic aetiologies, were identified through the departmental electronic patient files and retrospectively analysed....
Abstract
Cited 6 times since 2021 (1.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 157, 6 1 2021, Pages 15-21
Changes in Global Left Ventricular Myocardial Work Indices and Stunning Detection 3 Months After ST-Segment Elevation Myocardial Infarction.
Lustosa RP, Fortuni F, van der Bijl P, Mahdiui ME, Montero-Cabezas JM, Kostyukevich MV, Knuuti J, Marsan NA, Delgado V, Bax JJ
Global left ventricular (LV) myocardial work (MW) indices (GLVMWI) are derived from speckle tracking echocardiographic strain data in combination with non-invasive blood pressure measurements. Changes in global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE) after ST-segment elevation myocardial infarction (STEMI) have not been explored. The aim of present study was to assess the evolution of GLVMWI in STEMI patients from baseline (inde...
Abstract
Cited 27 times since 2021 (7.5 per year)
source: EuropePMC
The European respiratory journal,
Volume 58, Issue 2, 5 1 2021, Pages 2100636
Home monitoring reduced short stay admissions in suspected COVID-19 patients: COVID-box project.
Dirikgil E, Roos R, Groeneveld GH, Heringhaus C, Silven AV, Petrus AHJ, Villalobos-Quesada M, Tsonaka R, van der Boog PJM, Rabelink TJ, Bos WJW, Chavannes NH, Atsma DE, Teng YKO
Abstract
JTCVS open,
Volume 8, 5 1 2021, Pages 300
Reply from authors: Many roads lead to Rome.
Wijngaarden AL, Tomšič A, Marsan NA, Palmen M
Abstract
Cited 13 times since 2021 (3.6 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 5 1 2021, Pages 683849
The Influence of Respiration on Blood Flow in the Fontan Circulation: Insights for Imaging-Based Clinical Evaluation of the Total Cavopulmonary Connection.
van der Woude SFS, Rijnberg FM, Hazekamp MG, Jongbloed MRM, Kenjeres S, Lamb HJ, Westenberg JJM, Roest AAW, Wentzel JJ
Congenital heart disease is the most common birth defect and functionally univentricular heart defects represent the most severe end of this spectrum. The Fontan circulation provides an unique solution for single ventricle patients, by connecting both caval veins directly to the pulmonary arteries. As a result, the pulmonary circulation in Fontan palliated patients is characterized by a passive, low-energy circulation that depends on increased systemic venous pressure to drive blood toward the l...
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
Cardiology in the young,
Volume 32, Issue 5, 5 1 2021, Pages 794-799
Acute kidney injury after the arterial switch operation: incidence, risk factors, and outcomes.
Schoenmaker NJ, Weeda JA, van der Palen RLF, Hazekamp MG, Bunker-Wiersma HE
Background: The aim of this retrospective cohort study was to determine the incidence, potential risk factors, characteristics, and outcomes of acute kidney injury in children following the arterial switch operation for transposition of the great arteries. Methods: Retrospective review of children who underwent ASO between 2000 and 2020 in our tertiary children's hospital in the Netherlands. Pre-and post-ASO serum creatinine levels were collected. Severe AKI was defined as 100% serum creati...
Abstract
Cited 63 times since 2021 (17.6 per year)
source: EuropePMC
The Science of the total environment,
Volume 799, 4 1 2021, Pages 149456
Droplet digital RT-PCR to detect SARS-CoV-2 signature mutations of variants of concern in wastewater.
Heijnen L, Elsinga G, de Graaf M, Molenkamp R, Koopmans MPG, Medema G
Wastewater surveillance has shown to be a valuable and efficient tool to obtain information about the trends of COVID-19 in the community. Since the recent emergence of new variants, associated with increased transmissibility and/or antibody escape (variants of concern), there is an urgent need for methods that enable specific and timely detection and quantification of the occurrence of these variants in the community. In this study, we demonstrate the use of RT-ddPCR on wastewater samples for s...
Abstract
Cited 5 times since 2021 (1.4 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 8, Issue 8, 4 1 2021, Pages 93
Applicability of the Leiden Convention and the Lipton Classification in Patients with a Single Coronary Artery in the Setting of Congenital Heart Disease.
Katekaru-Tokeshi DI, Jiménez-Santos M, Koppel CJ, Vliegen HW, Díaz-Zamudio M, Castillo-Castellón F, Jongbloed MRM, Kimura-Hayama E
In single coronary artery (SCA) anatomy, all coronary tributaries arise from a single ostium, providing perfusion to the entire myocardium. Coronary classification systems can facilitate the description of SCA anatomy. Aim: Evaluation of the applicability of Lipton classification and the Leiden Convention coronary coding system in SCA. Methods: All patients (n = 6209) who underwent computed tomography (CT) scanning between 2014 and 2018 were retrospectively examined for the presence of SCA and c...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Omega,
Volume 87, Issue 3, 3 1 2021, Pages 999-1016
A Phenomenological Analysis of Experiences and Practices of Nurses Providing Palliative and End of Life Care.
Uzelli Yilmaz D, Yilmaz D, Duzgun G, Akin E
The aim of this study was to describe the experiences and practices of nurses providing palliative and end of life care. The study was conducted in the palliative care unit of a territory hospital in Turkey. The sample consisted of 11 nurses who had been working as palliative care nurses for at least one year. The face to face interview method was used to collect data, with a semi-structured in-depth individual interview. 5 main themes and 24 sub-themes were emerged in relation to the experience...
Abstract
Cited 5 times since 2021 (1.4 per year)
source: EuropePMC
Obesity (Silver Spring, Md.),
Volume 29, Issue 9, 2 1 2021, Pages 1439-1444
Microvascular differences in individuals with obesity at risk of developing cardiovascular disease.
van der Velden AIM, van den Berg BM, van den Berg BM, de Mutsert R, van der Vlag J, Jukema JW, Rosendaal FR, Rabelink TJ, Vink H
Objective: This study aimed to investigate microvascular differences in individuals with obesity at risk for developing cardiovascular disease. Methods: In this cross-sectional Netherlands Epidemiology of Obesity study, participant sublingual microcirculation was assessed with a newly developed GlycoCheck software (Microvascular Health Solutions Inc., Salt Lake City, Utah), which integrates red blood cell velocity within the smallest capillaries (4-7 µm) and feed vessels (>10 µm). Framingham...
Abstract
Cited 41 times since 2021 (11.4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 78, Issue 5, 1 1 2021, Pages 421-433
Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.
Schwartz GG, Szarek M, Bittner VA, Diaz R, Goodman SG, Jukema JW, Landmesser U, López-Jaramillo P, Manvelian G, Pordy R, Scemama M, Sinnaeve PR, White HD, Gabriel Steg P, ODYSSEY Outcomes Committees and Investigators
Background: Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk. Objectives: In a post hoc analysis of the ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Synd...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 23, Issue 8, 1 1 2021, Pages 1275-1284
Myocardial calcification is associated with endocardial ablation failure of post-myocardial infarction ventricular tachycardia.
de Riva M, Naruse Y, Ebert M, Watanabe M, Scholte AJ, Wijnmaalen AP, Trines SA, Schalij MJ, Montero-Cabezas JM, Zeppenfeld K
Aims: In patients with post-myocardial infarction (post-MI) ventricular tachycardia (VT), the presence of myocardial calcification (MC) may prevent heating of a subepicardial VT substrate contributing to endocardial ablation failure. The aims of this study were to assess the prevalence of MC in patients with post-MI VT and evaluate the impact of MC on outcome after endocardial ablation. Methods and results: In 158 patients, the presence of MC was retrospectively assessed on fluoroscopy recording...
Abstract
