6940 results
Cited 60 times since 2016 (6.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 67, Issue 3, 1 1 2016, Pages 275-287
Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Hjortnaes J, Beaudoin J, Szymanski C, Bartko PE, Seybolt MM, Handschumacher MD, Sullivan S, Garcia ML, Mauskapf A, Titus JS, Wylie-Sears J, Irvin WS, Chaput M, Messas E, Hagège AA, Carpentier A, Levine RA, Leducq Transatlantic Mitral Network
Background: In patients with myocardial infarction (MI), leaflet tethering by displaced papillary muscles induces mitral regurgitation (MR), which doubles mortality. Mitral valves (MVs) are larger in such patients but fibrosis sets in counterproductively. The investigators previously reported that experimental tethering alone increases mitral valve area in association with endothelial-to-mesenchymal transition. Objectives: The aim of this study was to explore the clinically relevant situation of...
Abstract
Nederlands tijdschrift voor geneeskunde,
Volume 160, 1 1 2016, Pages A9290
[Preference for endovascular aortic aneurysm repair: results of RCTs versus nationwide audits].
Geelkerken RH, Hamming JF
This short comment puts into perspective the value of randomised controlled clinical trials in comparison with nationwide audits in the field of aortic aneurysm treatment. RCTs represent greater scientific value but nationwide audits represent daily practices and seem to be more appropriate for shared decision-making.
Abstract
Cited 7 times since 2016 (0.8 per year)
source: Scopus
Journal of geriatric cardiology : JGC,
Volume 13, Issue 1, 1 1 2016, Pages 31-36
Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years.
van der Kley F, van Rosendael PJ, Katsanos S, Kamperidis V, Marsan NA, Karalis I, de Weger A, Palmen M, Bax JJ, Schalij MJ, Delgado V
Objective: To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old. Methods: A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients. Re...
Abstract
Cited 1 times since 2016 (0.1 per year)
source: EuropePMC
World journal of emergency medicine,
Volume 7, Issue 1, 1 1 2016, Pages 30-34
Comparison of intravenous pantoprazole and ranitidine in patients with dyspepsia presented to the emergency department: a randomized, double blind, controlled trial.
Senay E, Eken C, Yildiz M, Yilmaz D, Alkan E, Akin M, Serinken M
Background: This study aimed to compare pantoprazole, a proton-pomp inhibitors (PPIs), and ranitidine, a H2 receptor antagonists (H2RA), in ceasing dyspeptic symptoms in the emergency department (ED). Methods: This randomized, double-blinded study compared the effectiveness of 50 mg ranitidine (Ulcuran(®)) and 40 mg pantoprazole (Pantpas(®)), given in a 100 mL saline solution by an intravenous rapid infusion within 2-4 minutes in patients with dyspepsia presented to the ED. Pain intensity was me...
Abstract
Cited 10 times since 2016 (1.1 per year)
source: EuropePMC
Journal of applied oral science : revista FOB,
Volume 24, Issue 1, 1 1 2016, Pages 67-75
Lactobacillus rhamnosus could inhibit Porphyromonas gingivalis derived CXCL8 attenuation.
Mendi A, Köse S, Uçkan D, Akca G, Yilmaz D, Aral L, Gültekin SE, Eroğlu T, Kiliç E, Uçkan S
Unlabelled: An increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. P. gingivalis has been noted to have a different way of interacting with the innate immune response of the host compared to other pathogenic bacteria, which is a recognized feature that inhibits CXCL8 expression. Objective: The aim of the study was to determine if P. gingivalis infection modulates the...
Abstract
Cited 9 times since 2015 (1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 117, Issue 6, 30 5 2016, Pages 887-893
Value of Coronary Computed Tomography Angiography in Tailoring Aspirin Therapy for Primary Prevention of Atherosclerotic Events in Patients at High Risk With Diabetes Mellitus.
Dimitriu-Leen AC, Scholte AJ, van Rosendael AR, van den Hoogen IJ, Kharagjitsingh AV, Wolterbeek R, Knuuti J, Kroft LJ, Delgado V, Jukema JW, de Graaf MA, Bax JJ
Aspirin use for primary prevention in patients at high risk with diabetes mellitus (DM) is often recommended under the assumption that most patients with DM have coronary artery disease (CAD). However, not all patients may have CAD. The present study evaluated, in 425 patients at high risk with DM (without chest pain syndrome or a history of cardiac disease), the prevalence of CAD on coronary computed tomography angiography (CTA). Moreover, the association between the presence and number of trad...
Abstract
Cited 6 times since 2015 (0.7 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 49, Issue 6, 30 5 2016, Pages 1564-1570
Twenty-year experience with the Ross-Konno procedure.
Schneider AW, Bökenkamp R, Bruggemans EF, Hazekamp MG
Objectives: The Ross-Konno procedure is a last resort for patients with complex multilevel left ventricular outflow tract obstruction (LVOTO) often having other cardiovascular anomalies. It is typically preceded by multiple surgeries. Literature is scarce on long-term follow-up series. Therefore, we have reviewed our 20-year experience with this procedure in order to provide insights in patients' outcomes and to optimize patient selection. Methods: Between January 1995 and December 2014, 48...
Abstract
Cited 56 times since 2015 (6.1 per year)
source: EuropePMC
Journal of thrombosis and haemostasis : JTH,
Volume 14, Issue 1, 29 5 2016, Pages 121-128
Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism.
Klok FA, Dzikowska-Diduch O, Kostrubiec M, Vliegen HW, Pruszczyk P, Hasenfuß G, Huisman MV, Konstantinides S, Lankeit M
Unlabelled: Essentials Predicting chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism is hard. We studied 772 patients with pulmonary embolism who were followed for CTEPH (incidence 2.8%). Logistic regression analysis revealed 7 easily collectable clinical variables that combined predict CTEPH. Our score identifies patients at low (0.38%) or higher (10%) risk of CTEPH. Summary: Introduction Validated risk factors for the diagnosis of chronic thromboembolic pulmonary hy...
Abstract
Cited 27 times since 2015 (2.9 per year)
source: EuropePMC
Frontiers in cellular and infection microbiology,
Volume 5, 24 4 2015, Pages 99
Salivary Antimicrobial Peptides in Early Detection of Periodontitis.
Güncü GN, Yilmaz D, Könönen E, Gürsoy UK
In the pathogenesis of periodontitis, an infection-induced inflammatory disease of the tooth-supporting tissues, there is a complex interaction between the subgingival microbiota and host tissues. A periodontal diagnostic tool for detecting the initiation and progression of the disease, monitoring the response to therapy, or measuring the degree of susceptibility to future disease progression has been of interest for a long time. The value of various enzymes, proteins, and immunoglobulins, which...
Abstract
Cited 3 times since 2015 (0.3 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 17, Issue 3, 20 3 2015, Pages 353
Four-dimensional flow cardiovascular magnetic resonance for the evaluation of the atrial baffle after Mustard repair.
van der Palen RL, Westenberg JJ, Hazekamp MG, Kuipers IM, Roest AA
Abstract
Cited 22 times since 2015 (2.4 per year)
source: EuropePMC
European journal of clinical pharmacology,
Volume 72, Issue 4, 19 3 2015, Pages 431-437
Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies.
Trompet S, Postmus I, Slagboom PE, Heijmans BT, Smit RA, Maier AB, Buckley BM, Sattar N, Stott DJ, Ford I, Westendorp RG, de Craen AJ, Jukema JW
Purpose: In pharmacogenetic research, genetic variation in non-responders and high responders is compared with the aim to identify the genetic loci responsible for this variation in response. However, an important question is whether the non-responders are truly biologically non-responsive or actually non-adherent? Therefore, the aim of this study was to describe, within the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), characteristics of both non-responders and high respond...
Abstract
Cited 51 times since 2015 (5.5 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 10, 18 3 2015, Pages 811-816
Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain.
Kamperidis V, Marsan NA, Delgado V, Bax JJ
Aims: Left ventricular (LV) ejection fraction (LVEF) is currently considered for the decision making of patients with mitral regurgitation (MR). However, LVEF represents change in LV volume between end-diastole and end-systole but does not characterize the intrinsic function of the myocardium. In contrast, speckle-tracking global longitudinal strain (GLS) characterizes myocardial deformation. The present study evaluated whether LV GLS may detect further impairment in LV systolic function in dila...
Abstract
Cited 3 times since 2015 (0.3 per year)
source: EuropePMC
Heart rhythm,
Volume 13, Issue 4, 14 2 2015, Pages 860-869
QRS prolongation after premature stimulation is associated with polymorphic ventricular tachycardia in nonischemic cardiomyopathy: Results from the Leiden Nonischemic Cardiomyopathy Study.
Piers SR, Askar SF, Venlet J, Androulakis AF, Kapel GF, de Riva Silva M, Jongbloed JJ, van Tintelen JP, Schalij MJ, Pijnappels DA, Zeppenfeld K
Background: Progressive activation delay after premature stimulation has been associated with ventricular fibrillation in nonischemic cardiomyopathy (NICM). Objectives: The objectives of this study were (1) to investigate prolongation of the paced QRS duration (QRSd) after premature stimulation as a marker of activation delay in NICM, (2) to assess its relation to induced ventricular arrhythmias, and (3) to analyze its underlying substrate by late gadolinium enhancement cardiac magnetic resonanc...
Abstract
Cited 12 times since 2015 (1.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 117, Issue 5, 14 2 2015, Pages 768-774
Prognostic Value of Coronary Computed Tomography Imaging in Patients at High Risk Without Symptoms of Coronary Artery Disease.
Dedic A, Ten Kate GJ, Roos CJ, Neefjes LA, de Graaf MA, Spronk A, Delgado V, van Lennep JE, Moelker A, Ouhlous M, Scholte AJ, Boersma E, Sijbrands EJ, Nieman K, Bax JJ, de Feijter PJ
At present, traditional risk factors are used to guide cardiovascular management of asymptomatic subjects. Intensified surveillance may be warranted in those identified as high risk of developing cardiovascular disease (CVD). This study aims to determine the prognostic value of coronary computed tomography (CT) angiography (CCTA) next to the coronary artery calcium score (CACS) in patients at high CVD risk without symptoms suspect for coronary artery disease (CAD). A total of 665 patients at hig...
Abstract
Cited 9 times since 2015 (1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 32, Issue 4, 14 2 2015, Pages 543-552
Enhanced characterization of calcified areas in intravascular ultrasound virtual histology images by quantification of the acoustic shadow: validation against computed tomography coronary angiography.
Broersen A, de Graaf MA, Eggermont J, Wolterbeek R, Kitslaar PH, Dijkstra J, Bax JJ, Reiber JH, Scholte AJ
We enhance intravascular ultrasound virtual histology (VH) tissue characterization by fully automatic quantification of the acoustic shadow behind calcified plaque. VH is unable to characterize atherosclerosis located behind calcifications. In this study, the quantified acoustic shadows are considered calcified to approximate the real dense calcium (DC) plaque volume. In total, 57 patients with 108 coronary lesions were included. A novel post-processing step is applied on the VH images to quanti...
Abstract
Cited 1 times since 2015 (0.1 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 23, Issue 5, 11 2 2015, Pages 1176-1179
One-stop-shop cardiac CT: Calcium score, angiography, and myocardial perfusion.
van Rosendael AR, Dimitriu-Leen AC, Bax JJ, Kroft LJ, Scholte AJHA
Abstract
Cited 26 times since 2015 (2.8 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 24, Issue 1, 9 2 2015, Pages 195-206
<sup>18</sup>F-FDG positron emission tomography/computed tomography in infective endocarditis.
Salomäki SP, Saraste A, Kemppainen J, Bax JJ, Knuuti J, Nuutila P, Seppänen M, Roivainen A, Airaksinen J, Pirilä L, Oksi J, Hohenthal U
Background: The diagnosis of infective endocarditis (IE), especially the diagnosis of prosthetic valve endocarditis (PVE) is challenging since echocardiographic findings are often scarce in the early phase of the disease. We studied the use of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in IE. Methods: Sixteen patients with suspected PVE and 7 patients with NVE underwent visual evaluation of 18F-FDG-PET/CT. 18F-FDG uptake was measured also...
Abstract
Cited 22 times since 2015 (2.4 per year)
source: EuropePMC
Heart rhythm,
Volume 13, Issue 4, 8 2 2015, Pages 905-912
Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus.
Ten Sande JN, Postema PG, Boekholdt SM, Tan HL, van der Heijden JF, de Groot NM, Volders PG, Zeppenfeld K, Boersma LV, Nannenberg EA, Christiaans I, Wilde AA
Background: Familial idiopathic ventricular fibrillation (IVF) is a severe disease entity and is notoriously difficult to manage because there are no clinical risk indicators for premature cardiac arrest. Previously, we identified a link between familial IVF and a risk haplotype on chromosome 7q36 (involving the arrhythmia gene DPP6). Objective: The purpose of this study was to expand our knowledge of familial IVF and to discuss its (extended) clinical characteristics. Methods: We studied 601 fa...
Abstract
Cited 20 times since 2015 (2.2 per year)
source: EuropePMC
Tuberculosis (Edinburgh, Scotland),
Volume 97, 8 2 2015, Pages 163-171
KLRG1 and PD-1 expression are increased on T-cells following tuberculosis-treatment and identify cells with different proliferative capacities in BCG-vaccinated adults.
Boer MC, van Meijgaarden KE, Goletti D, Vanini V, Prins C, Ottenhoff TH, Joosten SA
In cancer and chronic infectious diseases, immune checkpoint-blockade of inhibitory receptors can enhance T-cell immunity. In tuberculosis (TB), a chronic infectious disease, prolonged antigen exposure can potentially drive terminal T-cell differentiation towards functional 'exhaustion': in human TB T-cells express PD-1 (programmed cell death protein-1) and CTLA-4 (cytotoxic T-lymphocyte-associated protein-4). However, in murine TB not PD-1 but rather killer cell lectin-like receptor s...
Abstract
Cited 6 times since 2015 (0.6 per year)
source: EuropePMC
International journal of surgery case reports,
Volume 19, 7 1 2015, Pages 8-10
Traumatic rupture of a Meckel's diverticulum due to blunt abdominal trauma in a soccer game: A case report.
Tummers WS, van der Vorst JR, Swank DJ
Introduction: a Meckel's diverticulum is one of the most common congenital anomalies of the digestive tract. The reported lifetime complication rate is 4%, mostly due to hemorrhage, obstruction, perforation or inflammation. A symptomatic Meckel's diverticulum due to rupture after blunt abdominal trauma is very rare. We believe this case report is the first reporting a rupture of a Meckel's diverticulum after a low velocity blunt abdominal trauma and outlining the importance of a t...
Abstract
