Research

Publications

Below you can find a list of our published research.

9618 results

Cited 37 times since 2011 (2.6 per year) source: EuropePMC

Pediatric dermatology, Volume 28, Issue 2, 1 1 2011, Pages 169-171 Hypoglycemia as a result of propranolol during treatment of infantile hemangioma: a case report. Breur JM, de Graaf M, Breugem CC, Pasmans SG

Propranolol is a new and promising treatment for hemangiomas of infancy. We report of a patient in whom steroid maintenance therapy is successfully tapered after introduction of propranolol. This patient, however, developed symptomatic hypoglycemic events presumably because of a concurrent deficiency of epinephrine and cortisol as a direct result of both beta-blockage by propranolol and adrenal insufficiency as a result of prednisone use. Extreme care should be taken in patients treated with bot... Abstract

Cited 8 times since 2011 (0.6 per year) source: EuropePMC

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Volume 17, Issue 3, 1 1 2011, Pages 261-269 Clinical value of myocardial perfusion scintigraphy as a screening tool in liver transplant candidates. Oprea-Lager DE, Sorgdrager BJ, Jukema JW, Scherptong RW, Ringers J, Coenraad MJ, van Hoek B, Stokkel MP

A cardiac evaluation before orthotopic liver transplantation (OLT) is imperative. Previous investigations have demonstrated that mild to moderate reversible perfusion defects on myocardial perfusion scintigraphy (MPS) in general are associated with a low risk for perioperative cardiac events. The objective of this study was to assess any perfusion defects in consecutive patients with chronic liver disease who were undergoing OLT. OLT candidates underwent extensive cardiovascular screening that i... Abstract

Cited 60 times since 2011 (4.1 per year) source: EuropePMC

The Journal of clinical psychiatry, Volume 72, Issue 3, 1 1 2011, Pages 288-294 Psychological characteristics of chronic depression: a longitudinal cohort study. Wiersma JE, van Oppen P, van Schaik DJ, van der Does AJ, Beekman AT, Penninx BW

Background: Few studies have investigated the importance of psychological characteristics for chronicity of depression. Knowledge about psychological differences between chronically depressed persons and nonchronically depressed persons may help to improve treatment of chronic depression. This is the first study to simultaneously compare in large samples various psychological characteristics between chronically depressed and nonchronically depressed adults. Method: Baseline data were drawn from... Abstract

Cited 11 times since 2011 (0.8 per year) source: EuropePMC

Journal of dairy science, Volume 94, Issue 3, 1 1 2011, Pages 1347-1354 The effect of bluetongue virus serotype 8 on milk production and somatic cell count in Dutch dairy cows in 2008. Santman-Berends IM, Hage JJ, Lam TJ, Sampimon OC, van Schaik G

The effect of bluetongue virus serotype 8 (BTV-8) infections was quantified on milk production and udder health. From July 2008 to December 2008, 1,074 seronegative cows in 15 herds that were not vaccinated against BTV-8 were tested every 3 wk for BTV-8 antibodies. Sampling stopped when cows seroconverted. Test-day records were provided and 3 traits were defined to evaluate the effect of BTV-8 on milk production and udder health: 1) the difference between observed and predicted fat- and protein-... Abstract

Cited 1 times since 2011 (0.1 per year) source: EuropePMC

Australian family physician, Volume 40, Issue 3, 1 1 2011, Pages 89 Rural health education. van Schaik K

Thirty-five health sciences students and four mentors, including myself, were participating in a 'Country Week' rural health experience in the catchment area of the Murchison River in the midwest of Western Australia. The Murchison, once a gold mining centre, now has a population of about 2500, many of whom live on sheep and cattle stations. Abstract

Cited 9 times since 2011 (0.6 per year) source: EuropePMC

Expert opinion on biological therapy, Volume 11, Issue 3, 1 1 2011, Pages 329-342 Immunotherapy of multifocal motor neuropathy. Eftimov F, Van Schaik IN

Introduction: Multifocal motor neuropathy (MMN) is an immune-mediated disease, which usually runs a chronic course. Current treatments are aiming at modulation of the immune response to maintain functional status. Although patients can remain stable with prolonged maintenance intravenous immunoglobuin (IVIg) treatment, most patients slowly deteriorate over many years despite increasing IVIg doses. Areas covered: The paper identifies studies since 1985 for patients with MMN. Randomised and non-ra... Abstract

Cited 26 times since 2011 (1.8 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 4, Issue 3, 1 1 2011, Pages 246-256 Feasibility of diastolic function assessment with cardiac CT: feasibility study in comparison with tissue Doppler imaging. Boogers MJ, van Werkhoven JM, Schuijf JD, Delgado V, El-Naggar HM, Boersma E, Nucifora G, van der Geest RJ, Paelinck BP, Kroft LJ, Reiber JH, de Roos A, Bax JJ, Lamb HJ

Objectives: This study aimed to demonstrate the feasibility of multidetector row computed tomography (CT) for assessment of diastolic function in comparison with 2-dimensional (2D) echocardiography using tissue Doppler imaging (TDI). Background: Diastolic left ventricular (LV) function plays an important role in patients with cardiovascular disease. 2D echocardiography using TDI has been used most commonly to evaluate diastolic LV function. Although the role of cardiac CT imaging for evaluation... Abstract

Cited 8 times since 2011 (0.6 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 27, Issue 8, 26 4 2011, Pages 1179-1193 Role of computed tomography imaging for transcatheter valvular repair/insertion. Ewe SH, Klautz RJ, Schalij MJ, Delgado V

During the last decade, the development of transcatheter based therapies has provided feasible therapeutic options for patients with symptomatic severe valvular heart disease who are deemed inoperable. The promising results of many nonrandomized series and recent landmark trials have increased the number of percutaneous transcatheter valve procedures in high operative risk patients. Pre-procedural imaging of the anatomy of the aortic or mitral valve and their spatial relationships is crucial to... Abstract

Cited 81 times since 2011 (5.6 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 97, Issue 22, 25 4 2011, Pages 1847-1851 Impact of left atrial fibrosis and left atrial size on the outcome of catheter ablation for atrial fibrillation. den Uijl DW, Delgado V, Bertini M, Tops LF, Trines SA, van de Veire NR, Zeppenfeld K, Schalij MJ, Bax JJ

Background: Left atrial (LA) dilatation is an important risk factor for recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA). However, the clinical applications to select patients eligible for RFCA according to LA size is limited. Additional pre-procedural assessment of LA fibrosis might improve patient selection for RFCA. Objective: To investigate the impact of LA size and LA fibrosis on the outcome of RFCA for AF. Methods: One hundred and seventy consecutive pat... Abstract

Cited 10 times since 2011 (0.7 per year) source: EuropePMC

Atherosclerosis, Volume 216, Issue 2, 24 4 2011, Pages 365-369 Exercise ankle brachial index adds important prognostic information on long-term out-come only in patients with a normal resting ankle brachial index. de Liefde II, Klein J, Bax JJ, Verhagen HJ, van Domburg RT, Poldermans D

Background: The clinical value of exercise ankle brachial index (ABI) is still unclear, especially in patients with normal resting ABI. Method: 2164 patients performed a single-stage treadmill exercise test to diagnose or evaluate PAD. The population was divided into two groups: a normal resting ABI (resting ABI≥0.90) and PAD (resting ABI Abstract

Cited 46 times since 2011 (3.2 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 24, Issue 4, 24 4 2011, Pages 405-413 Quantitative analysis of mitral valve apparatus in mitral valve prolapse before and after annuloplasty: a three-dimensional intraoperative transesophageal study. Maffessanti F, Marsan NA, Tamborini G, Sugeng L, Caiani EG, Gripari P, Alamanni F, Jeevanandam V, Lang RM, Pepi M

Background: Intraoperative real-time three-dimensional transesophageal echocardiography has been shown useful in the evaluation of the mitral valve (MV) apparatus, and dedicated commercial software allows its quantitative assessment. The aims of this study were to (1) quantify the effects induced by prolapse on MV anatomy in the presence of fibroelastic deficiency (FED) or Barlow's disease (BD), (2) assess the effect of surgery on the MV apparatus, and (3) investigate the potential role of... Abstract

Cited 129 times since 2011 (8.9 per year) source: EuropePMC

Circulation research, Volume 108, Issue 5, 24 4 2011, Pages 582-592 Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction. Arslan F, Smeets MB, Riem Vis PW, Karper JC, Quax PH, Bongartz LG, Peters JH, Hoefer IE, Doevendans PA, Pasterkamp G, de Kleijn DP

Rationale: The extracellular matrix may induce detrimental inflammatory responses on degradation, causing adverse cardiac remodeling and heart failure. The extracellular matrix protein fibronectin-EDA (EIIIA; EDA) is upregulated after tissue injury and may act as a "danger signal" for leukocytes to cause adverse cardiac remodeling after infarction. Objective: In the present study, we evaluated the role of EDA in regulation of postinfarct inflammation and repair after myocardial infarct... Abstract

Cited 15 times since 2011 (1 per year) source: EuropePMC

American journal of obstetrics and gynecology, Volume 204, Issue 5, 23 4 2011, Pages 396.e1-396.e14 Perinatal risk indicators for long-term neurological morbidity among preterm neonates. Teune MJ, van Wassenaer AG, van Dommelen P, Mol BW, Opmeer BC, Dutch POPS-19 Collaborative Study Group

Objective: Many obstetric interventions are performed to improve long-term neonatal outcome. However, long-term neonatal outcome is usually not a primary outcome because it is time-consuming and expensive. The aim of this project was to identify different perinatal risk indicators and to develop prediction models for neurologic morbidity at 2 and 5 years of age. Study design: Data from a Dutch cohort study of preterm and small-for-gestational-age infants was used. Neonates who were born in The N... Abstract

Cited 12 times since 2011 (0.8 per year) source: EuropePMC

BMC geriatrics, Volume 11, 22 4 2011, Pages 8 Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Freeman DJ, Robertson M, Brown EA, Rumley A, Tobias ES, Frölich M, Slagboom PE, Jukema JW, de Craen AJ, Sattar N, Ford I, Gaw A, Greer IA, Lowe GD, Stott DJ

Background: Venous thromboembolic events (VTE), including deep venous thrombosis and pulmonary embolism, are common in older age. It has been suggested that statins might reduce the risk of VTE however positive results from studies of middle aged subjects may not be generalisable to elderly people. We aimed to determine the effect of pravastatin on incident VTE in older people; we also studied the impact of clinical and plasma risk variables. Methods: This study was an analysis of incident VTE u... Abstract

Cited 13 times since 2011 (0.9 per year) source: EuropePMC

International psychogeriatrics, Volume 23, Issue 6, 22 4 2011, Pages 969-978 Feasibility and effectiveness of activity-scheduling as a guided self-help intervention for the prevention of depression and anxiety in residents in homes for the elderly: a pragmatic randomized controlled trial. Dozeman E, van Schaik DJ, van Marwijk HW, Stek ML, Beekman AT, van der Horst HE

Background: Elderly people living in residential homes are at high risk for developing major depressive and anxiety disorders, and therefore deserve attention in terms of preventive interventions. We evaluated the feasibility and effectiveness of a guided self-help intervention for the prevention of depression and anxiety in these residents. Methods: We conducted a pragmatic randomized controlled trial in two parallel groups comparing the intervention with usual care in 14 residential homes in a... Abstract

Cited 27 times since 2011 (1.9 per year) source: EuropePMC

European journal of pain (London, England), Volume 15, Issue 8, 22 4 2011, Pages 822-829 The relation between small nerve fibre function, age, disease severity and pain in Fabry disease. Biegstraaten M, Binder A, Maag R, Hollak CE, Baron R, van Schaik IN

Background: Small fibre neuropathy supposedly causes pain in Fabry patients, but the relationship between small nerve fibre function and pain severity is unclear. Methods: A cohort of 15 male and 33 female Fabry patients was studied making use of a quantitative sensory testing protocol, disease severity measures and pain scales to investigate the relationship between nerve fibre function, age, disease severity and pain intensity. Results: Male Fabry patients exhibited an abnormal cold detection... Abstract

Cited 54 times since 2011 (3.7 per year) source: EuropePMC

Molecular biology and evolution, Volume 28, Issue 8, 18 3 2011, Pages 2275-2288 Sex-biased dispersal and volcanic activities shaped phylogeographic patterns of extant Orangutans (genus: Pongo). Nater A, Nietlisbach P, Arora N, van Schaik CP, van Noordwijk MA, Willems EP, Singleton I, Wich SA, Goossens B, Warren KS, Verschoor EJ, Perwitasari-Farajallah D, Pamungkas J, Krützen M

The Southeast Asian Sunda archipelago harbors a rich biodiversity with a substantial proportion of endemic species. The evolutionary history of these species has been drastically influenced by environmental forces, such as fluctuating sea levels, climatic changes, and severe volcanic activities. Orangutans (genus: Pongo), the only Asian great apes, are well suited to study the relative impact of these forces due to their well-documented behavioral ecology, strict habitat requirements, and except... Abstract

Cited 36 times since 2011 (2.5 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 31, Issue 5, 17 3 2011, Pages 1033-1040 Toll-like receptor 4 is involved in human and mouse vein graft remodeling, and local gene silencing reduces vein graft disease in hypercholesterolemic APOE*3Leiden mice. Karper JC, de Vries MR, van den Brand BT, Hoefer IE, Fischer JW, Jukema JW, Niessen HW, Quax PH

Objective: The goal of this study was to explore the role of Toll-like receptor 4 (TLR4) in vein graft remodeling and disease. Methods and results: First, expression of TLR4 was analyzed in freshly isolated human saphenous veins (huSV), in freshly isolated huSV ex vivo perfused in an extracorporeal circulation, or in huSV used as coronary vein grafts. Marked induction of focal TLR4 expression was observed in perfused fresh huSV. Moreover, TLR4 was abundantly present in lesions in fresh huSV or i... Abstract

Cited 76 times since 2011 (5.2 per year) source: EuropePMC

Injury, Volume 42, Issue 10, 16 3 2011, Pages 1125-1129 Increased rates of wound complications with locking plates in distal fibular fractures. Schepers T, Van Lieshout EM, De Vries MR, Van der Elst M

Introduction: There is a growing use of locking compression plates in fracture surgery. The current study was undertaken to investigate the wound complication rates of locking versus non-locking plates in distal fibular fractures. Patients and methods: During a 6-year study period all consecutive, closed distal fibular fractures treated with either a locking or a non-locking plate were included and retrospectively analysed for complication related to the fibula. Results: A total of 165 patients... Abstract

Cited 44 times since 2011 (3 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 13, Issue 5, 16 3 2011, Pages 634-639 The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. Macfarlane PW, Murray H, Sattar N, Stott DJ, Ford I, Buckley B, Jukema JW, Westendorp RG, Shepherd J

Aims: Atrial fibrillation/flutter (AF) is the most common arrhythmia in older people. It associates with reduced exercise capacity, increased risk of stroke, and mortality. We aimed to determine retrospectively whether pravastatin reduces the incidence of AF and whether any electrocardiographic measures or clinical conditions might be risk factors for its development. Methods and results: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) was a randomized, double-blind control... Abstract